DE69922642T2 - Virale chimären aus caev und hiv-1 genetischen elementen - Google Patents

Virale chimären aus caev und hiv-1 genetischen elementen Download PDF

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Publication number
DE69922642T2
DE69922642T2 DE69922642T DE69922642T DE69922642T2 DE 69922642 T2 DE69922642 T2 DE 69922642T2 DE 69922642 T DE69922642 T DE 69922642T DE 69922642 T DE69922642 T DE 69922642T DE 69922642 T2 DE69922642 T2 DE 69922642T2
Authority
DE
Germany
Prior art keywords
hiv
chiv
caev
virus
immunogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69922642T
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German (de)
English (en)
Other versions
DE69922642D1 (de
Inventor
Angeline Douvas
B. Tyler PARR
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by University of Southern California USC filed Critical University of Southern California USC
Publication of DE69922642D1 publication Critical patent/DE69922642D1/de
Application granted granted Critical
Publication of DE69922642T2 publication Critical patent/DE69922642T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16041Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69922642T 1998-04-30 1999-04-30 Virale chimären aus caev und hiv-1 genetischen elementen Expired - Lifetime DE69922642T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US302171 1989-01-30
US8365298P 1998-04-30 1998-04-30
US83652P 1998-04-30
US09/302,171 US6602505B2 (en) 1998-04-30 1999-04-29 Viral chimeras comprised of CAEV and HIV-1 genetic elements
PCT/US1999/006556 WO1999056774A1 (en) 1998-04-30 1999-04-30 Viral chimeras comprised of caev and hiv-1 genetic elements

Publications (2)

Publication Number Publication Date
DE69922642D1 DE69922642D1 (de) 2005-01-20
DE69922642T2 true DE69922642T2 (de) 2005-12-22

Family

ID=26769556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69922642T Expired - Lifetime DE69922642T2 (de) 1998-04-30 1999-04-30 Virale chimären aus caev und hiv-1 genetischen elementen

Country Status (12)

Country Link
US (1) US6602505B2 (enExample)
EP (1) EP1073461B1 (enExample)
JP (1) JP2002513546A (enExample)
KR (1) KR20010074495A (enExample)
CN (1) CN100346827C (enExample)
AT (1) ATE284709T1 (enExample)
AU (1) AU766264B2 (enExample)
CA (1) CA2330618C (enExample)
DE (1) DE69922642T2 (enExample)
IL (2) IL139360A0 (enExample)
NZ (1) NZ507942A (enExample)
WO (1) WO1999056774A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6361784B1 (en) * 2000-09-29 2002-03-26 The Procter & Gamble Company Soft, flexible disposable wipe with embossing
FR2979919B1 (fr) * 2011-09-12 2015-12-11 Centre Nat Rech Scient Genomes lentiviraux chimeriques non-integratifs comme vaccins innovants contre vih-1
WO2013126469A1 (en) * 2012-02-21 2013-08-29 Immunogenetix Therapeutics, Inc. Chimeric dna vaccine compositions and methods of use
RU2017126206A (ru) * 2014-12-23 2019-01-25 Маргарет Анне БРИМБЛЕ Аминокислотные и пептидные конъюгаты и направления их использования
AU2017223267B2 (en) 2016-02-26 2021-07-22 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142025A (en) 1986-08-01 1992-08-25 Repligen Corporation Recombinant HTLV-III proteins and uses thereof
US5256767A (en) 1987-06-10 1993-10-26 The Immune Response Corporation Retroviral antigens
US5716826A (en) 1988-03-21 1998-02-10 Chiron Viagene, Inc. Recombinant retroviruses
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5851813A (en) 1990-07-12 1998-12-22 President And Fellows Of Harvard College Primate lentivirus antigenic compositions
US5714374A (en) 1990-09-12 1998-02-03 Rutgers University Chimeric rhinoviruses
US5770428A (en) 1993-02-17 1998-06-23 Wisconsin Alumni Research Foundation Chimeric retrovial expression vectors and particles containing a simple retroviral long terminal repeat, BLV or HIV coding regions and cis-acting regulatory sequences, and an RNA translational enhancer with internal ribsome entry site
US5561064A (en) 1994-02-01 1996-10-01 Vical Incorporated Production of pharmaceutical-grade plasmid DNA
FR2721618B1 (fr) 1994-06-28 1996-09-13 Centre Nat Rech Scient Fragments d'acide nucléique et fragments peptidiques correspondants issus du génome du virus de l'arthrite et de l'encéphalite caprine (VAEC) et leurs applications.
US5955342A (en) 1994-08-15 1999-09-21 Connaught Laboratories Limited Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region
FR2732346B1 (fr) 1995-03-27 1997-05-30 Centre Nat Rech Scient Proteines mutees, codees par un gene env mute de lentivirus, fragments peptidiques inclus dans lesdites proteines, vecteurs d'expression exprimant lesdites proteines mutees et leurs applications
DE69707680T2 (de) 1996-03-15 2002-07-11 University Of Southern California, Los Angeles Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv-1 infektion
US5770357A (en) 1996-03-15 1998-06-23 Univ Southern California Method of diagnosing caprine arthritis-encephalitis virus infection
EP1012236A1 (en) * 1997-08-15 2000-06-28 Rubicon Laboratory Inc. Retrovirus and viral vectors

Also Published As

Publication number Publication date
ATE284709T1 (de) 2005-01-15
US20010039669A1 (en) 2001-11-08
KR20010074495A (ko) 2001-08-04
EP1073461A1 (en) 2001-02-07
JP2002513546A (ja) 2002-05-14
NZ507942A (en) 2003-06-30
EP1073461B1 (en) 2004-12-15
WO1999056774A1 (en) 1999-11-11
CA2330618A1 (en) 1999-11-11
CN1311689A (zh) 2001-09-05
DE69922642D1 (de) 2005-01-20
US6602505B2 (en) 2003-08-05
IL139360A0 (en) 2001-11-25
AU766264B2 (en) 2003-10-09
EP1073461A4 (en) 2002-03-20
CA2330618C (en) 2012-07-03
IL139360A (en) 2007-07-24
AU3740699A (en) 1999-11-23
CN100346827C (zh) 2007-11-07

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