DE69716242T2 - 3,4-disubstituierte phenylethanolaminotetralin-carboxamid-derivate - Google Patents

3,4-disubstituierte phenylethanolaminotetralin-carboxamid-derivate

Info

Publication number
DE69716242T2
DE69716242T2 DE69716242T DE69716242T DE69716242T2 DE 69716242 T2 DE69716242 T2 DE 69716242T2 DE 69716242 T DE69716242 T DE 69716242T DE 69716242 T DE69716242 T DE 69716242T DE 69716242 T2 DE69716242 T2 DE 69716242T2
Authority
DE
Germany
Prior art keywords
carbon atom
amino
disubstituted
configuration
phenylethanolaminotetraline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69716242T
Other languages
English (en)
Other versions
DE69716242D1 (de
Inventor
Makio Kitazawa
Kosuke-Sanbirezzi-Nish Okazaki
Tetsuro-Shithihaimu-Kash Tamai
Masaru-Kissei Daisanseiy Saito
Nobuyuki Tanaka
Hiroaki Kobayashi
Ken-Kissei Dainiseiyu- Kikuchi
Hideyuki-Kissei Daisa Muranaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13386565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69716242(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69716242D1 publication Critical patent/DE69716242D1/de
Publication of DE69716242T2 publication Critical patent/DE69716242T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Detergent Compositions (AREA)
DE69716242T 1996-02-19 1997-02-18 3,4-disubstituierte phenylethanolaminotetralin-carboxamid-derivate Expired - Lifetime DE69716242T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6888596 1996-02-19
PCT/JP1997/000424 WO1997030023A1 (fr) 1996-02-19 1997-02-18 Derives de phenylethanolaminotetralinecarboxamide 3,4-disubstitue

Publications (2)

Publication Number Publication Date
DE69716242D1 DE69716242D1 (de) 2002-11-14
DE69716242T2 true DE69716242T2 (de) 2003-07-24

Family

ID=13386565

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69716242T Expired - Lifetime DE69716242T2 (de) 1996-02-19 1997-02-18 3,4-disubstituierte phenylethanolaminotetralin-carboxamid-derivate

Country Status (24)

Country Link
US (1) US6133266A (de)
EP (1) EP0882704B1 (de)
JP (1) JP3892045B2 (de)
KR (1) KR100491633B1 (de)
CN (1) CN1100032C (de)
AT (1) ATE225767T1 (de)
AU (1) AU725042B2 (de)
BR (1) BR9707566B1 (de)
CA (1) CA2245490C (de)
CZ (1) CZ293974B6 (de)
DE (1) DE69716242T2 (de)
DK (1) DK0882704T3 (de)
EA (1) EA002143B1 (de)
ES (1) ES2184989T3 (de)
HU (1) HU229400B1 (de)
ID (1) ID16091A (de)
MY (1) MY123853A (de)
NO (1) NO323095B1 (de)
NZ (1) NZ331445A (de)
PL (1) PL186411B1 (de)
PT (1) PT882704E (de)
SG (1) SG72727A1 (de)
TW (1) TW375604B (de)
WO (1) WO1997030023A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009001A1 (fr) * 1997-08-19 1999-02-25 Kissei Pharmaceutical Co., Ltd. Derives de phenylethanolaminotetraline et bronchodilatateurs
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
FR2809725B1 (fr) * 2000-06-06 2004-05-07 Sanofi Synthelabo Propanolaminotetralines, leur preparation et compositions pharmaceutiques en contenant
GB0029562D0 (en) 2000-12-04 2001-01-17 Novartis Ag Organic compounds
KR101028496B1 (ko) * 2003-01-22 2011-04-11 깃세이 야쿠힌 고교 가부시키가이샤 자궁내 태아 발육지연 또는 임신중독증의 예방 또는 치료제
JPWO2006054513A1 (ja) * 2004-11-19 2008-05-29 キッセイ薬品工業株式会社 神経因性疼痛の予防又は治療剤
JPWO2006054514A1 (ja) * 2004-11-19 2008-05-29 キッセイ薬品工業株式会社 神経因性疼痛の予防又は治療用医薬組成物
EP2098511A1 (de) 2008-03-07 2009-09-09 Solvias AG Verfahren zur Herstellung von Verbindungen mit einer Hydronaphtalinstruktur mit einem asymmetrisch substituierten Benzolring
CA2781061A1 (en) * 2009-11-18 2011-05-26 Medicinova, Inc. Treatment of acute exacerbation of asthma and reduction of likelihood of hospitalization of patients suffering therefrom
US20120035265A1 (en) * 2010-03-08 2012-02-09 Medicinova, Inc. Compositions, methods, and devices for the treatment of dysmenorrhea
BR112012025703A2 (pt) * 2010-04-08 2016-07-05 Medicinova Inc métodos e composições para o tratamento de síndrome de intestino irritável

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9107827D0 (en) * 1991-04-12 1991-05-29 Fujisawa Pharmaceutical Co New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
WO1993018007A1 (en) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Novel carbostyril derivative

Also Published As

Publication number Publication date
DK0882704T3 (da) 2003-02-17
PL328530A1 (en) 1999-02-01
BR9707566A (pt) 1999-07-27
AU725042B2 (en) 2000-10-05
EA199800644A1 (ru) 1999-02-25
PL186411B1 (pl) 2004-01-30
HUP9900621A3 (en) 1999-11-29
ID16091A (id) 1997-09-04
ES2184989T3 (es) 2003-04-16
ATE225767T1 (de) 2002-10-15
CA2245490C (en) 2005-10-25
EP0882704A1 (de) 1998-12-09
NO323095B1 (no) 2007-01-02
NZ331445A (en) 2000-01-28
SG72727A1 (en) 2000-05-23
HU229400B1 (en) 2013-12-30
DE69716242D1 (de) 2002-11-14
MY123853A (en) 2006-06-30
TW375604B (en) 1999-12-01
JP3892045B2 (ja) 2007-03-14
KR100491633B1 (ko) 2005-09-09
CN1100032C (zh) 2003-01-29
EA002143B1 (ru) 2001-12-24
EP0882704A4 (de) 2000-06-14
EP0882704B1 (de) 2002-10-09
CZ252398A3 (cs) 1998-12-16
KR19990082638A (ko) 1999-11-25
BR9707566B1 (pt) 2010-08-10
CN1216526A (zh) 1999-05-12
PT882704E (pt) 2003-02-28
HUP9900621A2 (hu) 1999-08-30
AU2001497A (en) 1997-09-02
CA2245490A1 (en) 1997-08-21
CZ293974B6 (cs) 2004-09-15
NO983777L (no) 1998-10-19
US6133266A (en) 2000-10-17
NO983777D0 (no) 1998-08-18
WO1997030023A1 (fr) 1997-08-21

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Legal Events

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