DE69718148D1 - Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz - Google Patents

Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Info

Publication number
DE69718148D1
DE69718148D1 DE69718148T DE69718148T DE69718148D1 DE 69718148 D1 DE69718148 D1 DE 69718148D1 DE 69718148 T DE69718148 T DE 69718148T DE 69718148 T DE69718148 T DE 69718148T DE 69718148 D1 DE69718148 D1 DE 69718148D1
Authority
DE
Germany
Prior art keywords
outlet tube
enriched fraction
centrifuge
enriched
fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69718148T
Other languages
English (en)
Other versions
DE69718148T2 (de
Inventor
Peter Unger
Eric Westberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Gambro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Inc filed Critical Gambro Inc
Application granted granted Critical
Publication of DE69718148D1 publication Critical patent/DE69718148D1/de
Publication of DE69718148T2 publication Critical patent/DE69718148T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0644Platelets; Megakaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3698Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0427Platelets; Thrombocytes
DE69718148T 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz Expired - Fee Related DE69718148T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600713A SE9600713L (sv) 1996-02-26 1996-02-26 Metod för separering av celler, speciellt blodplättar och pås-set därför
PCT/SE1997/000257 WO1997030715A1 (en) 1996-02-26 1997-02-17 Method for separating cells, especially platelets, and bag assembly therefor

Publications (2)

Publication Number Publication Date
DE69718148D1 true DE69718148D1 (de) 2003-02-06
DE69718148T2 DE69718148T2 (de) 2003-10-02

Family

ID=20401543

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718148T Expired - Fee Related DE69718148T2 (de) 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Country Status (8)

Country Link
US (2) US6315706B1 (de)
EP (1) EP0885007B1 (de)
JP (1) JP4112619B2 (de)
AT (1) ATE230271T1 (de)
AU (1) AU713297B2 (de)
DE (1) DE69718148T2 (de)
SE (1) SE9600713L (de)
WO (1) WO1997030715A1 (de)

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SE9600713L (sv) 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
SE9700495D0 (sv) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
DE19846535C2 (de) * 1998-10-09 2000-12-07 Westfalia Separator Ag Zentrifuge
SE516321C2 (sv) 1999-05-31 2001-12-17 Gambro Inc Centrifug för behandling av blod och blodkomponenter
SE517032C2 (sv) 1999-10-26 2002-04-02 Gambro Inc Sätt och anordning för behandling av blod och blodkomponenter
EP1381410A2 (de) * 2001-04-09 2004-01-21 Medtronic, Inc. Zentrifugationsverfahren zur isolierung der blutbestandteile, und deren verwendungen
CA2474555A1 (en) * 2002-02-01 2003-08-07 Gambro, Inc. Whole blood collection and processing method
US7241281B2 (en) * 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US7211191B2 (en) * 2004-09-30 2007-05-01 Thermogenesis Corp. Blood component separation method and apparatus
DE60318418T2 (de) * 2002-04-16 2009-01-02 Gambro BCT, Inc., Lakewood System und verfahren zur aufarbeitung von blutbestandteilen
ATE553797T1 (de) * 2002-08-23 2012-05-15 Caridianbct Inc Verfahren und gerät zur trennung von blutkomponenten
US7347932B2 (en) * 2003-08-25 2008-03-25 Gambro Bct, Inc. Apparatus and method for separating a volume of composite liquid into at least two components
US20070209708A1 (en) * 2004-06-22 2007-09-13 Gambro, Inc. Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it
ATE452668T1 (de) 2004-12-28 2010-01-15 Caridianbct Inc Apparat und methode zur separation einer menge blut in vier komponenten
US7442178B2 (en) * 2005-03-09 2008-10-28 Jacques Chammas Automated system and method for blood components separation and processing
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
US20100210441A1 (en) * 2005-06-22 2010-08-19 Caridianbct, Inc. Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid
AU2006262677B2 (en) * 2005-06-22 2010-12-09 Caridianbct, Inc. Apparatus and method for separating discrete volumes of a composite liquid
WO2007024518A2 (en) * 2005-08-22 2007-03-01 Gambro Inc. Apparatus and method for separating a composite liquid into at least two components
US8425448B2 (en) * 2006-01-30 2013-04-23 Terumo Bct, Inc. Adjusting pH in a method of separating whole blood
US7819793B2 (en) * 2006-06-07 2010-10-26 Caridianbct, Inc. Apparatus for separating a composite liquid into at least two components
CN101511406B (zh) * 2006-09-06 2012-08-22 泰尔茂比司特公司 用来将复合液体分离成至少两种成分的设备和方法
US8016736B2 (en) * 2006-10-20 2011-09-13 Caridianbct Biotechnologies, Llc Methods for washing a red blood cell component and for removing prions therefrom
US20080147240A1 (en) * 2006-12-19 2008-06-19 Gambro Bct Inc. Apparatus for separating a composite liquid with process control on a centrifuge rotor
WO2008079611A1 (en) * 2006-12-20 2008-07-03 Caridianbct, Inc. Apparatus and method for separating a composite liquid into at least two components
US20080234622A1 (en) * 2007-03-20 2008-09-25 Gambro Bct Inc. Methods and Systems for Preparing Blood Products
EP2155286B1 (de) * 2007-05-14 2015-07-22 Terumo BCT, Inc. Gerät und verfahren zur auftrennung einer zusammengesetzten flüssigkeit in wenigstens zwei komponenten
US20090272701A1 (en) * 2008-05-02 2009-11-05 Caridianbct, Inc. Centrifuge Apparatus and Method for Selectively Reducing Forces on a Biologic Fluid
US8120760B2 (en) * 2008-07-31 2012-02-21 Caridianbct, Inc. Method and apparatus for separating a composite liquid into at least two components and for determining the yield of at least one component
US20110003675A1 (en) * 2009-07-06 2011-01-06 Caridianbct, Inc. Apparatus and Method for Automatically Loading Washing Solution In A Multi-Unit Blood Processor
DE102010000752A1 (de) * 2010-01-08 2011-07-14 Andreas Hettich GmbH & Co. KG, 78532 Kassette und Systemteil, das in Zusammenwirkung mit der Kassette in einer Zentrifuge einsetzbar ist
US8747289B2 (en) 2010-03-18 2014-06-10 Syngen Inc. System for purifying certain cell populations in blood or bone marrow by depleting others
WO2011149614A1 (en) 2010-05-27 2011-12-01 Caridianbct, Inc. Multi-unit blood processor with temperature sensing
EP2576073B1 (de) 2010-06-07 2018-06-13 Terumo BCT, Inc. Blutprozessor mit mehreren einheiten und volumenvorhersage
WO2012012343A1 (en) 2010-07-19 2012-01-26 Caridianbct, Inc. A centrifuge for processing blood and blood components
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
US9804070B2 (en) 2013-03-26 2017-10-31 Alliance Partners, Llc Biological fluids concentration assembly
US10004841B2 (en) 2013-12-09 2018-06-26 Michael C. Larson Blood purifier device and method
JP6661554B2 (ja) 2014-06-10 2020-03-11 バイオマトリカ,インク. 周囲温度における血小板の安定化
RU2766177C2 (ru) * 2015-10-14 2022-02-08 Мегакарион Корпорейшн Способ получения очищенных тромбоцитов
EP3295973B1 (de) * 2016-09-16 2020-08-26 Fenwal, Inc. Systeme und verfahren zur ableitung und zum sammeln von thrombozytenprodukten
IT201900015707A1 (it) * 2019-09-05 2021-03-05 Emotec Srl "dispositivo medico ed apparato per la produzione, a circuito chiuso, di plasma ricco di piastrine e derivati, ad uso non trasfusionale"

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US3489145A (en) * 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
US3519201A (en) * 1968-05-07 1970-07-07 Us Health Education & Welfare Seal means for blood separator and the like
SE332906B (de) * 1969-08-11 1971-02-22 Aga Ab
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US4010894A (en) * 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
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JPS59500340A (ja) * 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
WO1987006844A1 (en) * 1986-05-16 1987-11-19 Omega Medicinteknik Ab Method and apparatus for plasmapheresis
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SE454413B (sv) * 1986-09-12 1988-05-02 Alfa Laval Separation Ab Centrifugalseparator med en rotor, vari ett bojligt organ strecker sig ett stycke lengs rotorns omkrets
SE458342B (sv) 1987-07-06 1989-03-20 Alfa Laval Ab Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar
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SE9700495D0 (sv) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
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Also Published As

Publication number Publication date
US6315706B1 (en) 2001-11-13
DE69718148T2 (de) 2003-10-02
US6855102B2 (en) 2005-02-15
ATE230271T1 (de) 2003-01-15
SE9600713D0 (sv) 1996-02-26
US20020016244A1 (en) 2002-02-07
AU713297B2 (en) 1999-11-25
SE9600713L (sv) 1997-10-17
EP0885007A1 (de) 1998-12-23
EP0885007B1 (de) 2003-01-02
JP4112619B2 (ja) 2008-07-02
JP2001517200A (ja) 2001-10-02
AU2107997A (en) 1997-09-10
WO1997030715A1 (en) 1997-08-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GAMBRO BCT, INC., LAKEWOOD, COL., US

8327 Change in the person/name/address of the patent owner

Owner name: CARIDIANBCT, INC., LAKEWOOD, COL., US

8339 Ceased/non-payment of the annual fee