CA2251090A1 - Phenylethanolaminotetralincarboxamide derivatives - Google Patents

Phenylethanolaminotetralincarboxamide derivatives

Info

Publication number
CA2251090A1
CA2251090A1 CA002251090A CA2251090A CA2251090A1 CA 2251090 A1 CA2251090 A1 CA 2251090A1 CA 002251090 A CA002251090 A CA 002251090A CA 2251090 A CA2251090 A CA 2251090A CA 2251090 A1 CA2251090 A1 CA 2251090A1
Authority
CA
Canada
Prior art keywords
carbon atom
amino
configuration
phenylethanolaminotetralincarboxamide
lithagogue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002251090A
Other languages
French (fr)
Other versions
CA2251090C (en
Inventor
Makio Kitazawa
Kosuke Okazaki
Tetsuro Tamai
Masaru Saito
Nobuyuki Tanaka
Hiroaki Kobayashi
Ken Kikuchi
Hideyuki Muranaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co., Ltd.
Makio Kitazawa
Kosuke Okazaki
Tetsuro Tamai
Masaru Saito
Nobuyuki Tanaka
Hiroaki Kobayashi
Ken Kikuchi
Hideyuki Muranaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co., Ltd., Makio Kitazawa, Kosuke Okazaki, Tetsuro Tamai, Masaru Saito, Nobuyuki Tanaka, Hiroaki Kobayashi, Ken Kikuchi, Hideyuki Muranaka filed Critical Kissei Pharmaceutical Co., Ltd.
Priority claimed from PCT/JP1997/001159 external-priority patent/WO1997038970A1/en
Publication of CA2251090A1 publication Critical patent/CA2251090A1/en
Application granted granted Critical
Publication of CA2251090C publication Critical patent/CA2251090C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Phenylethanolaminotetralincarboxamide derivative represented by general formula (I) and pharmacologically acceptable salts thereof, wherein A represents lower alkylene; B represents amino, di(lower alkyl)amino or 3- to 7-membered alicyclic amino which may bear oxygen on the ring; the asterisked carbon atom represents a carbon atom with an R- or S-configuration or a mixture of such atoms; and the carbon atom labeled with (S) represents a carbon atom with an S-configuration. These compounds have selective .beta.2-adrenergic receptor stimulating effects while reducing the burden on the heart, such as tachycardia, and are useful as preventives for threatened abortion and premature birth, bronchodilator, and agents for remission and lithagogue for urinary calculus.
CA002251090A 1996-04-12 1997-04-04 Phenylethanolaminotetralincarboxamide derivatives Expired - Fee Related CA2251090C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12622596 1996-04-12
JP8/126225 1996-04-12
PCT/JP1997/001159 WO1997038970A1 (en) 1996-04-12 1997-04-04 Phenylethanolaminotetralincarboxamide derivatives

Publications (2)

Publication Number Publication Date
CA2251090A1 true CA2251090A1 (en) 1997-10-23
CA2251090C CA2251090C (en) 2006-02-21

Family

ID=35985384

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002251090A Expired - Fee Related CA2251090C (en) 1996-04-12 1997-04-04 Phenylethanolaminotetralincarboxamide derivatives

Country Status (1)

Country Link
CA (1) CA2251090C (en)

Also Published As

Publication number Publication date
CA2251090C (en) 2006-02-21

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Legal Events

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EEER Examination request
MKLA Lapsed