DE69721257D1 - Neue chirale bisphosphine - Google Patents

Neue chirale bisphosphine

Info

Publication number
DE69721257D1
DE69721257D1 DE69721257T DE69721257T DE69721257D1 DE 69721257 D1 DE69721257 D1 DE 69721257D1 DE 69721257 T DE69721257 T DE 69721257T DE 69721257 T DE69721257 T DE 69721257T DE 69721257 D1 DE69721257 D1 DE 69721257D1
Authority
DE
Germany
Prior art keywords
new chiral
chiral bisphosphine
bisphosphine
new
chiral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69721257T
Other languages
English (en)
Other versions
DE69721257T2 (de
Inventor
Philip Pye
Kai Rossen
P Volante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69721257D1 publication Critical patent/DE69721257D1/de
Publication of DE69721257T2 publication Critical patent/DE69721257T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/5027Polyphosphines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65525Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring
    • C07F9/65527Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655381Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a seven-(or more) membered ring
    • C07F9/65539Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a seven-(or more) membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
DE69721257T 1996-06-12 1997-06-10 Neue chirale bisphosphine Expired - Lifetime DE69721257T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1959096P 1996-06-12 1996-06-12
US19590P 1996-06-12
PCT/US1997/009827 WO1997047632A1 (en) 1996-06-12 1997-06-10 Novel chiral bisphosphines

Publications (2)

Publication Number Publication Date
DE69721257D1 true DE69721257D1 (de) 2003-05-28
DE69721257T2 DE69721257T2 (de) 2004-02-05

Family

ID=21794005

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69721257T Expired - Lifetime DE69721257T2 (de) 1996-06-12 1997-06-10 Neue chirale bisphosphine

Country Status (18)

Country Link
US (2) US5874629A (de)
EP (1) EP0906322B1 (de)
CN (1) CN1082964C (de)
AR (1) AR007555A1 (de)
AT (1) ATE238319T1 (de)
AU (1) AU3303897A (de)
BR (1) BR9709677B1 (de)
CZ (1) CZ295748B6 (de)
DE (1) DE69721257T2 (de)
DK (1) DK0906322T3 (de)
EA (1) EA001377B1 (de)
ES (1) ES2196343T3 (de)
HU (1) HU223052B1 (de)
PT (1) PT906322E (de)
SK (1) SK284369B6 (de)
TW (1) TW450971B (de)
UA (1) UA57742C2 (de)
WO (1) WO1997047632A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334219B1 (en) * 1994-09-26 2001-12-25 Adc Telecommunications Inc. Channel selection for a hybrid fiber coax network
US5977364A (en) * 1998-02-02 1999-11-02 Merck & Co., Inc. Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide
DE10005794A1 (de) * 2000-02-10 2001-08-16 Basf Ag Verbindungen des Phosphors, Arsens und des Antimons
DE60143842D1 (de) * 2000-03-30 2011-02-24 Chirotech Technology Ltd Ruthenium-diphosphin komplexe und ihre verwendung als katalysatoren
US6482952B2 (en) 2000-06-20 2002-11-19 Merck & Co., Inc. Process for preparing acetonides
DE60209344T2 (de) * 2001-01-19 2006-08-03 Chirotech Technology Ltd. Liganden und deren verwendung
GB0313709D0 (en) * 2003-06-13 2003-07-16 Johnson Matthey Plc Ligands
DE602004017456D1 (de) * 2003-06-13 2008-12-11 Johnson Matthey Plc Paracyclophane
US7449601B2 (en) * 2004-12-16 2008-11-11 E. I. Du Pont De Nemours And Company Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids
ES2337826T3 (es) * 2005-03-17 2010-04-29 Basf Se Metodo para la produccion de derivados opticamente activos de acido 3-fenilpropionico y productos de reaccion del mismo.
EP1885688B1 (de) * 2005-05-20 2010-09-22 Dr. Reddy's Laboratories (EU) Limited Asymmetrische hydrierung zur herstellung von diphenylalaninderivaten
GB0700622D0 (en) 2007-01-12 2007-02-21 Johnson Matthey Plc Process for preparing cationic rhodium complexes
GB0716714D0 (en) 2007-08-29 2007-10-10 Johnson Matthey Plc Ligands
GB0812290D0 (en) 2008-07-04 2008-08-13 Johnson Matthey Plc Process for preparing cationic rhodium complexes
GB0915946D0 (en) 2009-09-11 2009-10-28 Univ St Andrews Metal-catalysed carbonylation of unsaturated compounds
CZ303113B6 (cs) * 2010-03-16 2012-04-11 Zentiva, K.S. Zpusob prípravy sitagliptinu
GB201104522D0 (en) 2011-03-17 2011-05-04 Johnson Matthey Plc Complexes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2681057B2 (ja) * 1990-10-01 1997-11-19 高砂香料工業株式会社 2,2’―ビス(ジフェニルホスフィノ)―5,5’,6,6’,7,7’,8,8’―オクタヒドロ―1,1’―ビナフチル及びこれを配位子とする遷移金属錯体
DE4330730A1 (de) * 1993-09-10 1995-03-16 Bayer Ag Neue Bisphosphine für asymmetrische Hydrierkatalysatoren
DE59407903D1 (de) * 1993-10-08 1999-04-15 Hoffmann La Roche Optisch aktive phosphorverbindungen
US5399771A (en) * 1994-06-01 1995-03-21 Merck & Co., Inc. Process of synthesizing binaphthyl derivatives

Also Published As

Publication number Publication date
AR007555A1 (es) 1999-11-10
EA001377B1 (ru) 2001-02-26
SK284369B6 (sk) 2005-02-04
AU3303897A (en) 1998-01-07
HU223052B1 (hu) 2004-03-01
DE69721257T2 (de) 2004-02-05
SK169198A3 (en) 1999-08-06
BR9709677A (pt) 2000-05-09
WO1997047632A1 (en) 1997-12-18
ES2196343T3 (es) 2003-12-16
EA199900016A1 (ru) 1999-06-24
TW450971B (en) 2001-08-21
BR9709677B1 (pt) 2010-05-18
CZ295748B6 (cs) 2005-10-12
CZ409898A3 (cs) 1999-05-12
HUP9902412A2 (hu) 1999-11-29
US5874629A (en) 1999-02-23
UA57742C2 (uk) 2003-07-15
DK0906322T3 (da) 2003-06-02
EP0906322B1 (de) 2003-04-23
ATE238319T1 (de) 2003-05-15
US6043387A (en) 2000-03-28
EP0906322A1 (de) 1999-04-07
PT906322E (pt) 2003-08-29
HUP9902412A3 (en) 2001-09-28
CN1221422A (zh) 1999-06-30
CN1082964C (zh) 2002-04-17

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