DE69837140D1 - Alginatgele mit verzögerter freisetzung - Google Patents

Alginatgele mit verzögerter freisetzung

Info

Publication number
DE69837140D1
DE69837140D1 DE69837140T DE69837140T DE69837140D1 DE 69837140 D1 DE69837140 D1 DE 69837140D1 DE 69837140 T DE69837140 T DE 69837140T DE 69837140 T DE69837140 T DE 69837140T DE 69837140 D1 DE69837140 D1 DE 69837140D1
Authority
DE
Germany
Prior art keywords
alginatgele
delayed release
sustained
methods
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69837140T
Other languages
English (en)
Other versions
DE69837140T2 (de
Inventor
Merrill Seymour Goldenberg
Alice C Beekman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE69837140D1 publication Critical patent/DE69837140D1/de
Application granted granted Critical
Publication of DE69837140T2 publication Critical patent/DE69837140T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69837140T 1997-04-17 1998-04-14 Alginatgele mit verzögerter freisetzung Expired - Fee Related DE69837140T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US842756 1997-04-17
US08/842,756 US6656508B2 (en) 1997-04-17 1997-04-17 Sustained-release alginate gels
PCT/US1998/007566 WO1998046211A1 (en) 1997-04-17 1998-04-14 Sustained-release alginate gels

Publications (2)

Publication Number Publication Date
DE69837140D1 true DE69837140D1 (de) 2007-04-05
DE69837140T2 DE69837140T2 (de) 2007-11-29

Family

ID=25288180

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837140T Expired - Fee Related DE69837140T2 (de) 1997-04-17 1998-04-14 Alginatgele mit verzögerter freisetzung

Country Status (13)

Country Link
US (1) US6656508B2 (de)
EP (1) EP0975333B1 (de)
JP (1) JP2001524084A (de)
AT (1) ATE354351T1 (de)
AU (1) AU6973498A (de)
CA (1) CA2286092C (de)
DE (1) DE69837140T2 (de)
DK (1) DK0975333T3 (de)
ES (1) ES2283052T3 (de)
PT (1) PT975333E (de)
TW (1) TW577755B (de)
WO (1) WO1998046211A1 (de)
ZA (1) ZA983089B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
US6432449B1 (en) * 1998-05-18 2002-08-13 Amgen Inc. Biodegradable sustained-release alginate gels
AU2003200609B2 (en) * 1998-05-18 2006-02-23 Amgen Inc. Biodegradable sustained-release alginate gels
DE69928472T2 (de) 1998-08-07 2006-08-10 Curis, Inc., Cambridge Stabilisierte pharmazeutische Zusammensetzungen von Hedgehog-Proteinen und deren Verwendung
EP1127578A4 (de) * 1998-10-28 2004-12-15 Sankyo Co Heilmittel für knochenmetabolische abweichungen
JP2002536317A (ja) * 1999-02-03 2002-10-29 パウダージェクト リサーチ リミテッド ヒドロゲル粒子処方物
EP1158961A1 (de) * 1999-03-08 2001-12-05 PowderJect Research Limited Verabreichung von mikroteilchen-formulierungen unter verwendung einer nadellosen spritze zur verzörgerten freigabe bioaktiver verbindungen
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
EP1280521B1 (de) 2000-05-12 2005-07-20 Pharmacia & Upjohn Company LLC Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltieren
EP1541132A1 (de) * 2000-05-12 2005-06-15 Pharmacia & Upjohn Company LLC Impfstoffzusammensetzung und Verfahren zur Herstellung derselben sowie Verfahren zur Impfung von Wirbeltieren
WO2002060410A2 (en) * 2001-01-30 2002-08-08 The Regents Of The University Of Michigan Methods for sustained release local delivery of drugs for ablation of unwanted tissue
CZ20022231A3 (cs) * 2001-06-29 2003-02-12 Sankyo Company Limited Komplex skládající se z osteoklastogenezi inhibujícího faktoru a polysacharidu
JP2003081865A (ja) * 2001-09-12 2003-03-19 Ltt Institute Co Ltd 水不溶性徐放性組成物、その製剤及びその製造方法
US20040005999A1 (en) * 2002-03-07 2004-01-08 Andreasen Kasper Huus Polyamino acid-based particle insulin preparation
US6840196B2 (en) 2002-03-13 2005-01-11 Aspen Pet Products, Inc. Rawhide pet chew
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
US8112400B2 (en) * 2003-12-23 2012-02-07 Texas Instruments Incorporated Method for collecting data from semiconductor equipment
FI116625B (fi) * 2004-01-28 2006-01-13 Macrocrystal Oy Menetelmä proteiinien kiteyttämiseksi hiilihydraattirunkoisilla polymeereillä
US20080058410A1 (en) * 2004-07-23 2008-03-06 Dpi Solutions, Inc. Composition for Stabilizing Vitamin C in Water Phase and Method for Stabilizing C Using Thereof
US8202701B2 (en) * 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
CA2583373C (en) 2004-10-12 2013-09-03 Fmc Biopolymer As Self-gelling alginate systems and uses thereof
US20060099550A1 (en) * 2004-11-10 2006-05-11 Ranir/Dcp Corporation Device and method for delivering an oral care agent
WO2007011743A2 (en) * 2005-07-14 2007-01-25 Lipothera, Inc. Sustained release enhanced lipolytic formulation for regional adipose tissue treatment
US20070116680A1 (en) * 2005-11-18 2007-05-24 Rensselaer Polytechnic Institute Stem cells within gel microenvironments
TWI285100B (en) * 2005-12-27 2007-08-11 Ind Tech Res Inst Surface modification of polysaccharide, the modified polysaccharide, and method of culturing and recovery cells using the same
WO2007146319A2 (en) * 2006-06-13 2007-12-21 Symphony Medical, Inc. Methods and apparatus for using polymer-based beads and hydrogels for cardiac applications
PL2077830T3 (pl) * 2006-10-17 2013-04-30 Lithera Inc Sposoby, kompozycje i formulacje do leczenia orbitopatii tarczycowej
GB0624227D0 (en) * 2006-12-05 2007-01-10 Common Services Agency Protein purification
JP5162134B2 (ja) * 2007-01-22 2013-03-13 愛媛県 機能性材料の製造方法、機能性材料、シート状構造体、及び衛生製品
WO2008118387A2 (en) * 2007-03-23 2008-10-02 Wayne State University Erythrocyte atp-release modulators
CN103463638A (zh) * 2007-08-28 2013-12-25 Fmc有限公司 延迟的自胶凝藻酸盐体系及其应用
ES2639016T3 (es) 2007-11-16 2017-10-25 The Rockefeller University Anticuerpos específicos para la forma protofibrilar de proteína beta-amiloide
CN102438657A (zh) * 2009-03-26 2012-05-02 沃萨乌整形外科公司 鉴别定向药物递送组合物的潜在组分的方法
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
MX2012008171A (es) * 2010-01-15 2012-12-17 Lithera Inc Formulaciones aglomeradas liofilizadas.
US20130184835A1 (en) 2010-07-09 2013-07-18 Board Of Regents Of The Unversity Of Texas System Biodegradable scaffolds
CA2815374A1 (en) 2010-11-24 2012-06-07 Lithera, Inc. Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging
GB201120368D0 (en) 2011-11-24 2012-01-04 Sperm Vital As Methods for the preparation of hydrogels
CN103830266A (zh) * 2013-04-24 2014-06-04 杨亚勤 部分氧化海藻酸钠羧甲基化衍生物的制备方法和应用
WO2017027778A1 (en) 2015-08-13 2017-02-16 Temple University-Of The Commonwealth System Of Higher Education Calcium alginate dosage formulations, and methods of making and using thereof
CN109073649A (zh) 2016-02-10 2018-12-21 新泽西鲁特格斯州立大学 用于诊断和治疗结核分枝杆菌感染的新颖抗lam和抗pim6/lam单克隆抗体
KR102228440B1 (ko) 2016-04-13 2021-03-15 가부시키가이샤 엘에스아이 메디엔스 황산화 다당류를 이용한 면역학적 측정법
WO2018044970A1 (en) 2016-08-31 2018-03-08 University Of Rochester Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
WO2020045162A1 (ja) * 2018-08-30 2020-03-05 学校法人慶應義塾 薬物送達用担体

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2507193A (en) 1949-05-17 1950-05-09 Bristol Lab Inc Penicillin product
US2882203A (en) 1951-06-26 1959-04-14 Novo Terapeutisk Labor As Injectable insulin preparation with protracted effect
US2741573A (en) 1953-12-28 1956-04-10 Abbott Lab Penicillin compositions for intramuscular injection
US3676557A (en) 1971-03-02 1972-07-11 Endo Lab Long-acting narcotic antagonist formulations
JPS5416979B2 (de) 1972-01-08 1979-06-26
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4400391A (en) * 1980-01-09 1983-08-23 The United States Of America As Represented By The Secretary Of Agriculture Controlled release of bioactive materials using alginate gel beads
US4690682A (en) 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4789516A (en) 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4744933A (en) 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
CA1215922A (en) 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4695463A (en) 1985-05-24 1987-09-22 Warner-Lambert Company Delivery system for active ingredients and preparation thereof
GB2186485B (en) * 1986-02-13 1988-09-07 Ethical Pharma Ltd Slow release formulation
US4933185A (en) * 1986-09-24 1990-06-12 Massachusetts Institute Of Technology System for controlled release of biologically active compounds
EP0457837A4 (en) 1989-01-26 1993-09-15 Abbott Biotech, Inc. Stabilization of aqueous-based hydrophobic protein solutions and sustained release vehicle
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5175093A (en) * 1989-11-07 1992-12-29 Lehigh University Bioactive cells immobilized in alginate beads containing voids formed with polyethylene glycol
US5215758A (en) 1991-09-11 1993-06-01 Euroceltique, S.A. Controlled release matrix suppository for pharmaceuticals
US5192802A (en) * 1991-09-25 1993-03-09 Mcneil-Ppc, Inc. Bioadhesive pharmaceutical carrier
WO1993009176A2 (en) * 1991-10-29 1993-05-13 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5656297A (en) 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
US5711968A (en) 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
NZ260909A (en) 1993-07-05 1995-04-27 Takeda Chemical Industries Ltd Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution
US5451411A (en) * 1993-10-15 1995-09-19 University Of Washington Methods and compositions for the oral delivery of therapeutic agents
WO1996000081A1 (en) 1994-06-24 1996-01-04 Immunex Corporation Controlled release polypeptide compositions and methods of treating inflammatory bowel disease
US5629184A (en) 1995-01-25 1997-05-13 Amgen Inc. Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides
AU6242096A (en) 1995-06-27 1997-01-30 Takeda Chemical Industries Ltd. Method of producing sustained-release preparation
US5831017A (en) 1996-01-25 1998-11-03 Eli Lilly And Company Obesity protein analog compounds and formulations thereof
AU1838797A (en) 1996-02-06 1997-08-28 Eli Lilly And Company Obesity protein compounds and formulations thereof

Also Published As

Publication number Publication date
PT975333E (pt) 2007-05-31
WO1998046211A1 (en) 1998-10-22
CA2286092A1 (en) 1998-10-22
US20020001619A1 (en) 2002-01-03
JP2001524084A (ja) 2001-11-27
CA2286092C (en) 2004-12-14
ES2283052T3 (es) 2007-10-16
TW577755B (en) 2004-03-01
US6656508B2 (en) 2003-12-02
AU6973498A (en) 1998-11-11
DK0975333T3 (da) 2007-06-18
EP0975333B1 (de) 2007-02-21
ZA983089B (en) 1998-10-19
EP0975333A1 (de) 2000-02-02
DE69837140T2 (de) 2007-11-29
ATE354351T1 (de) 2007-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee