DE69913390D1 - Methode zur trennung von racemischen mischungen von 5-substituierten 4-hydroxy-2-furanonen - Google Patents

Methode zur trennung von racemischen mischungen von 5-substituierten 4-hydroxy-2-furanonen

Info

Publication number
DE69913390D1
DE69913390D1 DE69913390T DE69913390T DE69913390D1 DE 69913390 D1 DE69913390 D1 DE 69913390D1 DE 69913390 T DE69913390 T DE 69913390T DE 69913390 T DE69913390 T DE 69913390T DE 69913390 D1 DE69913390 D1 DE 69913390D1
Authority
DE
Germany
Prior art keywords
substituted
pure
furanones
hydroxy
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69913390T
Other languages
English (en)
Inventor
Georges Appere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxis Isle of Man Ltd
Original Assignee
Oxis Isle of Man Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxis Isle of Man Ltd filed Critical Oxis Isle of Man Ltd
Application granted granted Critical
Publication of DE69913390D1 publication Critical patent/DE69913390D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
DE69913390T 1999-12-29 1999-12-29 Methode zur trennung von racemischen mischungen von 5-substituierten 4-hydroxy-2-furanonen Expired - Lifetime DE69913390D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1999/002068 WO2001049671A1 (en) 1999-12-29 1999-12-29 Methods for resolving racemic mixtures of 5-substituted 4-hydroxy-2-furanones

Publications (1)

Publication Number Publication Date
DE69913390D1 true DE69913390D1 (de) 2004-01-15

Family

ID=11004950

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69913390T Expired - Lifetime DE69913390D1 (de) 1999-12-29 1999-12-29 Methode zur trennung von racemischen mischungen von 5-substituierten 4-hydroxy-2-furanonen

Country Status (7)

Country Link
US (1) US6613919B2 (de)
EP (1) EP1246811B1 (de)
AT (1) ATE255571T1 (de)
AU (1) AU1676300A (de)
CA (1) CA2406816A1 (de)
DE (1) DE69913390D1 (de)
WO (1) WO2001049671A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB565474A (en) * 1941-12-13 1944-11-13 Nat Oil Prod Co A process of synthesising aldehydes and lactones
GB605444A (en) * 1943-11-27 1948-07-23 Merck & Co Inc Improvements in or relating to the resolution of racemic ª‡-hydroxy-ª‰-ª‰-dimethyl-ª†-butyrolactone
GB773174A (en) * 1954-09-09 1957-04-24 Upjohn Co Resolution of d,l-pantolactone
US3541139A (en) * 1967-10-19 1970-11-17 American Cyanamid Co Resolution of racemic alpha-hydroxy-beta,beta-dimethyl-gamma- butyrolactone
LU66433A1 (de) 1972-11-08 1973-02-01
DK134937C (da) * 1974-01-30 1977-07-11 Basf Ag Fremgangsmade til racematspaltning af pantolacton
JPS51108061A (en) * 1975-03-19 1976-09-25 Asahi Chemical Ind d*ll asukorubinsanno bunriho
FI875602A (fi) * 1986-12-23 1988-06-24 Ciba Geigy Ag Optiskt aktivt tetrahydro-2-furanonderivat saosom miksobicid.
US5504108A (en) * 1990-01-12 1996-04-02 The Ohio State University Research Foundation Optically pure 4-aryl-2-hydroxytetronic acids
JPH07285955A (ja) * 1994-04-21 1995-10-31 Daicel Chem Ind Ltd ５−ヒドロキシ−２（５ｈ）−フラノン誘導体の光学異性体分離法
JPH0940667A (ja) * 1995-07-26 1997-02-10 Mitsui Toatsu Chem Inc ピロリジノン誘導体およびその光学分割方法
DE19535762A1 (de) 1995-09-26 1997-03-27 Basf Ag Verfahren zur Racematspaltung
US6005000A (en) 1996-08-22 1999-12-21 Oxis International, Inc. 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor

Also Published As

Publication number Publication date
AU1676300A (en) 2001-07-16
CA2406816A1 (en) 2001-07-12
EP1246811B1 (de) 2003-12-03
US6613919B2 (en) 2003-09-02
ATE255571T1 (de) 2003-12-15
US20030065196A1 (en) 2003-04-03
WO2001049671A1 (en) 2001-07-12
EP1246811A1 (de) 2002-10-09

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