DE69927512D1 - Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers - Google Patents

Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers

Info

Publication number
DE69927512D1
DE69927512D1 DE69927512T DE69927512T DE69927512D1 DE 69927512 D1 DE69927512 D1 DE 69927512D1 DE 69927512 T DE69927512 T DE 69927512T DE 69927512 T DE69927512 T DE 69927512T DE 69927512 D1 DE69927512 D1 DE 69927512D1
Authority
DE
Germany
Prior art keywords
animals
repair
manufacture
pharmaceutical composition
tissues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69927512T
Other languages
English (en)
Other versions
DE69927512T2 (de
Inventor
Slobodan Vukicevic
Vladimir Katic
T Sampath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stryker Corp
Original Assignee
Stryker Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stryker Corp filed Critical Stryker Corp
Application granted granted Critical
Publication of DE69927512D1 publication Critical patent/DE69927512D1/de
Publication of DE69927512T2 publication Critical patent/DE69927512T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1875Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/06Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69927512T 1998-10-06 1999-07-30 Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers Expired - Lifetime DE69927512T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10316198P 1998-10-06 1998-10-06
US103161P 1998-10-06
PCT/US1999/017222 WO2000020021A1 (en) 1998-10-06 1999-07-30 Repair of larynx, trachea, and other fibrocartilaginous tissues

Publications (2)

Publication Number Publication Date
DE69927512D1 true DE69927512D1 (de) 2006-02-09
DE69927512T2 DE69927512T2 (de) 2006-07-06

Family

ID=22293705

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69927512T Expired - Lifetime DE69927512T2 (de) 1998-10-06 1999-07-30 Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers
DE69933686T Expired - Lifetime DE69933686T2 (de) 1998-10-06 1999-07-30 Zusammensetzung zur verwendung in der chemonukleolyse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69933686T Expired - Lifetime DE69933686T2 (de) 1998-10-06 1999-07-30 Zusammensetzung zur verwendung in der chemonukleolyse

Country Status (10)

Country Link
US (2) US20020106362A1 (de)
EP (3) EP1117422B1 (de)
JP (5) JP4768125B2 (de)
AT (2) ATE305310T1 (de)
AU (3) AU770725B2 (de)
CA (2) CA2346375C (de)
DE (2) DE69927512T2 (de)
ES (2) ES2478257T3 (de)
MX (1) MXPA01003538A (de)
WO (2) WO2000020559A1 (de)

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US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US20030153976A1 (en) 1999-10-20 2003-08-14 Cauthen Joseph C. Spinal disc annulus reconstruction method and spinal disc annulus stent
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
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US6812211B2 (en) 2002-03-19 2004-11-02 Michael Andrew Slivka Method for nonsurgical treatment of the intervertebral disc and kit therefor
EP2301564A1 (de) 2002-05-04 2011-03-30 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
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US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
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US20060194726A1 (en) * 2004-05-25 2006-08-31 Rueger David C Methods of treating cartilage defects
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
FR2884437B1 (fr) 2005-04-19 2007-07-20 Commissariat Energie Atomique Dispositif et procede microfluidique de transfert de matiere entre deux phases immiscibles.
JP4907908B2 (ja) * 2005-06-29 2012-04-04 ルネサスエレクトロニクス株式会社 駆動回路及び表示装置
US7485295B2 (en) 2005-09-26 2009-02-03 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase ABCI mutants
JP4599563B2 (ja) * 2005-11-04 2010-12-15 国立大学法人 岡山大学 外耳道再建用成形品及びその製造方法
US20070213718A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070213717A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Biological fusion in the vertebral column
US20070227547A1 (en) * 2006-02-14 2007-10-04 Sdgi Holdings, Inc. Treatment of the vertebral column
US7520888B2 (en) * 2006-02-14 2009-04-21 Warsaw Orthopedic, Inc. Treatment of the vertebral column
US20070258941A1 (en) * 2006-05-02 2007-11-08 Pfister Brian E Methods and compositions for remediation of disc herniation by modifying structure
US20080027554A1 (en) * 2006-07-31 2008-01-31 Talmadge Karen D Kit and methods of treatment of an intervertebral disc
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US20090286289A1 (en) * 2008-03-10 2009-11-19 Pang Danny Z Production of Hyaluronate Unsaturated Disaccharides and its Application
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US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20120122791A1 (en) * 2009-05-01 2012-05-17 Jnc Corporation Substrate for cartilage cultivation using artificial collagen, and method for cartilage regeneration treatment using the substrate
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US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
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US8740982B2 (en) * 2010-10-26 2014-06-03 Kyphon Sarl Devices containing a chemonucleolysis agent and methods for treating an intervertebral disc or spinal arachnoiditis
US8404268B2 (en) 2010-10-26 2013-03-26 Kyphon Sarl Locally targeted anti-fibrotic agents and methods of use
US9414930B2 (en) 2010-10-26 2016-08-16 Kyphon SÀRL Activatable devices containing a chemonucleolysis agent
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Also Published As

Publication number Publication date
JP2002526167A (ja) 2002-08-20
ATE305310T1 (de) 2005-10-15
CA2346375A1 (en) 2000-04-13
MXPA01003538A (es) 2005-09-08
EP1119611B1 (de) 2006-10-18
EP2374870A2 (de) 2011-10-12
AU2004202345B2 (en) 2007-12-13
EP1117422A1 (de) 2001-07-25
EP2374870B1 (de) 2014-04-23
US7132098B2 (en) 2006-11-07
ES2389555T3 (es) 2012-10-29
JP4620868B2 (ja) 2011-01-26
AU2004202345A1 (en) 2004-06-24
DE69933686D1 (de) 2006-11-30
DE69927512T2 (de) 2006-07-06
EP1119611A4 (de) 2004-12-01
EP1119611A1 (de) 2001-08-01
JP2015126921A (ja) 2015-07-09
WO2000020559A1 (en) 2000-04-13
AU772479B2 (en) 2004-04-29
CA2343698C (en) 2014-05-20
JP2013075173A (ja) 2013-04-25
US20040033221A1 (en) 2004-02-19
EP1117422B1 (de) 2005-09-28
ATE342961T1 (de) 2006-11-15
WO2000020021A1 (en) 2000-04-13
ES2478257T3 (es) 2014-07-21
AU5241799A (en) 2000-04-26
DE69933686T2 (de) 2007-08-23
CA2346375C (en) 2013-04-23
JP2002526553A (ja) 2002-08-20
EP2374870A3 (de) 2012-03-14
JP2010137085A (ja) 2010-06-24
AU5330199A (en) 2000-04-26
JP4768125B2 (ja) 2011-09-07
AU770725B2 (en) 2004-02-26
US20020106362A1 (en) 2002-08-08
JP5623764B2 (ja) 2014-11-12
CA2343698A1 (en) 2000-04-13

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