DE69731756D1 - Melanomzellinien, welche immundominante melanomantigene teilen und verfahren zu deren anwendung - Google Patents
Melanomzellinien, welche immundominante melanomantigene teilen und verfahren zu deren anwendungInfo
- Publication number
- DE69731756D1 DE69731756D1 DE69731756T DE69731756T DE69731756D1 DE 69731756 D1 DE69731756 D1 DE 69731756D1 DE 69731756 T DE69731756 T DE 69731756T DE 69731756 T DE69731756 T DE 69731756T DE 69731756 D1 DE69731756 D1 DE 69731756D1
- Authority
- DE
- Germany
- Prior art keywords
- melanoma
- cell line
- melanomantic
- immundominant
- melanom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000001441 melanoma Diseases 0.000 title abstract 8
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000007557 Melanoma-Specific Antigens Human genes 0.000 abstract 1
- 108010071463 Melanoma-Specific Antigens Proteins 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2409896P | 1996-08-16 | 1996-08-16 | |
US24098P | 1996-08-16 | ||
PCT/US1997/012868 WO1998006746A2 (en) | 1996-08-16 | 1997-08-04 | Melanoma cell lines expressing shared immunodominant melanoma antigens and methods of using same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69731756D1 true DE69731756D1 (de) | 2004-12-30 |
DE69731756T2 DE69731756T2 (de) | 2005-12-15 |
Family
ID=21818860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69731756T Expired - Lifetime DE69731756T2 (de) | 1996-08-16 | 1997-08-04 | Melanomzellinien, welche immundominante melanomantigene teilen und verfahren zu deren anwendung |
Country Status (8)
Country | Link |
---|---|
US (1) | US6187306B1 (de) |
EP (1) | EP0929318B1 (de) |
JP (5) | JP2001517206A (de) |
AT (1) | ATE283069T1 (de) |
AU (1) | AU3889997A (de) |
CA (1) | CA2263503C (de) |
DE (1) | DE69731756T2 (de) |
WO (1) | WO1998006746A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6096313A (en) * | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
US6277368B1 (en) | 1996-07-25 | 2001-08-21 | The Regents Of The University Of California | Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine |
US5891432A (en) * | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
CA2324138A1 (en) * | 1998-03-20 | 1999-09-23 | Charles A. Nicolette | Novel complementing receptor-ligand pairs and adoptive immunotherapy using same |
GB9810040D0 (en) | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
US6316420B1 (en) * | 1998-07-28 | 2001-11-13 | Technion Research And Development Foundation Ltd. | DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis |
GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
DE19905501B4 (de) | 1999-02-10 | 2005-05-19 | MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie | Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels |
US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
US6541250B2 (en) | 2000-06-22 | 2003-04-01 | Aventis Pasteur Limited | Continuous adherent melanocyte cell line |
ES2341335T3 (es) * | 2002-10-09 | 2010-06-18 | Central Iowa Health System | Vacuna anti-turmor que utiliza celulas tumorales alogenicas que codifica alfa(1,3)-galactosil trnsfersa. |
US20050201993A1 (en) * | 2002-10-09 | 2005-09-15 | Link Charles J.Jr. | Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase |
GB2424273B (en) * | 2002-11-14 | 2007-06-27 | Univ Nottingham | Method for preparing tumour marker protein |
US7709224B2 (en) * | 2003-06-03 | 2010-05-04 | Biosante Pharmaceuticals, Inc. | Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site |
US20050136035A1 (en) * | 2003-06-03 | 2005-06-23 | Derek Ko | Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site |
US20050186178A1 (en) * | 2003-08-28 | 2005-08-25 | Ennist David L. | Oncolytic adenoviral vectors encoding GM-CSF |
PT1889059E (pt) | 2005-05-27 | 2009-10-01 | Oncimmune Ltd | Métodos de imunoensaio melhorados |
GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
US9868961B2 (en) | 2006-03-30 | 2018-01-16 | The Regents Of The University Of California | Methods and compositions for localized secretion of anti-CTLA-4 antibodies |
US7919079B2 (en) | 2006-03-31 | 2011-04-05 | Biosante Pharmaceuticals, Inc. | Cancer immunotherapy compositions and methods of use |
US8574848B2 (en) * | 2006-09-13 | 2013-11-05 | Oncimmune Ltd. | Immunoassay methods |
US7998486B2 (en) | 2006-10-25 | 2011-08-16 | Newlink Genetics Corporation | Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes |
AR060424A1 (es) * | 2007-04-11 | 2008-06-18 | Consejo Nac Invest Cient Tec | Lineas celulares , composiciones para el tratamiento de melanomas que las comprenden procedimientos para preparar las composiciones y metodos de tratamiento |
GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
US9133309B2 (en) * | 2009-10-23 | 2015-09-15 | Dow Corning Toray Co., Ltd. | Organopolysiloxane copolymer |
GB2595063B (en) | 2015-07-31 | 2022-03-09 | Univ Minnesota | Modified cells and methods of therapy |
CN110520530A (zh) | 2016-10-18 | 2019-11-29 | 明尼苏达大学董事会 | 肿瘤浸润性淋巴细胞和治疗方法 |
EP3645021A4 (de) | 2017-06-30 | 2021-04-21 | Intima Bioscience, Inc. | Adeno-assoziierte virale vektoren zur gentherapie |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4595653A (en) | 1981-06-09 | 1986-06-17 | Lee Biomolecular Research Laboratories, Inc. | Process for assaying cellular immunity |
US5045320A (en) | 1989-03-23 | 1991-09-03 | Medical Biology Institute | Large multivalent immunogen |
US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
JPH06501161A (ja) | 1990-09-14 | 1994-02-10 | ザ ジョーンズ ホプキンス ユニバーシティー | 抗腫瘍免疫性の強化と遺伝子治療のための組成物及び方法 |
US5342774A (en) | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
US5637483A (en) * | 1991-10-04 | 1997-06-10 | Whitehead Institute For Biomedical Research | Irradiated tumor cell vaccine engineered to express GM-CSF |
EP1216710B1 (de) * | 1991-10-04 | 2006-04-05 | Whitehead Institute For Biomedical Research | Regulierung der systemischen Immunantworten mittels Zytokinen und Antigenen |
ES2224113T5 (es) * | 1994-02-16 | 2009-05-01 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Polipeptido antigenico asociado al melanoma, epitopos del mismo y vacunas contra melanoma. |
EP0756604A1 (de) * | 1994-04-22 | 1997-02-05 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Melanoma antigene |
US5759535A (en) * | 1994-05-13 | 1998-06-02 | Research Corporation Technologies, Inc. | Immunotherapeutic strategies for the treatment of cancer |
-
1997
- 1997-08-04 EP EP97936164A patent/EP0929318B1/de not_active Expired - Lifetime
- 1997-08-04 JP JP50973298A patent/JP2001517206A/ja not_active Withdrawn
- 1997-08-04 DE DE69731756T patent/DE69731756T2/de not_active Expired - Lifetime
- 1997-08-04 WO PCT/US1997/012868 patent/WO1998006746A2/en active IP Right Grant
- 1997-08-04 AT AT97936164T patent/ATE283069T1/de not_active IP Right Cessation
- 1997-08-04 CA CA2263503A patent/CA2263503C/en not_active Expired - Lifetime
- 1997-08-04 AU AU38899/97A patent/AU3889997A/en not_active Abandoned
- 1997-08-05 US US08/906,029 patent/US6187306B1/en not_active Expired - Lifetime
-
2007
- 2007-10-31 JP JP2007284431A patent/JP2008044969A/ja not_active Withdrawn
-
2011
- 2011-08-01 JP JP2011168822A patent/JP2012001548A/ja not_active Withdrawn
-
2013
- 2013-10-21 JP JP2013218131A patent/JP2014012738A/ja not_active Withdrawn
-
2016
- 2016-03-07 JP JP2016043177A patent/JP2016106137A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE283069T1 (de) | 2004-12-15 |
AU3889997A (en) | 1998-03-06 |
EP0929318B1 (de) | 2004-11-24 |
JP2014012738A (ja) | 2014-01-23 |
WO1998006746A3 (en) | 1998-05-07 |
CA2263503A1 (en) | 1998-02-19 |
EP0929318A2 (de) | 1999-07-21 |
WO1998006746A2 (en) | 1998-02-19 |
JP2001517206A (ja) | 2001-10-02 |
JP2016106137A (ja) | 2016-06-16 |
JP2008044969A (ja) | 2008-02-28 |
CA2263503C (en) | 2012-04-10 |
DE69731756T2 (de) | 2005-12-15 |
US6187306B1 (en) | 2001-02-13 |
JP2012001548A (ja) | 2012-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |