ATE342961T1 - Zusammensetzung zur verwendung in der chemonukleolyse - Google Patents

Zusammensetzung zur verwendung in der chemonukleolyse

Info

Publication number
ATE342961T1
ATE342961T1 AT99938920T AT99938920T ATE342961T1 AT E342961 T1 ATE342961 T1 AT E342961T1 AT 99938920 T AT99938920 T AT 99938920T AT 99938920 T AT99938920 T AT 99938920T AT E342961 T1 ATE342961 T1 AT E342961T1
Authority
AT
Austria
Prior art keywords
tissues
methods
devices
chemonucleolysis
composition
Prior art date
Application number
AT99938920T
Other languages
English (en)
Inventor
Koichi Masuda
Eugene J-M A Thonar
Howard An
Kuber T Sampath
Original Assignee
Univ Rush Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rush Medical Center filed Critical Univ Rush Medical Center
Application granted granted Critical
Publication of ATE342961T1 publication Critical patent/ATE342961T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Prostheses (AREA)
AT99938920T 1998-10-06 1999-07-30 Zusammensetzung zur verwendung in der chemonukleolyse ATE342961T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10316198P 1998-10-06 1998-10-06

Publications (1)

Publication Number Publication Date
ATE342961T1 true ATE342961T1 (de) 2006-11-15

Family

ID=22293705

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99938920T ATE342961T1 (de) 1998-10-06 1999-07-30 Zusammensetzung zur verwendung in der chemonukleolyse
AT99937624T ATE305310T1 (de) 1998-10-06 1999-07-30 Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99937624T ATE305310T1 (de) 1998-10-06 1999-07-30 Verwendung von op-1 zur herstellung einer pharmazeutischen zusammensetzung zur reparatur von nicht-gelenksknorpeldefekten eines säugers

Country Status (10)

Country Link
US (2) US20020106362A1 (de)
EP (3) EP1117422B1 (de)
JP (5) JP4768125B2 (de)
AT (2) ATE342961T1 (de)
AU (3) AU770725B2 (de)
CA (2) CA2346375C (de)
DE (2) DE69933686T2 (de)
ES (2) ES2389555T3 (de)
MX (1) MXPA01003538A (de)
WO (2) WO2000020021A1 (de)

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US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US20030153976A1 (en) 1999-10-20 2003-08-14 Cauthen Joseph C. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20020032155A1 (en) * 2000-06-30 2002-03-14 Ferree Bret A. Method of treating disc herniation and disc degeneration with concentrated growth and differentiation factors
WO2003000287A1 (fr) * 2001-06-26 2003-01-03 Komori, Hiromichi Traitement d'une hernie
HUP0500634A3 (en) * 2001-08-13 2006-03-28 Univ Florida Materials and methods to promote repair of nerve tissue
GB0205022D0 (en) * 2002-03-04 2002-04-17 Univ Cambridge Tech Materials and methods for the treatment of cns damage
US6812211B2 (en) 2002-03-19 2004-11-02 Michael Andrew Slivka Method for nonsurgical treatment of the intervertebral disc and kit therefor
EP1575548B1 (de) 2002-05-04 2011-03-09 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
WO2004017044A2 (en) * 2002-08-15 2004-02-26 Acorda Therapeutics, Inc. Chimeric protein
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ES2373039T3 (es) * 2003-05-16 2012-01-30 Acorda Therapeutics, Inc. Composiciones y métodos para el tratamiento de lesiones del cns.
AU2004247026B2 (en) * 2003-05-16 2009-09-24 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of CNS
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US8226941B2 (en) * 2004-05-18 2012-07-24 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
CA2567405A1 (en) * 2004-05-25 2005-12-08 Stryker Corporation Use of morphogenic proteins for treating cartilage defects
AU2011265308B2 (en) * 2004-05-25 2014-06-26 Stryker Corporation Use of Morphogenic Proteins for Treating Cartilage Defects
US20060194726A1 (en) * 2004-05-25 2006-08-31 Rueger David C Methods of treating cartilage defects
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
FR2884437B1 (fr) * 2005-04-19 2007-07-20 Commissariat Energie Atomique Dispositif et procede microfluidique de transfert de matiere entre deux phases immiscibles.
JP4907908B2 (ja) * 2005-06-29 2012-04-04 ルネサスエレクトロニクス株式会社 駆動回路及び表示装置
WO2007038548A2 (en) * 2005-09-26 2007-04-05 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
JP4599563B2 (ja) * 2005-11-04 2010-12-15 国立大学法人 岡山大学 外耳道再建用成形品及びその製造方法
US20070213717A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Biological fusion in the vertebral column
US20070213718A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070213822A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070227547A1 (en) * 2006-02-14 2007-10-04 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070258941A1 (en) * 2006-05-02 2007-11-08 Pfister Brian E Methods and compositions for remediation of disc herniation by modifying structure
US20080027554A1 (en) * 2006-07-31 2008-01-31 Talmadge Karen D Kit and methods of treatment of an intervertebral disc
EP2450442B1 (de) 2006-10-10 2017-07-19 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur verwendung von chondroitinase-abci-mutanten
US20090286289A1 (en) * 2008-03-10 2009-11-19 Pang Danny Z Production of Hyaluronate Unsaturated Disaccharides and its Application
WO2010003016A2 (en) * 2008-07-04 2010-01-07 Axial Biotech, Inc Genetic markers associated with degenerative disc disease and uses thereof
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20120122791A1 (en) * 2009-05-01 2012-05-17 Jnc Corporation Substrate for cartilage cultivation using artificial collagen, and method for cartilage regeneration treatment using the substrate
JP2013513428A (ja) 2009-12-13 2013-04-22 アミット プラカシュ ゴヴィル 生体活性のある移植片およびコンポジット
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US9414930B2 (en) 2010-10-26 2016-08-16 Kyphon SÀRL Activatable devices containing a chemonucleolysis agent
WO2012058267A2 (en) * 2010-10-26 2012-05-03 Kyphon Sarl Devices containing a chemonucleolysis agent and methods for treating an intervertebral disc or spinal arachnoiditis
US8740982B2 (en) * 2010-10-26 2014-06-03 Kyphon Sarl Devices containing a chemonucleolysis agent and methods for treating an intervertebral disc or spinal arachnoiditis
US8404268B2 (en) 2010-10-26 2013-03-26 Kyphon Sarl Locally targeted anti-fibrotic agents and methods of use
CN111265472A (zh) * 2010-12-13 2020-06-12 生化学工业株式会社 椎间盘突出治疗剂
US8460381B2 (en) 2011-03-31 2013-06-11 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs disorders
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
US10179012B2 (en) 2013-01-28 2019-01-15 Cartiva, Inc. Systems and methods for orthopedic repair
US10493247B2 (en) 2016-03-15 2019-12-03 Medtronic Holding Company Sàrl Devices for delivering a chemical denervation agent and methods of use
CN113388599B (zh) * 2021-04-22 2022-10-28 浙江大学 用于分散生物组织的酶试剂盒和使用其获得单细胞悬液的方法

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Also Published As

Publication number Publication date
JP2010137085A (ja) 2010-06-24
AU2004202345A1 (en) 2004-06-24
AU770725B2 (en) 2004-02-26
CA2346375C (en) 2013-04-23
DE69933686D1 (de) 2006-11-30
ATE305310T1 (de) 2005-10-15
EP1119611A1 (de) 2001-08-01
CA2343698C (en) 2014-05-20
JP2013075173A (ja) 2013-04-25
JP4620868B2 (ja) 2011-01-26
EP2374870A2 (de) 2011-10-12
US7132098B2 (en) 2006-11-07
CA2343698A1 (en) 2000-04-13
JP2002526553A (ja) 2002-08-20
ES2389555T3 (es) 2012-10-29
AU5330199A (en) 2000-04-26
JP5623764B2 (ja) 2014-11-12
JP2015126921A (ja) 2015-07-09
WO2000020559A1 (en) 2000-04-13
US20020106362A1 (en) 2002-08-08
EP1119611B1 (de) 2006-10-18
AU5241799A (en) 2000-04-26
US20040033221A1 (en) 2004-02-19
AU772479B2 (en) 2004-04-29
AU2004202345B2 (en) 2007-12-13
ES2478257T3 (es) 2014-07-21
CA2346375A1 (en) 2000-04-13
EP2374870B1 (de) 2014-04-23
JP2002526167A (ja) 2002-08-20
WO2000020021A1 (en) 2000-04-13
DE69927512T2 (de) 2006-07-06
EP1117422A1 (de) 2001-07-25
EP1119611A4 (de) 2004-12-01
MXPA01003538A (es) 2005-09-08
DE69933686T2 (de) 2007-08-23
JP4768125B2 (ja) 2011-09-07
EP1117422B1 (de) 2005-09-28
DE69927512D1 (de) 2006-02-09
EP2374870A3 (de) 2012-03-14

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