DE69718148D1 - Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz - Google Patents
Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatzInfo
- Publication number
- DE69718148D1 DE69718148D1 DE69718148T DE69718148T DE69718148D1 DE 69718148 D1 DE69718148 D1 DE 69718148D1 DE 69718148 T DE69718148 T DE 69718148T DE 69718148 T DE69718148 T DE 69718148T DE 69718148 D1 DE69718148 D1 DE 69718148D1
- Authority
- DE
- Germany
- Prior art keywords
- outlet tube
- enriched fraction
- centrifuge
- enriched
- fraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3698—Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
- Packages (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9600713A SE9600713L (sv) | 1996-02-26 | 1996-02-26 | Metod för separering av celler, speciellt blodplättar och pås-set därför |
PCT/SE1997/000257 WO1997030715A1 (en) | 1996-02-26 | 1997-02-17 | Method for separating cells, especially platelets, and bag assembly therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69718148D1 true DE69718148D1 (de) | 2003-02-06 |
DE69718148T2 DE69718148T2 (de) | 2003-10-02 |
Family
ID=20401543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69718148T Expired - Fee Related DE69718148T2 (de) | 1996-02-26 | 1997-02-17 | Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz |
Country Status (8)
Country | Link |
---|---|
US (2) | US6315706B1 (de) |
EP (1) | EP0885007B1 (de) |
JP (1) | JP4112619B2 (de) |
AT (1) | ATE230271T1 (de) |
AU (1) | AU713297B2 (de) |
DE (1) | DE69718148T2 (de) |
SE (1) | SE9600713L (de) |
WO (1) | WO1997030715A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9600713L (sv) | 1996-02-26 | 1997-10-17 | Omega Medicinteknik Ab | Metod för separering av celler, speciellt blodplättar och pås-set därför |
SE9700495D0 (sv) * | 1997-02-12 | 1997-02-12 | Omega Medicinteknik Ab | Metod och rundpåsesystem samt centrifug för behandling av blod |
DE19846535C2 (de) * | 1998-10-09 | 2000-12-07 | Westfalia Separator Ag | Zentrifuge |
SE516321C2 (sv) | 1999-05-31 | 2001-12-17 | Gambro Inc | Centrifug för behandling av blod och blodkomponenter |
SE517032C2 (sv) | 1999-10-26 | 2002-04-02 | Gambro Inc | Sätt och anordning för behandling av blod och blodkomponenter |
AU2002256086A1 (en) * | 2001-04-09 | 2002-10-21 | Medtronic, Inc. | Methods of isolating blood components using a centrifuge and uses thereof |
EP1476208B1 (de) * | 2002-02-01 | 2011-10-05 | CaridianBCT, Inc. | System zur entnahme und aufbereitung von vollblut |
US7241281B2 (en) * | 2002-04-08 | 2007-07-10 | Thermogenesis Corporation | Blood component separation method and apparatus |
US7211191B2 (en) * | 2004-09-30 | 2007-05-01 | Thermogenesis Corp. | Blood component separation method and apparatus |
CA2642653A1 (en) * | 2002-04-16 | 2003-10-30 | Gambro Bct, Inc. | Blood component processing system, apparatus and method |
EP1627651B1 (de) * | 2002-08-23 | 2012-04-18 | CaridianBCT, Inc. | Verfahren und Gerät zur Trennung von Blutkomponenten |
US7347932B2 (en) * | 2003-08-25 | 2008-03-25 | Gambro Bct, Inc. | Apparatus and method for separating a volume of composite liquid into at least two components |
JP4705098B2 (ja) * | 2004-06-22 | 2011-06-22 | カリディアンビーシーティー、インコーポレーテッド | 複合液体分離のためのバッグアセンブリとその製造方法 |
EP1709983B1 (de) | 2004-12-28 | 2009-12-23 | CaridianBCT, Inc. | Apparat und Methode zur Separation einer Menge Blut in vier Komponenten |
US7442178B2 (en) * | 2005-03-09 | 2008-10-28 | Jacques Chammas | Automated system and method for blood components separation and processing |
US7473216B2 (en) * | 2005-04-21 | 2009-01-06 | Fresenius Hemocare Deutschland Gmbh | Apparatus for separation of a fluid with a separation channel having a mixer component |
CN101222981B (zh) * | 2005-06-22 | 2011-02-02 | 科安比司特公司 | 用于分离分立体积的复合液体的设备和方法 |
US20100210441A1 (en) * | 2005-06-22 | 2010-08-19 | Caridianbct, Inc. | Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid |
WO2007024518A2 (en) * | 2005-08-22 | 2007-03-01 | Gambro Inc. | Apparatus and method for separating a composite liquid into at least two components |
KR20080091109A (ko) * | 2006-01-30 | 2008-10-09 | 감브로 비씨티, 인크. | 전혈 분리 방법에 있어서 pH 조정 |
EP2026908B1 (de) * | 2006-06-07 | 2012-01-11 | CaridianBCT, Inc. | Unwuchtausgleichsanordnung für eine zentrifuge |
JP5259595B2 (ja) * | 2006-09-06 | 2013-08-07 | テルモ ビーシーティー、インコーポレーテッド | 複合液体を少なくとも2つの成分に分離するための装置及び方法 |
WO2008051847A2 (en) * | 2006-10-20 | 2008-05-02 | Caridianbct Biotechnologies, Llc | Methods for washing a red blood cell component and for removing prions therefrom |
US20080147240A1 (en) * | 2006-12-19 | 2008-06-19 | Gambro Bct Inc. | Apparatus for separating a composite liquid with process control on a centrifuge rotor |
WO2008079611A1 (en) * | 2006-12-20 | 2008-07-03 | Caridianbct, Inc. | Apparatus and method for separating a composite liquid into at least two components |
US20080234622A1 (en) * | 2007-03-20 | 2008-09-25 | Gambro Bct Inc. | Methods and Systems for Preparing Blood Products |
US8236184B2 (en) * | 2007-05-14 | 2012-08-07 | Terumo Bct, Inc. | Method for separating a composite liquid into at least two components |
WO2009134521A1 (en) * | 2008-05-02 | 2009-11-05 | Caridianbct, Inc. | Centrifuge apparatus and method for selectively reducing forces on a biologic fluid |
EP2310851B1 (de) * | 2008-07-31 | 2018-11-07 | Terumo BCT, Inc. | Verfahren und vorrichtung zur bestimmung der ausbeute mindestens einer komponente |
EP2451501B1 (de) * | 2009-07-06 | 2013-05-01 | Terumo BCT, Inc. | Verfahren und system zur zur automatischen ladung einer waschlösung in einen blutprozessor mit mehreren einheiten |
DE102010000752A1 (de) * | 2010-01-08 | 2011-07-14 | Andreas Hettich GmbH & Co. KG, 78532 | Kassette und Systemteil, das in Zusammenwirkung mit der Kassette in einer Zentrifuge einsetzbar ist |
US8747289B2 (en) | 2010-03-18 | 2014-06-10 | Syngen Inc. | System for purifying certain cell populations in blood or bone marrow by depleting others |
EP2575925B1 (de) | 2010-05-27 | 2014-10-15 | Terumo BCT, Inc. | Blutprozessor mit mehreren einheiten und temperaturmessung |
EP2576073B1 (de) | 2010-06-07 | 2018-06-13 | Terumo BCT, Inc. | Blutprozessor mit mehreren einheiten und volumenvorhersage |
EP2595755A1 (de) | 2010-07-19 | 2013-05-29 | Terumo BCT, Inc. | Zentrifuge zur verarbeitung von blut und blutbestandteilen |
US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
WO2014160781A1 (en) | 2013-03-26 | 2014-10-02 | Alliance Partners Llc | Biological fluids concentration assembly |
US10004841B2 (en) | 2013-12-09 | 2018-06-26 | Michael C. Larson | Blood purifier device and method |
EP3656215B1 (de) | 2014-06-10 | 2021-08-04 | Biomatrica, INC. | Stabilisierung von thrombozyten bei umgebungstemperatur |
CN108135940B (zh) | 2015-10-14 | 2022-04-15 | 株式会社美加细胞 | 纯化血小板的制造方法 |
US10772916B2 (en) | 2016-09-16 | 2020-09-15 | Fenwal, Inc. | Systems and methods for deriving and collecting platelet products |
IT201900015707A1 (it) * | 2019-09-05 | 2021-03-05 | Emotec Srl | "dispositivo medico ed apparato per la produzione, a circuito chiuso, di plasma ricco di piastrine e derivati, ad uso non trasfusionale" |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3326458A (en) * | 1965-05-28 | 1967-06-20 | Harold T Meryman | Container and process of storing blood |
US3489145A (en) * | 1966-08-08 | 1970-01-13 | Surgeon General Of The Public | Method and apparatus for continuous separation of blood in vivo |
US3519201A (en) * | 1968-05-07 | 1970-07-07 | Us Health Education & Welfare | Seal means for blood separator and the like |
SE332906B (de) * | 1969-08-11 | 1971-02-22 | Aga Ab | |
JPS50107565A (de) * | 1974-01-29 | 1975-08-25 | ||
US4010894A (en) * | 1975-11-21 | 1977-03-08 | International Business Machines Corporation | Centrifuge fluid container |
US4419089A (en) * | 1977-07-19 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Blood cell separator |
US4387848A (en) * | 1977-10-03 | 1983-06-14 | International Business Machines Corporation | Centrifuge assembly |
US4386730A (en) * | 1978-07-21 | 1983-06-07 | International Business Machines Corporation | Centrifuge assembly |
SE412528B (sv) * | 1978-07-25 | 1980-03-10 | Separex Sa | Centrifugrotor och kollaberbar separationsbehallare |
JPS59500340A (ja) | 1982-03-08 | 1984-03-01 | モトロ−ラ・インコ−ポレ−テツド | 集積回路のリ−ドフレ−ム |
US4530691A (en) * | 1983-12-13 | 1985-07-23 | Baxter Travenol Laboratories, Inc. | Centrifuge with movable mandrel |
WO1987006844A1 (en) | 1986-05-16 | 1987-11-19 | Omega Medicinteknik Ab | Method and apparatus for plasmapheresis |
SE459791B (sv) | 1986-05-16 | 1989-08-07 | Omega Medicinteknik Ab | Ringcentrifug |
SE454413B (sv) * | 1986-09-12 | 1988-05-02 | Alfa Laval Separation Ab | Centrifugalseparator med en rotor, vari ett bojligt organ strecker sig ett stycke lengs rotorns omkrets |
SE458342B (sv) * | 1987-07-06 | 1989-03-20 | Alfa Laval Ab | Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar |
SE462015B (sv) | 1987-09-15 | 1990-04-30 | Omega Medicinteknik Ab | Saett och anordning foer tvaettning av blodceller |
DE3815645A1 (de) | 1988-05-07 | 1989-11-16 | Biotest Pharma Gmbh | Verfahren zur herstellung eines reinen thrombozytenkonzentrates aus gesamtblut |
US5116308A (en) * | 1989-01-13 | 1992-05-26 | Terumo Kabushiki Kaisha | Apparatus for processing fluid and method of driving the same |
US5209800A (en) * | 1990-08-20 | 1993-05-11 | Denco, Inc. | Total containment welding of plastic tubes |
SE9302369D0 (sv) * | 1993-07-08 | 1993-07-08 | Omega Medicinteknik Ab | Paassystem avsett foer centrifugalseparationsamt an vaendning av detta paassystem |
US5674173A (en) * | 1995-04-18 | 1997-10-07 | Cobe Laboratories, Inc. | Apparatus for separating particles |
SE9600713L (sv) | 1996-02-26 | 1997-10-17 | Omega Medicinteknik Ab | Metod för separering av celler, speciellt blodplättar och pås-set därför |
SE9700495D0 (sv) * | 1997-02-12 | 1997-02-12 | Omega Medicinteknik Ab | Metod och rundpåsesystem samt centrifug för behandling av blod |
SE9701423D0 (sv) * | 1997-04-16 | 1997-04-16 | Omega Medicinteknik Ab | Behållarset och anordning för blodseparation |
-
1996
- 1996-02-26 SE SE9600713A patent/SE9600713L/xx not_active Application Discontinuation
-
1997
- 1997-02-17 AT AT97906365T patent/ATE230271T1/de not_active IP Right Cessation
- 1997-02-17 AU AU21079/97A patent/AU713297B2/en not_active Ceased
- 1997-02-17 DE DE69718148T patent/DE69718148T2/de not_active Expired - Fee Related
- 1997-02-17 EP EP97906365A patent/EP0885007B1/de not_active Expired - Lifetime
- 1997-02-17 JP JP53005597A patent/JP4112619B2/ja not_active Expired - Fee Related
- 1997-02-17 WO PCT/SE1997/000257 patent/WO1997030715A1/en active IP Right Grant
- 1997-02-17 US US09/125,270 patent/US6315706B1/en not_active Expired - Fee Related
-
2001
- 2001-10-15 US US09/978,428 patent/US6855102B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4112619B2 (ja) | 2008-07-02 |
DE69718148T2 (de) | 2003-10-02 |
WO1997030715A1 (en) | 1997-08-28 |
EP0885007A1 (de) | 1998-12-23 |
JP2001517200A (ja) | 2001-10-02 |
AU713297B2 (en) | 1999-11-25 |
US6855102B2 (en) | 2005-02-15 |
SE9600713L (sv) | 1997-10-17 |
ATE230271T1 (de) | 2003-01-15 |
US6315706B1 (en) | 2001-11-13 |
AU2107997A (en) | 1997-09-10 |
SE9600713D0 (sv) | 1996-02-26 |
US20020016244A1 (en) | 2002-02-07 |
EP0885007B1 (de) | 2003-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: GAMBRO BCT, INC., LAKEWOOD, COL., US |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: CARIDIANBCT, INC., LAKEWOOD, COL., US |
|
8339 | Ceased/non-payment of the annual fee |