DE69731652T2 - Verfahren zur behandlung von endothelialen verletzungen - Google Patents
Verfahren zur behandlung von endothelialen verletzungen Download PDFInfo
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- DE69731652T2 DE69731652T2 DE69731652T DE69731652T DE69731652T2 DE 69731652 T2 DE69731652 T2 DE 69731652T2 DE 69731652 T DE69731652 T DE 69731652T DE 69731652 T DE69731652 T DE 69731652T DE 69731652 T2 DE69731652 T2 DE 69731652T2
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- endothelial
- epo
- erythropoietin
- chemotherapeutic agent
- cisplatin
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
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- Urology & Nephrology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- External Artificial Organs (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/712,358 US20020052309A1 (en) | 1996-09-11 | 1996-09-11 | Method of treating endothelial injury |
| US712358 | 1996-09-11 | ||
| PCT/US1997/015966 WO1998010650A1 (en) | 1996-09-11 | 1997-09-10 | Method of treating endothelial injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69731652D1 DE69731652D1 (de) | 2004-12-23 |
| DE69731652T2 true DE69731652T2 (de) | 2005-12-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69731652T Expired - Lifetime DE69731652T2 (de) | 1996-09-11 | 1997-09-10 | Verfahren zur behandlung von endothelialen verletzungen |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20020052309A1 (enExample) |
| EP (1) | EP0933995B8 (enExample) |
| JP (3) | JP2001503028A (enExample) |
| CN (2) | CN1113669C (enExample) |
| AT (1) | ATE282425T1 (enExample) |
| CA (1) | CA2265547C (enExample) |
| DE (1) | DE69731652T2 (enExample) |
| DK (1) | DK0933995T3 (enExample) |
| ES (1) | ES2231889T3 (enExample) |
| PT (1) | PT933995E (enExample) |
| WO (1) | WO1998010650A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| IL124015A0 (en) | 1998-04-08 | 1999-01-26 | Yeda Res & Dev | Pharmaceutical compositions comprising a protein |
| FR2786104B1 (fr) * | 1998-11-25 | 2002-12-27 | Centre Nat Rech Scient | Inhibiteurs de l'activation de nf-kb, et leurs utilisations pharmaceutiques |
| US7309687B1 (en) * | 1999-04-13 | 2007-12-18 | The Kenneth S. Warren Institute, Inc. | Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| TR200103785T2 (tr) * | 1999-04-13 | 2002-06-21 | The Kenneth S. Warren Institute, Inc. | Uyarılabilir doku işlevinin periferik olarak uygulanan eritropoietin vasıtasıyla düzenlenmesi |
| US6171620B1 (en) * | 1999-04-27 | 2001-01-09 | Health Research, Inc. | Method of enhancing the efficacy of anti-tumor agents |
| WO2000067776A1 (en) * | 1999-05-11 | 2000-11-16 | Ortho-Mcneil Pharmaceuticals, Inc. | Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration |
| US20030152562A1 (en) * | 2001-10-23 | 2003-08-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Vitro micro-organs, and uses related thereto |
| JP4776843B2 (ja) | 1999-10-01 | 2011-09-21 | イムノゲン インコーポレーティッド | 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法 |
| US6926898B2 (en) | 2000-04-12 | 2005-08-09 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20020061849A1 (en) * | 2000-05-02 | 2002-05-23 | Soren Nielsen | Methods for treatment of diseases associated with inflammation under non-ischemic conditions |
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| US20110076255A1 (en) * | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
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| RU2426174C1 (ru) * | 2010-03-29 | 2011-08-10 | Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" | Способ фармакологической коррекции ишемии конечности, в том числе при l-name индуцированном дефиците оксида азота |
| US9533010B2 (en) * | 2011-10-31 | 2017-01-03 | Amorcyte, Llc | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
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| JPS6045849B2 (ja) * | 1980-08-25 | 1985-10-12 | 林原 健 | ヒトエリトロポエチンの製造方法 |
| US4745099A (en) * | 1985-02-06 | 1988-05-17 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of malignant tumors |
| US5002755A (en) * | 1988-02-18 | 1991-03-26 | Vanderbilt University | Method of controlling nephrotoxicity of anti-tumor plaintum compounds |
| JP2632014B2 (ja) * | 1988-03-03 | 1997-07-16 | 中外製薬株式会社 | 骨髄機能障害性貧血治療剤 |
| US5716644A (en) * | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| JPH0782174A (ja) * | 1993-09-17 | 1995-03-28 | Takeda Chem Ind Ltd | 抗腫瘍剤 |
| US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| JP2001520503A (ja) * | 1994-12-30 | 2001-10-30 | カイロン コーポレイション | インビボにおける固形腫瘍の処置のための方法および組成物 |
| US5635160A (en) * | 1995-06-07 | 1997-06-03 | The University Of North Carolina At Chapel Hill | Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions |
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1996
- 1996-09-11 US US08/712,358 patent/US20020052309A1/en not_active Abandoned
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- 1997-04-15 US US08/842,700 patent/US5922674A/en not_active Expired - Lifetime
- 1997-09-10 CA CA002265547A patent/CA2265547C/en not_active Expired - Fee Related
- 1997-09-10 ES ES97940974T patent/ES2231889T3/es not_active Expired - Lifetime
- 1997-09-10 JP JP10513794A patent/JP2001503028A/ja not_active Withdrawn
- 1997-09-10 DE DE69731652T patent/DE69731652T2/de not_active Expired - Lifetime
- 1997-09-10 PT PT97940974T patent/PT933995E/pt unknown
- 1997-09-10 WO PCT/US1997/015966 patent/WO1998010650A1/en not_active Ceased
- 1997-09-10 EP EP97940974A patent/EP0933995B8/en not_active Revoked
- 1997-09-10 AT AT97940974T patent/ATE282425T1/de active
- 1997-09-10 CN CN97199338A patent/CN1113669C/zh not_active Expired - Fee Related
- 1997-09-10 DK DK97940974T patent/DK0933995T3/da active
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Also Published As
| Publication number | Publication date |
|---|---|
| CN1250281C (zh) | 2006-04-12 |
| JP2001503028A (ja) | 2001-03-06 |
| DE69731652D1 (de) | 2004-12-23 |
| EP0933995A1 (en) | 1999-08-11 |
| EP0933995B1 (en) | 2004-11-17 |
| CN1235512A (zh) | 1999-11-17 |
| CN1429623A (zh) | 2003-07-16 |
| DK0933995T3 (da) | 2005-02-14 |
| HK1022810A1 (en) | 2000-08-25 |
| US7531501B1 (en) | 2009-05-12 |
| ATE282425T1 (de) | 2004-12-15 |
| CN1113669C (zh) | 2003-07-09 |
| CA2265547C (en) | 2009-12-01 |
| US7803408B2 (en) | 2010-09-28 |
| JP2008133305A (ja) | 2008-06-12 |
| JP2009196999A (ja) | 2009-09-03 |
| EP0933995A4 (en) | 2002-08-28 |
| US20090285908A1 (en) | 2009-11-19 |
| WO1998010650A1 (en) | 1998-03-19 |
| CA2265547A1 (en) | 1998-03-19 |
| US20020052309A1 (en) | 2002-05-02 |
| ES2231889T3 (es) | 2005-05-16 |
| US5922674A (en) | 1999-07-13 |
| US20080124401A1 (en) | 2008-05-29 |
| PT933995E (pt) | 2005-02-28 |
| EP0933995B8 (en) | 2005-01-19 |
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