DE69830185D1 - Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen - Google Patents
Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromenInfo
- Publication number
- DE69830185D1 DE69830185D1 DE69830185T DE69830185T DE69830185D1 DE 69830185 D1 DE69830185 D1 DE 69830185D1 DE 69830185 T DE69830185 T DE 69830185T DE 69830185 T DE69830185 T DE 69830185T DE 69830185 D1 DE69830185 D1 DE 69830185D1
- Authority
- DE
- Germany
- Prior art keywords
- secretin
- autistic
- relationship
- syndromes
- differential diagnostics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2235—Secretins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/645—Secretins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/38—Pediatrics
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4704997P | 1997-05-19 | 1997-05-19 | |
PCT/US1998/010224 WO1998052593A1 (en) | 1997-05-19 | 1998-05-19 | Method for assisting in differential diagnosis and treatment of autistic syndromes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69830185D1 true DE69830185D1 (de) | 2005-06-16 |
Family
ID=21946797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69830185T Expired - Fee Related DE69830185D1 (de) | 1997-05-19 | 1998-05-19 | Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen |
Country Status (8)
Country | Link |
---|---|
US (3) | US6020310A (de) |
EP (1) | EP1019072B1 (de) |
JP (1) | JP2002501616A (de) |
AT (1) | ATE295176T1 (de) |
AU (1) | AU748147B2 (de) |
CA (1) | CA2290556A1 (de) |
DE (1) | DE69830185D1 (de) |
WO (1) | WO1998052593A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6150321A (en) * | 1996-12-12 | 2000-11-21 | Colgate-Palmolive Co. | Chemical linker compositions |
DE69830185D1 (de) * | 1997-05-19 | 2005-06-16 | Repligen Corp | Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen |
US6197746B1 (en) * | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
US6020314A (en) * | 1998-08-11 | 2000-02-01 | Milkhaus Laboratory, Inc. | Methods for treatment of neurological disorders |
DE19902773A1 (de) * | 1999-01-25 | 2000-07-27 | Sertuerner Arzneimittel Gmbh | Anticholestatische Wirksamkeit von Luteolin |
MXPA01008038A (es) * | 1999-02-08 | 2002-04-24 | Johnson 6 Johnson | Derivados anticonvulsionantes utiles en el tratamiento de autismo. |
WO2000068433A2 (en) * | 1999-05-06 | 2000-11-16 | Children's Hospital Of Los Angeles | Autism gene |
AU3641401A (en) | 1999-11-05 | 2001-05-14 | Joseph A. Rogoff | Secretin and secretin pharmaceuticals for treating lactose intolerance |
DE19953339A1 (de) * | 1999-11-05 | 2001-05-17 | Goldham Pharma Gmbh | Secretinfragmente |
US6632429B1 (en) * | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
US6534063B1 (en) | 1999-12-17 | 2003-03-18 | Joan M. Fallon | Methods for treating pervasive development disorders |
WO2001079837A1 (en) * | 2000-04-12 | 2001-10-25 | Repligen Corporation | Methylxanthines in the diagnosis and treatment of autistic disorder |
GB0016441D0 (en) * | 2000-07-04 | 2000-08-23 | Pharmagene Lab Limited | Therapeutic method |
US20070053895A1 (en) | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
US6660831B2 (en) * | 2000-08-14 | 2003-12-09 | Joan M. Fallon | Method for diagnosing and treating dysautonomia and other dysautonomic conditions |
US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
JP2005508338A (ja) * | 2001-10-04 | 2005-03-31 | プロテイン セラピューティクス、インク. | 免疫性疾患を処置するためのガンマグロブリンの使用 |
US8100844B2 (en) * | 2002-04-25 | 2012-01-24 | Ultraflex Systems, Inc. | Ambulating ankle and knee joints with bidirectional dampening and assistance using elastomeric restraint |
WO2004100899A2 (en) * | 2003-05-13 | 2004-11-25 | The Mclean Hospital Corporation | Use of secretin in treatments of disorders associated with the amygdala |
JP2005082490A (ja) * | 2003-09-04 | 2005-03-31 | Kirin Brewery Co Ltd | 脳機能改善剤 |
US7947285B2 (en) * | 2003-12-12 | 2011-05-24 | Fein Seymour H | Methods for preventing post endoscopic retrograde cholangiopancreatography pancreatitis |
US7381698B2 (en) * | 2003-12-12 | 2008-06-03 | Chirhoclin, Inc. | Methods for treatment of acute pancreatitis |
US20060198838A1 (en) * | 2004-09-28 | 2006-09-07 | Fallon Joan M | Combination enzyme for cystic fibrosis |
US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
US20070116695A1 (en) * | 2005-09-21 | 2007-05-24 | Fallon Joan M | Pharmaceutical preparations for attention deficit disorder, attention deficit hyperactivity disorder and other associated disorders |
US8551986B2 (en) * | 2005-12-08 | 2013-10-08 | The Mclean Hospital Corporation | Treatment of sequelae of psychiatric disorders |
US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
US20090324730A1 (en) * | 2008-06-26 | 2009-12-31 | Fallon Joan M | Methods and compositions for the treatment of symptoms of complex regional pain syndrome |
US9320780B2 (en) * | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
EP2318035B1 (de) | 2008-07-01 | 2019-06-12 | Curemark, Llc | Verfahren und zusammensetzungen zur behandlung von symptomen von neurologischen und geistesstörungen |
US10776453B2 (en) * | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
NZ593823A (en) | 2009-01-06 | 2013-09-27 | Curelon Llc | Compositions and methods for the treatment or the prevention of infections by e. coli |
AU2010203709B2 (en) | 2009-01-06 | 2014-05-22 | Galenagen, Llc | Compositions and methods for the treatment or prevention of Staphylococcus Aureus infections and for the Eradication or reduction of Staphylococcus Aureus on surfaces |
US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
US9050276B2 (en) | 2009-06-16 | 2015-06-09 | The Trustees Of Columbia University In The City Of New York | Autism-associated biomarkers and uses thereof |
EP2443259A4 (de) * | 2009-06-16 | 2012-10-10 | Univ Columbia | Biomarker für autismus und verwendungen davon |
WO2011050135A1 (en) | 2009-10-21 | 2011-04-28 | Curemark Llc | Methods and compositions for the prevention and treatment of influenza |
CA2778181A1 (en) | 2009-10-26 | 2011-05-05 | Thomas Julius Borody | Therapy for enteric infections |
RU2460466C2 (ru) * | 2010-10-28 | 2012-09-10 | Федеральное государственное учреждение "Российский научный центр восстановительной медицины и курортологии Федерального агентства по здравоохранению и социальному развитию РФ" (ФГУ "РНЦВМиК Росздрава") | Способ определения уровня нервно-психического развития ребенка первого года жизни |
US8586384B2 (en) * | 2011-04-05 | 2013-11-19 | Olympus Corporation | Method of collecting duodenal specimen to detect upper digestive system disease without using pancreatic or bile stimulant |
US8529547B2 (en) * | 2011-04-05 | 2013-09-10 | Olympus Corporation | Method of collecting specimen and method of diagnosing subject to detect upper digestive system disease |
CN103460045B (zh) | 2011-04-05 | 2016-01-20 | 奥林巴斯株式会社 | 胰脏检查方法及胰脏检查试剂盒 |
DK2701733T3 (da) | 2011-04-21 | 2019-05-27 | Curemark Llc | Forbindelser til behandling af neuropsykiatriske forstyrrelser |
WO2013139861A1 (en) | 2012-03-20 | 2013-09-26 | Luc Montagnier | Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders |
US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
CN105358987A (zh) * | 2013-07-02 | 2016-02-24 | 奥林巴斯株式会社 | 胰腺病标记物检测用十二指肠液试样的确定方法、以及胰腺病标记物的检测方法 |
US11464789B2 (en) | 2018-08-03 | 2022-10-11 | Enterin, Inc. | Aminosterol compositions and methods of using the same for treating schizophrenia |
CN109182577B (zh) * | 2018-09-25 | 2022-03-15 | 深圳市英马诺生物科技有限公司 | 自闭症生物标志物及其应用 |
US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833722A (en) | 1971-03-16 | 1974-09-03 | D Graybill | Method for controlling allergies |
JPS5029005B2 (de) * | 1972-05-08 | 1975-09-19 | ||
US3987014A (en) * | 1974-01-10 | 1976-10-19 | Becton, Dickinson And Company | Secretin intermediates and derivatives |
DE2615229C2 (de) * | 1976-04-08 | 1984-05-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur Herstellung und Reinigung von Sekretin |
US4086220A (en) * | 1976-08-09 | 1978-04-25 | G. D. Searle & Co. | Fragments of secretin |
EP0021184B1 (de) * | 1979-06-13 | 1984-02-08 | Hoechst Aktiengesellschaft | Sekretinpräparate mit verstärkter und protrahierter Wirkung, Verfahren zu ihrer Herstellung sowie Dihydroxybenzoyl-L-tyrosin |
NZ196349A (en) | 1980-03-07 | 1984-08-24 | Interx Research Corp | Enhancement of absorption rate of orally administered polar bioactive agents |
JPS58140024A (ja) * | 1982-02-15 | 1983-08-19 | Eisai Co Ltd | セクレチンの精製方法 |
DE3328793A1 (de) * | 1983-08-10 | 1985-02-28 | Hoechst Ag, 6230 Frankfurt | Herstellung von sekretin |
SE454513B (sv) * | 1985-03-11 | 1988-05-09 | Kabigen Ab | Humant sekretin samt kompositioner innehallande detta |
JPS61277618A (ja) * | 1985-06-04 | 1986-12-08 | Suntory Ltd | 自閉症治療剤 |
US5008251A (en) * | 1986-03-27 | 1991-04-16 | The Regents Of The University Of California | Method of treating autism |
US4994467A (en) * | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
US5094837A (en) * | 1990-01-22 | 1992-03-10 | Wayne State University | Method for use of magnetic resonance imaging to image pancreas using secretin |
US5225407A (en) * | 1990-02-22 | 1993-07-06 | Glaxo Group Limited | 5-HT3 receptor antagonists for the treatment of autism |
US5380872A (en) | 1992-07-14 | 1995-01-10 | Glaxo Inc. | Modulators of cholecystokinin |
DE69426415T2 (de) | 1993-01-29 | 2001-07-26 | Aradigm Corp | Intrapulmonares hormonabgabesystem |
US5527825A (en) * | 1994-04-06 | 1996-06-18 | University Of Arkansas | Method of treating schizophrenia, tourette's syndrome, mania, autism, and obsessive compulsive disorder with inhibitors of brain nitric oxide synthase |
GB9417524D0 (en) | 1994-08-31 | 1994-10-19 | Cortecs Ltd | Pharmaceutical compositions |
US5686311A (en) * | 1995-06-23 | 1997-11-11 | The Children's Mercy Hospital | Diagnosis of autism and treatment therefor |
DE69830185D1 (de) * | 1997-05-19 | 2005-06-16 | Repligen Corp | Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen |
US6197746B1 (en) * | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
FR2767830B1 (fr) | 1997-08-26 | 2000-02-04 | Sod Conseils Rech Applic | Oligonucleotides permettant l'identification de precurseurs d'hormones polypeptidiques amidees |
-
1998
- 1998-05-19 DE DE69830185T patent/DE69830185D1/de not_active Expired - Fee Related
- 1998-05-19 AT AT98924800T patent/ATE295176T1/de not_active IP Right Cessation
- 1998-05-19 CA CA002290556A patent/CA2290556A1/en not_active Abandoned
- 1998-05-19 EP EP98924800A patent/EP1019072B1/de not_active Expired - Lifetime
- 1998-05-19 AU AU76885/98A patent/AU748147B2/en not_active Ceased
- 1998-05-19 JP JP55052798A patent/JP2002501616A/ja not_active Ceased
- 1998-05-19 WO PCT/US1998/010224 patent/WO1998052593A1/en active IP Right Grant
- 1998-05-19 US US09/080,631 patent/US6020310A/en not_active Expired - Fee Related
-
1999
- 1999-11-24 US US09/449,512 patent/US6498143B1/en not_active Expired - Fee Related
-
2002
- 2002-12-20 US US10/327,591 patent/US7091182B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6498143B1 (en) | 2002-12-24 |
AU748147B2 (en) | 2002-05-30 |
AU7688598A (en) | 1998-12-11 |
EP1019072B1 (de) | 2005-05-11 |
JP2002501616A (ja) | 2002-01-15 |
ATE295176T1 (de) | 2005-05-15 |
US6020310A (en) | 2000-02-01 |
EP1019072A1 (de) | 2000-07-19 |
US20040146495A1 (en) | 2004-07-29 |
CA2290556A1 (en) | 1998-11-26 |
EP1019072A4 (de) | 2002-06-19 |
US7091182B2 (en) | 2006-08-15 |
WO1998052593A1 (en) | 1998-11-26 |
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