DE69827814D1 - 8a-AZALIDEN ALS ANTIMIKROBIELLE AGENTEN - Google Patents

8a-AZALIDEN ALS ANTIMIKROBIELLE AGENTEN

Info

Publication number
DE69827814D1
DE69827814D1 DE69827814T DE69827814T DE69827814D1 DE 69827814 D1 DE69827814 D1 DE 69827814D1 DE 69827814 T DE69827814 T DE 69827814T DE 69827814 T DE69827814 T DE 69827814T DE 69827814 D1 DE69827814 D1 DE 69827814D1
Authority
DE
Germany
Prior art keywords
azalides
antimicrobial agents
swine
cattle
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69827814T
Other languages
English (en)
Other versions
DE69827814T2 (de
Inventor
Helmut Kropp
O Farrington
N Clark
W Ratcliffe
D Wilkening
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69827814D1 publication Critical patent/DE69827814D1/de
Publication of DE69827814T2 publication Critical patent/DE69827814T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69827814T 1997-09-10 1998-09-04 8a-Azalide als antimikrobielle Agenten Expired - Lifetime DE69827814T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5832997P 1997-09-10 1997-09-10
US58329P 1997-09-10
GB9806029 1998-03-20
GBGB9806029.6A GB9806029D0 (en) 1998-03-20 1998-03-20 8a-Azalides as veterinary antimicrobial agents
PCT/US1998/018573 WO1999012542A1 (en) 1997-09-10 1998-09-04 8a-AZALIDES AS VETERINARY ANTIMICROBIAL AGENTS

Publications (2)

Publication Number Publication Date
DE69827814D1 true DE69827814D1 (de) 2004-12-30
DE69827814T2 DE69827814T2 (de) 2005-11-24

Family

ID=10828979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69827814T Expired - Lifetime DE69827814T2 (de) 1997-09-10 1998-09-04 8a-Azalide als antimikrobielle Agenten

Country Status (22)

Country Link
EP (2) EP1011664B1 (de)
CN (1) CN1152681C (de)
AT (2) ATE283055T1 (de)
AU (1) AU730172B2 (de)
BR (1) BR9812066A (de)
CA (1) CA2301872C (de)
CZ (1) CZ289868B6 (de)
DE (1) DE69827814T2 (de)
DK (2) DK1011664T3 (de)
EA (1) EA001530B1 (de)
ES (2) ES2376432T3 (de)
GB (1) GB9806029D0 (de)
HU (1) HU228758B1 (de)
IL (1) IL134762A (de)
ME (1) ME00858B (de)
NZ (1) NZ503145A (de)
PL (1) PL192915B1 (de)
PT (2) PT1011664E (de)
RS (1) RS49837B (de)
SI (2) SI1011664T1 (de)
SK (1) SK284791B6 (de)
WO (1) WO1999012542A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2788524B1 (fr) * 1999-01-18 2002-04-26 Merial Sas Procede utile pour transformer la fonction 4"(s)-oh du motif cladinose d'un aza macrolide en 4"(r)-nh2
US6353096B1 (en) 1999-04-01 2002-03-05 Merial Process of use in converting the 4″(S)-OH functional group of the cladinose unit of an azamacrolide to 4″(R)-NH2
GB0025688D0 (en) 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
US20060141054A1 (en) 2004-10-25 2006-06-29 Thomas Piccariello Metal coordinated compositions
US7799937B2 (en) 2004-10-25 2010-09-21 Synthonics, Inc. Metal coordinated compositions
US8779175B2 (en) 2004-10-25 2014-07-15 Synthonics, Inc. Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US20080312167A1 (en) * 2005-05-10 2008-12-18 Sulejman Alihodzic 4'' Amino Linked Macrolides Useful for the Treatment of Microbial Infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281518A (en) * 1986-05-01 1994-01-25 Washington Research Foundation Detection of a unique chlamydia strain associated with acute respiratory disease
GB8726384D0 (en) * 1987-11-11 1987-12-16 Coopers Animal Health Veterinary treatment
US4956294A (en) * 1988-03-07 1990-09-11 Merck & Co., Inc. Culture of Streptoverticillium synroense for producing an antibacterial
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
EP0549040A1 (de) * 1991-12-20 1993-06-30 Merck & Co. Inc. Verfahren zur Herstellung von 4"-Derivaten von 9-Deoxo-8a-Aza-8a-Alkyl-8a-Homoerythromycin A

Also Published As

Publication number Publication date
NZ503145A (en) 2001-02-23
IL134762A (en) 2005-08-31
EA001530B1 (ru) 2001-04-23
EA200000305A1 (ru) 2000-08-28
DK1510214T3 (da) 2012-03-19
CZ2000896A3 (cs) 2000-10-11
BR9812066A (pt) 2000-09-26
YU14700A (sh) 2002-11-15
ME00858B (me) 2008-08-07
ATE535248T1 (de) 2011-12-15
PL339140A1 (en) 2000-12-04
RS49837B (sr) 2008-08-07
SI1510214T1 (sl) 2012-04-30
EP1011664A1 (de) 2000-06-28
SI1011664T1 (en) 2005-02-28
CN1278722A (zh) 2001-01-03
HU228758B1 (en) 2013-05-28
GB9806029D0 (en) 1998-05-20
PL192915B1 (pl) 2006-12-29
AU730172B2 (en) 2001-03-01
DE69827814T2 (de) 2005-11-24
HUP0003845A2 (hu) 2001-08-28
EP1510214A3 (de) 2005-03-23
CN1152681C (zh) 2004-06-09
EP1510214A2 (de) 2005-03-02
EP1510214B1 (de) 2011-11-30
SK284791B6 (sk) 2005-11-03
CZ289868B6 (cs) 2002-04-17
IL134762A0 (en) 2001-04-30
CA2301872A1 (en) 1999-03-18
CA2301872C (en) 2006-12-19
PT1011664E (pt) 2005-02-28
WO1999012542A1 (en) 1999-03-18
PT1510214E (pt) 2012-02-06
ES2376432T3 (es) 2012-03-13
DK1011664T3 (da) 2005-02-14
ES2232964T3 (es) 2005-06-01
HUP0003845A3 (en) 2003-05-28
EP1011664B1 (de) 2004-11-24
SK3222000A3 (en) 2001-01-18
ATE283055T1 (de) 2004-12-15
AU9566498A (en) 1999-03-29
EP1011664A4 (de) 2001-05-16

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