DE69919535T2 - Flüssigkeitsstrahl- abscheidung von radioaktivem stoff für brachytherapie-vorrichtungen - Google Patents
Flüssigkeitsstrahl- abscheidung von radioaktivem stoff für brachytherapie-vorrichtungen Download PDFInfo
- Publication number
- DE69919535T2 DE69919535T2 DE69919535T DE69919535T DE69919535T2 DE 69919535 T2 DE69919535 T2 DE 69919535T2 DE 69919535 T DE69919535 T DE 69919535T DE 69919535 T DE69919535 T DE 69919535T DE 69919535 T2 DE69919535 T2 DE 69919535T2
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- Germany
- Prior art keywords
- radioactive
- fluid
- radiation
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002725 brachytherapy Methods 0.000 title claims description 69
- 239000007788 liquid Substances 0.000 title claims description 11
- 230000008021 deposition Effects 0.000 title description 3
- 239000000941 radioactive substance Substances 0.000 title 1
- 239000012530 fluid Substances 0.000 claims description 155
- 230000002285 radioactive effect Effects 0.000 claims description 99
- 230000005855 radiation Effects 0.000 claims description 87
- 239000012857 radioactive material Substances 0.000 claims description 87
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- 239000011630 iodine Substances 0.000 claims description 3
- 239000004115 Sodium Silicate Substances 0.000 claims description 2
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 2
- RUDFQVOCFDJEEF-UHFFFAOYSA-N yttrium(III) oxide Inorganic materials [O-2].[O-2].[O-2].[Y+3].[Y+3] RUDFQVOCFDJEEF-UHFFFAOYSA-N 0.000 claims description 2
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- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 9
- PNDPGZBMCMUPRI-XXSWNUTMSA-N [125I][125I] Chemical compound [125I][125I] PNDPGZBMCMUPRI-XXSWNUTMSA-N 0.000 description 9
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- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 3
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
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- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
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- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
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- 150000002334 glycols Chemical class 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
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- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229940044173 iodine-125 Drugs 0.000 description 1
- GKOZUEZYRPOHIO-IGMARMGPSA-N iridium-192 Chemical compound [192Ir] GKOZUEZYRPOHIO-IGMARMGPSA-N 0.000 description 1
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- PIBWKRNGBLPSSY-UHFFFAOYSA-L palladium(II) chloride Chemical compound Cl[Pd]Cl PIBWKRNGBLPSSY-UHFFFAOYSA-L 0.000 description 1
- YJVFFLUZDVXJQI-UHFFFAOYSA-L palladium(ii) acetate Chemical compound [Pd+2].CC([O-])=O.CC([O-])=O YJVFFLUZDVXJQI-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/085,357 US6086942A (en) | 1998-05-27 | 1998-05-27 | Fluid-jet deposition of radioactive material for brachytherapy devices |
| US85357 | 1998-05-27 | ||
| PCT/IB1999/000914 WO1999062074A1 (en) | 1998-05-27 | 1999-05-04 | Fluid-jet deposition of radioactive material for brachytherapy devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69919535D1 DE69919535D1 (de) | 2004-09-23 |
| DE69919535T2 true DE69919535T2 (de) | 2005-05-12 |
Family
ID=22191079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69919535T Expired - Lifetime DE69919535T2 (de) | 1998-05-27 | 1999-05-04 | Flüssigkeitsstrahl- abscheidung von radioaktivem stoff für brachytherapie-vorrichtungen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6086942A (enExample) |
| EP (1) | EP1082729B1 (enExample) |
| JP (1) | JP2002517006A (enExample) |
| CN (1) | CN1156857C (enExample) |
| AU (1) | AU3624799A (enExample) |
| BR (1) | BR9911202A (enExample) |
| CA (1) | CA2331421A1 (enExample) |
| DE (1) | DE69919535T2 (enExample) |
| WO (1) | WO1999062074A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60128463T2 (de) | 2000-04-28 | 2008-04-10 | Qsa Global Gmbh | Flutstrahlungsquelle und zugehöriges erzeugungsverfahren |
| WO2002027630A1 (en) * | 2000-09-28 | 2002-04-04 | Isostar Texas, Inc. | Fast photon counting assay system and method |
| WO2004026111A2 (en) | 2000-11-16 | 2004-04-01 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
| US6517890B2 (en) * | 2001-02-22 | 2003-02-11 | European Community | Thin layer preparation for radionuclide sources |
| US6623785B2 (en) * | 2001-06-07 | 2003-09-23 | Hewlett-Packard Development Company, L.P. | Pharmaceutical dispensing apparatus and method |
| US6723052B2 (en) * | 2001-06-07 | 2004-04-20 | Stanley L. Mills | Echogenic medical device |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| US6702894B2 (en) | 2001-10-24 | 2004-03-09 | Hewlett-Packard Development Company, L.P. | Fluid ejection cartridge and system for dispensing a bioactive substance |
| US6787786B2 (en) * | 2001-06-12 | 2004-09-07 | North American Scientific, Inc. | Thin radiation source and method of making the same |
| US7074291B2 (en) * | 2001-11-02 | 2006-07-11 | Worldwide Medical Technologies, L.L.C. | Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings |
| US7060020B2 (en) | 2001-11-02 | 2006-06-13 | Ideamatrix, Inc. | Delivery system and method for interstitial radiation therapy |
| US6786591B2 (en) | 2002-10-24 | 2004-09-07 | Hewlett-Packard Development Company, L.P. | Fluid ejector apparatus and methods |
| US20040081689A1 (en) * | 2002-10-24 | 2004-04-29 | Dunfield John Stephen | Pharmaceutical dosage form and method of making |
| EP1572029B1 (en) * | 2002-11-07 | 2010-03-24 | Abbott Laboratories | Method of loading beneficial agent to a prosthesis by fluid-jet application |
| US8221495B2 (en) | 2002-11-07 | 2012-07-17 | Abbott Laboratories | Integration of therapeutic agent into a bioerodible medical device |
| US8524148B2 (en) * | 2002-11-07 | 2013-09-03 | Abbott Laboratories | Method of integrating therapeutic agent into a bioerodible medical device |
| MXPA05007627A (es) * | 2003-01-17 | 2005-09-30 | Sicpa Holding Sa | Metodo, dispositivo y sistema para la marcacion temporal de objetos. |
| DE10306072B4 (de) * | 2003-02-13 | 2009-04-02 | Veritas Ag | Mehrschichtiger Schlauch |
| GB0305848D0 (en) * | 2003-03-14 | 2003-04-16 | Imaging Res Solutions Ltd | Radiopharmaceutical generation system |
| DE102004022200B4 (de) * | 2004-05-05 | 2006-07-20 | Actinium Pharmaceuticals, Inc. | Radium-Target sowie Verfahren zu seiner Herstellung |
| US8609198B2 (en) | 2004-07-21 | 2013-12-17 | Hewlett-Packard Development Company, L.P. | Pharmaceutical dose form with a patterned coating and method of making the same |
| US20060023843A1 (en) * | 2004-07-27 | 2006-02-02 | Kusch Jochen K | Cone-beam imaging for brachytherapy |
| US8187159B2 (en) | 2005-07-22 | 2012-05-29 | Biocompatibles, UK | Therapeutic member including a rail used in brachytherapy and other radiation therapy |
| US7736293B2 (en) * | 2005-07-22 | 2010-06-15 | Biocompatibles Uk Limited | Implants for use in brachytherapy and other radiation therapy that resist migration and rotation |
| DE102006008023B4 (de) * | 2006-02-21 | 2008-05-29 | Actinium Pharmaceuticals, Inc. | Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets |
| US7988611B2 (en) | 2006-05-09 | 2011-08-02 | Biocompatibles Uk Limited | After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy |
| US8679573B2 (en) * | 2006-06-28 | 2014-03-25 | Advanced Cardiovascular Systems, Inc. | Stent coating method and apparatus |
| US20090216063A1 (en) * | 2008-01-29 | 2009-08-27 | Biocompatibles Uk Limited | Bio-absorbable brachytherapy strands |
| WO2008027402A2 (en) * | 2006-08-29 | 2008-03-06 | Civatech Oncology | Brachytherapy devices and related methods and computer program products |
| US7878964B1 (en) | 2006-09-07 | 2011-02-01 | Biocompatibles Uk Limited | Echogenic spacers and strands |
| US7874976B1 (en) | 2006-09-07 | 2011-01-25 | Biocompatibles Uk Limited | Echogenic strands and spacers therein |
| CA2662932C (en) | 2006-09-08 | 2017-06-06 | Actinium Pharmaceuticals, Inc. | Method for the purification of radium from different sources |
| US8733274B2 (en) * | 2006-10-20 | 2014-05-27 | Hewlett-Packard Development Company, L.P. | Tube mounted inkjet printhead die |
| US7867548B2 (en) * | 2006-10-27 | 2011-01-11 | Hewlett-Packard Development Company, L.P. | Thermal ejection of solution having solute onto device medium |
| CA2760013C (en) * | 2008-05-02 | 2017-02-14 | Civatech Oncology | Brachytherapy devices and related methods and computer program products |
| US8253120B2 (en) * | 2008-07-31 | 2012-08-28 | Jason Short | Flood source with pigmentless active area and visible border |
| JP5441096B2 (ja) * | 2008-11-28 | 2014-03-12 | 独立行政法人日本原子力研究開発機構 | ラジオアイソトープシートの製造方法 |
| US8663210B2 (en) | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
| US8389041B2 (en) | 2010-06-17 | 2013-03-05 | Abbott Cardiovascular Systems, Inc. | Systems and methods for rotating and coating an implantable device |
| WO2012045040A1 (en) * | 2010-10-01 | 2012-04-05 | Varian Medical Systems, Inc. | Laser accelerator driven particle brachytherapy devices, systems, and methods |
| WO2012154762A1 (en) * | 2011-05-08 | 2012-11-15 | University Of Iowa Research Foundation | Compensator-based brachytherapy |
| WO2015175914A1 (en) * | 2014-05-16 | 2015-11-19 | Trustees Of Tufts College | Radioactive monolayer surface coating |
| WO2016087660A1 (en) * | 2014-12-04 | 2016-06-09 | General Electric Company | Method of manufacturing a radiation source |
| US9793010B2 (en) | 2015-02-19 | 2017-10-17 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| WO2016134163A1 (en) * | 2015-02-19 | 2016-08-25 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| US10522255B2 (en) | 2015-02-19 | 2019-12-31 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| JP6586616B2 (ja) * | 2015-02-24 | 2019-10-09 | 古河機械金属株式会社 | 放射能測定用標準試料、および放射能測定用標準試料の製造方法 |
| CA3091560A1 (en) * | 2018-03-08 | 2019-09-12 | Alpha Tau Medical Ltd. | Radiotherapy seeds and applicators |
| CN109754890B (zh) * | 2018-12-26 | 2020-11-03 | 北京工业大学 | 一种利用电流体动力学微液滴喷射的放射性籽源源芯的制作方法 |
| US11504546B2 (en) | 2019-02-28 | 2022-11-22 | Cowles Ventures, Llc | Needle guidance device for brachytherapy and method of use |
| US11524176B2 (en) | 2019-03-14 | 2022-12-13 | Cowles Ventures, Llc | Locator for placement of fiducial support device method |
| WO2024011452A1 (zh) * | 2022-07-13 | 2024-01-18 | 深圳先进技术研究院 | 一种薄膜的制备方法及其应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3351049A (en) * | 1965-04-12 | 1967-11-07 | Hazleton Nuclear Science Corp | Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture |
| DE1512650B2 (de) * | 1966-01-26 | 1971-10-07 | Xerox Corp , Rochester, N Y (V St A ) | Verfahren und einrichtung zur aufzeichnung von informationen mit einer elektroviskosen tinte |
| US3832222A (en) * | 1972-12-27 | 1974-08-27 | Atomic Energy Commission | Chemical vapor deposition of uranium and plutonium |
| US3811426A (en) * | 1973-05-21 | 1974-05-21 | Atomic Energy Commission | Method and apparatus for the in-vessel radiation treatment of blood |
| US4243694A (en) * | 1978-06-26 | 1981-01-06 | Whittaker Corporation | Jet ink process and ink composition fluorescent in ultraviolet light |
| US4228146A (en) * | 1978-10-27 | 1980-10-14 | Yuzo Imamura | Method of producing radioactive carbon powder |
| US4262206A (en) * | 1980-01-11 | 1981-04-14 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Fluorescent radiation converter |
| US4323055A (en) | 1980-04-08 | 1982-04-06 | Minnesota Mining And Manufacturing Company | Radioactive iodine seed |
| DE3574617D1 (de) * | 1984-09-11 | 1990-01-11 | Partec Ag | Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln. |
| US4702228A (en) | 1985-01-24 | 1987-10-27 | Theragenics Corporation | X-ray-emitting interstitial implants |
| US4729903A (en) * | 1986-06-10 | 1988-03-08 | Midi-Physics, Inc. | Process for depositing I-125 onto a substrate used to manufacture I-125 sources |
| US5132248A (en) * | 1988-05-31 | 1992-07-21 | The United States Of America As Represented By The United States Department Of Energy | Direct write with microelectronic circuit fabrication |
| GB8817997D0 (en) * | 1988-07-28 | 1988-09-01 | Cambridge Life Sciences | Enzyme electrodes & improvements in manufacture thereof |
| US4877699A (en) * | 1988-08-25 | 1989-10-31 | Eastman Kodak Company | Electrophotographic luminescent amplification process |
| DE69012096T2 (de) * | 1990-03-22 | 1995-01-12 | Canon Kk | Flüssigkeitsstrahlaufzeichnungskopf und Aufzeichnungsgerät, versehen mit diesem Kopf. |
| JPH0437821A (ja) * | 1990-06-04 | 1992-02-07 | Ajinomoto Co Inc | 液晶光学素子及びその製造方法 |
| US5342283A (en) * | 1990-08-13 | 1994-08-30 | Good Roger R | Endocurietherapy |
| US5281635A (en) * | 1991-05-17 | 1994-01-25 | Johnson Matthey Public Limited Company | Precious metal composition |
| US5449754A (en) * | 1991-08-07 | 1995-09-12 | H & N Instruments, Inc. | Generation of combinatorial libraries |
| JPH05235388A (ja) * | 1992-02-24 | 1993-09-10 | Mitsubishi Electric Corp | 低抵抗線状パターンの形成方法及び形成装置並びに太陽電池 |
| US5324359A (en) * | 1992-02-25 | 1994-06-28 | Nouvas Manufacturing Technology Co. | Material deposition device |
| DE4207962A1 (de) * | 1992-03-13 | 1993-09-16 | Solvay Umweltchemie Gmbh | Katalytisches wirbelschichtverfahren zur behandlung waessriger fluessigkeiten |
| JPH06145727A (ja) * | 1992-11-10 | 1994-05-27 | Mitsubishi Materials Corp | 球状パラジウム粉末の製造方法 |
| US5405309A (en) | 1993-04-28 | 1995-04-11 | Theragenics Corporation | X-ray emitting interstitial implants |
| US5643356A (en) * | 1993-08-05 | 1997-07-01 | Kimberly-Clark Corporation | Ink for ink jet printers |
| US5389593A (en) * | 1993-10-12 | 1995-02-14 | Uop | Pillared clay containing fluorided pillars |
| US5518680A (en) * | 1993-10-18 | 1996-05-21 | Massachusetts Institute Of Technology | Tissue regeneration matrices by solid free form fabrication techniques |
| US5490962A (en) * | 1993-10-18 | 1996-02-13 | Massachusetts Institute Of Technology | Preparation of medical devices by solid free-form fabrication methods |
| US5394816A (en) * | 1994-01-10 | 1995-03-07 | Kunstat; Robert M. | Marine fastener system with interchangeable identification tags |
| EP0682988B1 (en) * | 1994-05-18 | 2001-11-14 | Xerox Corporation | Acoustic deposition of material layers |
| US5882722A (en) * | 1995-07-12 | 1999-03-16 | Partnerships Limited, Inc. | Electrical conductors formed from mixtures of metal powders and metallo-organic decompositions compounds |
| US5713828A (en) * | 1995-11-27 | 1998-02-03 | International Brachytherapy S.A | Hollow-tube brachytherapy device |
-
1998
- 1998-05-27 US US09/085,357 patent/US6086942A/en not_active Expired - Lifetime
-
1999
- 1999-05-04 AU AU36247/99A patent/AU3624799A/en not_active Abandoned
- 1999-05-04 CA CA002331421A patent/CA2331421A1/en not_active Abandoned
- 1999-05-04 JP JP2000551397A patent/JP2002517006A/ja active Pending
- 1999-05-04 DE DE69919535T patent/DE69919535T2/de not_active Expired - Lifetime
- 1999-05-04 EP EP99918234A patent/EP1082729B1/en not_active Expired - Lifetime
- 1999-05-04 BR BR9911202-7A patent/BR9911202A/pt not_active Application Discontinuation
- 1999-05-04 WO PCT/IB1999/000914 patent/WO1999062074A1/en not_active Ceased
- 1999-05-04 CN CNB998066656A patent/CN1156857C/zh not_active Expired - Fee Related
-
2000
- 2000-07-05 US US09/609,834 patent/US6461433B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1082729B1 (en) | 2004-08-18 |
| CN1303513A (zh) | 2001-07-11 |
| JP2002517006A (ja) | 2002-06-11 |
| WO1999062074A1 (en) | 1999-12-02 |
| CA2331421A1 (en) | 1999-12-02 |
| AU3624799A (en) | 1999-12-13 |
| US6086942A (en) | 2000-07-11 |
| DE69919535D1 (de) | 2004-09-23 |
| US6461433B1 (en) | 2002-10-08 |
| BR9911202A (pt) | 2001-02-06 |
| EP1082729A1 (en) | 2001-03-14 |
| CN1156857C (zh) | 2004-07-07 |
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