DE69835202D1 - Ultraschallbilderzeugung für die gewebe-untersuchung durch zersprengung des ultraschall-kontrastmedias mittels hochenergetischen pulsen - Google Patents

Ultraschallbilderzeugung für die gewebe-untersuchung durch zersprengung des ultraschall-kontrastmedias mittels hochenergetischen pulsen

Info

Publication number
DE69835202D1
DE69835202D1 DE69835202T DE69835202T DE69835202D1 DE 69835202 D1 DE69835202 D1 DE 69835202D1 DE 69835202 T DE69835202 T DE 69835202T DE 69835202 T DE69835202 T DE 69835202T DE 69835202 D1 DE69835202 D1 DE 69835202D1
Authority
DE
Germany
Prior art keywords
ultrasonic
prospects
target region
contrast agent
contrast media
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69835202T
Other languages
English (en)
Other versions
DE69835202T2 (de
Inventor
Lars Hoff
Jonny Oestensen
Sigmund Frigstad
Morten Eriksen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Application granted granted Critical
Publication of DE69835202D1 publication Critical patent/DE69835202D1/de
Publication of DE69835202T2 publication Critical patent/DE69835202T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13—Tomography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Acoustics & Sound (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
DE69835202T 1997-04-24 1998-04-24 Ultraschallbilderzeugung für die gewebe-untersuchung durch zersprengung des ultraschall-kontrastmedias mittels hochenergetischen pulsen Expired - Lifetime DE69835202T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9708246.5A GB9708246D0 (en) 1997-04-24 1997-04-24 Improvements in or relating to ultrasound imaging
GB9708246 1997-04-24
US4440897P 1997-04-29 1997-04-29
PCT/GB1998/001217 WO1998047533A1 (en) 1997-04-24 1998-04-24 Ultrasound imaging of tissue perfusion by pulse energy disruption of contrast agent

Publications (2)

Publication Number Publication Date
DE69835202D1 true DE69835202D1 (de) 2006-08-24
DE69835202T2 DE69835202T2 (de) 2007-05-31

Family

ID=26311434

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69835202T Expired - Lifetime DE69835202T2 (de) 1997-04-24 1998-04-24 Ultraschallbilderzeugung für die gewebe-untersuchung durch zersprengung des ultraschall-kontrastmedias mittels hochenergetischen pulsen

Country Status (10)

Country Link
US (1) US6315730B1 (de)
EP (1) EP0977594B1 (de)
JP (1) JP4182191B2 (de)
AT (1) ATE332707T1 (de)
AU (1) AU7219098A (de)
DE (1) DE69835202T2 (de)
ES (1) ES2268770T3 (de)
GB (1) GB9708246D0 (de)
NO (1) NO995148L (de)
WO (1) WO1998047533A1 (de)

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US6353803B1 (en) * 1996-01-18 2002-03-05 Yeda Research And Development Co., Ltd. At The Welzmann Institute Of Science Apparatus for monitoring a system in which a fluid flows
US6553327B2 (en) * 1998-09-16 2003-04-22 Yeda Research & Development Co., Ltd. Apparatus for monitoring a system with time in space and method therefor
JP4473981B2 (ja) * 1999-07-21 2010-06-02 株式会社日立メディコ 超音波診断装置
US6436045B1 (en) 2000-04-27 2002-08-20 Koninklijke Phillips Electronics N.V. User controlled destructive waveform routine for ultrasound systems
JP4128082B2 (ja) * 2000-10-25 2008-07-30 ザ ジョン ピー． ロバーツ リサーチ インスティテュート 血流パラメータを算出する方法及び装置
WO2002056666A2 (en) * 2001-01-19 2002-07-25 Angelsen Bjoern A J A method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue
JP2002209898A (ja) * 2001-01-22 2002-07-30 Toshiba Corp 超音波診断装置
JP2003061959A (ja) * 2001-08-22 2003-03-04 Toshiba Corp 超音波診断装置
US6730036B2 (en) * 2002-02-28 2004-05-04 Koninklijke Philips Electronics, N.V. Ultrasonic imaging to detect coronary artery stenosis at rest
AU2003227122B2 (en) * 2002-05-06 2008-05-01 Uscom Limited Blood flow oxygen measurement system and method
AUPS214502A0 (en) * 2002-05-06 2002-06-06 Uscom Pty Ltd Blood flow oxygen measurement
AUPS335502A0 (en) * 2002-07-03 2002-07-25 Uscom Pty Ltd Pacemaker evaluation method and apparatus
EP1572001A1 (de) 2002-11-29 2005-09-14 Amersham Health AS Ultraschallauflösende methode
JP3683886B2 (ja) * 2002-12-27 2005-08-17 株式会社ワイディ マイオカーディアルブラッドボリュームマップによる血液量解析・表示方法
AU2003900261A0 (en) * 2003-01-22 2003-02-06 Uscom Pty Ltd Method and system for the determination of blood characteristics
JP4706003B2 (ja) * 2003-06-12 2011-06-22 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影画像において補充曲線フィッティングを用いる血流評価法
US8021303B2 (en) * 2003-06-12 2011-09-20 Bracco Research Sa System for extracting morphological information through a perfusion assessment process
US7252638B2 (en) * 2003-06-23 2007-08-07 Siemens Medical Solutions Usa, Inc. Method and system for simultaneously displaying relationships of measurements of features associated with a medical image
WO2005020820A1 (en) * 2003-08-28 2005-03-10 University Of Bern Method and system for determining the absolute perfusion rate of a fluid in an analysis region
JP2005081073A (ja) 2003-09-11 2005-03-31 Toshiba Corp 超音波診断装置
US7658714B2 (en) * 2003-10-31 2010-02-09 Siemens Medical Solutions Usa, Inc. Intelligent ultrasound examination storage system
US8047993B2 (en) * 2004-12-08 2011-11-01 Industrial Technology Research Institute Quantitative non-invasive method for detecting degree of malignancy in tumors and application thereof
AU2005318077B2 (en) * 2004-12-23 2011-11-03 Bracco Suisse S.A. A perfusion assessment method and system based on bolus administration
US7415164B2 (en) * 2005-01-05 2008-08-19 Mitsubishi Electric Research Laboratories, Inc. Modeling scenes in videos using spectral similarity
US20070140973A1 (en) * 2005-12-15 2007-06-21 Bristol-Myers Squibb Pharma Company Contrast agents for myocardium perfusion imaging
DE102006057211B3 (de) * 2006-12-01 2008-03-27 Kompetenzzentrum Medizintechnik Ruhr (Kmr) E.V. Verfahren und Vorrichtung zur kontrastmittelgestützten Perfusionsmessung
JP2008245891A (ja) * 2007-03-30 2008-10-16 Ge Medical Systems Global Technology Co Llc 超音波造影撮影方法および超音波診断装置
US20100132731A1 (en) * 2008-12-01 2010-06-03 Matthew Waitesmith Ergonomic Cosmetic Brush
US8192364B2 (en) * 2009-06-10 2012-06-05 Mayo Foundation For Medical Education And Research Method for assessing vascular disease by quantitatively measuring vaso vasorum
US20110144495A1 (en) * 2009-12-14 2011-06-16 Siemens Medical Solutions Usa, Inc. Perfusion Imaging of a Volume in Medical Diagnostic Ultrasound
DE102014103884A1 (de) 2014-03-21 2015-09-24 Endress + Hauser Flowtec Ag Ultraschallwandler und Ultraschall-Durchflussmessgerät
CA3060579A1 (en) * 2017-05-04 2018-11-08 Gynesonics Inc. Methods for monitoring ablation progress with doppler ultrasound

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US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4718433A (en) 1983-01-27 1988-01-12 Feinstein Steven B Contrast agents for ultrasonic imaging
US5040537A (en) * 1987-11-24 1991-08-20 Hitachi, Ltd. Method and apparatus for the measurement and medical treatment using an ultrasonic wave
US4844882A (en) 1987-12-29 1989-07-04 Molecular Biosystems, Inc. Concentrated stabilized microbubble-type ultrasonic imaging agent
US4957656A (en) 1988-09-14 1990-09-18 Molecular Biosystems, Inc. Continuous sonication method for preparing protein encapsulated microbubbles
GB9003821D0 (en) 1990-02-20 1990-04-18 Danbiosyst Uk Diagnostic aid
US5556610A (en) * 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
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US5235984A (en) * 1992-03-30 1993-08-17 Hewlett-Packard Company On-line acoustic densitometry tool for use with an ultrasonic imaging system
US5678553A (en) * 1994-11-01 1997-10-21 Schering Aktiengesellschaft Ultrasonic processes and circuits for carrying out those processes
US5456257A (en) * 1994-11-23 1995-10-10 Advanced Technology Laboratories, Inc. Ultrasonic detection of contrast agents
US5601086A (en) * 1995-05-12 1997-02-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Beat frequency ultrasonic microsphere contrast agent detection system
US5560364A (en) * 1995-05-12 1996-10-01 The Board Of Regents Of The University Of Nebraska Suspended ultra-sound induced microbubble cavitation imaging
US5833613A (en) * 1996-09-27 1998-11-10 Advanced Technology Laboratories, Inc. Ultrasonic diagnostic imaging with contrast agents
DE69634112T2 (de) * 1995-10-10 2005-12-08 Advanced Technology Laboratories, Inc., Bothell Ultraschall-Bilderzeugung zur Diagnostik mittels Kontrastmitteln
CZ28999A3 (cs) * 1996-08-02 1999-07-14 Nycomed Imaging As Použití kontrastního prostředku
US5735281A (en) * 1996-08-09 1998-04-07 Hewlett-Packard Company Method of enhancing and prolonging the effect of ultrasound contrast agents
EP0977597B1 (de) * 1996-09-11 2003-01-15 Imarx Pharmaceutical Corp. Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
NZ335265A (en) * 1996-10-21 2000-07-28 Nycomed Imaging As Gas containing contrast agents that may be co-administered with vasodilator drugs to enhance differences in return signal intensity from normal and hypoperfused myocardial tissue contrast agents
WO1998018501A2 (en) * 1996-10-28 1998-05-07 Marsden, John, Christopher Improvements in or relating to diagnostic/therapeutic agents

Also Published As

Publication number Publication date
DE69835202T2 (de) 2007-05-31
EP0977594B1 (de) 2006-07-12
JP4182191B2 (ja) 2008-11-19
AU7219098A (en) 1998-11-13
JP2001523997A (ja) 2001-11-27
GB9708246D0 (en) 1997-06-18
NO995148D0 (no) 1999-10-22
WO1998047533A1 (en) 1998-10-29
ATE332707T1 (de) 2006-08-15
NO995148L (no) 1999-10-22
ES2268770T3 (es) 2007-03-16
US6315730B1 (en) 2001-11-13
EP0977594A1 (de) 2000-02-09

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