DE69809962T2 - Verfahren zur herstellung von hydroxysubstituierten gamma-butyrolactonen - Google Patents
Verfahren zur herstellung von hydroxysubstituierten gamma-butyrolactonenInfo
- Publication number
- DE69809962T2 DE69809962T2 DE69809962T DE69809962T DE69809962T2 DE 69809962 T2 DE69809962 T2 DE 69809962T2 DE 69809962 T DE69809962 T DE 69809962T DE 69809962 T DE69809962 T DE 69809962T DE 69809962 T2 DE69809962 T2 DE 69809962T2
- Authority
- DE
- Germany
- Prior art keywords
- hydroxy substituted
- preparation
- substituted gamma
- producing hydroxy
- butyrolactones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US962365 | 1997-10-31 | ||
US08/962,365 US5808107A (en) | 1997-10-31 | 1997-10-31 | Process for the preparation of hydroxy substituted gamma butyrolactones |
PCT/US1998/020448 WO1999023086A1 (en) | 1997-10-31 | 1998-09-29 | Process for the preparation of hydroxy substituted gamma butyrolactones |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69809962D1 DE69809962D1 (de) | 2003-01-16 |
DE69809962T2 true DE69809962T2 (de) | 2003-04-24 |
DE69809962T3 DE69809962T3 (de) | 2006-12-14 |
Family
ID=25505755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69809962T Expired - Fee Related DE69809962T3 (de) | 1997-10-31 | 1998-09-29 | Verfahren zur herstellung von hydroxysubstituierten gamma-butyrolactonen |
Country Status (11)
Country | Link |
---|---|
US (2) | US5808107A (de) |
EP (1) | EP1027343B2 (de) |
JP (1) | JP3527706B2 (de) |
KR (1) | KR100369857B1 (de) |
AT (1) | ATE229013T1 (de) |
CA (1) | CA2304809C (de) |
DE (1) | DE69809962T3 (de) |
DK (1) | DK1027343T3 (de) |
ES (1) | ES2188017T5 (de) |
PT (1) | PT1027343E (de) |
WO (1) | WO1999023086A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9618099D0 (en) | 1996-08-30 | 1996-10-09 | Zeneca Ltd | Process |
IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
US6949684B2 (en) | 1998-03-03 | 2005-09-27 | Daiso Co., Ltd. | Process for preparing 1,2,4-butanetriol |
JP3885497B2 (ja) * | 1998-03-03 | 2007-02-21 | ダイソー株式会社 | 1,2,4−ブタントリオールの製造方法 |
US6084131A (en) * | 1998-06-01 | 2000-07-04 | Board Of Trustees Operating Michigan State University | Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof |
US6040464A (en) * | 1998-06-01 | 2000-03-21 | Board Of Trustees Operating Michigan State University | Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof |
US6713290B2 (en) * | 1998-07-24 | 2004-03-30 | Samsung Fine Chemicals Co., Ltd. | Process for preparing optically pure (S)-3-hydroxy-γ-butyrolactone |
CN1316008A (zh) * | 1998-07-24 | 2001-10-03 | 三星精密化学株式会社 | 制备α-(1,4)-连接的寡糖的方法 |
US6423850B1 (en) * | 1999-06-18 | 2002-07-23 | E.I. Du Pont De Nemours And Company | Preparation and use of gamma-butyrolactones as cross-linking agents |
KR100645665B1 (ko) | 2000-07-27 | 2006-11-13 | 에스케이 주식회사 | (s)-베타-하이드록시-감마-부티로락톤의 연속 제조방법 |
US6288239B1 (en) | 2000-09-19 | 2001-09-11 | Board Of Trustees Operating Michigan State University | 5-trityloxymethyl-oxazolidinones and process for the preparation thereof |
US6288238B1 (en) | 2000-09-19 | 2001-09-11 | Board Of Trustees Operating Michigan State University | Process for the preparation of 5-hydroxymethyl 2-oxazolidinone and novel intermediate |
JP4824874B2 (ja) * | 2001-07-19 | 2011-11-30 | 高砂香料工業株式会社 | 光学活性γ−ブチロラクトンの製造方法 |
EP1398312A1 (de) * | 2002-09-13 | 2004-03-17 | Hong-Sun Uh | Beta-substituierte gamma-Butyrolactone und Verfahren ihrer Herstellung |
JP2005539078A (ja) * | 2002-09-18 | 2005-12-22 | エス ケー コーポレイション | 光学的に純粋な(S)−β−ヒドロキシ−γ−ブチロラクトンの連続製造方法 |
WO2005068642A2 (en) | 2003-10-01 | 2005-07-28 | Board Of Trustees Operating Michigan State University | Bacterial synthesis of 1,2,4-butanetriol enantiomers |
CN100335457C (zh) * | 2005-09-08 | 2007-09-05 | 上海交通大学 | 3-位手性羟基被保护的3,4-二羟基丁酸酯及其制备方法 |
US20090104669A1 (en) * | 2006-03-02 | 2009-04-23 | Oh-Jin Park | Method for Preparing (S)-3-Hydroxy-Gamma-Butyrolactone Using Hydrolase |
US20110165641A1 (en) * | 2006-03-31 | 2011-07-07 | The Board Of Trustees Of Michigan State University | Synthesis of 1,2,4-Butanetriol Enantiomers from Carbohydrates |
US20110076730A1 (en) * | 2006-07-19 | 2011-03-31 | Board Of Trustees Of Michigan State University | Microbial synthesis of d-1,2,4-butanetriol |
CN100441573C (zh) * | 2006-07-20 | 2008-12-10 | 厦门大学 | 一种合成s-(3)-羟基四氢呋喃的方法 |
US8361760B2 (en) * | 2009-03-06 | 2013-01-29 | Massachusetts Institute Of Technology | Microbial production of 3-hydroxyacids from glucose and glycolate |
WO2012116307A1 (en) | 2011-02-25 | 2012-08-30 | Massachusetts Institute Of Technology | Microbial production of 3,4-dihydroxybutyrate (3,4-dhba), 2,3-dihydroxybutyrate (2,3-dhba) and 3-hydroxybutyrolactone (3-hbl) |
MX2018010466A (es) * | 2016-03-15 | 2019-01-14 | Shionogi & Co | Metodo de produccion para derivados de fenoxietanol. |
IL275312B1 (en) | 2017-12-18 | 2024-05-01 | Tris Pharma Inc | GHB pharmacy preparations containing a system that creates a floating integrated penetrating polymer network |
US11337919B2 (en) | 2017-12-18 | 2022-05-24 | Tris Pharma, Inc. | Modified release drug powder composition comprising gastro-retentive RAFT forming systems having trigger pulse drug release |
WO2019126214A1 (en) | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Pharmaceutical composition comprising ghb gastro-retentive raft forming systems having trigger pulse drug release |
FR3088324B1 (fr) * | 2018-11-08 | 2020-10-09 | Inst Des Sciences Et Industries Du Vivant Et De Lenvironnement Agroparistech | Procede biocatalytique de production de 2h-hbo a partir de lgo utilisant une cyclohexanone monooxygenase |
CN112939901B (zh) * | 2021-02-09 | 2023-05-09 | 中国科学院福建物质结构研究所 | 一种α-羟基-γ-丁内酯的制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3024250A (en) * | 1962-03-06 | Certificate of correction | ||
US2683721A (en) * | 1952-01-17 | 1954-07-13 | Hermann I Schlesinger | Method of reducing and hydrogenating chemical compounds by reacting with alkali metal borohydrides |
US3997569A (en) * | 1972-11-08 | 1976-12-14 | Texaco Inc. | Method for preparing a lactone reaction product |
US3868370A (en) * | 1973-02-09 | 1975-02-25 | Gen Electric | Process for making 4-butyrolactone |
US4083809A (en) * | 1976-08-20 | 1978-04-11 | Gaf Corporation | Hydrogenation catalyst and method of producing same |
GB1587198A (en) * | 1976-11-23 | 1981-04-01 | Ucb Sa | Process for the production of butane-1,4 diol and tetrahydrofuran |
US4772729A (en) * | 1987-01-23 | 1988-09-20 | E. I. Du Pont De Nemours And Company | Hydrogenation of citric acid and substituted citric acids to 3-substituted tetrahydrofuran, 3- and 4-substituted butyrolactones and mixtures thereof |
DE3870543D1 (de) * | 1987-08-08 | 1992-06-04 | Basf Ag | Verfahren zur herstellung von 1,4-butandiol und/oder tetrahydrofuran. |
US5087751A (en) * | 1988-04-27 | 1992-02-11 | Kanegafuchi Kagaku Kogyo K.K. | Method of preparing optically active 3,4-dihydroxy butyric acid derivatives |
CA1307796C (en) * | 1988-04-27 | 1992-09-22 | Kenji Inoue | Method for preparing optically active 3,4-dihydroxy butyric acid derivatives |
CA2049536C (en) * | 1991-05-13 | 1999-07-06 | Rawle I. Hollingsworth | Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof |
DE69225560T2 (de) * | 1991-11-18 | 1998-11-12 | Tosoh Corp | Verfahren zur Herstellung von Lactonen |
GB9618099D0 (en) † | 1996-08-30 | 1996-10-09 | Zeneca Ltd | Process |
-
1997
- 1997-10-31 US US08/962,365 patent/US5808107A/en not_active Ceased
-
1998
- 1998-09-29 CA CA002304809A patent/CA2304809C/en not_active Expired - Fee Related
- 1998-09-29 PT PT98948584T patent/PT1027343E/pt unknown
- 1998-09-29 WO PCT/US1998/020448 patent/WO1999023086A1/en active IP Right Grant
- 1998-09-29 DE DE69809962T patent/DE69809962T3/de not_active Expired - Fee Related
- 1998-09-29 EP EP98948584A patent/EP1027343B2/de not_active Expired - Lifetime
- 1998-09-29 ES ES98948584T patent/ES2188017T5/es not_active Expired - Lifetime
- 1998-09-29 KR KR10-2000-7004510A patent/KR100369857B1/ko not_active IP Right Cessation
- 1998-09-29 JP JP2000518957A patent/JP3527706B2/ja not_active Expired - Fee Related
- 1998-09-29 AT AT98948584T patent/ATE229013T1/de not_active IP Right Cessation
- 1998-09-29 DK DK98948584T patent/DK1027343T3/da active
-
2002
- 2002-03-28 US US10/109,487 patent/USRE38324E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1027343A1 (de) | 2000-08-16 |
WO1999023086A1 (en) | 1999-05-14 |
EP1027343B2 (de) | 2006-01-11 |
DE69809962T3 (de) | 2006-12-14 |
JP3527706B2 (ja) | 2004-05-17 |
CA2304809C (en) | 2006-08-01 |
CA2304809A1 (en) | 1999-05-14 |
ATE229013T1 (de) | 2002-12-15 |
DE69809962D1 (de) | 2003-01-16 |
KR20010031475A (ko) | 2001-04-16 |
ES2188017T5 (es) | 2006-07-16 |
ES2188017T3 (es) | 2003-06-16 |
EP1027343B1 (de) | 2002-12-04 |
DK1027343T3 (da) | 2003-03-31 |
JP2001521931A (ja) | 2001-11-13 |
US5808107A (en) | 1998-09-15 |
KR100369857B1 (ko) | 2003-02-05 |
USRE38324E1 (en) | 2003-11-18 |
PT1027343E (pt) | 2003-04-30 |
EP1027343A4 (de) | 2001-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings | ||
8339 | Ceased/non-payment of the annual fee |