CY1110381T1 - Πεπτιδια χ-κωνοτοξινης ως αναστολεις των νευρωνικων αμινικων μεταφορεων - Google Patents
Πεπτιδια χ-κωνοτοξινης ως αναστολεις των νευρωνικων αμινικων μεταφορεωνInfo
- Publication number
- CY1110381T1 CY1110381T1 CY20061101621T CY061101621T CY1110381T1 CY 1110381 T1 CY1110381 T1 CY 1110381T1 CY 20061101621 T CY20061101621 T CY 20061101621T CY 061101621 T CY061101621 T CY 061101621T CY 1110381 T1 CY1110381 T1 CY 1110381T1
- Authority
- CY
- Cyprus
- Prior art keywords
- transport inhibitors
- conotoxin peptides
- peptides
- neuronal amine
- amine transport
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Addiction (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Η εφεύρεση σχετίζεται με ένα απομονωμένο, συνθετικό ή ανασυνδυασμένο πεπτίδιο χ-κωνοτοξίνης το οποίο έχει τη δυνατότητα να αναστέλλει έναν αμινικό νευρωνικό μεταφορέα, με νουκλεϊνικά οξέα τα οποία κωδικοποιούν ολόκληρα ή μέρη αυτών των πεπτιδίων, με αντισώματα στα πεπτίδια αυτά και χρήσεις και μεθόδους θεραπείας στις οποίες εμπλέκονται τα πεπτίδια αυτά.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP6274A AUPP627498A0 (en) | 1998-10-02 | 1998-10-02 | Novel peptides - i |
EP99952156A EP1117682B1 (en) | 1998-10-02 | 1999-10-01 | Chi-Conotoxin Peptides as INhibitors of Neuronal Amine Transporters |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110381T1 true CY1110381T1 (el) | 2015-04-29 |
Family
ID=3810492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101621T CY1110381T1 (el) | 1998-10-02 | 2006-11-09 | Πεπτιδια χ-κωνοτοξινης ως αναστολεις των νευρωνικων αμινικων μεταφορεων |
Country Status (13)
Country | Link |
---|---|
US (4) | US6794361B1 (el) |
EP (1) | EP1117682B1 (el) |
JP (2) | JP4447783B2 (el) |
AT (1) | ATE336501T1 (el) |
AU (1) | AUPP627498A0 (el) |
CA (1) | CA2344765A1 (el) |
CY (1) | CY1110381T1 (el) |
DE (1) | DE69932834T2 (el) |
DK (1) | DK1117682T3 (el) |
ES (1) | ES2268885T3 (el) |
NZ (1) | NZ510813A (el) |
PT (1) | PT1117682E (el) |
WO (1) | WO2000020444A1 (el) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPP627498A0 (en) * | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
US6767896B1 (en) | 1999-01-29 | 2004-07-27 | Cognetix, Inc. | Conotoxin peptides |
AU2002245340A1 (en) * | 2001-01-29 | 2002-08-12 | Cognetix, Inc. | B-superfamily conotoxins |
AU2003302610B2 (en) | 2002-12-02 | 2008-03-20 | Xenome Ltd | Novel chi-conotoxin peptides (-II) |
EP1572725B1 (en) * | 2002-12-02 | 2012-02-29 | Xenome Ltd | Chi-conotoxin peptides having a n-terminal pyroglutamic acid |
EP1791857A4 (en) * | 2004-09-09 | 2009-04-08 | Univ Singapore | CONFORMATION CHANGES INVOLVED IN TOXIC FOLDING AND USES THEREOF |
US8188048B2 (en) | 2006-06-23 | 2012-05-29 | Xenome Limited | Combination therapy |
CN103372198B (zh) * | 2012-04-12 | 2016-04-06 | 同济大学 | 用于抑制病毒的多肽抑制剂 |
JP6731044B2 (ja) | 2015-05-22 | 2020-07-29 | クレムソン・ユニバーシティ・リサーチ・ファウンデーション | 生物付着の抑止において用いるためのコノトキシンペプチド |
US10704035B2 (en) | 2015-08-27 | 2020-07-07 | President And Fellows Of Harvard College | Compositions and methods for treatment of pain |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5051403A (en) | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
CA2061665C (en) | 1991-02-25 | 2002-04-16 | Mark Mortensen Foreman | Treatment of lower urinary tract disorders |
DE69225499T2 (de) * | 1991-12-30 | 1999-02-04 | Neurex Corp | Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie |
DK0758900T3 (da) * | 1994-05-09 | 2002-07-29 | William J Binder | Botulinumtoksin til reduktion af migræne-hovedpinesmerter |
RU2158601C2 (ru) | 1994-11-03 | 2000-11-10 | Новартис Аг | Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения |
WO1996040064A1 (en) | 1995-06-07 | 1996-12-19 | Nexstar Pharmaceuticals, Inc. | Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications |
DK1336409T3 (da) | 1995-06-27 | 2007-08-13 | Eisai R&D Man Co Ltd | Sammensætninger af formuleringer til fremstilling af analgesimidler og til hæmning af fremadskridende neuropatiske smertelidelser |
ZA971525B (en) | 1996-02-22 | 1997-10-21 | Neurosearch As | Tropane derivatives, their preparation and use. |
GB9614902D0 (en) | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
CZ288739B6 (cs) | 1996-08-01 | 2001-08-15 | Galena, A. S. | Cyklosporin obsahující léčivé přípravky |
JP2001505878A (ja) | 1996-11-18 | 2001-05-08 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | 心臓血管剤としてのコノトキシンペプチドImIおよびMIIの使用 |
ATE248147T1 (de) | 1997-05-14 | 2003-09-15 | Neurosearch As | Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme |
AUPP627498A0 (en) * | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
WO2000044769A1 (en) | 1999-01-29 | 2000-08-03 | University Of Utah Research Foundation | Conotoxin peptides |
AU2003302610B2 (en) * | 2002-12-02 | 2008-03-20 | Xenome Ltd | Novel chi-conotoxin peptides (-II) |
EP1572725B1 (en) * | 2002-12-02 | 2012-02-29 | Xenome Ltd | Chi-conotoxin peptides having a n-terminal pyroglutamic acid |
-
1998
- 1998-10-02 AU AUPP6274A patent/AUPP627498A0/en not_active Abandoned
-
1999
- 1999-10-01 CA CA002344765A patent/CA2344765A1/en not_active Abandoned
- 1999-10-01 AT AT99952156T patent/ATE336501T1/de active
- 1999-10-01 ES ES99952156T patent/ES2268885T3/es not_active Expired - Lifetime
- 1999-10-01 DE DE69932834T patent/DE69932834T2/de not_active Expired - Lifetime
- 1999-10-01 EP EP99952156A patent/EP1117682B1/en not_active Expired - Lifetime
- 1999-10-01 PT PT99952156T patent/PT1117682E/pt unknown
- 1999-10-01 DK DK99952156T patent/DK1117682T3/da active
- 1999-10-01 WO PCT/AU1999/000844 patent/WO2000020444A1/en active IP Right Grant
- 1999-10-01 NZ NZ510813A patent/NZ510813A/en not_active IP Right Cessation
- 1999-10-01 US US09/787,986 patent/US6794361B1/en not_active Expired - Fee Related
- 1999-10-01 JP JP2000574555A patent/JP4447783B2/ja not_active Expired - Fee Related
-
2004
- 2004-08-13 US US10/918,096 patent/US7326682B2/en not_active Expired - Fee Related
-
2006
- 2006-11-09 CY CY20061101621T patent/CY1110381T1/el unknown
-
2007
- 2007-11-02 US US11/934,723 patent/US7994128B2/en not_active Expired - Fee Related
-
2009
- 2009-10-26 JP JP2009245436A patent/JP2010046088A/ja active Pending
-
2011
- 2011-05-25 US US13/115,711 patent/US20120277166A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000020444A1 (en) | 2000-04-13 |
JP2002526098A (ja) | 2002-08-20 |
DK1117682T3 (da) | 2006-12-27 |
DE69932834D1 (de) | 2006-09-28 |
CA2344765A1 (en) | 2000-04-13 |
US7326682B2 (en) | 2008-02-05 |
JP2010046088A (ja) | 2010-03-04 |
US6794361B1 (en) | 2004-09-21 |
US7994128B2 (en) | 2011-08-09 |
EP1117682A4 (en) | 2001-12-12 |
DE69932834T2 (de) | 2007-08-23 |
US20090275498A1 (en) | 2009-11-05 |
JP4447783B2 (ja) | 2010-04-07 |
EP1117682A1 (en) | 2001-07-25 |
ES2268885T3 (es) | 2007-03-16 |
PT1117682E (pt) | 2006-12-29 |
US20050054827A1 (en) | 2005-03-10 |
US20120277166A1 (en) | 2012-11-01 |
EP1117682B1 (en) | 2006-08-16 |
NZ510813A (en) | 2003-08-29 |
ATE336501T1 (de) | 2006-09-15 |
AUPP627498A0 (en) | 1998-10-22 |
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