PT907731E - Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes - Google Patents

Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes

Info

Publication number
PT907731E
PT907731E PT97908260T PT97908260T PT907731E PT 907731 E PT907731 E PT 907731E PT 97908260 T PT97908260 T PT 97908260T PT 97908260 T PT97908260 T PT 97908260T PT 907731 E PT907731 E PT 907731E
Authority
PT
Portugal
Prior art keywords
gabab
receptor
proteins
gabab receptor
receptors
Prior art date
Application number
PT97908260T
Other languages
English (en)
Inventor
Wolfgang Frostl
Helmut Bittiger
Klemens Kaupmann
Bernhard Bettler
Stuart John Mickel
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT907731E publication Critical patent/PT907731E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids R2P(=O)(OH); Thiophosphinic acids, i.e. R2P(=X)(XH) (X = S, Se)
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
PT97908260T 1996-05-30 1997-03-19 Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes PT907731E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65571696A 1996-05-30 1996-05-30
US75609196A 1996-11-22 1996-11-22

Publications (1)

Publication Number Publication Date
PT907731E true PT907731E (pt) 2005-07-29

Family

ID=27097014

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97908260T PT907731E (pt) 1996-05-30 1997-03-19 Receptores gaba[b] metabotropicos, ligandos especificos dos receptores e suas utilizacoes

Country Status (9)

Country Link
EP (1) EP0907731B1 (pt)
JP (3) JP4131568B2 (pt)
AT (1) ATE290079T1 (pt)
AU (1) AU2028497A (pt)
CA (1) CA2254862A1 (pt)
DE (1) DE69732631T2 (pt)
ES (1) ES2239352T3 (pt)
PT (1) PT907731E (pt)
WO (1) WO1997046675A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1027374A1 (en) 1997-10-27 2000-08-16 AstraZeneca AB Nucleotide sequences
CA2321193A1 (en) * 1998-02-05 1999-08-12 Merck & Co., Inc. Novel gabab receptor dna sequences
WO1999042580A2 (en) * 1998-02-20 1999-08-26 Smithkline Beecham Corporation Gaba receptors and their uses
EP0937777A3 (en) * 1998-02-20 1999-11-24 Smithkline Beecham Plc GABA receptors and their uses
WO1999051641A1 (en) * 1998-04-03 1999-10-14 Nps Pharmaceuticals, Inc. G-protein fusion receptors and chimeric gabab receptors
WO1999051636A2 (en) * 1998-04-03 1999-10-14 Nps Pharmaceuticals, Inc. Gaba b receptor
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
WO1999058567A1 (en) * 1998-05-08 1999-11-18 Smithkline Beecham Corporation GABAB1b RECEPTOR
AUPP438498A0 (en) * 1998-06-29 1998-07-23 Garvan Institute Of Medical Research Novel Gaba-B receptor
EP1109565A4 (en) * 1998-09-01 2004-05-19 Smithkline Beecham Corp GABAB1AA RECEPTOR
ATE343634T1 (de) * 1998-09-07 2006-11-15 Glaxo Group Ltd Gaba b-rezeptor-subtypen gaba b-r1c und gaba b-r2 und deren heterodimere
GB9819420D0 (en) 1998-09-07 1998-10-28 Glaxo Group Ltd Novel receptor
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
SE9901659D0 (sv) 1999-05-06 1999-05-06 Astra Ab New methods
US20010053849A1 (en) * 1999-06-16 2001-12-20 Mary Jeanne Kreek Plural biological sample arrays, and preparation and uses thereof
US6787646B1 (en) * 1999-11-12 2004-09-07 Immusol, Inc. Tumor suppressor molecules and methods of use
DE19955408A1 (de) * 1999-11-18 2001-05-23 Bayer Ag GABA-B-Rezeptoren
WO2004083855A1 (en) * 2003-03-19 2004-09-30 Solvo Biotechnology, Inc. Method for the identification of cells specifically modulating slow inhibition in the neocortex
CN102532197A (zh) * 2010-12-24 2012-07-04 中国科学院上海药物研究所 一类光亲和标记双功能探针分子及其制备方法和应用
CN108588087B (zh) * 2018-05-16 2022-06-03 南京农业大学 一种提高植物抗病性的基因GmLecRK-R及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids

Also Published As

Publication number Publication date
DE69732631T2 (de) 2005-12-29
DE69732631D1 (de) 2005-04-07
ATE290079T1 (de) 2005-03-15
ES2239352T3 (es) 2005-09-16
AU2028497A (en) 1998-01-05
EP0907731B1 (en) 2005-03-02
JP2000515005A (ja) 2000-11-14
EP0907731A1 (en) 1999-04-14
CA2254862A1 (en) 1997-12-11
JP2007289188A (ja) 2007-11-08
JP4202403B2 (ja) 2008-12-24
JP2008113662A (ja) 2008-05-22
WO1997046675A1 (en) 1997-12-11
JP4131568B2 (ja) 2008-08-13

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