DE69915160D1 - Verfahren zur Herstellung des Somatostatin Analogons Octreotide - Google Patents

Verfahren zur Herstellung des Somatostatin Analogons Octreotide

Info

Publication number
DE69915160D1
DE69915160D1 DE69915160T DE69915160T DE69915160D1 DE 69915160 D1 DE69915160 D1 DE 69915160D1 DE 69915160 T DE69915160 T DE 69915160T DE 69915160 T DE69915160 T DE 69915160T DE 69915160 D1 DE69915160 D1 DE 69915160D1
Authority
DE
Germany
Prior art keywords
preparation
somatostatin analog
analog octreotide
octreotide
somatostatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69915160T
Other languages
English (en)
Other versions
DE69915160T2 (de
Inventor
Rodriguez Francisco J Clemente
Obiols Berta Ponsati
Farres Gemma Jodas
Poblet Marc Canas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BCN PEPTIDES SA, ES
Original Assignee
Lipotec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipotec SA filed Critical Lipotec SA
Publication of DE69915160D1 publication Critical patent/DE69915160D1/de
Application granted granted Critical
Publication of DE69915160T2 publication Critical patent/DE69915160T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69915160T 1998-01-29 1999-01-27 Verfahren zur Herstellung des Somatostatin Analogons Octreotide Expired - Lifetime DE69915160T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9800162 1998-01-29
ES009800162A ES2144357B1 (es) 1998-01-29 1998-01-29 Procedimiento para la obtencion del analogo de somatostatina octreotide.

Publications (2)

Publication Number Publication Date
DE69915160D1 true DE69915160D1 (de) 2004-04-08
DE69915160T2 DE69915160T2 (de) 2005-01-20

Family

ID=8302556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915160T Expired - Lifetime DE69915160T2 (de) 1998-01-29 1999-01-27 Verfahren zur Herstellung des Somatostatin Analogons Octreotide

Country Status (4)

Country Link
US (1) US6346601B1 (de)
EP (1) EP0953577B1 (de)
DE (1) DE69915160T2 (de)
ES (2) ES2144357B1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476186B1 (en) * 2000-05-23 2002-11-05 Institute Of Nuclear Energy Research Process for preparing octreotide and derivatives thereof
US7189856B2 (en) * 2001-12-28 2007-03-13 Gideon Shapiro Non-peptide somatostatin receptor ligands
DK1480998T3 (da) * 2002-02-27 2007-03-26 Ferring Bv Mellemprodukter og fremgangsmåder til fremstilling af heptapeptidoxytocinanaloger
US6987167B2 (en) 2002-05-22 2006-01-17 Wockhardt Limited Process for production of the somatostatin analog, octreotide
CN100338090C (zh) * 2002-12-17 2007-09-19 常州市第四制药厂有限公司 生长抑素全合成新方法
ES2237356T3 (es) * 2003-04-07 2007-04-01 Novetide Ltd. Procedimiento para la produccion de peptidos ciclicos.
CA2458084A1 (en) * 2004-03-12 2005-09-12 Dalton Chemical Laboratories Inc. Novel process for octreotide synthesis
KR100998175B1 (ko) 2008-05-30 2010-12-03 애니젠 주식회사 소마토스타틴의 제조방법
TWI394585B (zh) * 2008-07-25 2013-05-01 Iner Aec Executive Yuan The magnetic fluid used for the development or treatment of peptides
WO2010089757A2 (en) 2008-11-07 2010-08-12 Usv Limited An improved process for synthesis of cyclic octapeptide
US20140296144A1 (en) 2011-09-30 2014-10-02 Mylan Laboratories, Ltd. Process for the preparation of octreotide acetate
WO2013132505A1 (en) 2012-03-09 2013-09-12 Natco Pharma Limited Improved process for preparation of octreotide by solution phase peptide synthesis
CN112500450A (zh) * 2019-09-16 2021-03-16 翰宇药业（武汉）有限公司 一种奥曲肽的合成方法
CN112778400A (zh) * 2021-02-05 2021-05-11 合肥科生景肽生物科技有限公司 一种奥曲肽的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE2512T1 (de) * 1979-11-27 1983-03-15 Sandoz Ag Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung.
EP0824103A1 (de) * 1996-08-13 1998-02-18 Chang-Shinn Su Verfahren zur Synthese von Tyr-3-octreotid

Also Published As

Publication number Publication date
EP0953577B1 (de) 2004-03-03
US6346601B1 (en) 2002-02-12
DE69915160T2 (de) 2005-01-20
ES2144357A1 (es) 2000-06-01
ES2144357B1 (es) 2000-12-16
ES2217717T3 (es) 2004-11-01
EP0953577A1 (de) 1999-11-03

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