DE69716460T2 - Wundheilung und behandlung von fibrose - Google Patents

Wundheilung und behandlung von fibrose

Info

Publication number
DE69716460T2
DE69716460T2 DE69716460T DE69716460T DE69716460T2 DE 69716460 T2 DE69716460 T2 DE 69716460T2 DE 69716460 T DE69716460 T DE 69716460T DE 69716460 T DE69716460 T DE 69716460T DE 69716460 T2 DE69716460 T2 DE 69716460T2
Authority
DE
Germany
Prior art keywords
fibrosis
treatment
wound healing
compound
gelsolin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69716460T
Other languages
English (en)
Other versions
DE69716460D1 (de
Inventor
Mark William James Ferguson
Sharon O'kane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Renovo Ltd
Original Assignee
Renovo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625148.3A external-priority patent/GB9625148D0/en
Application filed by Renovo Ltd filed Critical Renovo Ltd
Application granted granted Critical
Publication of DE69716460D1 publication Critical patent/DE69716460D1/de
Publication of DE69716460T2 publication Critical patent/DE69716460T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
DE69716460T 1996-12-04 1997-12-04 Wundheilung und behandlung von fibrose Expired - Lifetime DE69716460T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9625148.3A GB9625148D0 (en) 1996-12-04 1996-12-04 Wound healing
US3211596P 1996-12-05 1996-12-05
PCT/GB1997/003243 WO1998024465A1 (en) 1996-12-04 1997-12-04 Wound healing and treatment of fibrosis

Publications (2)

Publication Number Publication Date
DE69716460D1 DE69716460D1 (de) 2002-11-21
DE69716460T2 true DE69716460T2 (de) 2003-06-26

Family

ID=26310539

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69716460T Expired - Lifetime DE69716460T2 (de) 1996-12-04 1997-12-04 Wundheilung und behandlung von fibrose

Country Status (12)

Country Link
US (2) US20020103112A1 (de)
EP (1) EP0941108B1 (de)
JP (1) JP2001505219A (de)
AT (1) ATE226084T1 (de)
AU (1) AU744750B2 (de)
CA (1) CA2274002A1 (de)
DE (1) DE69716460T2 (de)
DK (1) DK0941108T3 (de)
ES (1) ES2183220T3 (de)
HK (1) HK1025732A1 (de)
PT (1) PT941108E (de)
WO (1) WO1998024465A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE307586T1 (de) * 1998-08-13 2005-11-15 Hadasit Med Res Service Hemmung von mit gewebetrauma verbundenen pathogenen prozessen
CA2388761A1 (en) * 2001-06-18 2002-12-18 Pfizer Inc. Wound healing biomarkers
US7301020B2 (en) * 2003-06-19 2007-11-27 Wisconsin Alumni Research Foundation Macrolide analogs and methods for identifying same
US9408891B2 (en) * 2003-11-12 2016-08-09 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
AU2004289335A1 (en) * 2003-11-12 2005-05-26 Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
AU2005244865A1 (en) * 2004-05-12 2005-12-01 The Brigham And Women's Hospital, Inc. Use of gelsolin to treat infections
AU2006308431B2 (en) * 2005-10-25 2011-11-10 Adelaide Research & Innovation Pty Ltd Methods and compositions for modulating wound repair
US8574571B2 (en) 2005-10-25 2013-11-05 Womens & Childrens Health Research Institute Methods and compositions for modulating wound repair
JP2009530613A (ja) * 2006-03-15 2009-08-27 ザ・ブリガム・アンド・ウイメンズ・ホスピタル・インコーポレイテッド 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用
ES2895078T3 (es) 2006-03-15 2022-02-17 Brigham & Womens Hospital Inc Uso de gelsolina para diagnosticar y tratar enfermedades inflamatorias
GB0724231D0 (en) * 2007-12-12 2008-01-30 Renono Ltd Methods for inhibiting scarring
CA2749985C (en) 2008-01-25 2020-07-07 The General Hospital Corporation Therapeutic use of gelsolin in chronic renal failure
GB201003652D0 (en) * 2010-03-05 2010-04-21 Univ Cardiff Molecular target for healing or treating wounds
EP3263121B1 (de) * 2010-12-21 2019-02-27 Leidos, Inc. Verfahren und zusammensetzungen zur wundbehandlung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929442A (en) 1986-09-26 1990-05-29 Exovir, Inc. Compositions suitable for human topical application including a growth factor and/or related materials
DE3889479T2 (de) 1987-02-27 1994-12-22 Eastman Kodak Co Mit Nieder-pI-Protein beschichtete Membranstruktur und Verfahren zu ihrer Herstellung und Verwendung.
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
EP0526544B1 (de) 1990-04-11 1998-09-30 Brigham And Women's Hospital Therapeutische verwendung von actin-bindenden verbindungen
AU8647991A (en) 1991-08-26 1993-03-16 State of Oregon Acting by and Through The State of Board of Higher Education on Behalf of The Oregon Health Sciences University, The Keratinocyte-derived conditioned medium as a source of growth factors
GB9206861D0 (en) 1992-03-28 1992-05-13 Univ Manchester Wound healing and treatment of fibrotic disorders
GB2304047A (en) * 1995-08-09 1997-03-12 Univ Manchester Pharmaceutical compositions containing cytokines

Also Published As

Publication number Publication date
ES2183220T3 (es) 2003-03-16
PT941108E (pt) 2003-01-31
HK1025732A1 (en) 2000-11-24
AU744750B2 (en) 2002-02-28
WO1998024465A1 (en) 1998-06-11
US7566446B2 (en) 2009-07-28
US20020103112A1 (en) 2002-08-01
CA2274002A1 (en) 1998-06-11
EP0941108A1 (de) 1999-09-15
US20070087969A1 (en) 2007-04-19
AU5401098A (en) 1998-06-29
DE69716460D1 (de) 2002-11-21
EP0941108B1 (de) 2002-10-16
DK0941108T3 (da) 2002-11-18
ATE226084T1 (de) 2002-11-15
JP2001505219A (ja) 2001-04-17

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Legal Events

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