DE69802624D1 - Tetrahydroimidazo[2,1-a]isochinolinderivate - Google Patents

Tetrahydroimidazo[2,1-a]isochinolinderivate

Info

Publication number
DE69802624D1
DE69802624D1 DE69802624T DE69802624T DE69802624D1 DE 69802624 D1 DE69802624 D1 DE 69802624D1 DE 69802624 T DE69802624 T DE 69802624T DE 69802624 T DE69802624 T DE 69802624T DE 69802624 D1 DE69802624 D1 DE 69802624D1
Authority
DE
Germany
Prior art keywords
isoquinoline
tetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69802624T
Other languages
English (en)
Other versions
DE69802624T2 (de
Inventor
Dirk Leysen
Gerardus Stephanus Franc Ruigt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69802624D1 publication Critical patent/DE69802624D1/de
Application granted granted Critical
Publication of DE69802624T2 publication Critical patent/DE69802624T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69802624T 1997-06-26 1998-06-23 Tetrahydroimidazo[2,1-a]isochinolinderivate Expired - Fee Related DE69802624T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201950 1997-06-26

Publications (2)

Publication Number Publication Date
DE69802624D1 true DE69802624D1 (de) 2002-01-10
DE69802624T2 DE69802624T2 (de) 2002-08-01

Family

ID=8228485

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802624T Expired - Fee Related DE69802624T2 (de) 1997-06-26 1998-06-23 Tetrahydroimidazo[2,1-a]isochinolinderivate

Country Status (27)

Country Link
US (1) US5994366A (de)
EP (1) EP0887349B1 (de)
JP (1) JP4339939B2 (de)
KR (1) KR100540317B1 (de)
CN (1) CN1139589C (de)
AR (1) AR013132A1 (de)
AT (1) ATE209649T1 (de)
AU (1) AU737924B2 (de)
BR (1) BR9802286A (de)
CA (1) CA2241469C (de)
CZ (1) CZ293265B6 (de)
DE (1) DE69802624T2 (de)
DK (1) DK0887349T3 (de)
ES (1) ES2169471T3 (de)
HK (1) HK1018059A1 (de)
HU (1) HUP9801451A3 (de)
ID (1) ID20494A (de)
IL (1) IL124914A (de)
NO (1) NO311028B1 (de)
NZ (1) NZ330722A (de)
PL (1) PL190281B1 (de)
PT (1) PT887349E (de)
RU (1) RU2204560C2 (de)
SG (1) SG66484A1 (de)
TR (1) TR199801175A1 (de)
TW (1) TW513411B (de)
ZA (1) ZA985559B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20060653A1 (es) * 2004-08-31 2006-09-27 Glaxo Group Ltd Derivados triciclicos condensados como moduladores del receptor 5-ht1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624093A (en) * 1970-03-10 1971-11-30 American Home Prod 5,6-disubstituted-2,3,5,6-tetrahydroimidazo-{8 2,1-{60 {9 isoquinolin-6-ols
US4100165A (en) * 1975-06-17 1978-07-11 Sandoz, Inc. Imidazo [2,1-a]isoquinolines

Also Published As

Publication number Publication date
HUP9801451A2 (hu) 1999-02-01
TR199801175A1 (xx) 1999-01-18
KR19990007323A (ko) 1999-01-25
HK1018059A1 (en) 1999-12-10
SG66484A1 (en) 1999-07-20
CZ204898A3 (cs) 1999-08-11
IL124914A0 (en) 1999-01-26
PT887349E (pt) 2002-04-29
HUP9801451A3 (en) 1999-03-29
EP0887349B1 (de) 2001-11-28
CN1203916A (zh) 1999-01-06
NO982952L (no) 1998-12-28
NO982952D0 (no) 1998-06-25
NO311028B1 (no) 2001-10-01
ES2169471T3 (es) 2002-07-01
JPH1171373A (ja) 1999-03-16
EP0887349A1 (de) 1998-12-30
US5994366A (en) 1999-11-30
RU2204560C2 (ru) 2003-05-20
KR100540317B1 (ko) 2006-04-17
ZA985559B (en) 1999-01-20
TW513411B (en) 2002-12-11
AU737924B2 (en) 2001-09-06
CA2241469C (en) 2008-08-19
PL327053A1 (en) 1999-01-04
NZ330722A (en) 1999-08-30
DE69802624T2 (de) 2002-08-01
DK0887349T3 (da) 2002-03-25
ATE209649T1 (de) 2001-12-15
IL124914A (en) 2000-10-31
HU9801451D0 (en) 1998-08-28
BR9802286A (pt) 2000-02-08
CA2241469A1 (en) 1998-12-26
AU7319698A (en) 1999-01-07
CZ293265B6 (cs) 2004-03-17
PL190281B1 (pl) 2005-11-30
CN1139589C (zh) 2004-02-25
AR013132A1 (es) 2000-12-13
JP4339939B2 (ja) 2009-10-07
ID20494A (id) 1998-12-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL

8339 Ceased/non-payment of the annual fee