DE69922024T2 - Pyrrolochinoline zur Behandlung von Fettleibigkeit - Google Patents
Pyrrolochinoline zur Behandlung von Fettleibigkeit Download PDFInfo
- Publication number
- DE69922024T2 DE69922024T2 DE69922024T DE69922024T DE69922024T2 DE 69922024 T2 DE69922024 T2 DE 69922024T2 DE 69922024 T DE69922024 T DE 69922024T DE 69922024 T DE69922024 T DE 69922024T DE 69922024 T2 DE69922024 T2 DE 69922024T2
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- Germany
- Prior art keywords
- compound according
- disorders
- hydrogen
- alkyl
- pyrrolo
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9819019.2A GB9819019D0 (en) | 1998-09-01 | 1998-09-01 | Chemical compounds II |
| GB9819019 | 1998-09-01 | ||
| PCT/GB1999/002887 WO2000012502A1 (en) | 1998-09-01 | 1999-09-01 | Pyrroloquinolines for treatment of obesity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69922024D1 DE69922024D1 (de) | 2004-12-23 |
| DE69922024T2 true DE69922024T2 (de) | 2005-09-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69922024T Expired - Fee Related DE69922024T2 (de) | 1998-09-01 | 1999-09-01 | Pyrrolochinoline zur Behandlung von Fettleibigkeit |
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| US (1) | US6365598B1 (enExample) |
| EP (1) | EP1109809B1 (enExample) |
| JP (1) | JP2002523506A (enExample) |
| AT (1) | ATE282613T1 (enExample) |
| AU (1) | AU5637799A (enExample) |
| CA (1) | CA2341986A1 (enExample) |
| DE (1) | DE69922024T2 (enExample) |
| DK (1) | DK1109809T3 (enExample) |
| ES (1) | ES2232168T3 (enExample) |
| GB (1) | GB9819019D0 (enExample) |
| PT (1) | PT1109809E (enExample) |
| WO (1) | WO2000012502A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB9902047D0 (en) * | 1999-01-29 | 1999-03-17 | Cerebrus Ltd | Chemical compounds XI |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| GB9918965D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxi |
| SE0004245D0 (sv) | 2000-11-20 | 2000-11-20 | Pharmacia Ab | Novel compounds and their use |
| DE60139021D1 (de) | 2000-11-20 | 2009-07-30 | Biovitrum Ab Publ | Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors |
| US7026484B2 (en) | 2001-02-23 | 2006-04-11 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
| US7214690B2 (en) | 2001-02-23 | 2007-05-08 | Ligand Pharmaceuticals Incorporated | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods |
| EP1513831B1 (en) | 2002-06-19 | 2010-01-06 | Biovitrum AB (publ) | Novel compounds, their use and preparation |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| CA2495192A1 (en) * | 2002-08-30 | 2004-03-11 | Alcon, Inc. | Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma |
| CL2004000826A1 (es) | 2003-04-25 | 2005-03-04 | Pfizer | Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129 |
| GB0314967D0 (en) | 2003-06-26 | 2003-07-30 | Hoffmann La Roche | Piperazine derivatives |
| EP2400300A1 (en) | 2004-08-25 | 2011-12-28 | Takeda Pharmaceutical Company Limited | Method of screening preventives/remedies for stress urinary incontinence |
| AP2007004144A0 (en) | 2005-03-31 | 2007-08-31 | Pfizer Prod Inc | Cyclopentapyridine and tetrahydroquinoline derivatives |
| WO2006138347A2 (en) | 2005-06-17 | 2006-12-28 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| WO2007053353A2 (en) * | 2005-10-28 | 2007-05-10 | Wyeth | Pyrrolo[2,3-f] and [3,2-f]isoquinolinone derivatives as 5-hydroxytryptamine-6 ligands |
| EP1991531A1 (en) * | 2006-02-28 | 2008-11-19 | Amgen Inc. | Cinnoline and quinoxaline derivates as phosphodiesterase 10 inhibitors |
| WO2007132841A1 (ja) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物およびその用途 |
| ATE496894T1 (de) * | 2006-07-14 | 2011-02-15 | Pfizer Prod Inc | Tartratsalz von (7s)-7-ä(5-fluor-2- |
| JP5520051B2 (ja) | 2007-11-15 | 2014-06-11 | 武田薬品工業株式会社 | 縮合ピリジン誘導体およびその用途 |
| KR101062376B1 (ko) | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| JPWO2011071136A1 (ja) | 2009-12-11 | 2013-04-22 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
| WO2015012704A1 (en) * | 2013-07-25 | 2015-01-29 | Uniwersytet Jagielloński | Pyrroloquinoline derivatives as 5-ht6 antagonists, preparation method and use thereof |
| WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
| US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW334423B (en) * | 1993-10-22 | 1998-06-21 | Hoffmann La Roche | Tricyclic 1-aminoethylpyrrole-derivatives |
| TW270114B (enExample) * | 1993-10-22 | 1996-02-11 | Hoffmann La Roche | |
| TW403738B (en) * | 1994-08-12 | 2000-09-01 | Hoffmann La Roche | Tricyclic pyrazole derivatives |
| AU5343298A (en) | 1997-01-13 | 1998-08-03 | Yamanouchi Pharmaceutical Co., Ltd. | 5-ht2c receptor agonists and aminoalkylindazole derivatives |
| AU727654B2 (en) * | 1997-06-13 | 2000-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Tricyclic pyrazole derivative |
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1998
- 1998-09-01 GB GBGB9819019.2A patent/GB9819019D0/en not_active Ceased
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1999
- 1999-09-01 AU AU56377/99A patent/AU5637799A/en not_active Abandoned
- 1999-09-01 WO PCT/GB1999/002887 patent/WO2000012502A1/en not_active Ceased
- 1999-09-01 CA CA002341986A patent/CA2341986A1/en not_active Abandoned
- 1999-09-01 DE DE69922024T patent/DE69922024T2/de not_active Expired - Fee Related
- 1999-09-01 PT PT99943093T patent/PT1109809E/pt unknown
- 1999-09-01 DK DK99943093T patent/DK1109809T3/da active
- 1999-09-01 AT AT99943093T patent/ATE282613T1/de not_active IP Right Cessation
- 1999-09-01 EP EP99943093A patent/EP1109809B1/en not_active Expired - Lifetime
- 1999-09-01 JP JP2000567530A patent/JP2002523506A/ja active Pending
- 1999-09-01 ES ES99943093T patent/ES2232168T3/es not_active Expired - Lifetime
- 1999-09-01 US US09/786,159 patent/US6365598B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6365598B1 (en) | 2002-04-02 |
| CA2341986A1 (en) | 2000-03-09 |
| EP1109809A1 (en) | 2001-06-27 |
| PT1109809E (pt) | 2005-02-28 |
| DE69922024D1 (de) | 2004-12-23 |
| JP2002523506A (ja) | 2002-07-30 |
| ES2232168T3 (es) | 2005-05-16 |
| AU5637799A (en) | 2000-03-21 |
| ATE282613T1 (de) | 2004-12-15 |
| EP1109809B1 (en) | 2004-11-17 |
| WO2000012502A1 (en) | 2000-03-09 |
| DK1109809T3 (da) | 2005-03-14 |
| GB9819019D0 (en) | 1998-10-28 |
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| 8339 | Ceased/non-payment of the annual fee |