DE69928110D1 - Trägerhilfstoff - Google Patents

Trägerhilfstoff

Info

Publication number
DE69928110D1
DE69928110D1 DE69928110T DE69928110T DE69928110D1 DE 69928110 D1 DE69928110 D1 DE 69928110D1 DE 69928110 T DE69928110 T DE 69928110T DE 69928110 T DE69928110 T DE 69928110T DE 69928110 D1 DE69928110 D1 DE 69928110D1
Authority
DE
Germany
Prior art keywords
support material
material help
help
whiteness
trehalose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69928110T
Other languages
English (en)
Other versions
DE69928110T2 (de
Inventor
Kazuhiro Oobae
Etsuo Kamada
Shun Ichi Gomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Chemicals Corp
Original Assignee
Asahi Kasei Chemicals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Chemicals Corp filed Critical Asahi Kasei Chemicals Corp
Application granted granted Critical
Publication of DE69928110D1 publication Critical patent/DE69928110D1/de
Publication of DE69928110T2 publication Critical patent/DE69928110T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Glass Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DE69928110T 1998-07-15 1999-07-13 Trägerhilfstoff Expired - Lifetime DE69928110T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP20029598 1998-07-15
JP20029598 1998-07-15
JP32356098 1998-11-13
JP32356098 1998-11-13
PCT/JP1999/003775 WO2000003735A1 (fr) 1998-07-15 1999-07-13 Excipient

Publications (2)

Publication Number Publication Date
DE69928110D1 true DE69928110D1 (de) 2005-12-08
DE69928110T2 DE69928110T2 (de) 2006-07-27

Family

ID=26512084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69928110T Expired - Lifetime DE69928110T2 (de) 1998-07-15 1999-07-13 Trägerhilfstoff

Country Status (10)

Country Link
US (1) US6699845B2 (de)
EP (1) EP1097722B1 (de)
JP (1) JP4748627B2 (de)
KR (1) KR100421264B1 (de)
CN (1) CN1185013C (de)
AT (1) ATE308343T1 (de)
AU (1) AU743109B2 (de)
CA (1) CA2337015C (de)
DE (1) DE69928110T2 (de)
WO (1) WO2000003735A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US20040131672A1 (en) * 2003-01-07 2004-07-08 Nilobon Podhipleux Direct compression pharmaceutical composition containing a pharmaceutically active ingredient with poor flowing properties
EP1460080A1 (de) * 2003-03-21 2004-09-22 Cargill Incorporated Direkt komprimierbare Trehalose in fester Form
US20060177553A1 (en) * 2003-03-26 2006-08-10 Michio Kubota Method of powdering nonsugar component and powdering base
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
JP2007131587A (ja) * 2005-11-11 2007-05-31 Activas Pharma:Kk キノリノン誘導体を有効成分とする医薬組成物、及びその製造方法
JP5420907B2 (ja) * 2005-12-07 2014-02-19 タケダ ニコメド エイエス 予備圧縮されたカルシウム含有化合物
CN100391541C (zh) * 2006-03-16 2008-06-04 南台科技大学 以胶质类食材制造赋形剂的方法
AU2007232098A1 (en) * 2006-03-31 2007-10-11 Rubicon Research Private Limited Directly compressible composite for orally disintegrating tablets
EA030606B1 (ru) 2006-05-04 2018-08-31 Бёрингер Ингельхайм Интернациональ Гмбх Способы приготовления лекарственного средства, содержащего полиморфы
EP1852108A1 (de) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
US20100237530A1 (en) * 2006-06-27 2010-09-23 Daiichi Sankyo Company, Limited Compressed preparation
US20100092564A1 (en) * 2006-12-21 2010-04-15 Jae Han Park Composition of and Method for Preparing Orally Disintegrating Tablets
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
JP5344938B2 (ja) * 2009-01-29 2013-11-20 旭化成ケミカルズ株式会社 崩壊性固形製剤
BR112012012641A2 (pt) 2009-11-27 2020-08-11 Boehringer Ingelheim International Gmbh TRATAMENTO DE PACIENTES DIABÉTICOS GENOTIPADOS COM INIBIDORES DE DPP-lVTAL COMO LINAGLIPTINA
WO2011138421A1 (en) 2010-05-05 2011-11-10 Boehringer Ingelheim International Gmbh Combination therapy
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
SG11201400808YA (en) * 2011-09-21 2014-07-30 Hayashibara Co PRODUCTION METHOD FOR POWDER CONTAINING CRYSTALLINE a, a-TREHALOSE DIHYDRATE
US9522964B2 (en) * 2012-04-03 2016-12-20 Development, Inc. Micronized starch and methods for manufacturing same
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
EP3556220A4 (de) 2017-10-03 2020-06-03 Mizkan Holdings Co., Ltd. Zusammensetzung mit lebensmittelmikropartikelkomplexen und verfahren zur herstellung davon

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762857A (en) 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4678812A (en) 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
DE69331839T2 (de) 1992-01-29 2002-12-12 Takeda Chemical Industries Ltd Schnellösliche Tablette und ihre Herstellung
WO1993015724A1 (en) 1992-02-18 1993-08-19 Nippon Shinyaku Co., Ltd. Fast soluble tablet
JPH069382A (ja) * 1992-04-17 1994-01-18 Takeda Chem Ind Ltd 安定化された固型製剤およびその製造方法
EP0691344B1 (de) 1992-12-28 2003-03-19 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Reinigung von Trehalose
JP3773062B2 (ja) * 1993-01-29 2006-05-10 味の素株式会社 製剤用添加剤
JP3559585B2 (ja) * 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
DE69532110T2 (de) 1994-01-31 2004-09-09 Yamanouchi Pharmaceutical Co., Ltd. Intraoral löslicher formpressling und verfahren zu seiner herstellung
JP3534130B2 (ja) * 1994-03-01 2004-06-07 旭化成ケミカルズ株式会社 医薬品組成物
TW426737B (en) * 1994-06-27 2001-03-21 Hayashibara Biochem Lab Saccharide composition with reduced reducibility, and preparation and uses thereof
JP3616166B2 (ja) 1994-07-19 2005-02-02 株式会社林原生物化学研究所 トレハロースとその製造方法並びに用途
JP2919771B2 (ja) 1995-04-17 1999-07-19 佐藤製薬株式会社 速溶解性錠剤の製造方法及び該製造方法により製造した速溶解性錠剤
JP3418274B2 (ja) 1995-06-05 2003-06-16 日本化薬株式会社 口腔内感触の良好な錠剤
JPH0948726A (ja) 1995-08-07 1997-02-18 Tanabe Seiyaku Co Ltd 口腔内速崩壊性製剤およびその製法
CA2204599A1 (en) 1995-09-07 1997-03-13 Otsuka Pharmaceutical Co., Ltd. Low-pressure tableted effervescent preparation
JP3624038B2 (ja) * 1995-12-11 2005-02-23 株式会社林原生物化学研究所 糖衣固形物及びその製造方法
ATE265205T1 (de) * 1996-02-09 2004-05-15 Quadrant Drug Delivery Ltd Feste arzneimittel enthaltend trehalose
JPH09316006A (ja) 1996-05-29 1997-12-09 Yatsuken:Kk 口腔内溶解性固形製剤
DK0914818T3 (da) 1996-06-14 2005-07-04 Kyowa Hakko Kogyo Kk Intraoralt hurtigt desintegrerbar tablet
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
TW527195B (en) * 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11116464A (ja) 1997-10-09 1999-04-27 Ss Pharmaceut Co Ltd 迅速溶解性固形製剤およびその製造法

Also Published As

Publication number Publication date
AU4651699A (en) 2000-02-07
US6699845B2 (en) 2004-03-02
AU743109B2 (en) 2002-01-17
EP1097722A4 (de) 2002-03-20
DE69928110T2 (de) 2006-07-27
KR20010071883A (ko) 2001-07-31
CA2337015C (en) 2004-09-07
EP1097722B1 (de) 2005-11-02
KR100421264B1 (ko) 2004-03-18
CN1185013C (zh) 2005-01-19
JP4748627B2 (ja) 2011-08-17
EP1097722A1 (de) 2001-05-09
CN1309570A (zh) 2001-08-22
WO2000003735A1 (fr) 2000-01-27
US20020042393A1 (en) 2002-04-11
CA2337015A1 (en) 2000-01-27
ATE308343T1 (de) 2005-11-15

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Legal Events

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