DE69805831D1 - 1,4-disubstituierte cyclohexan-derivate als liganden der 5ht1a rezeptoren - Google Patents
1,4-disubstituierte cyclohexan-derivate als liganden der 5ht1a rezeptorenInfo
- Publication number
- DE69805831D1 DE69805831D1 DE69805831T DE69805831T DE69805831D1 DE 69805831 D1 DE69805831 D1 DE 69805831D1 DE 69805831 T DE69805831 T DE 69805831T DE 69805831 T DE69805831 T DE 69805831T DE 69805831 D1 DE69805831 D1 DE 69805831D1
- Authority
- DE
- Germany
- Prior art keywords
- triazine
- cyclohexane derivatives
- concerns
- ligands
- dioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9712954A FR2769913B1 (fr) | 1997-10-16 | 1997-10-16 | Nouveaux derives cyclohexaniques difonctionnalises en 1, 4, leur preparation et leur application therapeutique humaine |
PCT/FR1998/002207 WO1999020613A1 (fr) | 1997-10-16 | 1998-10-14 | Derives cyclohexaniques difonctionnalises en 1,4, en tant que ligands des recepteurs 5ht1a |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69805831D1 true DE69805831D1 (de) | 2002-07-11 |
DE69805831T2 DE69805831T2 (de) | 2003-01-23 |
Family
ID=9512297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69805831T Expired - Lifetime DE69805831T2 (de) | 1997-10-16 | 1998-10-14 | 1,4-disubstituierte cyclohexan-derivate als liganden der 5ht1a rezeptoren |
Country Status (14)
Country | Link |
---|---|
US (1) | US6191130B1 (de) |
EP (1) | EP1023273B1 (de) |
JP (1) | JP4454848B2 (de) |
CN (1) | CN1127490C (de) |
AT (1) | ATE218553T1 (de) |
AU (1) | AU737178B2 (de) |
BR (1) | BR9812939B1 (de) |
CA (1) | CA2306429C (de) |
DE (1) | DE69805831T2 (de) |
DK (1) | DK1023273T3 (de) |
ES (1) | ES2177064T3 (de) |
FR (1) | FR2769913B1 (de) |
PT (1) | PT1023273E (de) |
WO (1) | WO1999020613A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11307553A (ja) * | 1998-04-21 | 1999-11-05 | Shinkawa Ltd | 半導体ペレットの位置決め方法及びその装置 |
PA8802101A1 (es) * | 2007-11-02 | 2009-08-26 | Abbott Gmbh & Co Kg | Compuestos de 1,2,4-3,5-diona adecuados para el tratamiento de trastornos que responden a la modulación del receptor de dopamina d3 |
GB201017345D0 (en) * | 2010-10-14 | 2010-11-24 | Proximagen Ltd | Receptor antagonists |
WO2014025993A1 (en) * | 2012-08-08 | 2014-02-13 | The Johns Hopkins University | Inhibitors of d-amino acid oxidase |
ES2826558T3 (es) | 2015-04-02 | 2021-05-18 | Proximagen Llc | Nuevas terapias para el cáncer |
CN111454250B (zh) * | 2019-01-21 | 2021-05-07 | 华东理工大学 | 多靶点活性化合物及其用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2707294B1 (fr) * | 1993-07-06 | 1995-09-29 | Pf Medicament | Nouveaux dérivés de la 3,5-dioxo-(2H,4H)-1,2,4-triazine, leur préparation et leur application en thérapeutique humaine. |
FR2727682A1 (fr) * | 1994-12-02 | 1996-06-07 | Pf Medicament | Nouveaux derives de 3,5-dioxo-(2h,4h)-1,2,4-triazines, leur preparation et leur application a titre de medicament |
-
1997
- 1997-10-16 FR FR9712954A patent/FR2769913B1/fr not_active Expired - Fee Related
-
1998
- 1998-10-14 US US09/529,783 patent/US6191130B1/en not_active Expired - Lifetime
- 1998-10-14 CA CA2306429A patent/CA2306429C/fr not_active Expired - Fee Related
- 1998-10-14 EP EP98949063A patent/EP1023273B1/de not_active Expired - Lifetime
- 1998-10-14 AT AT98949063T patent/ATE218553T1/de active
- 1998-10-14 CN CN98811038A patent/CN1127490C/zh not_active Expired - Fee Related
- 1998-10-14 PT PT98949063T patent/PT1023273E/pt unknown
- 1998-10-14 BR BRPI9812939-2A patent/BR9812939B1/pt not_active IP Right Cessation
- 1998-10-14 JP JP2000516955A patent/JP4454848B2/ja not_active Expired - Fee Related
- 1998-10-14 AU AU95458/98A patent/AU737178B2/en not_active Ceased
- 1998-10-14 DK DK98949063T patent/DK1023273T3/da active
- 1998-10-14 ES ES98949063T patent/ES2177064T3/es not_active Expired - Lifetime
- 1998-10-14 DE DE69805831T patent/DE69805831T2/de not_active Expired - Lifetime
- 1998-10-14 WO PCT/FR1998/002207 patent/WO1999020613A1/fr active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
FR2769913A1 (fr) | 1999-04-23 |
AU9545898A (en) | 1999-05-10 |
US6191130B1 (en) | 2001-02-20 |
ES2177064T3 (es) | 2002-12-01 |
DK1023273T3 (da) | 2002-09-30 |
DE69805831T2 (de) | 2003-01-23 |
EP1023273B1 (de) | 2002-06-05 |
BR9812939A (pt) | 2000-08-08 |
PT1023273E (pt) | 2002-10-31 |
EP1023273A1 (de) | 2000-08-02 |
CN1127490C (zh) | 2003-11-12 |
AU737178B2 (en) | 2001-08-09 |
JP4454848B2 (ja) | 2010-04-21 |
CA2306429C (fr) | 2010-03-30 |
FR2769913B1 (fr) | 2000-03-10 |
JP2001520223A (ja) | 2001-10-30 |
ATE218553T1 (de) | 2002-06-15 |
BR9812939B1 (pt) | 2009-12-01 |
CN1278800A (zh) | 2001-01-03 |
CA2306429A1 (fr) | 1999-04-29 |
WO1999020613A1 (fr) | 1999-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |