PT907731E - Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes - Google Patents
Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoesInfo
- Publication number
- PT907731E PT907731E PT97908260T PT97908260T PT907731E PT 907731 E PT907731 E PT 907731E PT 97908260 T PT97908260 T PT 97908260T PT 97908260 T PT97908260 T PT 97908260T PT 907731 E PT907731 E PT 907731E
- Authority
- PT
- Portugal
- Prior art keywords
- gabab
- receptor
- proteins
- gabab receptor
- receptors
- Prior art date
Links
- 102000005962 receptors Human genes 0.000 title abstract 10
- 108020003175 receptors Proteins 0.000 title abstract 10
- 229960003692 gamma aminobutyric acid Drugs 0.000 title 1
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 102000006239 metabotropic receptors Human genes 0.000 title 1
- 108020004083 metabotropic receptors Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65571696A | 1996-05-30 | 1996-05-30 | |
| US75609196A | 1996-11-22 | 1996-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT907731E true PT907731E (pt) | 2005-07-29 |
Family
ID=27097014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97908260T PT907731E (pt) | 1996-05-30 | 1997-03-19 | Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0907731B1 (pt) |
| JP (3) | JP4131568B2 (pt) |
| AT (1) | ATE290079T1 (pt) |
| AU (1) | AU2028497A (pt) |
| CA (1) | CA2254862A1 (pt) |
| DE (1) | DE69732631T2 (pt) |
| ES (1) | ES2239352T3 (pt) |
| PT (1) | PT907731E (pt) |
| WO (1) | WO1997046675A1 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9772698A (en) | 1997-10-27 | 1999-05-17 | Astrazeneca Ab | New nucleotide sequences |
| CA2321193A1 (en) * | 1998-02-05 | 1999-08-12 | Merck & Co., Inc. | Novel gabab receptor dna sequences |
| WO1999042580A2 (en) * | 1998-02-20 | 1999-08-26 | Smithkline Beecham Corporation | Gaba receptors and their uses |
| EP0937777A3 (en) * | 1998-02-20 | 1999-11-24 | Smithkline Beecham Plc | GABA receptors and their uses |
| CA2325334A1 (en) * | 1998-04-03 | 1999-10-14 | Nps Pharmaceuticals, Inc. | G-protein fusion receptors and chimeric gabab receptors |
| US7262280B1 (en) | 1998-04-03 | 2007-08-28 | Nps Pharmaceuticals, Inc. | G-protein fusion receptors and constructs encoding same |
| WO1999051636A2 (en) * | 1998-04-03 | 1999-10-14 | Nps Pharmaceuticals, Inc. | Gaba b receptor |
| WO1999058567A1 (en) * | 1998-05-08 | 1999-11-18 | Smithkline Beecham Corporation | GABAB1b RECEPTOR |
| AUPP438498A0 (en) * | 1998-06-29 | 1998-07-23 | Garvan Institute Of Medical Research | Novel Gaba-B receptor |
| EP1109565A4 (en) * | 1998-09-01 | 2004-05-19 | Smithkline Beecham Corp | GABAB1AA RECEPTOR |
| GB9819420D0 (en) | 1998-09-07 | 1998-10-28 | Glaxo Group Ltd | Novel receptor |
| DE69933776T2 (de) * | 1998-09-07 | 2008-01-03 | Glaxo Group Ltd., Greenford | GABA B-REZEPTOR-SUBTYPEN GABA B-R1c UND GABA B-R2 UND DEREN HETERODIMERE |
| GB9906882D0 (en) * | 1999-03-25 | 1999-05-19 | Novartis Ag | Organic compounds |
| SE9901659D0 (sv) | 1999-05-06 | 1999-05-06 | Astra Ab | New methods |
| US20010053849A1 (en) * | 1999-06-16 | 2001-12-20 | Mary Jeanne Kreek | Plural biological sample arrays, and preparation and uses thereof |
| US6787646B1 (en) * | 1999-11-12 | 2004-09-07 | Immusol, Inc. | Tumor suppressor molecules and methods of use |
| DE19955408A1 (de) * | 1999-11-18 | 2001-05-23 | Bayer Ag | GABA-B-Rezeptoren |
| WO2004083855A1 (en) * | 2003-03-19 | 2004-09-30 | Solvo Biotechnology, Inc. | Method for the identification of cells specifically modulating slow inhibition in the neocortex |
| CN102532197A (zh) * | 2010-12-24 | 2012-07-04 | 中国科学院上海药物研究所 | 一类光亲和标记双功能探针分子及其制备方法和应用 |
| CN108588087B (zh) * | 2018-05-16 | 2022-06-03 | 南京农业大学 | 一种提高植物抗病性的基因GmLecRK-R及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU662404B2 (en) * | 1992-05-08 | 1995-08-31 | Novartis Ag | Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids |
-
1997
- 1997-03-19 EP EP97908260A patent/EP0907731B1/en not_active Expired - Lifetime
- 1997-03-19 PT PT97908260T patent/PT907731E/pt unknown
- 1997-03-19 AU AU20284/97A patent/AU2028497A/en not_active Abandoned
- 1997-03-19 JP JP50011898A patent/JP4131568B2/ja not_active Expired - Fee Related
- 1997-03-19 WO PCT/EP1997/001370 patent/WO1997046675A1/en active IP Right Grant
- 1997-03-19 CA CA002254862A patent/CA2254862A1/en not_active Abandoned
- 1997-03-19 DE DE69732631T patent/DE69732631T2/de not_active Expired - Lifetime
- 1997-03-19 ES ES97908260T patent/ES2239352T3/es not_active Expired - Lifetime
- 1997-03-19 AT AT97908260T patent/ATE290079T1/de active
-
2007
- 2007-04-17 JP JP2007108678A patent/JP2007289188A/ja active Pending
- 2007-11-08 JP JP2007291036A patent/JP4202403B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE290079T1 (de) | 2005-03-15 |
| DE69732631D1 (de) | 2005-04-07 |
| CA2254862A1 (en) | 1997-12-11 |
| JP2000515005A (ja) | 2000-11-14 |
| WO1997046675A1 (en) | 1997-12-11 |
| JP2007289188A (ja) | 2007-11-08 |
| ES2239352T3 (es) | 2005-09-16 |
| EP0907731B1 (en) | 2005-03-02 |
| DE69732631T2 (de) | 2005-12-29 |
| JP4131568B2 (ja) | 2008-08-13 |
| AU2028497A (en) | 1998-01-05 |
| JP4202403B2 (ja) | 2008-12-24 |
| JP2008113662A (ja) | 2008-05-22 |
| EP0907731A1 (en) | 1999-04-14 |
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