NO314220B1 - Farmasöytisk preparat for dermal eller mukosal administrasjon, og anvendelse derav - Google Patents
Farmasöytisk preparat for dermal eller mukosal administrasjon, og anvendelse derav Download PDFInfo
- Publication number
- NO314220B1 NO314220B1 NO19973612A NO973612A NO314220B1 NO 314220 B1 NO314220 B1 NO 314220B1 NO 19973612 A NO19973612 A NO 19973612A NO 973612 A NO973612 A NO 973612A NO 314220 B1 NO314220 B1 NO 314220B1
- Authority
- NO
- Norway
- Prior art keywords
- combination
- pharmaceutical preparation
- hydrocortisone
- cream
- foscarnet
- Prior art date
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- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 24
- 230000002500 effect on skin Effects 0.000 title claims description 8
- ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical compound OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 claims description 139
- 239000006071 cream Substances 0.000 claims description 73
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims description 62
- 229960000890 hydrocortisone Drugs 0.000 claims description 31
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 claims description 29
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- XUYJLQHKOGNDPB-UHFFFAOYSA-N phosphonoacetic acid Chemical compound OC(=O)CP(O)(O)=O XUYJLQHKOGNDPB-UHFFFAOYSA-N 0.000 claims description 10
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- GWFOVSGRNGAGDL-FSDSQADBSA-N 2-amino-9-[(1r,2r,3s)-2,3-bis(hydroxymethyl)cyclobutyl]-3h-purin-6-one Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1C[C@H](CO)[C@H]1CO GWFOVSGRNGAGDL-FSDSQADBSA-N 0.000 claims description 5
- JNTOCHDNEULJHD-UHFFFAOYSA-N Penciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(CCC(CO)CO)C=N2 JNTOCHDNEULJHD-UHFFFAOYSA-N 0.000 claims description 5
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- SUPKOOSCJHTBAH-UHFFFAOYSA-N adefovir Chemical compound NC1=NC=NC2=C1N=CN2CCOCP(O)(O)=O SUPKOOSCJHTBAH-UHFFFAOYSA-N 0.000 claims description 5
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- SCBFBAWJWLXVHS-UHFFFAOYSA-N 2-amino-9-[4-hydroxy-2-(hydroxymethyl)butyl]-3h-purin-6-one Chemical compound N1C(N)=NC(=O)C2=C1N(CC(CO)CCO)C=N2 SCBFBAWJWLXVHS-UHFFFAOYSA-N 0.000 claims description 4
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- MDCGTBRYRLWFJI-WDCKKOMHSA-N 2-amino-9-(2-hydroxyethoxymethyl)-3h-purin-6-one;(8s,9s,10r,11s,13s,14s,17r)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-one Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2.O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MDCGTBRYRLWFJI-WDCKKOMHSA-N 0.000 claims description 3
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- WXURHACBFYSXBI-GQKYHHCASA-N flumethasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]2(C)C[C@@H]1O WXURHACBFYSXBI-GQKYHHCASA-N 0.000 claims description 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
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- A61K31/66—Phosphorus compounds
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
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- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9500114 | 1995-02-06 | ||
PCT/SE1996/000124 WO1996024355A1 (en) | 1995-02-06 | 1996-02-02 | Novel pharmaceutical combination |
Publications (3)
Publication Number | Publication Date |
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NO973612D0 NO973612D0 (no) | 1997-08-05 |
NO973612L NO973612L (no) | 1997-09-26 |
NO314220B1 true NO314220B1 (no) | 2003-02-17 |
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Application Number | Title | Priority Date | Filing Date |
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NO19973612A NO314220B1 (no) | 1995-02-06 | 1997-08-05 | Farmasöytisk preparat for dermal eller mukosal administrasjon, og anvendelse derav |
Country Status (30)
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US (2) | US6337324B1 (de) |
EP (2) | EP1419803B1 (de) |
JP (2) | JP4260220B2 (de) |
KR (1) | KR100431042B1 (de) |
CN (1) | CN1131034C (de) |
AR (1) | AR002030A1 (de) |
AT (2) | ATE421358T1 (de) |
AU (1) | AU716809B2 (de) |
CA (1) | CA2211389C (de) |
DE (3) | DE122010000032I1 (de) |
DK (1) | DK0809498T3 (de) |
DZ (1) | DZ1966A1 (de) |
ES (1) | ES2214528T3 (de) |
FI (1) | FI119415B (de) |
FR (1) | FR10C0038I2 (de) |
HK (1) | HK1004368A1 (de) |
HR (1) | HRP960034B1 (de) |
IL (1) | IL116913A0 (de) |
MA (1) | MA23800A1 (de) |
MY (1) | MY119365A (de) |
NO (1) | NO314220B1 (de) |
NZ (1) | NZ301407A (de) |
PT (1) | PT809498E (de) |
SA (1) | SA96160590B1 (de) |
SI (1) | SI0809498T1 (de) |
TN (1) | TNSN96024A1 (de) |
TW (1) | TW438585B (de) |
WO (1) | WO1996024355A1 (de) |
YU (1) | YU49477B (de) |
ZA (1) | ZA96527B (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
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GB9601544D0 (en) * | 1996-01-26 | 1996-03-27 | Smithkline Beecham Plc | Pharmaceuticals |
IT1287114B1 (it) * | 1996-10-31 | 1998-08-04 | Recordati Chem Pharm | Composizioni farmaceutiche antierpetiche per applicatori topici, contenenti aciclovir |
US7223387B2 (en) | 1998-11-18 | 2007-05-29 | Medivir Ab | Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester |
SE9803929D0 (sv) * | 1998-11-18 | 1998-11-18 | Medivir Ab | Antiviral formulation |
US7655252B2 (en) | 1999-04-28 | 2010-02-02 | The Regents Of The University Of Michigan | Antimicrobial nanoemulsion compositions and methods |
US7767216B2 (en) * | 1999-04-28 | 2010-08-03 | The Regents Of The University Of Michigan | Antimicrobial compositions and methods of use |
FR2837102B1 (fr) * | 2002-03-18 | 2004-10-08 | Palbian Snc | Composition a l'etat de gel aqueux, procede de fabrication et utilisation pour la fabrication d'un medicament, notamment antiherpetique |
US20040023935A1 (en) * | 2002-08-02 | 2004-02-05 | Dey, L.P. | Inhalation compositions, methods of use thereof, and process for preparation of same |
US20040109826A1 (en) * | 2002-12-06 | 2004-06-10 | Dey, L.P. | Stabilized albuterol compositions and method of preparation thereof |
US20050208083A1 (en) * | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
NZ545748A (en) * | 2003-08-29 | 2010-03-26 | Ranbaxy Lab Ltd | Isoxazoline derivatives as inhibitors of phosphodiesterase type-IV |
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