DE69813872D1 - Komplex aus carrageenan und einem wasserlöslichen medikament mit einer spezifischen granulometrie und entsprechende pharmazeutische zusammensetzungen mit gesteuerter freisetzung - Google Patents
Komplex aus carrageenan und einem wasserlöslichen medikament mit einer spezifischen granulometrie und entsprechende pharmazeutische zusammensetzungen mit gesteuerter freisetzungInfo
- Publication number
- DE69813872D1 DE69813872D1 DE69813872T DE69813872T DE69813872D1 DE 69813872 D1 DE69813872 D1 DE 69813872D1 DE 69813872 T DE69813872 T DE 69813872T DE 69813872 T DE69813872 T DE 69813872T DE 69813872 D1 DE69813872 D1 DE 69813872D1
- Authority
- DE
- Germany
- Prior art keywords
- complex
- carrageenan
- pharmaceutical compositions
- controlled release
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229940113118 carrageenan Drugs 0.000 title abstract 3
- 235000010418 carrageenan Nutrition 0.000 title abstract 3
- 229920001525 carrageenan Polymers 0.000 title abstract 3
- 239000000679 carrageenan Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000001033 granulometry Methods 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97PV000009A IT1297461B1 (it) | 1997-10-29 | 1997-10-29 | Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili |
| ITPV970009 | 1997-10-29 | ||
| PCT/EP1998/006864 WO1999021586A2 (en) | 1997-10-29 | 1998-10-29 | Complex between carrageenan and a water soluble drug having a specific granulometry and relative controlled release pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69813872D1 true DE69813872D1 (de) | 2003-05-28 |
| DE69813872T2 DE69813872T2 (de) | 2004-02-26 |
Family
ID=11397386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69813872T Expired - Fee Related DE69813872T2 (de) | 1997-10-29 | 1998-10-29 | Komplex aus carrageenan und einem wasserlöslichen medikament mit einer spezifischen granulometrie und entsprechende pharmazeutische zusammensetzungen mit gesteuerter freisetzung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6355272B1 (de) |
| EP (1) | EP1030689B1 (de) |
| JP (1) | JP2001521010A (de) |
| KR (1) | KR20010031604A (de) |
| AT (1) | ATE238070T1 (de) |
| AU (1) | AU735337B2 (de) |
| BR (1) | BR9813149A (de) |
| CA (1) | CA2307863A1 (de) |
| DE (1) | DE69813872T2 (de) |
| ES (1) | ES2196632T3 (de) |
| IT (1) | IT1297461B1 (de) |
| NZ (1) | NZ504793A (de) |
| WO (1) | WO1999021586A2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| AR034517A1 (es) * | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| US20030229158A1 (en) * | 2001-09-28 | 2003-12-11 | Chen Jen Chi | Polymer composition and dosage forms comprising the same |
| PL374280A1 (en) * | 2001-11-13 | 2005-10-03 | Yamanouchi Pharma Technologies, Inc. | Soluble drug extended release system |
| FR2838349B1 (fr) * | 2002-04-15 | 2004-06-25 | Laurence Paris | Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication |
| US8367098B2 (en) * | 2002-04-30 | 2013-02-05 | The Population Council, Inc. | Unique combinations of antimicrobial compositions |
| AU2003245252A1 (en) * | 2002-04-30 | 2003-11-17 | Fmc Corporation | Carrageenan based antimicrobial compositions |
| SE0201659D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| SE0201661D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| US20040091528A1 (en) * | 2002-11-12 | 2004-05-13 | Yamanouchi Pharma Technologies, Inc. | Soluble drug extended release system |
| ES2336913T3 (es) * | 2003-08-08 | 2010-04-19 | Biovail Laboratories International Srl | Comprimido de liberacion modificada de hidrocloruro de bupropion. |
| CA2601716C (en) * | 2004-06-25 | 2011-05-31 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of attention deficit hyperactivity disorder and hyperphenylalanemia |
| WO2006007354A2 (en) * | 2004-06-28 | 2006-01-19 | Alza Corporation | A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device |
| DE202009018024U1 (de) | 2008-08-01 | 2010-12-09 | Krka Tovarna Zdravil, D.D., Novo Mesto | Quetiapin-Zusammensetzung |
| JP2011068606A (ja) * | 2009-09-25 | 2011-04-07 | Kumamoto Univ | 徐放性担体及び同徐放性担体を用いた薬剤並びに同薬剤を用いたドラッグデリバリーシステム |
| US9474715B2 (en) | 2011-11-30 | 2016-10-25 | Andreas Voigt | Polymeric drug-delivery material, method for manufacturing thereof and method for delivery of a drug-delivery composition |
| US9364549B2 (en) | 2011-11-30 | 2016-06-14 | Andreas Voigt | Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition |
| US20130303632A1 (en) * | 2012-05-10 | 2013-11-14 | Fmc Corporation | Controlled release solid dose form |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5227M (de) | 1966-03-18 | 1967-08-14 | ||
| US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
| SE8204244L (sv) * | 1982-07-09 | 1984-01-10 | Ulf Schroder | Kristalliserad kolhydratsmatris for biologiskt aktiva substanser |
| DK171716B1 (da) | 1982-03-12 | 1997-04-07 | Pharmacia & Upjohn Ab | Fremgangsmåde til fremstilling af et kompleks af carrageenan og emepronium, doxycyklin eller propranolol |
| JPS60174729A (ja) | 1984-02-21 | 1985-09-09 | Nippon Shinyaku Co Ltd | 抗癌医薬組成物 |
| US4613497A (en) * | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
| JPS61130239A (ja) | 1984-11-30 | 1986-06-18 | Dai Ichi Seiyaku Co Ltd | 複合体 |
| FR2618073B1 (fr) * | 1987-07-16 | 1990-09-07 | Pf Medicament | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
| SE9103110D0 (sv) | 1991-10-24 | 1991-10-24 | Kabi Pharmacia Ab | New drug formulation |
-
1997
- 1997-10-29 IT IT97PV000009A patent/IT1297461B1/it active IP Right Grant
-
1998
- 1998-10-29 AT AT98961110T patent/ATE238070T1/de not_active IP Right Cessation
- 1998-10-29 WO PCT/EP1998/006864 patent/WO1999021586A2/en not_active Application Discontinuation
- 1998-10-29 CA CA002307863A patent/CA2307863A1/en not_active Abandoned
- 1998-10-29 US US09/530,245 patent/US6355272B1/en not_active Expired - Fee Related
- 1998-10-29 AU AU16651/99A patent/AU735337B2/en not_active Ceased
- 1998-10-29 NZ NZ504793A patent/NZ504793A/en unknown
- 1998-10-29 DE DE69813872T patent/DE69813872T2/de not_active Expired - Fee Related
- 1998-10-29 KR KR1020007004655A patent/KR20010031604A/ko not_active Application Discontinuation
- 1998-10-29 EP EP98961110A patent/EP1030689B1/de not_active Expired - Lifetime
- 1998-10-29 ES ES98961110T patent/ES2196632T3/es not_active Expired - Lifetime
- 1998-10-29 BR BR9813149-4A patent/BR9813149A/pt not_active IP Right Cessation
- 1998-10-29 JP JP2000517744A patent/JP2001521010A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010031604A (ko) | 2001-04-16 |
| AU1665199A (en) | 1999-05-17 |
| EP1030689B1 (de) | 2003-04-23 |
| IT1297461B1 (it) | 1999-12-17 |
| WO1999021586A3 (en) | 1999-07-08 |
| EP1030689A1 (de) | 2000-08-30 |
| BR9813149A (pt) | 2000-08-15 |
| DE69813872T2 (de) | 2004-02-26 |
| ITPV970009A0 (it) | 1997-10-29 |
| CA2307863A1 (en) | 1999-05-06 |
| JP2001521010A (ja) | 2001-11-06 |
| ITPV970009A1 (it) | 1999-04-29 |
| ES2196632T3 (es) | 2003-12-16 |
| AU735337B2 (en) | 2001-07-05 |
| NZ504793A (en) | 2002-03-01 |
| ATE238070T1 (de) | 2003-05-15 |
| WO1999021586A2 (en) | 1999-05-06 |
| US6355272B1 (en) | 2002-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |