JP2002517006A - 近接照射療法器具用放射性材料の液体ジェット被着法 - Google Patents
近接照射療法器具用放射性材料の液体ジェット被着法Info
- Publication number
- JP2002517006A JP2002517006A JP2000551397A JP2000551397A JP2002517006A JP 2002517006 A JP2002517006 A JP 2002517006A JP 2000551397 A JP2000551397 A JP 2000551397A JP 2000551397 A JP2000551397 A JP 2000551397A JP 2002517006 A JP2002517006 A JP 2002517006A
- Authority
- JP
- Japan
- Prior art keywords
- radioactive
- liquid
- radiation
- substrate
- radioactive liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 206
- 239000012857 radioactive material Substances 0.000 title claims abstract description 95
- 238000002725 brachytherapy Methods 0.000 title claims abstract description 74
- 238000001540 jet deposition Methods 0.000 title description 2
- 238000000034 method Methods 0.000 claims abstract description 127
- 230000005855 radiation Effects 0.000 claims abstract description 121
- 230000002285 radioactive effect Effects 0.000 claims abstract description 121
- 238000007639 printing Methods 0.000 claims abstract description 75
- 239000000758 substrate Substances 0.000 claims abstract description 72
- 239000000463 material Substances 0.000 claims abstract description 41
- 238000004519 manufacturing process Methods 0.000 claims abstract description 36
- 238000000151 deposition Methods 0.000 claims abstract description 25
- 150000001875 compounds Chemical class 0.000 claims abstract description 21
- 239000011230 binding agent Substances 0.000 claims abstract description 20
- 229920000178 Acrylic resin Polymers 0.000 claims abstract description 12
- 239000004925 Acrylic resin Substances 0.000 claims abstract description 12
- 150000003839 salts Chemical class 0.000 claims abstract description 12
- 239000004115 Sodium Silicate Substances 0.000 claims abstract description 9
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229910052911 sodium silicate Inorganic materials 0.000 claims abstract description 9
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 39
- 230000000694 effects Effects 0.000 claims description 34
- 238000007789 sealing Methods 0.000 claims description 27
- 239000002245 particle Substances 0.000 claims description 21
- 229910052763 palladium Inorganic materials 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 12
- 239000011248 coating agent Substances 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 9
- 238000005259 measurement Methods 0.000 claims description 8
- NXJCBFBQEVOTOW-UHFFFAOYSA-L palladium(2+);dihydroxide Chemical compound O[Pd]O NXJCBFBQEVOTOW-UHFFFAOYSA-L 0.000 claims description 8
- 125000001453 quaternary ammonium group Chemical group 0.000 claims description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 5
- 229910052740 iodine Inorganic materials 0.000 claims description 5
- 239000011630 iodine Substances 0.000 claims description 5
- VWQVUPCCIRVNHF-OUBTZVSYSA-N Yttrium-90 Chemical compound [90Y] VWQVUPCCIRVNHF-OUBTZVSYSA-N 0.000 claims description 4
- 238000004364 calculation method Methods 0.000 claims description 4
- 238000001959 radiotherapy Methods 0.000 claims description 4
- 230000002829 reductive effect Effects 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 239000003054 catalyst Substances 0.000 claims description 2
- 230000005670 electromagnetic radiation Effects 0.000 claims description 2
- SIWVEOZUMHYXCS-UHFFFAOYSA-N oxo(oxoyttriooxy)yttrium Chemical compound O=[Y]O[Y]=O SIWVEOZUMHYXCS-UHFFFAOYSA-N 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims 1
- 238000006555 catalytic reaction Methods 0.000 claims 1
- 238000004891 communication Methods 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 abstract description 16
- 239000010419 fine particle Substances 0.000 abstract description 13
- 239000010410 layer Substances 0.000 description 31
- 239000002243 precursor Substances 0.000 description 26
- 238000012937 correction Methods 0.000 description 25
- 230000008021 deposition Effects 0.000 description 17
- 238000001035 drying Methods 0.000 description 17
- 238000002347 injection Methods 0.000 description 16
- 239000007924 injection Substances 0.000 description 16
- 239000000976 ink Substances 0.000 description 16
- 230000008569 process Effects 0.000 description 16
- KDLHZDBZIXYQEI-OIOBTWANSA-N palladium-103 Chemical compound [103Pd] KDLHZDBZIXYQEI-OIOBTWANSA-N 0.000 description 15
- 238000007641 inkjet printing Methods 0.000 description 14
- 230000008859 change Effects 0.000 description 13
- 239000000203 mixture Substances 0.000 description 12
- 239000000243 solution Substances 0.000 description 12
- 206010028980 Neoplasm Diseases 0.000 description 11
- 230000009102 absorption Effects 0.000 description 11
- 238000010521 absorption reaction Methods 0.000 description 11
- PNDPGZBMCMUPRI-XXSWNUTMSA-N [125I][125I] Chemical compound [125I][125I] PNDPGZBMCMUPRI-XXSWNUTMSA-N 0.000 description 10
- 230000008901 benefit Effects 0.000 description 10
- 238000009826 distribution Methods 0.000 description 10
- 239000011347 resin Substances 0.000 description 10
- 229920005989 resin Polymers 0.000 description 10
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 9
- 238000005516 engineering process Methods 0.000 description 9
- 239000010936 titanium Substances 0.000 description 9
- 229910052719 titanium Inorganic materials 0.000 description 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 8
- 238000001994 activation Methods 0.000 description 8
- QWUZMTJBRUASOW-UHFFFAOYSA-N cadmium tellanylidenezinc Chemical compound [Zn].[Cd].[Te] QWUZMTJBRUASOW-UHFFFAOYSA-N 0.000 description 7
- 238000013461 design Methods 0.000 description 7
- 229920003023 plastic Polymers 0.000 description 7
- 239000004033 plastic Substances 0.000 description 7
- 239000011253 protective coating Substances 0.000 description 7
- 230000004913 activation Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 5
- 239000013078 crystal Substances 0.000 description 5
- 229910052751 metal Inorganic materials 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 4
- 239000000560 biocompatible material Substances 0.000 description 4
- 239000006229 carbon black Substances 0.000 description 4
- 239000012876 carrier material Substances 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 230000000704 physical effect Effects 0.000 description 4
- 239000011241 protective layer Substances 0.000 description 4
- 230000004044 response Effects 0.000 description 4
- 239000000741 silica gel Substances 0.000 description 4
- 229910002027 silica gel Inorganic materials 0.000 description 4
- 229910052709 silver Inorganic materials 0.000 description 4
- 239000004332 silver Substances 0.000 description 4
- 239000010457 zeolite Substances 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 3
- 229920000704 biodegradable plastic Polymers 0.000 description 3
- 238000004422 calculation algorithm Methods 0.000 description 3
- 238000005137 deposition process Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 238000005304 joining Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 229920005692 JONCRYL® Polymers 0.000 description 2
- 238000005411 Van der Waals force Methods 0.000 description 2
- 229910021536 Zeolite Inorganic materials 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 238000004590 computer program Methods 0.000 description 2
- 229920006238 degradable plastic Polymers 0.000 description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 239000011236 particulate material Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920002037 poly(vinyl butyral) polymer Polymers 0.000 description 2
- 229920006122 polyamide resin Polymers 0.000 description 2
- 239000004645 polyester resin Substances 0.000 description 2
- 229920001225 polyester resin Polymers 0.000 description 2
- 229920001470 polyketone Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000012254 powdered material Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000004064 recycling Methods 0.000 description 2
- 229920005792 styrene-acrylic resin Polymers 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000011277 treatment modality Methods 0.000 description 2
- 238000011269 treatment regimen Methods 0.000 description 2
- PCHJSUWPFVWCPO-NJFSPNSNSA-N (199au)gold Chemical compound [199Au] PCHJSUWPFVWCPO-NJFSPNSNSA-N 0.000 description 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- 108010033040 Histones Proteins 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-OUBTZVSYSA-N Phosphorus-32 Chemical compound [32P] OAICVXFJPJFONN-OUBTZVSYSA-N 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 208000007660 Residual Neoplasm Diseases 0.000 description 1
- 239000011358 absorbing material Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- LBDSXVIYZYSRII-IGMARMGPSA-N alpha-particle Chemical compound [4He+2] LBDSXVIYZYSRII-IGMARMGPSA-N 0.000 description 1
- LXQXZNRPTYVCNG-YPZZEJLDSA-N americium-241 Chemical compound [241Am] LXQXZNRPTYVCNG-YPZZEJLDSA-N 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 230000008512 biological response Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- BDOSMKKIYDKNTQ-OIOBTWANSA-N cadmium-109 Chemical compound [109Cd] BDOSMKKIYDKNTQ-OIOBTWANSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- PCHJSUWPFVWCPO-OUBTZVSYSA-N gold-198 Chemical compound [198Au] PCHJSUWPFVWCPO-OUBTZVSYSA-N 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229920000592 inorganic polymer Polymers 0.000 description 1
- 229940044173 iodine-125 Drugs 0.000 description 1
- GKOZUEZYRPOHIO-IGMARMGPSA-N iridium-192 Chemical compound [192Ir] GKOZUEZYRPOHIO-IGMARMGPSA-N 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000000155 isotopic effect Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 210000001165 lymph node Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000001394 metastastic effect Effects 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000009828 non-uniform distribution Methods 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 150000002940 palladium Chemical class 0.000 description 1
- PIBWKRNGBLPSSY-UHFFFAOYSA-L palladium(II) chloride Chemical compound Cl[Pd]Cl PIBWKRNGBLPSSY-UHFFFAOYSA-L 0.000 description 1
- YJVFFLUZDVXJQI-UHFFFAOYSA-L palladium(ii) acetate Chemical compound [Pd+2].CC([O-])=O.CC([O-])=O YJVFFLUZDVXJQI-UHFFFAOYSA-L 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 210000001539 phagocyte Anatomy 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 229940097886 phosphorus 32 Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000006223 plastic coating Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000005258 radioactive decay Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 231100000933 sensitization response Toxicity 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000004846 x-ray emission Methods 0.000 description 1
- VWQVUPCCIRVNHF-IGMARMGPSA-N yttrium-89 atom Chemical compound [89Y] VWQVUPCCIRVNHF-IGMARMGPSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/085,357 US6086942A (en) | 1998-05-27 | 1998-05-27 | Fluid-jet deposition of radioactive material for brachytherapy devices |
| US09/085,357 | 1998-05-27 | ||
| PCT/IB1999/000914 WO1999062074A1 (en) | 1998-05-27 | 1999-05-04 | Fluid-jet deposition of radioactive material for brachytherapy devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002517006A true JP2002517006A (ja) | 2002-06-11 |
| JP2002517006A5 JP2002517006A5 (enExample) | 2006-06-22 |
Family
ID=22191079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000551397A Pending JP2002517006A (ja) | 1998-05-27 | 1999-05-04 | 近接照射療法器具用放射性材料の液体ジェット被着法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6086942A (enExample) |
| EP (1) | EP1082729B1 (enExample) |
| JP (1) | JP2002517006A (enExample) |
| CN (1) | CN1156857C (enExample) |
| AU (1) | AU3624799A (enExample) |
| BR (1) | BR9911202A (enExample) |
| CA (1) | CA2331421A1 (enExample) |
| DE (1) | DE69919535T2 (enExample) |
| WO (1) | WO1999062074A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006515810A (ja) * | 2003-01-17 | 2006-06-08 | シクパ・ホールディング・ソシエテ・アノニム | 物体に暫定的に印を付ける方法、装置及びシステム |
| JP2009542318A (ja) * | 2006-06-28 | 2009-12-03 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ステントコーティングの方法および装置 |
| JP2010048804A (ja) * | 2008-07-31 | 2010-03-04 | Eckert & Ziegler Isotope Products Inc | 放射線フラッドソースを形成する方法、放射線フラッドソースを形成するためのプロッティングシステム、および放射線フラッドソース |
| JP2010127825A (ja) * | 2008-11-28 | 2010-06-10 | Japan Atomic Energy Agency | ラジオアイソトープシートの製造方法、該製造方法により製造されるラジオアイソトープシート及びラジオアイソトープ装置 |
| JP2016156698A (ja) * | 2015-02-24 | 2016-09-01 | 古河機械金属株式会社 | 放射能測定用標準試料、および放射能測定用標準試料の製造方法 |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60128463T2 (de) | 2000-04-28 | 2008-04-10 | Qsa Global Gmbh | Flutstrahlungsquelle und zugehöriges erzeugungsverfahren |
| WO2002027630A1 (en) * | 2000-09-28 | 2002-04-04 | Isostar Texas, Inc. | Fast photon counting assay system and method |
| WO2004026111A2 (en) | 2000-11-16 | 2004-04-01 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
| US6517890B2 (en) * | 2001-02-22 | 2003-02-11 | European Community | Thin layer preparation for radionuclide sources |
| US6623785B2 (en) * | 2001-06-07 | 2003-09-23 | Hewlett-Packard Development Company, L.P. | Pharmaceutical dispensing apparatus and method |
| US6723052B2 (en) * | 2001-06-07 | 2004-04-20 | Stanley L. Mills | Echogenic medical device |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| US6702894B2 (en) | 2001-10-24 | 2004-03-09 | Hewlett-Packard Development Company, L.P. | Fluid ejection cartridge and system for dispensing a bioactive substance |
| US6787786B2 (en) * | 2001-06-12 | 2004-09-07 | North American Scientific, Inc. | Thin radiation source and method of making the same |
| US7074291B2 (en) * | 2001-11-02 | 2006-07-11 | Worldwide Medical Technologies, L.L.C. | Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings |
| US7060020B2 (en) | 2001-11-02 | 2006-06-13 | Ideamatrix, Inc. | Delivery system and method for interstitial radiation therapy |
| US6786591B2 (en) | 2002-10-24 | 2004-09-07 | Hewlett-Packard Development Company, L.P. | Fluid ejector apparatus and methods |
| US20040081689A1 (en) * | 2002-10-24 | 2004-04-29 | Dunfield John Stephen | Pharmaceutical dosage form and method of making |
| EP1572029B1 (en) * | 2002-11-07 | 2010-03-24 | Abbott Laboratories | Method of loading beneficial agent to a prosthesis by fluid-jet application |
| US8221495B2 (en) | 2002-11-07 | 2012-07-17 | Abbott Laboratories | Integration of therapeutic agent into a bioerodible medical device |
| US8524148B2 (en) * | 2002-11-07 | 2013-09-03 | Abbott Laboratories | Method of integrating therapeutic agent into a bioerodible medical device |
| DE10306072B4 (de) * | 2003-02-13 | 2009-04-02 | Veritas Ag | Mehrschichtiger Schlauch |
| GB0305848D0 (en) * | 2003-03-14 | 2003-04-16 | Imaging Res Solutions Ltd | Radiopharmaceutical generation system |
| DE102004022200B4 (de) * | 2004-05-05 | 2006-07-20 | Actinium Pharmaceuticals, Inc. | Radium-Target sowie Verfahren zu seiner Herstellung |
| US8609198B2 (en) | 2004-07-21 | 2013-12-17 | Hewlett-Packard Development Company, L.P. | Pharmaceutical dose form with a patterned coating and method of making the same |
| US20060023843A1 (en) * | 2004-07-27 | 2006-02-02 | Kusch Jochen K | Cone-beam imaging for brachytherapy |
| US8187159B2 (en) | 2005-07-22 | 2012-05-29 | Biocompatibles, UK | Therapeutic member including a rail used in brachytherapy and other radiation therapy |
| US7736293B2 (en) * | 2005-07-22 | 2010-06-15 | Biocompatibles Uk Limited | Implants for use in brachytherapy and other radiation therapy that resist migration and rotation |
| DE102006008023B4 (de) * | 2006-02-21 | 2008-05-29 | Actinium Pharmaceuticals, Inc. | Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets |
| US7988611B2 (en) | 2006-05-09 | 2011-08-02 | Biocompatibles Uk Limited | After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy |
| US20090216063A1 (en) * | 2008-01-29 | 2009-08-27 | Biocompatibles Uk Limited | Bio-absorbable brachytherapy strands |
| WO2008027402A2 (en) * | 2006-08-29 | 2008-03-06 | Civatech Oncology | Brachytherapy devices and related methods and computer program products |
| US7878964B1 (en) | 2006-09-07 | 2011-02-01 | Biocompatibles Uk Limited | Echogenic spacers and strands |
| US7874976B1 (en) | 2006-09-07 | 2011-01-25 | Biocompatibles Uk Limited | Echogenic strands and spacers therein |
| CA2662932C (en) | 2006-09-08 | 2017-06-06 | Actinium Pharmaceuticals, Inc. | Method for the purification of radium from different sources |
| US8733274B2 (en) * | 2006-10-20 | 2014-05-27 | Hewlett-Packard Development Company, L.P. | Tube mounted inkjet printhead die |
| US7867548B2 (en) * | 2006-10-27 | 2011-01-11 | Hewlett-Packard Development Company, L.P. | Thermal ejection of solution having solute onto device medium |
| CA2760013C (en) * | 2008-05-02 | 2017-02-14 | Civatech Oncology | Brachytherapy devices and related methods and computer program products |
| US8663210B2 (en) | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
| US8389041B2 (en) | 2010-06-17 | 2013-03-05 | Abbott Cardiovascular Systems, Inc. | Systems and methods for rotating and coating an implantable device |
| WO2012045040A1 (en) * | 2010-10-01 | 2012-04-05 | Varian Medical Systems, Inc. | Laser accelerator driven particle brachytherapy devices, systems, and methods |
| WO2012154762A1 (en) * | 2011-05-08 | 2012-11-15 | University Of Iowa Research Foundation | Compensator-based brachytherapy |
| WO2015175914A1 (en) * | 2014-05-16 | 2015-11-19 | Trustees Of Tufts College | Radioactive monolayer surface coating |
| WO2016087660A1 (en) * | 2014-12-04 | 2016-06-09 | General Electric Company | Method of manufacturing a radiation source |
| US9793010B2 (en) | 2015-02-19 | 2017-10-17 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| WO2016134163A1 (en) * | 2015-02-19 | 2016-08-25 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| US10522255B2 (en) | 2015-02-19 | 2019-12-31 | X-Energy, Llc | Nuclear fuel pebble and method of manufacturing the same |
| CA3091560A1 (en) * | 2018-03-08 | 2019-09-12 | Alpha Tau Medical Ltd. | Radiotherapy seeds and applicators |
| CN109754890B (zh) * | 2018-12-26 | 2020-11-03 | 北京工业大学 | 一种利用电流体动力学微液滴喷射的放射性籽源源芯的制作方法 |
| US11504546B2 (en) | 2019-02-28 | 2022-11-22 | Cowles Ventures, Llc | Needle guidance device for brachytherapy and method of use |
| US11524176B2 (en) | 2019-03-14 | 2022-12-13 | Cowles Ventures, Llc | Locator for placement of fiducial support device method |
| WO2024011452A1 (zh) * | 2022-07-13 | 2024-01-18 | 深圳先进技术研究院 | 一种薄膜的制备方法及其应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3351049A (en) * | 1965-04-12 | 1967-11-07 | Hazleton Nuclear Science Corp | Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture |
| DE1512650B2 (de) * | 1966-01-26 | 1971-10-07 | Xerox Corp , Rochester, N Y (V St A ) | Verfahren und einrichtung zur aufzeichnung von informationen mit einer elektroviskosen tinte |
| US3832222A (en) * | 1972-12-27 | 1974-08-27 | Atomic Energy Commission | Chemical vapor deposition of uranium and plutonium |
| US3811426A (en) * | 1973-05-21 | 1974-05-21 | Atomic Energy Commission | Method and apparatus for the in-vessel radiation treatment of blood |
| US4243694A (en) * | 1978-06-26 | 1981-01-06 | Whittaker Corporation | Jet ink process and ink composition fluorescent in ultraviolet light |
| US4228146A (en) * | 1978-10-27 | 1980-10-14 | Yuzo Imamura | Method of producing radioactive carbon powder |
| US4262206A (en) * | 1980-01-11 | 1981-04-14 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Fluorescent radiation converter |
| US4323055A (en) | 1980-04-08 | 1982-04-06 | Minnesota Mining And Manufacturing Company | Radioactive iodine seed |
| DE3574617D1 (de) * | 1984-09-11 | 1990-01-11 | Partec Ag | Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln. |
| US4702228A (en) | 1985-01-24 | 1987-10-27 | Theragenics Corporation | X-ray-emitting interstitial implants |
| US4729903A (en) * | 1986-06-10 | 1988-03-08 | Midi-Physics, Inc. | Process for depositing I-125 onto a substrate used to manufacture I-125 sources |
| US5132248A (en) * | 1988-05-31 | 1992-07-21 | The United States Of America As Represented By The United States Department Of Energy | Direct write with microelectronic circuit fabrication |
| GB8817997D0 (en) * | 1988-07-28 | 1988-09-01 | Cambridge Life Sciences | Enzyme electrodes & improvements in manufacture thereof |
| US4877699A (en) * | 1988-08-25 | 1989-10-31 | Eastman Kodak Company | Electrophotographic luminescent amplification process |
| DE69012096T2 (de) * | 1990-03-22 | 1995-01-12 | Canon Kk | Flüssigkeitsstrahlaufzeichnungskopf und Aufzeichnungsgerät, versehen mit diesem Kopf. |
| JPH0437821A (ja) * | 1990-06-04 | 1992-02-07 | Ajinomoto Co Inc | 液晶光学素子及びその製造方法 |
| US5342283A (en) * | 1990-08-13 | 1994-08-30 | Good Roger R | Endocurietherapy |
| US5281635A (en) * | 1991-05-17 | 1994-01-25 | Johnson Matthey Public Limited Company | Precious metal composition |
| US5449754A (en) * | 1991-08-07 | 1995-09-12 | H & N Instruments, Inc. | Generation of combinatorial libraries |
| JPH05235388A (ja) * | 1992-02-24 | 1993-09-10 | Mitsubishi Electric Corp | 低抵抗線状パターンの形成方法及び形成装置並びに太陽電池 |
| US5324359A (en) * | 1992-02-25 | 1994-06-28 | Nouvas Manufacturing Technology Co. | Material deposition device |
| DE4207962A1 (de) * | 1992-03-13 | 1993-09-16 | Solvay Umweltchemie Gmbh | Katalytisches wirbelschichtverfahren zur behandlung waessriger fluessigkeiten |
| JPH06145727A (ja) * | 1992-11-10 | 1994-05-27 | Mitsubishi Materials Corp | 球状パラジウム粉末の製造方法 |
| US5405309A (en) | 1993-04-28 | 1995-04-11 | Theragenics Corporation | X-ray emitting interstitial implants |
| US5643356A (en) * | 1993-08-05 | 1997-07-01 | Kimberly-Clark Corporation | Ink for ink jet printers |
| US5389593A (en) * | 1993-10-12 | 1995-02-14 | Uop | Pillared clay containing fluorided pillars |
| US5518680A (en) * | 1993-10-18 | 1996-05-21 | Massachusetts Institute Of Technology | Tissue regeneration matrices by solid free form fabrication techniques |
| US5490962A (en) * | 1993-10-18 | 1996-02-13 | Massachusetts Institute Of Technology | Preparation of medical devices by solid free-form fabrication methods |
| US5394816A (en) * | 1994-01-10 | 1995-03-07 | Kunstat; Robert M. | Marine fastener system with interchangeable identification tags |
| EP0682988B1 (en) * | 1994-05-18 | 2001-11-14 | Xerox Corporation | Acoustic deposition of material layers |
| US5882722A (en) * | 1995-07-12 | 1999-03-16 | Partnerships Limited, Inc. | Electrical conductors formed from mixtures of metal powders and metallo-organic decompositions compounds |
| US5713828A (en) * | 1995-11-27 | 1998-02-03 | International Brachytherapy S.A | Hollow-tube brachytherapy device |
-
1998
- 1998-05-27 US US09/085,357 patent/US6086942A/en not_active Expired - Lifetime
-
1999
- 1999-05-04 AU AU36247/99A patent/AU3624799A/en not_active Abandoned
- 1999-05-04 CA CA002331421A patent/CA2331421A1/en not_active Abandoned
- 1999-05-04 JP JP2000551397A patent/JP2002517006A/ja active Pending
- 1999-05-04 DE DE69919535T patent/DE69919535T2/de not_active Expired - Lifetime
- 1999-05-04 EP EP99918234A patent/EP1082729B1/en not_active Expired - Lifetime
- 1999-05-04 BR BR9911202-7A patent/BR9911202A/pt not_active Application Discontinuation
- 1999-05-04 WO PCT/IB1999/000914 patent/WO1999062074A1/en not_active Ceased
- 1999-05-04 CN CNB998066656A patent/CN1156857C/zh not_active Expired - Fee Related
-
2000
- 2000-07-05 US US09/609,834 patent/US6461433B1/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006515810A (ja) * | 2003-01-17 | 2006-06-08 | シクパ・ホールディング・ソシエテ・アノニム | 物体に暫定的に印を付ける方法、装置及びシステム |
| JP2009542318A (ja) * | 2006-06-28 | 2009-12-03 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ステントコーティングの方法および装置 |
| JP2010048804A (ja) * | 2008-07-31 | 2010-03-04 | Eckert & Ziegler Isotope Products Inc | 放射線フラッドソースを形成する方法、放射線フラッドソースを形成するためのプロッティングシステム、および放射線フラッドソース |
| JP2010127825A (ja) * | 2008-11-28 | 2010-06-10 | Japan Atomic Energy Agency | ラジオアイソトープシートの製造方法、該製造方法により製造されるラジオアイソトープシート及びラジオアイソトープ装置 |
| JP2016156698A (ja) * | 2015-02-24 | 2016-09-01 | 古河機械金属株式会社 | 放射能測定用標準試料、および放射能測定用標準試料の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1082729B1 (en) | 2004-08-18 |
| CN1303513A (zh) | 2001-07-11 |
| WO1999062074A1 (en) | 1999-12-02 |
| CA2331421A1 (en) | 1999-12-02 |
| AU3624799A (en) | 1999-12-13 |
| US6086942A (en) | 2000-07-11 |
| DE69919535D1 (de) | 2004-09-23 |
| US6461433B1 (en) | 2002-10-08 |
| BR9911202A (pt) | 2001-02-06 |
| DE69919535T2 (de) | 2005-05-12 |
| EP1082729A1 (en) | 2001-03-14 |
| CN1156857C (zh) | 2004-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002517006A (ja) | 近接照射療法器具用放射性材料の液体ジェット被着法 | |
| DE69130944T2 (de) | Endocurietherapie | |
| AU2021400142B2 (en) | Diffusing alpha-emitters radiation therapy with enhanced beta treatment | |
| US6749553B2 (en) | Radiation delivery devices and methods for their manufacture | |
| US6986880B2 (en) | Polymeric-matrix brachytherapy sources | |
| US5342283A (en) | Endocurietherapy | |
| EP2293842B1 (en) | Brachytherapy devices and related methods | |
| US6391279B1 (en) | Radioactive seeds for brachytherapy and a process for making the same | |
| AU2019247818A1 (en) | Controlled release of radionuclides | |
| JP2002320684A (ja) | カプセルシード | |
| WO1997019706A9 (en) | Radioisotope dispersed in a matrix for brachytherapy | |
| AU2001266592A1 (en) | Radiation delivery devices and methods for their manufacture | |
| EP1169087B1 (en) | Method and apparatus for loading delivery systems for brachytherapy seeds | |
| US6761679B2 (en) | Embedded radiation emitter for the localization and dosimetry of brachytherapy seed implants | |
| JP2007510496A (ja) | 近接照射療法のインプラントシードを製造する方法 | |
| EP1008995A1 (en) | Medical radioactive palladium-103 miniature radiation sources and methods of producing same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060427 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060427 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090210 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090508 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090515 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090811 |