DE69631169D1 - Herstellung von (s)-decahydroisochinolin-3-carbonsäure-t-butylamid - Google Patents

Herstellung von (s)-decahydroisochinolin-3-carbonsäure-t-butylamid

Info

Publication number
DE69631169D1
DE69631169D1 DE69631169T DE69631169T DE69631169D1 DE 69631169 D1 DE69631169 D1 DE 69631169D1 DE 69631169 T DE69631169 T DE 69631169T DE 69631169 T DE69631169 T DE 69631169T DE 69631169 D1 DE69631169 D1 DE 69631169D1
Authority
DE
Germany
Prior art keywords
tic
butylamide
decahydroisochinolin
preparation
carbonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69631169T
Other languages
English (en)
Other versions
DE69631169T2 (de
Inventor
R Allen
Scott Jenkins
Loraine Klein
Robert Erickson
Diana Froen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PCBU Services Inc
Original Assignee
PCBU Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PCBU Services Inc filed Critical PCBU Services Inc
Publication of DE69631169D1 publication Critical patent/DE69631169D1/de
Application granted granted Critical
Publication of DE69631169T2 publication Critical patent/DE69631169T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69631169T 1996-02-20 1996-10-18 Herstellung von (s)-decahydroisochinolin-3-carbonsäure-t-butylamid Expired - Fee Related DE69631169T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US603744 1996-02-20
US08/603,744 US5587481A (en) 1996-02-20 1996-02-20 Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
PCT/US1996/016628 WO1997030976A1 (en) 1996-02-20 1996-10-18 Preparation of (s)-decahydroisoquinoline-3-carboxylic acid t-butylamide

Publications (2)

Publication Number Publication Date
DE69631169D1 true DE69631169D1 (de) 2004-01-29
DE69631169T2 DE69631169T2 (de) 2004-11-11

Family

ID=24416734

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69631169T Expired - Fee Related DE69631169T2 (de) 1996-02-20 1996-10-18 Herstellung von (s)-decahydroisochinolin-3-carbonsäure-t-butylamid

Country Status (10)

Country Link
US (1) US5587481A (de)
EP (1) EP0902781B1 (de)
JP (1) JP2001506575A (de)
KR (1) KR19990076981A (de)
AT (1) ATE256664T1 (de)
AU (1) AU713924B2 (de)
CA (1) CA2238478A1 (de)
DE (1) DE69631169T2 (de)
NO (1) NO312293B1 (de)
WO (1) WO1997030976A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2135171T5 (es) * 1995-06-30 2006-03-16 Ajinomoto Co., Inc. Procedimiento para producir amidas opticamente activas.
IT1301825B1 (it) * 1998-06-26 2000-07-07 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
CZ299699B6 (cs) * 1998-12-14 2008-10-22 Sk Corporation Zpusob výroby [3S-(3alfa, 4alfabeta, 8alfabeta)]-N-terc-butyl-dekahydro-3-izochinolinkarboxamidu s vysokým optickým výtežkem
KR100277723B1 (ko) 1998-12-14 2001-01-15 남창우 광학적으로 순수한 데카하이드로이소퀴놀린카르복사미드의 연속제조공정
IT1313682B1 (it) * 1999-11-25 2002-09-09 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
IT1318986B1 (it) * 2000-10-09 2003-09-19 Archimica S P A Ora Clariant L Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
US8627573B2 (en) * 2002-10-05 2014-01-14 Braun Gmbh Hair-removing device
BRPI0410125A (pt) * 2003-05-08 2006-05-09 Pfizer intermediários úteis para a sìntese de inibidores de protease de hiv, e métodos para os preparar
CN1300115C (zh) * 2004-03-26 2007-02-14 厦门大学 一种合成1，2，3，4－四氢异喹啉衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
WO1993001174A1 (en) * 1991-07-08 1993-01-21 Glaxo Group Limited Thiazolidine derivatives and their use as anti-viral compounds
US5256783A (en) * 1991-09-18 1993-10-26 Hoffmann-La Roche Inc. Method for producing 2-isoquinoline compounds
US5380849A (en) * 1992-11-09 1995-01-10 Merck & Co., Inc. Process for optically pure decahydroisoqiunolines
ES2135171T5 (es) * 1995-06-30 2006-03-16 Ajinomoto Co., Inc. Procedimiento para producir amidas opticamente activas.

Also Published As

Publication number Publication date
EP0902781B1 (de) 2003-12-17
ATE256664T1 (de) 2004-01-15
CA2238478A1 (en) 1997-08-28
NO983803L (no) 1998-10-19
NO312293B1 (no) 2002-04-22
AU713924B2 (en) 1999-12-16
JP2001506575A (ja) 2001-05-22
WO1997030976A1 (en) 1997-08-28
AU7449496A (en) 1997-09-10
NO983803D0 (no) 1998-08-19
KR19990076981A (ko) 1999-10-25
US5587481A (en) 1996-12-24
EP0902781A1 (de) 1999-03-24
EP0902781A4 (de) 2000-07-19
DE69631169T2 (de) 2004-11-11

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee