DE69916302D1 - Verwendung von dendritischen zellen-depletierten zusammensetzungen zur verbesserung der transplantation von allogenen hämatopoietischen zellen - Google Patents

Verwendung von dendritischen zellen-depletierten zusammensetzungen zur verbesserung der transplantation von allogenen hämatopoietischen zellen

Info

Publication number
DE69916302D1
DE69916302D1 DE69916302T DE69916302T DE69916302D1 DE 69916302 D1 DE69916302 D1 DE 69916302D1 DE 69916302 T DE69916302 T DE 69916302T DE 69916302 T DE69916302 T DE 69916302T DE 69916302 D1 DE69916302 D1 DE 69916302D1
Authority
DE
Germany
Prior art keywords
cells
hematopoietic system
transplantation
recipient
dendritic cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69916302T
Other languages
English (en)
Other versions
DE69916302T2 (de
Inventor
K Waller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
Original Assignee
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Application granted granted Critical
Publication of DE69916302D1 publication Critical patent/DE69916302D1/de
Publication of DE69916302T2 publication Critical patent/DE69916302T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
DE69916302T 1998-11-11 1999-11-10 Verwendung von dendritischen zellen-depletierten zusammensetzungen zur verbesserung der transplantation von allogenen hämatopoietischen zellen Expired - Fee Related DE69916302T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18957798A 1998-11-11 1998-11-11
US189577 1998-11-11
PCT/US1999/026773 WO2000027998A2 (en) 1998-11-11 1999-11-10 Method and compositions for improving allogeneic hematopoietic cell transplantation

Publications (2)

Publication Number Publication Date
DE69916302D1 true DE69916302D1 (de) 2004-05-13
DE69916302T2 DE69916302T2 (de) 2005-05-04

Family

ID=22697926

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916302T Expired - Fee Related DE69916302T2 (de) 1998-11-11 1999-11-10 Verwendung von dendritischen zellen-depletierten zusammensetzungen zur verbesserung der transplantation von allogenen hämatopoietischen zellen

Country Status (9)

Country Link
EP (1) EP1123384B1 (de)
JP (1) JP2002529476A (de)
KR (1) KR20010090008A (de)
CN (1) CN1213143C (de)
AT (1) ATE263833T1 (de)
AU (1) AU779039B2 (de)
CA (1) CA2351194A1 (de)
DE (1) DE69916302T2 (de)
WO (1) WO2000027998A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010002242A (es) 2007-08-31 2010-06-01 Whitehead Biomedical Inst Estimulación de ruta wnt en reprogramacion de celulas somaticas.
JP6096677B2 (ja) * 2011-01-10 2017-03-15 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 同種造血幹細胞移植の増強

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409813A (en) * 1993-09-30 1995-04-25 Systemix, Inc. Method for mammalian cell separation from a mixture of cell populations

Also Published As

Publication number Publication date
AU1817800A (en) 2000-05-29
CN1213143C (zh) 2005-08-03
WO2000027998A3 (en) 2000-07-27
WO2000027998A2 (en) 2000-05-18
DE69916302T2 (de) 2005-05-04
CN1333688A (zh) 2002-01-30
KR20010090008A (ko) 2001-10-17
EP1123384A2 (de) 2001-08-16
CA2351194A1 (en) 2000-05-18
AU779039B2 (en) 2005-01-06
EP1123384B1 (de) 2004-04-07
JP2002529476A (ja) 2002-09-10
ATE263833T1 (de) 2004-04-15

Similar Documents

Publication Publication Date Title
JP2002517227A5 (ja) 造血幹細胞を試験管内で維持する方法と組成物
Yañez et al. Adipose tissue‐derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft‐versus‐host disease
Garcia‐Castro et al. Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool
EP2048228B8 (de) Humane Lebervorläufer
GB2432846B (en) Medium and culture of embryonic stem cells
SG152273A1 (en) Pdx1 expressing endoderm
WO2005097979A3 (en) Methods and compositions for obtaining hematopoietic stem cells derived from embryonic stem cells and uses thereof
WO2006047743A3 (en) Swine multipotent adult progenitor cells
WO2003012060A3 (en) Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd
EP1077599A4 (de) Brassica-transformation durch teilchenbeschuss
ATE300310T1 (de) Verfahren zur steigerung von hematopoietischen zellen
DK0952772T3 (da) Fremgangsmåder til anvendelse af mononukleare phagocytter til at fremme axonal regeneration
BR9612821A (pt) Métodos para a prevenção de rejeição de enxerto em transplante e para a produção de uma célula de hospedeiro para terapia genética universal
WO2009035612A3 (en) Multilineage-inducible cells and uses thereof
EP2377922A3 (de) PDX1-exprimierendes Endoderm
DE69916302D1 (de) Verwendung von dendritischen zellen-depletierten zusammensetzungen zur verbesserung der transplantation von allogenen hämatopoietischen zellen
DE69737455D1 (de) Definierte systeme zur kultivieurng epithelialer zellen und anwendung derselben
WO2005017115A3 (en) Cord blood-derived hematopoietic progenitor cells
WO2005032463A3 (en) Educated nkt cells and their uses in the treatment of immune-related disorders
WO2003029432A3 (en) Human mesenchymal progenitor cell
ATE225183T1 (de) Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
DK1140149T3 (da) Anvendelse af humant væksthormon til forögelse af antallet af cirkulerende CD34+-celler, tilsigtet til genetablering af de hematopoietiske system og immunsystemet fölgende myeloablative eller antibalstiske terapier ved transplantation......
GB2379446A (en) Cells,culture methods and their uses
PT765398E (pt) Populacao de celulas enriquecedoras em progenitores mieloides e linfoides e metodos de as fazer e utilizar
Ji et al. Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee