DE69915160D1 - Verfahren zur Herstellung des Somatostatin Analogons Octreotide - Google Patents
Verfahren zur Herstellung des Somatostatin Analogons OctreotideInfo
- Publication number
- DE69915160D1 DE69915160D1 DE69915160T DE69915160T DE69915160D1 DE 69915160 D1 DE69915160 D1 DE 69915160D1 DE 69915160 T DE69915160 T DE 69915160T DE 69915160 T DE69915160 T DE 69915160T DE 69915160 D1 DE69915160 D1 DE 69915160D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- somatostatin analog
- analog octreotide
- octreotide
- somatostatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9800162 | 1998-01-29 | ||
ES009800162A ES2144357B1 (es) | 1998-01-29 | 1998-01-29 | Procedimiento para la obtencion del analogo de somatostatina octreotide. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69915160D1 true DE69915160D1 (de) | 2004-04-08 |
DE69915160T2 DE69915160T2 (de) | 2005-01-20 |
Family
ID=8302556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69915160T Expired - Lifetime DE69915160T2 (de) | 1998-01-29 | 1999-01-27 | Verfahren zur Herstellung des Somatostatin Analogons Octreotide |
Country Status (4)
Country | Link |
---|---|
US (1) | US6346601B1 (de) |
EP (1) | EP0953577B1 (de) |
DE (1) | DE69915160T2 (de) |
ES (2) | ES2144357B1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6476186B1 (en) * | 2000-05-23 | 2002-11-05 | Institute Of Nuclear Energy Research | Process for preparing octreotide and derivatives thereof |
US7189856B2 (en) * | 2001-12-28 | 2007-03-13 | Gideon Shapiro | Non-peptide somatostatin receptor ligands |
DK1480998T3 (da) * | 2002-02-27 | 2007-03-26 | Ferring Bv | Mellemprodukter og fremgangsmåder til fremstilling af heptapeptidoxytocinanaloger |
US6987167B2 (en) | 2002-05-22 | 2006-01-17 | Wockhardt Limited | Process for production of the somatostatin analog, octreotide |
CN100338090C (zh) * | 2002-12-17 | 2007-09-19 | 常州市第四制药厂有限公司 | 生长抑素全合成新方法 |
ES2237356T3 (es) * | 2003-04-07 | 2007-04-01 | Novetide Ltd. | Procedimiento para la produccion de peptidos ciclicos. |
CA2458084A1 (en) * | 2004-03-12 | 2005-09-12 | Dalton Chemical Laboratories Inc. | Novel process for octreotide synthesis |
KR100998175B1 (ko) | 2008-05-30 | 2010-12-03 | 애니젠 주식회사 | 소마토스타틴의 제조방법 |
TWI394585B (zh) * | 2008-07-25 | 2013-05-01 | Iner Aec Executive Yuan | The magnetic fluid used for the development or treatment of peptides |
WO2010089757A2 (en) | 2008-11-07 | 2010-08-12 | Usv Limited | An improved process for synthesis of cyclic octapeptide |
US20140296144A1 (en) | 2011-09-30 | 2014-10-02 | Mylan Laboratories, Ltd. | Process for the preparation of octreotide acetate |
WO2013132505A1 (en) | 2012-03-09 | 2013-09-12 | Natco Pharma Limited | Improved process for preparation of octreotide by solution phase peptide synthesis |
CN112500450A (zh) * | 2019-09-16 | 2021-03-16 | 翰宇药业(武汉)有限公司 | 一种奥曲肽的合成方法 |
CN112778400A (zh) * | 2021-02-05 | 2021-05-11 | 合肥科生景肽生物科技有限公司 | 一种奥曲肽的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE2512T1 (de) * | 1979-11-27 | 1983-03-15 | Sandoz Ag | Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung. |
EP0824103A1 (de) * | 1996-08-13 | 1998-02-18 | Chang-Shinn Su | Verfahren zur Synthese von Tyr-3-octreotid |
-
1998
- 1998-01-29 ES ES009800162A patent/ES2144357B1/es not_active Expired - Lifetime
-
1999
- 1999-01-27 EP EP99500012A patent/EP0953577B1/de not_active Expired - Lifetime
- 1999-01-27 ES ES99500012T patent/ES2217717T3/es not_active Expired - Lifetime
- 1999-01-27 DE DE69915160T patent/DE69915160T2/de not_active Expired - Lifetime
- 1999-01-29 US US09/240,145 patent/US6346601B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0953577B1 (de) | 2004-03-03 |
US6346601B1 (en) | 2002-02-12 |
DE69915160T2 (de) | 2005-01-20 |
ES2144357A1 (es) | 2000-06-01 |
ES2144357B1 (es) | 2000-12-16 |
ES2217717T3 (es) | 2004-11-01 |
EP0953577A1 (de) | 1999-11-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69930540D1 (de) | Verfahren zur herstellung von silalkylen-siloxancopolymeren | |
DE69838770D1 (de) | Verfahren zur Herstellung elektrolumineszierender Vorrichtungen | |
DE60019747D1 (de) | Verfahren zur herstellung von fluorolefinen | |
DE69915160D1 (de) | Verfahren zur Herstellung des Somatostatin Analogons Octreotide | |
DE69803646D1 (de) | Verfahren zur Herstellung der epsilon polymorphischen Form des Hexanitrohexaazaisowurtzitan | |
DE59808528D1 (de) | Verfahren zur Herstellung von 3-Glycidyloxypropyltrialkoxysilanen | |
DE60205955D1 (de) | Verfahren zur Herstellung von L-Aminosäuren | |
DE59809042D1 (de) | Verfahren zur Herstellung SiOH-funktioneller Carbosilan-Dendrimere | |
DE59702654D1 (de) | Verfahren zur Herstellung von Methylchlorsilanen | |
DE60001015D1 (de) | Verfahren zur Herstellung von Canthaxanthin | |
DE60024372D1 (de) | Verfahren zur Herstellung von Tetraorganooxysilanen | |
DE59900916D1 (de) | Verfahren zur Herstellung von 4-Aminodiphenylamin | |
DE59905990D1 (de) | Verfahren zur Herstellung von Trifluorbenzoesäuren | |
DE69903398D1 (de) | Verfahren zur Herstellung von 2-Alkyl-3-hydroxybenzoesäuren | |
DE60031231D1 (de) | Verfahren zur Herstellung von 2-Alkyl-4-Isothiazolin-3-onen | |
DE69836928D1 (de) | Verbindungen und Verfahren zur Herstellung substituierter 4-Phenyl-4-cyanocyclohexansäuren | |
DE60043610D1 (de) | Verfahren zur herstellung von l-lysin | |
DE59902434D1 (de) | Verfahren zur Herstellung von Isochroman-3-onen | |
DE60004119D1 (de) | Verfahren zur Herstellung von Pentaacetyl-beta-D-Glucopyranose | |
DE50003603D1 (de) | Verfahren zur Herstellung von Bistrifluormethylbenzylaminen | |
DE60002254T2 (de) | Verfahren zur Herstellung von 4,6-diaminoresorcin | |
DE69927462D1 (de) | Verfahren zur Herstellung von Polyorganosiloxangummi | |
DE50001772D1 (de) | Verfahren zur Herstellung von Nitrodiphenylaminen | |
DE50006464D1 (de) | Verfahren zur Herstellung von Arylaminohydroxyanthrachinonen | |
DE60002513D1 (de) | Verfahren zur Herstellung von Dimethyltetralin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Ref document number: 953577 Country of ref document: EP Representative=s name: RACKETTE PARTNERSCHAFT PATENTANWAELTE, DE |
|
R081 | Change of applicant/patentee |
Ref document number: 953577 Country of ref document: EP Owner name: BCN PEPTIDES, S.A., ES Free format text: FORMER OWNER: LIPOTEC, S.A., GAVA, ES Effective date: 20120820 Ref document number: 953577 Country of ref document: EP Owner name: BCN PEPTIDES SA, ES Free format text: FORMER OWNER: LIPOTEC, S.A., GAVA, ES Effective date: 20120820 |
|
R082 | Change of representative |
Ref document number: 953577 Country of ref document: EP Representative=s name: RACKETTE PARTNERSCHAFT PATENTANWAELTE, DE Effective date: 20120820 |
|
R082 | Change of representative |
Ref document number: 953577 Country of ref document: EP Representative=s name: RACKETTE PARTNERSCHAFT PATENTANWAELTE, DE |
|
R081 | Change of applicant/patentee |
Ref document number: 953577 Country of ref document: EP Owner name: BCN PEPTIDES SA, ES Free format text: FORMER OWNER: BCN PEPTIDES, S.A., GAVA, ES Effective date: 20121015 |
|
R082 | Change of representative |
Ref document number: 953577 Country of ref document: EP Representative=s name: RACKETTE PARTNERSCHAFT PATENTANWAELTE, DE Effective date: 20121015 |