DE69806270T2 - Wasserfreies reservoir für gerät zur transdermalen elektrolytischen medikamentverabreichung - Google Patents
Wasserfreies reservoir für gerät zur transdermalen elektrolytischen medikamentverabreichungInfo
- Publication number
- DE69806270T2 DE69806270T2 DE69806270T DE69806270T DE69806270T2 DE 69806270 T2 DE69806270 T2 DE 69806270T2 DE 69806270 T DE69806270 T DE 69806270T DE 69806270 T DE69806270 T DE 69806270T DE 69806270 T2 DE69806270 T2 DE 69806270T2
- Authority
- DE
- Germany
- Prior art keywords
- transdermal
- electrolytic
- water
- solvent
- filtration membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0444—Membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7125697P | 1997-12-22 | 1997-12-22 | |
PCT/US1998/026778 WO1999032190A1 (en) | 1997-12-22 | 1998-12-16 | Anhydrous drug reservoir for electrolytic transdermal delivery device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69806270D1 DE69806270D1 (de) | 2002-08-01 |
DE69806270T2 true DE69806270T2 (de) | 2002-10-10 |
Family
ID=22100218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69806270T Expired - Lifetime DE69806270T2 (de) | 1997-12-22 | 1998-12-16 | Wasserfreies reservoir für gerät zur transdermalen elektrolytischen medikamentverabreichung |
Country Status (12)
Country | Link |
---|---|
US (2) | US6374136B1 (de) |
EP (1) | EP1049515B1 (de) |
JP (1) | JP4183909B2 (de) |
KR (1) | KR100601776B1 (de) |
CN (1) | CN1282263A (de) |
AT (1) | ATE219696T1 (de) |
AU (1) | AU2199999A (de) |
CA (1) | CA2315659A1 (de) |
DE (1) | DE69806270T2 (de) |
ES (1) | ES2179552T3 (de) |
HK (1) | HK1032548A1 (de) |
WO (1) | WO1999032190A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000061218A1 (fr) * | 1999-04-12 | 2000-10-19 | Hisamitsu Pharmaceutical Co., Inc. | Dispositif d'iontophorese et procede d'application de courant |
JP4033382B2 (ja) * | 2002-04-08 | 2008-01-16 | 久光製薬株式会社 | インスリン投与装置 |
ES2336214T3 (es) * | 2003-10-27 | 2010-04-09 | Universitat Basel | Sistema de suministro transdermico de farmacos. |
US8758593B2 (en) * | 2004-01-08 | 2014-06-24 | Schlumberger Technology Corporation | Electrochemical sensor |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
WO2006031856A2 (en) * | 2004-09-13 | 2006-03-23 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
US7590444B2 (en) * | 2004-12-09 | 2009-09-15 | Tti Ellebeau, Inc. | Iontophoresis device |
US20070042026A1 (en) * | 2005-03-17 | 2007-02-22 | Wille John J | Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions |
US8372040B2 (en) | 2005-05-24 | 2013-02-12 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
JP2008543359A (ja) * | 2005-06-10 | 2008-12-04 | トランスファーマ メディカル,リミティド | 経皮投薬用のパッチ |
TWI419717B (zh) * | 2005-06-17 | 2013-12-21 | Altea Therapeutics Corp | 滲透傳送系統及其使用方法 |
JP2006346368A (ja) * | 2005-06-20 | 2006-12-28 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその製造方法 |
US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
US20090214625A1 (en) * | 2005-07-15 | 2009-08-27 | Mizuo Nakayama | Drug delivery patch |
JP2007037868A (ja) * | 2005-08-05 | 2007-02-15 | Transcutaneous Technologies Inc | 経皮投与装置及びその制御方法 |
US8386030B2 (en) * | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
US20070060860A1 (en) * | 2005-08-18 | 2007-03-15 | Transcutaneous Technologies Inc. | Iontophoresis device |
US20100016781A1 (en) * | 2005-08-29 | 2010-01-21 | Mizuo Nakayama | Iontophoresis device selecting drug to be administered on the basis of information form sensor |
JPWO2007029611A1 (ja) * | 2005-09-06 | 2009-03-19 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
CN101262905A (zh) * | 2005-09-16 | 2008-09-10 | Tti优而美株式会社 | 探针式离子电渗疗装置 |
WO2007037324A1 (ja) * | 2005-09-28 | 2007-04-05 | Transcu Ltd. | 乾燥型イオントフォレーシス用電極構造体 |
WO2007037475A1 (ja) * | 2005-09-30 | 2007-04-05 | Tti Ellebeau, Inc. | 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置 |
WO2007037476A1 (ja) * | 2005-09-30 | 2007-04-05 | Tti Ellebeau, Inc. | 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置 |
JP2009509657A (ja) * | 2005-09-30 | 2009-03-12 | Tti・エルビュー株式会社 | 生体界面への活性物質の送達のイオントフォレーシス装置及び方法 |
CN101277737A (zh) * | 2005-09-30 | 2008-10-01 | Tti优而美株式会社 | 将多种活性剂输送至生物界面的离子电渗装置 |
US20070197955A1 (en) * | 2005-10-12 | 2007-08-23 | Transcutaneous Technologies Inc. | Mucous membrane adhesion-type iontophoresis device |
JP4804904B2 (ja) * | 2005-12-09 | 2011-11-02 | Tti・エルビュー株式会社 | イオントフォレーシス装置包装品 |
JP2007175117A (ja) * | 2005-12-27 | 2007-07-12 | Hisamitsu Pharmaceut Co Inc | イオントフォレーシス装置及びその製造方法 |
US20080033338A1 (en) * | 2005-12-28 | 2008-02-07 | Smith Gregory A | Electroosmotic pump apparatus and method to deliver active agents to biological interfaces |
WO2007092101A2 (en) * | 2005-12-29 | 2007-08-16 | Boston Scientific Limited | Foam electrode for tissue resection |
US20080033398A1 (en) * | 2005-12-29 | 2008-02-07 | Transcutaneous Technologies Inc. | Device and method for enhancing immune response by electrical stimulation |
US7848801B2 (en) * | 2005-12-30 | 2010-12-07 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
WO2007123707A1 (en) * | 2006-03-30 | 2007-11-01 | Tti Ellebeau, Inc. | Controlled release membrane and methods of use |
US20080009782A1 (en) * | 2006-06-28 | 2008-01-10 | Alza Corporation | Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil |
US20080004671A1 (en) * | 2006-06-28 | 2008-01-03 | Alza Corporation | Vagus nerve stimulation via orally delivered apparatus |
CN101495105A (zh) * | 2006-07-05 | 2009-07-29 | Tti优而美株式会社 | 具有自组装树枝状聚合物的输送装置及其使用方法 |
WO2008013913A2 (en) * | 2006-07-26 | 2008-01-31 | Aciont, Inc. | Method and device for minimally invasive site specific ocular drug delivery |
JP2010502293A (ja) * | 2006-09-05 | 2010-01-28 | Tti・エルビュー株式会社 | 誘導型電源を用いる経皮薬物送達システム、装置及び方法 |
JP5383497B2 (ja) * | 2006-12-01 | 2014-01-08 | Tti・エルビュー株式会社 | 装置、例として経皮送達装置に給電し且つ/又は当該装置を制御するシステム及び装置 |
US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
WO2009050718A2 (en) * | 2007-10-17 | 2009-04-23 | Transpharma Medical Ltd. | Dissolution rate verification |
US20100293807A1 (en) * | 2007-10-29 | 2010-11-25 | Transpharma Medical, Ltd. | Vertical patch drying |
FR2924349B1 (fr) | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
FR2926466B1 (fr) * | 2008-01-23 | 2010-11-12 | Dbv Tech | Procede de fabrication de patchs par electrospray |
CA2736495A1 (en) * | 2008-09-10 | 2010-03-18 | Gregory A. Smith | Apparatus and method to dispense hpc-based viscous liquids into porous substrates, e.g., continuous web-based process |
CA2760467A1 (en) * | 2009-05-08 | 2010-11-11 | Isis Biopolymer, Inc. | Iontophoretic device with improved counterelectrode |
US20110092881A1 (en) * | 2009-05-08 | 2011-04-21 | Isis Biopolymer Inc. | Iontophoretic device with contact sensor |
US20100312168A1 (en) * | 2009-06-09 | 2010-12-09 | Yoshimasa Yoshida | Long life high capacity electrode, device, and method of manufacture |
CA2841785A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
CA2974324A1 (en) | 2015-01-28 | 2016-08-04 | Zita S. Netzel | Drug delivery methods and systems |
JP2018511127A (ja) | 2015-03-12 | 2018-04-19 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 渇望入力及び支援システム |
WO2017069910A2 (en) * | 2015-09-25 | 2017-04-27 | Massachusetts Institute Of Technology | Stretchable, robust and biocompatible hydrogel electronics and devices |
WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
US11633587B2 (en) * | 2018-04-10 | 2023-04-25 | Battelle Memorial Institute | Mixed ionic electronic conductors: devices, systems and methods of use |
US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
TW202014215A (zh) * | 2018-10-03 | 2020-04-16 | 拓金造物股份有限公司 | 發電膜片及具有發電膜片的皮膚敷材 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE399044A (de) | 1933-09-09 | |||
US3991755A (en) | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
US4141359A (en) | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
US4250878A (en) | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
WO1981000964A1 (en) | 1979-10-10 | 1981-04-16 | Cyclotech Med Ind | Pain blocking bandage |
US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
JPS5810066A (ja) | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
CA1262564A (en) | 1983-09-01 | 1989-10-31 | Minoru Sasaki | Iontophoresis device |
JPS63102768A (ja) | 1986-10-20 | 1988-05-07 | 山之内製薬株式会社 | イオントフオレ−シス用の新規プラスタ−構造体 |
US4731049A (en) | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
US4940456A (en) | 1987-02-10 | 1990-07-10 | Dan Sibalis | Electrolytic transdermal delivery of proteins |
US4878892A (en) | 1987-02-10 | 1989-11-07 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of polypeptides |
US5080646A (en) * | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US4878893A (en) | 1988-04-28 | 1989-11-07 | Thomas J. Fogarty | Angioscope with flush solution deflector shield |
US5496266A (en) * | 1990-04-30 | 1996-03-05 | Alza Corporation | Device and method of iontophoretic drug delivery |
US4927408A (en) * | 1988-10-03 | 1990-05-22 | Alza Corporation | Electrotransport transdermal system |
EP0555375B2 (de) | 1990-10-29 | 1999-02-03 | Alza Corporation | Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben |
US5158537A (en) | 1990-10-29 | 1992-10-27 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
US5443727A (en) * | 1990-10-30 | 1995-08-22 | Minnesota Mining And Manufacturing Company | Articles having a polymeric shell and method for preparing same |
US5464387A (en) * | 1991-07-24 | 1995-11-07 | Alza Corporation | Transdermal delivery device |
IL105073A0 (en) | 1992-03-17 | 1993-07-08 | Becton Dickinson Co | User activated iontophoretic device and method for using same |
US5310404A (en) * | 1992-06-01 | 1994-05-10 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
US5533971A (en) * | 1993-09-03 | 1996-07-09 | Alza Corporation | Reduction of skin irritation during electrotransport |
US5503632A (en) * | 1994-04-08 | 1996-04-02 | Alza Corporation | Electrotransport device having improved cathodic electrode assembly |
ES2153485T3 (es) * | 1994-07-13 | 2001-03-01 | Alza Corp | Composicion y procedimiento que incrementa la difusion percutanea por electrotransporte de una substancia. |
WO1996005884A1 (en) | 1994-08-22 | 1996-02-29 | Iomed, Inc. | Iontophoretic delivery device with integral hydrating means |
US5736580A (en) * | 1994-11-14 | 1998-04-07 | Alza Croporation | Composition, device, and method for electrotransport agent delivery |
US5624415A (en) * | 1995-04-24 | 1997-04-29 | Alza Corporation | Reduction of skin irritation and resistance during electrotransport |
US5645527A (en) * | 1996-02-09 | 1997-07-08 | Iomed, Inc. | Hydration assembly for hydrating a bioelectrode element |
CA2208336A1 (en) * | 1996-06-20 | 1997-12-20 | Hisamitsu Pharmaceuticals Co., Inc. | A device structure for iontophoresis |
-
1998
- 1998-12-09 US US09/208,808 patent/US6374136B1/en not_active Expired - Lifetime
- 1998-12-16 CN CN98812396A patent/CN1282263A/zh active Pending
- 1998-12-16 AT AT98965997T patent/ATE219696T1/de not_active IP Right Cessation
- 1998-12-16 AU AU21999/99A patent/AU2199999A/en not_active Abandoned
- 1998-12-16 JP JP2000525176A patent/JP4183909B2/ja not_active Expired - Fee Related
- 1998-12-16 WO PCT/US1998/026778 patent/WO1999032190A1/en active IP Right Grant
- 1998-12-16 DE DE69806270T patent/DE69806270T2/de not_active Expired - Lifetime
- 1998-12-16 ES ES98965997T patent/ES2179552T3/es not_active Expired - Lifetime
- 1998-12-16 KR KR1020007007007A patent/KR100601776B1/ko not_active IP Right Cessation
- 1998-12-16 CA CA002315659A patent/CA2315659A1/en not_active Abandoned
- 1998-12-16 EP EP98965997A patent/EP1049515B1/de not_active Expired - Lifetime
-
2001
- 2001-05-07 HK HK01103211A patent/HK1032548A1/xx not_active IP Right Cessation
-
2002
- 2002-01-08 US US10/042,508 patent/US20020058903A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR100601776B1 (ko) | 2006-07-19 |
DE69806270D1 (de) | 2002-08-01 |
KR20010033506A (ko) | 2001-04-25 |
ATE219696T1 (de) | 2002-07-15 |
CA2315659A1 (en) | 1999-07-01 |
US20020058903A1 (en) | 2002-05-16 |
EP1049515A1 (de) | 2000-11-08 |
JP2001526099A (ja) | 2001-12-18 |
AU2199999A (en) | 1999-07-12 |
HK1032548A1 (en) | 2001-07-27 |
WO1999032190A1 (en) | 1999-07-01 |
US6374136B1 (en) | 2002-04-16 |
JP4183909B2 (ja) | 2008-11-19 |
EP1049515B1 (de) | 2002-06-26 |
CN1282263A (zh) | 2001-01-31 |
ES2179552T3 (es) | 2003-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: ALZA CORP., MOUNTAIN VIEW, CALIF., US |