DE69906625D1 - Arabinosyladenin-Derivative - Google Patents

Arabinosyladenin-Derivative

Info

Publication number
DE69906625D1
DE69906625D1 DE69906625T DE69906625T DE69906625D1 DE 69906625 D1 DE69906625 D1 DE 69906625D1 DE 69906625 T DE69906625 T DE 69906625T DE 69906625 T DE69906625 T DE 69906625T DE 69906625 D1 DE69906625 D1 DE 69906625D1
Authority
DE
Germany
Prior art keywords
virus
ara
present
derivative
ada
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69906625T
Other languages
English (en)
Other versions
DE69906625T2 (de
Inventor
Toshio Yamada
Koichi Yamanishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co Ltd filed Critical Nippon Zoki Pharmaceutical Co Ltd
Publication of DE69906625D1 publication Critical patent/DE69906625D1/de
Application granted granted Critical
Publication of DE69906625T2 publication Critical patent/DE69906625T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69906625T 1998-06-24 1999-06-23 Arabinosyladenin-Derivative Expired - Fee Related DE69906625T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17720998 1998-06-24
JP17720998A JP3619017B2 (ja) 1998-06-24 1998-06-24 新規アラビノシルアデニン誘導体

Publications (2)

Publication Number Publication Date
DE69906625D1 true DE69906625D1 (de) 2003-05-15
DE69906625T2 DE69906625T2 (de) 2004-02-05

Family

ID=16027087

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69906625T Expired - Fee Related DE69906625T2 (de) 1998-06-24 1999-06-23 Arabinosyladenin-Derivative

Country Status (9)

Country Link
US (1) US6242429B1 (de)
EP (1) EP0967220B1 (de)
JP (1) JP3619017B2 (de)
KR (1) KR100624050B1 (de)
CN (1) CN1146573C (de)
AT (1) ATE236923T1 (de)
DE (1) DE69906625T2 (de)
ES (1) ES2196676T3 (de)
TW (1) TW564249B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044763A2 (en) * 1999-02-01 2000-08-03 University Of Virginia Patent Foundation Compositions for treating inflammatory response
EP1420021A1 (de) * 1999-05-25 2004-05-19 The Penn State Research Foundation DNA Methyltransferas-Inhibitoren
JP2003501431A (ja) * 1999-05-25 2003-01-14 ザ ペン ステート リサーチ ファウンデイション Ｄｎａメチル基転移酵素阻害剤
JP4138662B2 (ja) 2002-01-10 2008-08-27 ザ・ペンシルバニア・ステイト・リサーチ・フアウンデイシヨン アルキルジアリールボリネートおよび錯化ジアリールボロン酸を調製するための方法。
CA2486339A1 (en) 2002-05-17 2003-11-27 Neurogen Corporation Substituted ring-fused imidazole derivates: gabaa receptor ligands
KR20040036417A (ko) * 2002-10-25 2004-04-30 정낙신 항암 활성을 갖는 티오뉴클레오시드 유도체 및 이를함유하는 약학적 조성물
WO2006040558A1 (en) * 2004-10-15 2006-04-20 Astrazeneca Ab Substituted adenines and the use thereof
WO2007119624A1 (ja) * 2006-04-13 2007-10-25 National University Corporaton Hokkaido University 抗ヘルペスウイルス活性を有するヌクレオシド誘導体

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5545625A (en) 1978-09-26 1980-03-31 Ajinomoto Co Inc 2-methyl-n6-substituted adenine-arabinoside and its preparation
JPS55160797A (en) * 1979-05-31 1980-12-13 Ajinomoto Co Inc Purine nucleoside derivative
AU575438B2 (en) 1984-10-26 1988-07-28 Warner-Lambert Company N6 - substituted deoxyribose analogues of adenosines
JPS6299395A (ja) 1985-10-25 1987-05-08 Yamasa Shoyu Co Ltd ２−アルキニルアデノシンおよび抗高血圧剤
AU8276187A (en) 1986-10-31 1988-05-25 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
US4843066A (en) 1986-11-27 1989-06-27 Nippon Zoki Pharmaceutical Co., Ltd. Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient
DE3739366A1 (de) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel
GB8712745D0 (en) 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
GB2226027B (en) 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
JPH0725785B2 (ja) 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
ES2095960T3 (es) 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
HUT61567A (en) 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
US5705491A (en) * 1992-10-27 1998-01-06 Nippon Zoki Pharmaceutical Co., Ltd. Adenosine deaminase inhibitor

Also Published As

Publication number Publication date
EP0967220B1 (de) 2003-04-09
ATE236923T1 (de) 2003-04-15
US6242429B1 (en) 2001-06-05
CN1146573C (zh) 2004-04-21
JP3619017B2 (ja) 2005-02-09
KR100624050B1 (ko) 2006-09-19
EP0967220A1 (de) 1999-12-29
ES2196676T3 (es) 2003-12-16
TW564249B (en) 2003-12-01
JP2000007695A (ja) 2000-01-11
DE69906625T2 (de) 2004-02-05
CN1242373A (zh) 2000-01-26
KR20000006339A (ko) 2000-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee