DE69829173D1 - Membran-sekretierte proteine - Google Patents

Membran-sekretierte proteine

Info

Publication number
DE69829173D1
DE69829173D1 DE69829173T DE69829173T DE69829173D1 DE 69829173 D1 DE69829173 D1 DE 69829173D1 DE 69829173 T DE69829173 T DE 69829173T DE 69829173 T DE69829173 T DE 69829173T DE 69829173 D1 DE69829173 D1 DE 69829173D1
Authority
DE
Germany
Prior art keywords
secreted proteins
membrane
protein
osteoblast
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69829173T
Other languages
English (en)
Other versions
DE69829173T2 (de
Inventor
Naoki Kimura
Tomoko Toyoshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE69829173D1 publication Critical patent/DE69829173D1/de
Application granted granted Critical
Publication of DE69829173T2 publication Critical patent/DE69829173T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/14—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber reciprocates
    • G01F11/18—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber reciprocates for fluent solid material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/28—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement
    • G01F11/36—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement with supply or discharge valves of the rectilinearly-moved slide type
    • G01F11/40—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with stationary measuring chambers having constant volume during measurement with supply or discharge valves of the rectilinearly-moved slide type for fluent solid material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69829173T 1997-04-01 1998-04-01 Membran-sekretierte proteine Expired - Lifetime DE69829173T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9965397 1997-04-01
JP9965397 1997-04-01
PCT/JP1998/001511 WO1998043998A1 (fr) 1997-04-01 1998-04-01 Nouvelle proteine secretee par une membrane

Publications (2)

Publication Number Publication Date
DE69829173D1 true DE69829173D1 (de) 2005-04-07
DE69829173T2 DE69829173T2 (de) 2006-04-13

Family

ID=14253023

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829173T Expired - Lifetime DE69829173T2 (de) 1997-04-01 1998-04-01 Membran-sekretierte proteine

Country Status (11)

Country Link
US (3) US6271366B1 (de)
EP (1) EP0976764B1 (de)
JP (1) JP4135813B2 (de)
KR (1) KR20010005892A (de)
AT (1) ATE290019T1 (de)
AU (1) AU734013B2 (de)
CA (1) CA2284734A1 (de)
DE (1) DE69829173T2 (de)
IL (1) IL132112A0 (de)
TW (1) TW562807B (de)
WO (1) WO1998043998A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627199B1 (en) * 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
US20030096355A1 (en) * 1999-07-09 2003-05-22 Ke Zhang Isolation, identification and characterization of ymkz5, a novel member of the TNF-receptor supergene family
WO2001010908A1 (en) 1999-08-04 2001-02-15 Amgen Inc. Ntr3, a member of the tnf-receptor supergene family
AU783682B2 (en) 1999-08-04 2005-11-24 Amgen, Inc. Fhm, a novel member of the TNF ligand supergene family
AU2001296561A1 (en) * 2000-10-04 2002-04-15 Apoxis, S.A. Tach: new tnf-receptor family nucleic acids and polypeptides
EP1343813A4 (de) * 2000-12-19 2004-11-17 Smithkline Beecham Corp Neue verbindungen
ATE442444T1 (de) 2001-10-13 2009-09-15 Asterion Ltd Glykosylphosphatidylinositolhaltige polypeptide
JP2006094701A (ja) * 2002-09-17 2006-04-13 Chugai Pharmaceut Co Ltd ７ｆ４遺伝子トランスジェニック動物
US7326567B2 (en) * 2003-11-12 2008-02-05 Schering Corporation Plasmid system for multigene expression

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2157387C (en) * 1993-03-04 1998-12-15 David C. Rueger Method and compositions for recombinant osteogenic protein production
WO1994026893A1 (en) * 1993-05-12 1994-11-24 Genetics Institute, Inc. Bmp-10 compositions
JPH07118296A (ja) * 1993-10-22 1995-05-09 Sumitomo Metal Ind Ltd 新規のペプチド
JPH0931098A (ja) * 1995-07-24 1997-02-04 Hoechst Japan Ltd 新規なタンパク質ｈｍｗヒトｍｐ５２

Also Published As

Publication number Publication date
US20020128435A1 (en) 2002-09-12
US7235640B2 (en) 2007-06-26
JP4135813B2 (ja) 2008-08-20
US20040152879A1 (en) 2004-08-05
ATE290019T1 (de) 2005-03-15
EP0976764B1 (de) 2005-03-02
WO1998043998A1 (fr) 1998-10-08
AU6521998A (en) 1998-10-22
KR20010005892A (ko) 2001-01-15
EP0976764A4 (de) 2001-03-21
TW562807B (en) 2003-11-21
US6784284B2 (en) 2004-08-31
AU734013B2 (en) 2001-05-31
IL132112A0 (en) 2001-03-19
DE69829173T2 (de) 2006-04-13
CA2284734A1 (en) 1998-10-08
US6271366B1 (en) 2001-08-07
EP0976764A1 (de) 2000-02-02

Similar Documents

Publication Publication Date Title
Toyomura et al. Three subunit a isoforms of mouse vacuolar H+-ATPase: preferential expression of the a3 isoform during osteoclast differentiation
EP1798239A3 (de) G-Protein-gekoppelte Rezeptoren und deren Verwendung
DK1005540T3 (da) IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
DE69632949D1 (de) Die aktivierung von rezeptoren durch gas6
WO2000075350A3 (en) Nucleic acid sequences encoding proteins involved in fatty acid beta-oxidation and methods of use
ES2145015T3 (es) Proteasas especificas de ubiquitina.
PT101297A (pt) Factores mitogenicos gliais, sua preparacao e utilizacao
ATE389666T1 (de) Hohe expressionsrate von proteinen
EP0701563A4 (de) Gen transfer zur behandlung von bindegewebe eines säugetierwirtes
DE69829173D1 (de) Membran-sekretierte proteine
WO1996015144A3 (en) Chromosome 21 gene marker, compositions and methods using same
ATE266671T1 (de) Nukleinsäuresynthese unter verwendung von mittels licht abspaltbaren schutzgruppen
Engelholm et al. The urokinase plasminogen activator receptor–associated protein/Endo180 Is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis
PT907731E (pt) Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes
PT973794E (pt) Receptores de netrina
AU5799200A (en) Lpl variant therapeutics
DK0724637T3 (da) Kortikotropinfrigørende faktor2-receptorer
ATE282706T1 (de) Gegen pilze gerichtete proteine, dafuer kodierende dna und wirtsorganismen, die diese beinhalten
EA199900522A1 (ru) Полипептиды, кодируемые геном, подобным гену липазы человека, композиции и методы
PT1007559E (pt) Celulas geneticamente modificadas que expressam as proteinas morfogeneticas do osso
NO972063L (no) Isolert BMP-reseptorkinaseprotein, DNA-sekvens, rekombinant ekspresjonsvektor samt vertscelle
WO2002072024A3 (en) Transgenic proteins from multi-gene systems, methods, compositions, uses and the like relating thereto
HUP0102911A2 (hu) Indukálható promóterek
Ihara et al. Identification of interleukin-6 as a factor that induces neurite outgrowth by PC12 cells primed with NGF
AU2002320301A1 (en) Novel pgc-1 isoforms and uses therefor

Legal Events

Date Code Title Description
8364 No opposition during term of opposition