DE69932180D1 - Verfahren und zusammensetzungen zur schmerzbehandlung - Google Patents

Verfahren und zusammensetzungen zur schmerzbehandlung

Info

Publication number
DE69932180D1
DE69932180D1 DE69932180T DE69932180T DE69932180D1 DE 69932180 D1 DE69932180 D1 DE 69932180D1 DE 69932180 T DE69932180 T DE 69932180T DE 69932180 T DE69932180 T DE 69932180T DE 69932180 D1 DE69932180 D1 DE 69932180D1
Authority
DE
Germany
Prior art keywords
pain
patient
compositions
dose
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932180T
Other languages
English (en)
Other versions
DE69932180T2 (de
Inventor
M Cameron
C Allen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proteome Sciences Inc
Original Assignee
Proteome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteome Sciences Inc filed Critical Proteome Sciences Inc
Application granted granted Critical
Publication of DE69932180D1 publication Critical patent/DE69932180D1/de
Publication of DE69932180T2 publication Critical patent/DE69932180T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements
    • G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C12Q1/46—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase involving cholinesterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01007—Acetylcholinesterase (3.1.1.7)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G01N33/944—Acetylcholine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/30—Naphthol derivatives, e.g. alpha-naphthyl-esters, i.e. alpha-NE, beta-naphthyl-esters, i.e. beta-NE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69932180T 1998-11-23 1999-11-22 Verfahren und zusammensetzungen zur schmerzbehandlung Expired - Lifetime DE69932180T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10950498P 1998-11-23 1998-11-23
US109504P 1998-11-23
US14125599P 1999-06-30 1999-06-30
US141255P 1999-06-30
PCT/US1999/027582 WO2000031290A1 (en) 1998-11-23 1999-11-22 Methods and compositions for pain management

Publications (2)

Publication Number Publication Date
DE69932180D1 true DE69932180D1 (de) 2006-08-10
DE69932180T2 DE69932180T2 (de) 2007-06-14

Family

ID=26807037

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932180T Expired - Lifetime DE69932180T2 (de) 1998-11-23 1999-11-22 Verfahren und zusammensetzungen zur schmerzbehandlung

Country Status (10)

Country Link
US (1) US6764831B2 (de)
EP (1) EP1133571B1 (de)
AT (1) ATE331809T1 (de)
AU (1) AU2027600A (de)
CA (1) CA2351877C (de)
DE (1) DE69932180T2 (de)
DK (1) DK1133571T3 (de)
ES (1) ES2264278T3 (de)
MX (1) MXPA01005154A (de)
WO (1) WO2000031290A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6659968B1 (en) * 2000-06-01 2003-12-09 Advanced Bionics Corporation Activity monitor for pain management efficacy measurement
US6690397B1 (en) * 2000-06-05 2004-02-10 Advanced Neuromodulation Systems, Inc. System for regional data association and presentation and method for the same
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7131004B1 (en) * 2001-08-31 2006-10-31 Silicon Image, Inc. Method and apparatus for encrypting data transmitted over a serial link
WO2003039342A2 (en) * 2001-11-06 2003-05-15 Millennium Pharmaceuticals, Inc. Methods and compositions to treat pain and painful disorders using 577, 20739 or 57145
CA2465103C (en) 2002-08-09 2011-04-26 Taisho Pharmaceutical Co., Ltd. Use of a prostaglandin derivative as an anti-pruritic agent
US7155279B2 (en) * 2003-03-28 2006-12-26 Advanced Bionics Corporation Treatment of movement disorders with drug therapy
GB0320728D0 (en) * 2003-09-04 2003-10-08 Kilminster Shaun Test
US20060129069A1 (en) * 2004-12-14 2006-06-15 Apkarian A V Apparatus and method for pain measurement
US10042980B2 (en) * 2005-11-17 2018-08-07 Gearbox Llc Providing assistance related to health
US20070112592A1 (en) * 2005-11-17 2007-05-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Payments in providing assistance related to health
US8468029B2 (en) * 2005-11-17 2013-06-18 The Invention Science Fund I, Llc Subscriptions for assistance related to health
US8532938B2 (en) 2005-11-17 2013-09-10 The Invention Science Fund I, Llc Testing-dependent administration of a nutraceutical
US20080082272A1 (en) * 2005-11-30 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems and methods related to nutraceuticals
US20070299693A1 (en) * 2006-06-23 2007-12-27 Searete Llc, A Limited Liability Corporation Customized visual marking for medication labeling
US8297028B2 (en) * 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US8000981B2 (en) * 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US7974856B2 (en) * 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US8340944B2 (en) 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US7927787B2 (en) 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
CA2631675A1 (en) * 2005-11-30 2007-06-21 The University Of North Carolina At Chapel Hill Identification of genetic polymorphic variants associated with somatosensory disorders and methods of using the same
US10296720B2 (en) 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US7827042B2 (en) 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US20080103746A1 (en) 2005-11-30 2008-05-01 Searete Llc, A Limited Liability Corporation Systems and methods for pathogen detection and response
US20070287991A1 (en) * 2006-06-08 2007-12-13 Mckay William F Devices and methods for detection of markers of axial pain with or without radiculopathy
US9757476B2 (en) * 2006-06-08 2017-09-12 Warsaw Orthopedic, Inc. Compositions and methods for diagnosis of axial pain with or without radiculopathy
US8333697B2 (en) 2006-06-08 2012-12-18 Warsaw Orthopedic, Inc. Diagnostic kits and methods for diagnosis of axial pain with or without radiculopathy
US20080086338A1 (en) * 2006-06-23 2008-04-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Customized visual marking for medication labeling
US20070299695A1 (en) * 2006-06-23 2007-12-27 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Customized visual marking for medication labeling
US20080086339A1 (en) * 2006-06-23 2008-04-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Customized visual marking for medication labeling
US20090263370A1 (en) * 2006-11-30 2009-10-22 Guoliang Tao Methods for treating tachykinin-mediated diseases with cholinesterase
CN101190330A (zh) * 2006-11-30 2008-06-04 深圳市鼎兴生物医药技术开发有限公司 胆碱酯酶在拮抗速激肽药物中的应用
US10031126B2 (en) 2013-04-04 2018-07-24 The Regents Of The University Of California System and method for utilizing exhaled breath for monitoring inflammatory states
US11751783B2 (en) * 2021-06-04 2023-09-12 Mirza Faizan System and method for mental state determination

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DE1598739C3 (de) 1965-01-26 1973-10-11 Merck Patent Gmbh, 6100 Darmstadt Mittel zur Bestimmung der Chohnesteraseaktivitat im Serum
US3433712A (en) 1965-01-28 1969-03-18 Horace W Gerarde Cholinesterase test
US3378463A (en) 1965-06-22 1968-04-16 Army Usa Method of measuring enzyme activity
US3410756A (en) * 1966-05-27 1968-11-12 Army Usa Naphthyl esters as fluorogenic substrates for enzymes
US3438866A (en) 1967-03-21 1969-04-15 Pfizer & Co C Serum cholinesterase test
US3928594A (en) * 1974-06-24 1975-12-23 Albert W Cook Method of alleviating symptoms of multiple scleroisis
DE2914721A1 (de) 1978-04-17 1979-10-18 Kyowa Hakko Kogyo Kk Verfahren zur bestimmung der cholinesterase-aktivitaet sowie fuer dieses verfahren verwendbare cholin-derivate
JPS5935599B2 (ja) 1980-12-25 1984-08-29 株式会社 シノテスト研究所 コリンエステラ−ゼ活性測定法
JPS603839B2 (ja) 1981-04-08 1985-01-30 富士レビオ株式会社 コリンエステラ−ゼの活性測定法
JPS58155099A (ja) 1982-03-12 1983-09-14 Unitika Ltd コリンエステラ−ゼ定量用試薬
US4499185A (en) 1982-05-17 1985-02-12 Miles Laboratories, Inc. Test for esterase activity in a liquid sample
JPS60238000A (ja) 1984-05-10 1985-11-26 Nitto Boseki Co Ltd 新規なコリンエステラ−ゼ活性測定法
JPH0650997B2 (ja) 1986-04-15 1994-07-06 日東紡績株式会社 コリンエステラ−ゼ活性の新規測定方法
US4889797A (en) 1986-05-28 1989-12-26 Fuji Photo Film Co., Ltd. Dry analytical element having a spread control area for assaying enzyme activity
JPH0662521B2 (ja) * 1988-02-24 1994-08-17 日東紡績株式会社 新規コリン誘導体及びそれを用いた血清コリンエステラーゼ活性測定法
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
AU667462B2 (en) * 1990-11-30 1996-03-28 Monoclonetics International Incorporated Methods for the diagnosis of chronic lower back and cervical pain
US5272061A (en) 1991-09-20 1993-12-21 Eastman Kodak Company Assay for serum cholinesterase activity

Also Published As

Publication number Publication date
ATE331809T1 (de) 2006-07-15
ES2264278T3 (es) 2006-12-16
US6764831B2 (en) 2004-07-20
DK1133571T3 (da) 2006-10-23
WO2000031290A1 (en) 2000-06-02
EP1133571B1 (de) 2006-06-28
AU2027600A (en) 2000-06-13
DE69932180T2 (de) 2007-06-14
MXPA01005154A (es) 2003-06-06
US20020086343A1 (en) 2002-07-04
EP1133571A1 (de) 2001-09-19
WO2000031290A9 (en) 2001-03-29
CA2351877A1 (en) 2000-06-02
CA2351877C (en) 2012-01-24

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