DE69923974D1 - Koagulierungskontrolle für pt- und aptt-tests - Google Patents
Koagulierungskontrolle für pt- und aptt-testsInfo
- Publication number
- DE69923974D1 DE69923974D1 DE69923974T DE69923974T DE69923974D1 DE 69923974 D1 DE69923974 D1 DE 69923974D1 DE 69923974 T DE69923974 T DE 69923974T DE 69923974 T DE69923974 T DE 69923974T DE 69923974 D1 DE69923974 D1 DE 69923974D1
- Authority
- DE
- Germany
- Prior art keywords
- plasma
- heparin
- anticoagulant
- coagulation control
- factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000015271 coagulation Effects 0.000 title abstract 4
- 238000005345 coagulation Methods 0.000 title abstract 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 3
- 241000288906 Primates Species 0.000 abstract 3
- 239000003146 anticoagulant agent Substances 0.000 abstract 3
- 229940127219 anticoagulant drug Drugs 0.000 abstract 3
- 102000004411 Antithrombin III Human genes 0.000 abstract 2
- 108090000935 Antithrombin III Proteins 0.000 abstract 2
- 102000004032 Heparin Cofactor II Human genes 0.000 abstract 2
- 108090000481 Heparin Cofactor II Proteins 0.000 abstract 2
- 229960005348 antithrombin iii Drugs 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 239000002628 heparin derivative Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 abstract 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 229920002683 Glycosaminoglycan Polymers 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003114 blood coagulation factor Substances 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2496/00—Reference solutions for assays of biological material
- G01N2496/05—Reference solutions for assays of biological material containing blood cells or plasma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US108732 | 1979-12-31 | ||
| US09/108,732 US6194394B1 (en) | 1998-07-01 | 1998-07-01 | Coagulation controls for prothrombin time (PT) and activated partial thromboplastin time (APTT) assays |
| PCT/US1999/013974 WO2000002054A1 (en) | 1998-07-01 | 1999-06-21 | Coagulation controls for pt and aptt assays |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69923974D1 true DE69923974D1 (de) | 2005-04-07 |
| DE69923974T2 DE69923974T2 (de) | 2005-07-21 |
Family
ID=22323751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69923974T Expired - Fee Related DE69923974T2 (de) | 1998-07-01 | 1999-06-21 | Koagulierungskontrolle für pt- und aptt-tests |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6194394B1 (de) |
| EP (1) | EP1092157B1 (de) |
| JP (1) | JP2002519703A (de) |
| AT (1) | ATE290216T1 (de) |
| AU (1) | AU742965B2 (de) |
| CA (1) | CA2334582C (de) |
| DE (1) | DE69923974T2 (de) |
| ES (1) | ES2237114T3 (de) |
| WO (1) | WO2000002054A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU744025B2 (en) * | 1997-12-09 | 2002-02-14 | Sigma-Aldrich Co. | Plasma reference |
| US6541262B1 (en) | 2000-04-28 | 2003-04-01 | Medtronic, Inc. | Method and device for testing a sample of fresh whole blood |
| US6682933B2 (en) * | 2002-03-14 | 2004-01-27 | Lifescan, Inc. | Test strip qualification system |
| US6673617B2 (en) | 2002-03-14 | 2004-01-06 | Lifescan, Inc. | Test strip qualification system |
| US7358337B2 (en) * | 2002-08-16 | 2008-04-15 | International Technidyne Corporation | Assay for low molecular weight heparin |
| US7247488B2 (en) * | 2003-05-06 | 2007-07-24 | Medtronic, Inc. | Method and kit for testing a multi-channel blood assay cartridge |
| CA2525940A1 (en) * | 2003-05-16 | 2004-11-25 | National Institute For Biological Standards And Control (Nibsc) | Mixture |
| WO2005111231A2 (en) * | 2004-05-11 | 2005-11-24 | Heptest Laboratories, Inc. | Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| CN101151533A (zh) * | 2005-02-16 | 2008-03-26 | 伊利诺斯大学理事会 | 基于金属螯合脂质的促凝血剂 |
| DE602006021290D1 (de) * | 2005-03-04 | 2011-05-26 | Univ Illinois | Modulator von coagulationskaskaden und fibrinolytischen kaskaden |
| DE102005028018A1 (de) * | 2005-06-16 | 2006-12-21 | Dade Behring Marburg Gmbh | Verfahren zur Standardisierung von Gerinnungstesten |
| FR2922024B1 (fr) | 2007-10-04 | 2011-03-25 | Stago Diagnostica | Methode d'ajustement de la calibration de tests diagnostiques |
| WO2009046194A2 (en) * | 2007-10-05 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Fibrin sealant |
| WO2009061697A1 (en) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| FR2933496B1 (fr) * | 2008-07-02 | 2012-10-05 | Lfb Biotechnologies | Procede de mesure du taux de facteur vii active dans un echantillon |
| IS2809B (is) | 2011-03-08 | 2012-10-15 | Haskoli Islands | Blóðstorkumæling |
| US9354144B2 (en) | 2011-09-20 | 2016-05-31 | Bio-Rad Laboratories, Inc. | Customized quality controls for analytical assays |
| EP2834635A4 (de) | 2012-04-03 | 2015-09-02 | Smiths Medical Asd Inc | Zusammensetzungen mit einem heparinakkumulationsmittel und verfahren dafür |
| CN103376329A (zh) * | 2012-04-19 | 2013-10-30 | 蓬莱诺康药业有限公司 | 巴曲亭及其有效成份止血作用的表征方法 |
| WO2014205426A1 (en) * | 2013-06-21 | 2014-12-24 | Imigene, Inc. | Blood analysis |
| AU2014384759B2 (en) * | 2014-02-28 | 2021-07-22 | Nitto Denko Corporation | Urinalysis device and dry reagent for quantitative urinalysis |
| ES2475492B1 (es) * | 2014-03-13 | 2015-01-15 | Grifols Worldwide Operations Limited | Composición para su utilización como plasma de control anormal de la coagulación en ensayos in vitro |
| ES2671844B1 (es) | 2015-06-11 | 2019-03-22 | Attwill Medical Solutions Inc | Dispositivos médicos, sistemas y métodos que utilizan composiciones de anti-trombina heparina. |
| CN111295094A (zh) | 2017-10-09 | 2020-06-16 | 泰尔茂比司特生物技术有限公司 | 冻干容器及使用冻干容器的方法 |
| JP2022525742A (ja) | 2019-03-14 | 2022-05-19 | テルモ ビーシーティー バイオテクノロジーズ，エルエルシー | 凍結乾燥用ローディングトレイ組立体及びシステム |
| EP4314819A1 (de) * | 2021-03-31 | 2024-02-07 | Haemonetics Corporation | Qualitätskontrollformulierungen für hämostasemessvorrichtung |
| CN117741166B (zh) * | 2024-02-19 | 2024-04-26 | 北京水木济衡生物技术有限公司 | 一种多项目复合凝血质控品及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947378A (en) | 1974-12-23 | 1976-03-30 | Warner-Lambert Company | Adsorbed plasma |
| DE2461969A1 (de) | 1974-12-31 | 1976-07-08 | Behringwerke Ag | Stabiles blutplasma, verfahren zu dessen herstellung und seine verwendung als vergleichsplasma bei gerinnungs- untersuchungen |
| US4007008A (en) | 1975-07-30 | 1977-02-08 | Becker Milton J | Preparation of reference serum from animal blood |
| US4116635A (en) | 1977-03-14 | 1978-09-26 | Jaeger Mark A | General purpose in vitro anticoagulant |
| US4127502A (en) | 1977-06-10 | 1978-11-28 | Eastman Kodak Company | Stabilizers for reconstituted, lyophilized samples |
| DE2903701C2 (de) | 1979-01-31 | 1980-10-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | Kontrollreagens für die Bestimmung der Heparinaktivität |
| US4543335A (en) * | 1982-12-20 | 1985-09-24 | Miles Laboratories, Inc. | Device and method for the quantitative determination of heparin in mammalian blood plasma |
| US4948724A (en) * | 1985-09-05 | 1990-08-14 | Yin E Thye | Composition, kit and method for assaying heparin and a method for making the composition |
| US5017556A (en) | 1986-11-04 | 1991-05-21 | Genentech, Inc. | Treatment of bleeding disorders using lipid-free tissue factor protein |
| US5221614A (en) * | 1988-03-03 | 1993-06-22 | Nippon Shoji Kabushiki Kaisha | Method and reagent for determining the biological activity of antithrombin III by measuring coagulation time |
| US5138034A (en) * | 1989-07-12 | 1992-08-11 | The Green Cross Corporation | Method of fractionating plasma proteins |
| EP0482088B1 (de) * | 1989-07-20 | 1999-03-31 | Analytical Control Systems, Inc. | Verbesserte kontrollverfahren für stabile blutkoagulation |
| US5169786A (en) * | 1989-12-19 | 1992-12-08 | Ortho Diagnostic Systems, Inc. | Method of determining levels of extrinsic and intrinsic clotting factors and protein c |
| EP0509086B1 (de) * | 1990-11-05 | 1995-04-12 | Dade Produktions AG | Verfahren zur bestimmung der konzentration von antikoagulantien |
| US5308755A (en) * | 1992-06-08 | 1994-05-03 | Research Corporation Technologies, Inc. | Method for measuring heparin |
-
1998
- 1998-07-01 US US09/108,732 patent/US6194394B1/en not_active Expired - Lifetime
-
1999
- 1999-06-21 DE DE69923974T patent/DE69923974T2/de not_active Expired - Fee Related
- 1999-06-21 WO PCT/US1999/013974 patent/WO2000002054A1/en active IP Right Grant
- 1999-06-21 JP JP2000558398A patent/JP2002519703A/ja active Pending
- 1999-06-21 AU AU45807/99A patent/AU742965B2/en not_active Ceased
- 1999-06-21 CA CA002334582A patent/CA2334582C/en not_active Expired - Fee Related
- 1999-06-21 AT AT99928825T patent/ATE290216T1/de not_active IP Right Cessation
- 1999-06-21 EP EP99928825A patent/EP1092157B1/de not_active Expired - Lifetime
- 1999-06-21 ES ES99928825T patent/ES2237114T3/es not_active Expired - Lifetime
-
2001
- 2001-01-26 US US09/771,195 patent/US6528273B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1092157B1 (de) | 2005-03-02 |
| ES2237114T3 (es) | 2005-07-16 |
| JP2002519703A (ja) | 2002-07-02 |
| AU742965B2 (en) | 2002-01-17 |
| CA2334582A1 (en) | 2000-01-13 |
| DE69923974T2 (de) | 2005-07-21 |
| US6528273B2 (en) | 2003-03-04 |
| WO2000002054A1 (en) | 2000-01-13 |
| EP1092157A1 (de) | 2001-04-18 |
| AU4580799A (en) | 2000-01-24 |
| US6194394B1 (en) | 2001-02-27 |
| CA2334582C (en) | 2002-12-10 |
| US20010004641A1 (en) | 2001-06-21 |
| ATE290216T1 (de) | 2005-03-15 |
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|---|---|---|
| DE69923974D1 (de) | Koagulierungskontrolle für pt- und aptt-tests | |
| Nagase et al. | Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III-and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |