DE69728290D1 - Eine wasserlösliche verbindung und cellulose enhaltende granulate - Google Patents

Eine wasserlösliche verbindung und cellulose enhaltende granulate

Info

Publication number
DE69728290D1
DE69728290D1 DE69728290T DE69728290T DE69728290D1 DE 69728290 D1 DE69728290 D1 DE 69728290D1 DE 69728290 T DE69728290 T DE 69728290T DE 69728290 T DE69728290 T DE 69728290T DE 69728290 D1 DE69728290 D1 DE 69728290D1
Authority
DE
Germany
Prior art keywords
cellulose
water
soluble compound
containing granules
granulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69728290T
Other languages
English (en)
Other versions
DE69728290T2 (de
Inventor
Koutrik Robertus C Van
Gerrit Jan Sijbrands
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Europe BV
Original Assignee
Yamanouchi Europe BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europe BV filed Critical Yamanouchi Europe BV
Publication of DE69728290D1 publication Critical patent/DE69728290D1/de
Application granted granted Critical
Publication of DE69728290T2 publication Critical patent/DE69728290T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Glanulating (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
DE69728290T 1996-08-14 1997-08-14 Eine wasserlösliche verbindung und cellulose enhaltende granulate Expired - Fee Related DE69728290T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96202289 1996-08-14
EP96202289 1996-08-14
PCT/EP1997/004570 WO1998006382A1 (en) 1996-08-14 1997-08-14 Granulates comprising a water soluble compound and cellulose

Publications (2)

Publication Number Publication Date
DE69728290D1 true DE69728290D1 (de) 2004-04-29
DE69728290T2 DE69728290T2 (de) 2004-08-05

Family

ID=8224290

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69728290T Expired - Fee Related DE69728290T2 (de) 1996-08-14 1997-08-14 Eine wasserlösliche verbindung und cellulose enhaltende granulate

Country Status (21)

Country Link
EP (1) EP0948318B1 (de)
JP (1) JP2000516601A (de)
CN (1) CN1139377C (de)
AT (1) ATE262318T1 (de)
AU (1) AU4618097A (de)
BG (1) BG64455B1 (de)
BR (1) BR9711148A (de)
CA (1) CA2264105C (de)
CZ (1) CZ49099A3 (de)
DE (1) DE69728290T2 (de)
DK (1) DK0948318T3 (de)
EA (1) EA002811B1 (de)
ES (1) ES2218702T3 (de)
NO (1) NO990665L (de)
PL (1) PL192959B1 (de)
PT (1) PT948318E (de)
SI (1) SI0948318T1 (de)
SK (1) SK284727B6 (de)
TR (1) TR199900296T2 (de)
WO (1) WO1998006382A1 (de)
ZA (1) ZA977316B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465009B1 (en) * 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
ES2179729B1 (es) * 2000-03-23 2003-12-16 Dreiman Lab Farmaceuticos S A Forma farmaceutica solida de administracion oral dispersable en agua, que comprende rifampicina, isoniazida y piridoxina hidrocloruro, procedimiento para su obtencion y forma de presentacion de dicha forma farmaceutica.
JP4698000B2 (ja) * 2000-06-27 2011-06-08 旭化成ケミカルズ株式会社 水易溶性薬物含有錠剤
JP4547161B2 (ja) * 2004-01-22 2010-09-22 エスエス製薬株式会社 用時溶解型速溶性固形製剤
JP3996626B2 (ja) * 2004-06-22 2007-10-24 塩野義製薬株式会社 口腔内速崩壊錠
EP2042164A4 (de) * 2006-06-23 2010-10-13 Takeda Pharmaceutical Stabilisierte feste zubereitung
JP5198001B2 (ja) * 2006-06-23 2013-05-15 武田薬品工業株式会社 安定化された固形製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049394A (en) * 1987-09-11 1991-09-17 E. R. Squibb & Sons, Inc. Pharmaceutical composition containing high drug load and method for preparing same
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
CA2126441C (en) * 1991-12-30 1999-12-21 David F. Erkoboni Microcrystalline cellulose spheronization composition

Also Published As

Publication number Publication date
BG103175A (en) 1999-08-31
CA2264105A1 (en) 1998-02-19
CN1139377C (zh) 2004-02-25
SI0948318T1 (en) 2004-08-31
PT948318E (pt) 2004-06-30
NO990665L (no) 1999-04-12
BR9711148A (pt) 1999-08-17
WO1998006382A1 (en) 1998-02-19
BG64455B1 (bg) 2005-03-31
NO990665D0 (no) 1999-02-12
EP0948318B1 (de) 2004-03-24
CZ49099A3 (cs) 1999-06-16
JP2000516601A (ja) 2000-12-12
EA199900193A1 (ru) 1999-10-28
SK16799A3 (en) 1999-07-12
ES2218702T3 (es) 2004-11-16
DE69728290T2 (de) 2004-08-05
EA002811B1 (ru) 2002-10-31
EP0948318A1 (de) 1999-10-13
TR199900296T2 (xx) 1999-06-21
ATE262318T1 (de) 2004-04-15
ZA977316B (en) 1999-02-15
PL331588A1 (en) 1999-07-19
DK0948318T3 (da) 2004-06-28
CN1228019A (zh) 1999-09-08
CA2264105C (en) 2007-04-24
SK284727B6 (sk) 2005-10-06
AU4618097A (en) 1998-03-06
PL192959B1 (pl) 2006-12-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTELLAS PHARMA EUROPE B.V., LEIDERDORP, NL

8339 Ceased/non-payment of the annual fee