DE69632034D1 - Pharmazeutische zubereitung zur topischen applikation enthaltend acyclovir und hydrokortison - Google Patents

Pharmazeutische zubereitung zur topischen applikation enthaltend acyclovir und hydrokortison

Info

Publication number
DE69632034D1
DE69632034D1 DE69632034T DE69632034T DE69632034D1 DE 69632034 D1 DE69632034 D1 DE 69632034D1 DE 69632034 T DE69632034 T DE 69632034T DE 69632034 T DE69632034 T DE 69632034T DE 69632034 D1 DE69632034 D1 DE 69632034D1
Authority
DE
Germany
Prior art keywords
hydrocortison
pharmaceutical preparation
topical application
application containing
containing acyclovir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69632034T
Other languages
English (en)
Other versions
DE69632034T2 (de
Inventor
Johan Georg Harmenberg
Ann Harriet Marg Kristofferson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medivir AB
Original Assignee
Medivir AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir AB filed Critical Medivir AB
Publication of DE69632034D1 publication Critical patent/DE69632034D1/de
Application granted granted Critical
Publication of DE69632034T2 publication Critical patent/DE69632034T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DE69632034T 1995-02-06 1996-02-02 Pharmazeutische zubereitung zur topischen applikation enthaltend acyclovir und hydrokortison Expired - Lifetime DE69632034T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOPCT/SE95/00114 1995-02-06
SE9500114 1995-02-06
PCT/SE1996/000124 WO1996024355A1 (en) 1995-02-06 1996-02-02 Novel pharmaceutical combination

Publications (2)

Publication Number Publication Date
DE69632034D1 true DE69632034D1 (de) 2004-05-06
DE69632034T2 DE69632034T2 (de) 2004-10-14

Family

ID=20396821

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69632034T Expired - Lifetime DE69632034T2 (de) 1995-02-06 1996-02-02 Pharmazeutische zubereitung zur topischen applikation enthaltend acyclovir und hydrokortison
DE122010000032C Pending DE122010000032I1 (de) 1995-02-06 1996-02-02 Ion enthaltend acyclovir und hydrokortison
DE69637828T Expired - Fee Related DE69637828D1 (de) 1995-02-06 1996-02-02 Pharmazeutische Formulierung zur topischen Anwendung enthaltend eine antivirale Substanz und ein Glucocorticoid

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE122010000032C Pending DE122010000032I1 (de) 1995-02-06 1996-02-02 Ion enthaltend acyclovir und hydrokortison
DE69637828T Expired - Fee Related DE69637828D1 (de) 1995-02-06 1996-02-02 Pharmazeutische Formulierung zur topischen Anwendung enthaltend eine antivirale Substanz und ein Glucocorticoid

Country Status (30)

Country Link
US (2) USRE39264E1 (de)
EP (2) EP0809498B1 (de)
JP (2) JP4260220B2 (de)
KR (1) KR100431042B1 (de)
CN (1) CN1131034C (de)
AR (1) AR002030A1 (de)
AT (2) ATE421358T1 (de)
AU (1) AU716809B2 (de)
CA (1) CA2211389C (de)
DE (3) DE69632034T2 (de)
DK (1) DK0809498T3 (de)
DZ (1) DZ1966A1 (de)
ES (1) ES2214528T3 (de)
FI (1) FI119415B (de)
FR (1) FR10C0038I2 (de)
HK (1) HK1004368A1 (de)
HR (1) HRP960034B1 (de)
IL (1) IL116913A0 (de)
MA (1) MA23800A1 (de)
MY (1) MY119365A (de)
NO (1) NO314220B1 (de)
NZ (1) NZ301407A (de)
PT (1) PT809498E (de)
SA (1) SA96160590B1 (de)
SI (1) SI0809498T1 (de)
TN (1) TNSN96024A1 (de)
TW (1) TW438585B (de)
WO (1) WO1996024355A1 (de)
YU (1) YU49477B (de)
ZA (1) ZA96527B (de)

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SE9803929D0 (sv) * 1998-11-18 1998-11-18 Medivir Ab Antiviral formulation
US7223387B2 (en) 1998-11-18 2007-05-29 Medivir Ab Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester
US7655252B2 (en) 1999-04-28 2010-02-02 The Regents Of The University Of Michigan Antimicrobial nanoemulsion compositions and methods
US7767216B2 (en) * 1999-04-28 2010-08-03 The Regents Of The University Of Michigan Antimicrobial compositions and methods of use
FR2837102B1 (fr) * 2002-03-18 2004-10-08 Palbian Snc Composition a l'etat de gel aqueux, procede de fabrication et utilisation pour la fabrication d'un medicament, notamment antiherpetique
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
US20050208083A1 (en) 2003-06-04 2005-09-22 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
AR045536A1 (es) * 2003-08-29 2005-11-02 Ranbaxy Lab Ltd Inhibidores de la fosfodiesterasa tipo -iv
EP1694655A2 (de) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Phosphodiesteraseinhibitoren
US7618950B2 (en) * 2004-07-07 2009-11-17 Arigen Pharmaceuticals, Inc. Method for treatment and prevention of herpes zoster by topical application
CL2006000697A1 (es) * 2005-03-30 2008-05-09 Novartis Ag Uso de famciclovir para el tratamiento del herpes labial recurrente.
EP1871349A1 (de) * 2005-04-11 2008-01-02 Nanobio Corporation Quartäre ammoniumhalogenide zur behandlung von infektionskrankheiten
CA2618974C (en) * 2005-08-09 2014-01-28 Nanobio Corporation Nanoemulsion compositions having anti-inflammatory activity
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
US7797337B2 (en) * 2005-09-29 2010-09-14 Scenera Technologies, Llc Methods, systems, and computer program products for automatically associating data with a resource as metadata based on a characteristic of the resource
US20090221664A1 (en) 2005-10-19 2009-09-03 Abhijit Ray Pharmaceutical compositions of muscarinic receptor antagonists
EP1948167A1 (de) * 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Zusammensetzungen von phosphodiesterase-typ-iv-hemmern
FR2900577B1 (fr) * 2006-05-04 2008-09-12 Goemar Lab Sa Nouveaux medicaments pour les traitements contre le virus de l'herpes
CA2664247A1 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
MX2009009793A (es) * 2007-03-14 2009-10-16 Ranbaxy Lab Ltd Derivados de pirazolo (3,4-b) piridina como inhibidores de fosfodiesterasa.
WO2008134033A1 (en) * 2007-04-26 2008-11-06 The Trustees Of The University Of Pennsylvania Dna polymerase inhibitors composition and methods
US8747872B2 (en) 2007-05-02 2014-06-10 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
JP4972062B2 (ja) * 2008-03-17 2012-07-11 メディヴィル・アクチエボラーグ 抗ウイルス製剤
EP2111861A1 (de) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Zusammensetzungen von Phosphodiesterase-IV-Hemmern
US20090291895A1 (en) * 2008-05-23 2009-11-26 Wong Scott W Methods and Compositions for the Treatment of Inflammatory Diseases
WO2011035120A2 (en) * 2009-09-17 2011-03-24 Gk Ventures, L.L.C. Therapeutic composition to treat lesions caused by herpes simplex virus
CN102049050B (zh) * 2009-11-02 2014-06-18 重庆华邦制药有限公司 抗疱疹病毒感染的药物组合物
EP2489354A1 (de) 2011-02-18 2012-08-22 Vironova AB Pharmazeutische Formulierung enthaltend B220 zur topischen Behandlung von Herpes
ITMI20111747A1 (it) * 2011-09-28 2013-03-29 Fidia Farmaceutici Composizioni farmaceutiche topiche comprendenti aciclovir
FR2983731B1 (fr) * 2011-12-07 2014-04-25 Univ Paris Descartes Emulsions topiques a base de melanges eutectiques d'anesthesiques locaux et d'acide gras
US10682370B2 (en) * 2013-03-13 2020-06-16 Nal Pharmaceutical Group Limited Topical antiviral composition containing a local anesthetic and method of making the same
CN104324039A (zh) * 2014-10-20 2015-02-04 付茜 一种治疗人身体表面脂肪瘤的药剂及使用方法
CN108853140A (zh) * 2018-07-18 2018-11-23 豆立忠 一种多药物模块软膏及其制备方法
ES2955089T3 (es) * 2018-08-17 2023-11-28 Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi Composición tópica estable en fase que comprende aciclovir e hidrocortisona
AU2020292356A1 (en) 2019-06-14 2022-01-20 Propella Therapeutics, Inc. Topical acyclovir formulations and uses thereof
CN112569243A (zh) * 2019-09-30 2021-03-30 神农医药科技有限公司 制备治疗阿尔茨海默病的药物
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US4512978A (en) 1980-01-24 1985-04-23 Inwood Louis R Dermatological composition useful in the treatment of psoriasis
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GB9601544D0 (en) 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals

Also Published As

Publication number Publication date
ZA96527B (en) 1996-08-06
CN1131034C (zh) 2003-12-17
DE69637828D1 (de) 2009-03-12
DZ1966A1 (fr) 2002-10-15
FR10C0038I1 (de) 2010-10-15
ATE421358T1 (de) 2009-02-15
NO314220B1 (no) 2003-02-17
MA23800A1 (fr) 1996-10-01
PT809498E (pt) 2004-06-30
NO973612D0 (no) 1997-08-05
WO1996024355A1 (en) 1996-08-15
EP1419803A2 (de) 2004-05-19
MY119365A (en) 2005-05-31
KR100431042B1 (ko) 2004-06-16
EP0809498A1 (de) 1997-12-03
HK1004368A1 (en) 1998-11-27
CA2211389C (en) 2007-11-20
CA2211389A1 (en) 1996-08-15
SI0809498T1 (en) 2004-12-31
FI119415B (fi) 2008-11-14
EP0809498B1 (de) 2004-03-31
USRE39264E1 (en) 2006-09-05
YU7296A (sh) 1998-08-14
DK0809498T3 (da) 2004-05-10
TNSN96024A1 (fr) 2005-03-15
NO973612L (no) 1997-09-26
JP2007284452A (ja) 2007-11-01
NZ301407A (en) 1999-01-28
EP1419803A3 (de) 2004-06-09
HRP960034A2 (en) 1997-10-31
KR19980701959A (ko) 1998-06-25
DE69632034T2 (de) 2004-10-14
FR10C0038I2 (de) 2011-04-29
AU4682196A (en) 1996-08-27
FI973243A (fi) 1997-08-06
JPH11506417A (ja) 1999-06-08
TW438585B (en) 2001-06-07
YU49477B (sh) 2006-05-25
EP1419803B1 (de) 2009-01-21
FI973243A0 (fi) 1997-08-06
AR002030A1 (es) 1998-01-07
CN1179718A (zh) 1998-04-22
AU716809B2 (en) 2000-03-09
JP4260220B2 (ja) 2009-04-30
IL116913A0 (en) 1996-05-14
ES2214528T3 (es) 2004-09-16
US6337324B1 (en) 2002-01-08
ATE262907T1 (de) 2004-04-15
SA96160590B1 (ar) 2005-10-05
DE122010000032I1 (de) 2010-10-21
HRP960034B1 (en) 2002-02-28

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