CN100346827C - 由caev和hiv－1遗传元件组成的病毒嵌合体 - Google Patents

由caev和hiv－1遗传元件组成的病毒嵌合体 Download PDF

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Publication number
CN100346827C
CN100346827C CNB99807912XA CN99807912A CN100346827C CN 100346827 C CN100346827 C CN 100346827C CN B99807912X A CNB99807912X A CN B99807912XA CN 99807912 A CN99807912 A CN 99807912A CN 100346827 C CN100346827 C CN 100346827C
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CN
China
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hiv
chiv
caev
virus
chimeric
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Expired - Fee Related
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CNB99807912XA
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English (en)
Chinese (zh)
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CN1311689A (zh
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安杰莱恩·道瓦斯
泰勒·B·帕尔
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University of Southern California USC
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University of Southern California USC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CNB99807912XA 1998-04-30 1999-04-30 由caev和hiv－1遗传元件组成的病毒嵌合体 Expired - Fee Related CN100346827C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8365298P 1998-04-30 1998-04-30
US60/083,652 1998-04-30
US09/302,171 1999-04-29
US09/302,171 US6602505B2 (en) 1998-04-30 1999-04-29 Viral chimeras comprised of CAEV and HIV-1 genetic elements

Publications (2)

Publication Number Publication Date
CN1311689A CN1311689A (zh) 2001-09-05
CN100346827C true CN100346827C (zh) 2007-11-07

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ID=26769556

Family Applications (1)

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CNB99807912XA Expired - Fee Related CN100346827C (zh) 1998-04-30 1999-04-30 由caev和hiv－1遗传元件组成的病毒嵌合体

Country Status (12)

Country Link
US (1) US6602505B2 (enExample)
EP (1) EP1073461B1 (enExample)
JP (1) JP2002513546A (enExample)
KR (1) KR20010074495A (enExample)
CN (1) CN100346827C (enExample)
AT (1) ATE284709T1 (enExample)
AU (1) AU766264B2 (enExample)
CA (1) CA2330618C (enExample)
DE (1) DE69922642T2 (enExample)
IL (2) IL139360A0 (enExample)
NZ (1) NZ507942A (enExample)
WO (1) WO1999056774A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6361784B1 (en) * 2000-09-29 2002-03-26 The Procter & Gamble Company Soft, flexible disposable wipe with embossing
FR2979919B1 (fr) * 2011-09-12 2015-12-11 Centre Nat Rech Scient Genomes lentiviraux chimeriques non-integratifs comme vaccins innovants contre vih-1
US20130337009A1 (en) * 2012-02-21 2013-12-19 Immunogenetix Therapeutics, Inc. Chimeric dna vaccine compositions and methods of use
CA2971677A1 (en) * 2014-12-23 2016-06-30 Margaret Anne Brimble Amino acid and peptide conjugates and uses thereof
WO2017145097A2 (en) 2016-02-26 2017-08-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142025A (en) * 1986-08-01 1992-08-25 Repligen Corporation Recombinant HTLV-III proteins and uses thereof
US5714374A (en) * 1990-09-12 1998-02-03 Rutgers University Chimeric rhinoviruses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256767A (en) 1987-06-10 1993-10-26 The Immune Response Corporation Retroviral antigens
US5716826A (en) 1988-03-21 1998-02-10 Chiron Viagene, Inc. Recombinant retroviruses
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5851813A (en) 1990-07-12 1998-12-22 President And Fellows Of Harvard College Primate lentivirus antigenic compositions
US5770428A (en) 1993-02-17 1998-06-23 Wisconsin Alumni Research Foundation Chimeric retrovial expression vectors and particles containing a simple retroviral long terminal repeat, BLV or HIV coding regions and cis-acting regulatory sequences, and an RNA translational enhancer with internal ribsome entry site
US5561064A (en) 1994-02-01 1996-10-01 Vical Incorporated Production of pharmaceutical-grade plasmid DNA
FR2721618B1 (fr) 1994-06-28 1996-09-13 Centre Nat Rech Scient Fragments d'acide nucléique et fragments peptidiques correspondants issus du génome du virus de l'arthrite et de l'encéphalite caprine (VAEC) et leurs applications.
US5955342A (en) 1994-08-15 1999-09-21 Connaught Laboratories Limited Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region
FR2732346B1 (fr) 1995-03-27 1997-05-30 Centre Nat Rech Scient Proteines mutees, codees par un gene env mute de lentivirus, fragments peptidiques inclus dans lesdites proteines, vecteurs d'expression exprimant lesdites proteines mutees et leurs applications
US5770357A (en) 1996-03-15 1998-06-23 Univ Southern California Method of diagnosing caprine arthritis-encephalitis virus infection
JP2002503205A (ja) 1996-03-15 2002-01-29 ユニバーシティ オブ サザン カリフォルニア ヤギ関節炎―脳炎ウイルスは、ｈｉｖ―１感染に対して免疫防御を提供する
WO1999009139A1 (en) * 1997-08-15 1999-02-25 Rubicon Laboratory, Inc. Retrovirus and viral vectors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142025A (en) * 1986-08-01 1992-08-25 Repligen Corporation Recombinant HTLV-III proteins and uses thereof
US5714374A (en) * 1990-09-12 1998-02-03 Rutgers University Chimeric rhinoviruses

Also Published As

Publication number Publication date
US20010039669A1 (en) 2001-11-08
DE69922642D1 (de) 2005-01-20
CA2330618C (en) 2012-07-03
CA2330618A1 (en) 1999-11-11
DE69922642T2 (de) 2005-12-22
ATE284709T1 (de) 2005-01-15
US6602505B2 (en) 2003-08-05
JP2002513546A (ja) 2002-05-14
EP1073461A4 (en) 2002-03-20
CN1311689A (zh) 2001-09-05
AU3740699A (en) 1999-11-23
NZ507942A (en) 2003-06-30
IL139360A (en) 2007-07-24
EP1073461A1 (en) 2001-02-07
IL139360A0 (en) 2001-11-25
WO1999056774A1 (en) 1999-11-11
KR20010074495A (ko) 2001-08-04
AU766264B2 (en) 2003-10-09
EP1073461B1 (en) 2004-12-15

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Granted publication date: 20071107

Termination date: 20140430