DE69700719T2 - Diosmetin-Säuren und Ester und diese enthaltende pharmazeutische Zusammensetzungen - Google Patents

Diosmetin-Säuren und Ester und diese enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE69700719T2
DE69700719T2 DE69700719T DE69700719T DE69700719T2 DE 69700719 T2 DE69700719 T2 DE 69700719T2 DE 69700719 T DE69700719 T DE 69700719T DE 69700719 T DE69700719 T DE 69700719T DE 69700719 T2 DE69700719 T2 DE 69700719T2
Authority
DE
Germany
Prior art keywords
ch2ch
esters
acids
diosmetic
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69700719T
Other languages
English (en)
Other versions
DE69700719D1 (de
Inventor
Michel Wierzbicki
Marie-Francoise Boussard
Tony Verbeuren
Marie-Odile Vallez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69700719D1 publication Critical patent/DE69700719D1/de
Application granted granted Critical
Publication of DE69700719T2 publication Critical patent/DE69700719T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
DE69700719T 1996-04-25 1997-04-23 Diosmetin-Säuren und Ester und diese enthaltende pharmazeutische Zusammensetzungen Expired - Lifetime DE69700719T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9605247A FR2748025B1 (fr) 1996-04-25 1996-04-25 Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
DE69700719D1 DE69700719D1 (de) 1999-12-09
DE69700719T2 true DE69700719T2 (de) 2000-06-08

Family

ID=9491593

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69700719T Expired - Lifetime DE69700719T2 (de) 1996-04-25 1997-04-23 Diosmetin-Säuren und Ester und diese enthaltende pharmazeutische Zusammensetzungen

Country Status (17)

Country Link
US (1) US5792789A (de)
EP (1) EP0803503B1 (de)
JP (1) JP4144917B2 (de)
CN (1) CN1098848C (de)
AT (1) ATE186299T1 (de)
AU (1) AU707156B2 (de)
CA (1) CA2203463C (de)
DE (1) DE69700719T2 (de)
DK (1) DK0803503T3 (de)
ES (1) ES2143833T3 (de)
FR (1) FR2748025B1 (de)
GR (1) GR3031752T3 (de)
HU (1) HU223349B1 (de)
NO (1) NO315468B1 (de)
NZ (1) NZ314678A (de)
PL (1) PL187257B1 (de)
ZA (1) ZA973646B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821361A (en) 1996-06-11 1998-10-13 Protein Technologies International, Inc. Recovery of isoflavones from soy molasses
FR2753969B1 (fr) * 1996-09-27 1998-10-30 Adir Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6083553A (en) * 1998-06-05 2000-07-04 Protein Technologies International, Inc. Recovery of isoflavones from soy molasses
US7638554B2 (en) * 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US20030229136A1 (en) * 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
FR2882654B1 (fr) * 2005-03-01 2007-04-27 Servier Lab Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques
FR2929276B1 (fr) * 2008-04-01 2010-04-23 Servier Lab Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US9209585B2 (en) * 2010-02-18 2015-12-08 Tyco Electronics Corporation Crimping tool head
CZ2012242A3 (cs) 2012-04-10 2013-09-04 Univerzita Palackého Pouzití komplexu medi obsahujících 2-fenyl-3-hydroxychinolin-4(1H)-on a deriváty 1,10-fenanthrolinu pro prípravu léciv pro lécbu nádorových onemocnení
FR2999934B1 (fr) * 2012-12-21 2015-02-20 Servier Lab Composition pharmaceutique sous la forme d'une suspension orale comprenant une fraction flavonoique et de la gomme xanthane
CN106031723A (zh) * 2015-09-29 2016-10-19 西南大学 香叶木素的抗炎活性及其制剂应用
CN109280067B (zh) * 2017-07-21 2022-07-05 南京正大天晴制药有限公司 香叶木苷衍生物、其制备方法以及医药用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2350804A (en) * 1939-07-22 1944-06-06 Ohta Masaki Derivatives of hesperidin and process for preparing the same
US2897211A (en) * 1955-11-02 1959-07-28 Recordati Lab Farmacologico S Hydroxychromone derivatives and method of preparing the same
FR1273871A (fr) * 1958-05-05 1961-10-20 Recordati Lab Farmacologico S Procédé pour la préparation du flavone-7-oxyacétate d'éthyle
BE606547A (fr) * 1960-08-04 1961-11-16 Ind Chimique Sa Nouveaux dérivés flavoniques et leur procédé de préparation
CH477435A (fr) * 1960-08-04 1969-08-31 Blaise Rolland Procédé de préparation de nouveaux dérivés flavoniques
FR2081569A1 (en) * 1970-03-10 1971-12-10 Savel Jean Diethyl flavone-5,7-dioxyacetate vitamin p - combines coronary, vaso-dilator, lipid - and urea-metabolic activities
FR2088127B1 (de) * 1970-05-21 1973-04-06 Biosedra Lab
FR2281112A1 (fr) * 1974-08-05 1976-03-05 Lipha Nouveau medicament choleretique et anti-inflammatoire
FR2623808B1 (fr) * 1987-12-01 1990-03-09 Adir Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2726273B1 (fr) * 1994-10-26 1996-12-06 Adir Nouveaux derives de la diosmetine, leur procede de preparation et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
AU707156B2 (en) 1999-07-01
EP0803503A1 (de) 1997-10-29
CN1098848C (zh) 2003-01-15
US5792789A (en) 1998-08-11
FR2748025B1 (fr) 1998-10-30
HU9700810D0 (en) 1997-06-30
FR2748025A1 (fr) 1997-10-31
NO315468B1 (no) 2003-09-08
NO971861D0 (no) 1997-04-23
AU1902797A (en) 1997-10-30
CA2203463C (fr) 2002-08-20
HU223349B1 (hu) 2004-06-28
JP4144917B2 (ja) 2008-09-03
PL319652A1 (en) 1997-10-27
EP0803503B1 (de) 1999-11-03
ATE186299T1 (de) 1999-11-15
JPH1036365A (ja) 1998-02-10
CA2203463A1 (fr) 1997-10-25
NZ314678A (en) 1998-12-23
PL187257B1 (pl) 2004-06-30
ZA973646B (en) 1997-11-19
CN1167763A (zh) 1997-12-17
ES2143833T3 (es) 2000-05-16
GR3031752T3 (en) 2000-02-29
HUP9700810A2 (hu) 1999-09-28
DK0803503T3 (da) 2000-04-10
HUP9700810A3 (en) 2000-06-28
DE69700719D1 (de) 1999-12-09
NO971861L (no) 1997-10-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR