ATE256664T1 - Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid - Google Patents

Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid

Info

Publication number
ATE256664T1
ATE256664T1 AT96936615T AT96936615T ATE256664T1 AT E256664 T1 ATE256664 T1 AT E256664T1 AT 96936615 T AT96936615 T AT 96936615T AT 96936615 T AT96936615 T AT 96936615T AT E256664 T1 ATE256664 T1 AT E256664T1
Authority
AT
Austria
Prior art keywords
tic
butylamide
carboxylic acid
decahydroisocinoline
production
Prior art date
Application number
AT96936615T
Other languages
English (en)
Inventor
David R Allen
Scott Jenkins
Loraine Klein
Robert Erickson
Diana Froen
Original Assignee
Pcbu Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pcbu Services Inc filed Critical Pcbu Services Inc
Application granted granted Critical
Publication of ATE256664T1 publication Critical patent/ATE256664T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT96936615T 1996-02-20 1996-10-18 Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid ATE256664T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/603,744 US5587481A (en) 1996-02-20 1996-02-20 Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
PCT/US1996/016628 WO1997030976A1 (en) 1996-02-20 1996-10-18 Preparation of (s)-decahydroisoquinoline-3-carboxylic acid t-butylamide

Publications (1)

Publication Number Publication Date
ATE256664T1 true ATE256664T1 (de) 2004-01-15

Family

ID=24416734

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96936615T ATE256664T1 (de) 1996-02-20 1996-10-18 Herstellung von (s)-decahydroisochinolin-3- carbonsäure-t-butylamid

Country Status (10)

Country Link
US (1) US5587481A (de)
EP (1) EP0902781B1 (de)
JP (1) JP2001506575A (de)
KR (1) KR19990076981A (de)
AT (1) ATE256664T1 (de)
AU (1) AU713924B2 (de)
CA (1) CA2238478A1 (de)
DE (1) DE69631169T2 (de)
NO (1) NO312293B1 (de)
WO (1) WO1997030976A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0751128B2 (de) † 1995-06-30 2005-08-31 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Amiden
IT1301825B1 (it) * 1998-06-26 2000-07-07 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
CZ299699B6 (cs) * 1998-12-14 2008-10-22 Sk Corporation Zpusob výroby [3S-(3alfa, 4alfabeta, 8alfabeta)]-N-terc-butyl-dekahydro-3-izochinolinkarboxamidu s vysokým optickým výtežkem
KR100277723B1 (ko) 1998-12-14 2001-01-15 남창우 광학적으로 순수한 데카하이드로이소퀴놀린카르복사미드의 연속제조공정
IT1313682B1 (it) * 1999-11-25 2002-09-09 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
IT1318986B1 (it) * 2000-10-09 2003-09-19 Archimica S P A Ora Clariant L Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
US8627573B2 (en) * 2002-10-05 2014-01-14 Braun Gmbh Hair-removing device
BRPI0410125A (pt) * 2003-05-08 2006-05-09 Pfizer intermediários úteis para a sìntese de inibidores de protease de hiv, e métodos para os preparar
CN1300115C (zh) * 2004-03-26 2007-02-14 厦门大学 一种合成1，2，3，4－四氢异喹啉衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
AU2228992A (en) * 1991-07-08 1993-02-11 Glaxo Group Limited Thiazolidine derivatives and their use as anti-viral compounds
US5256783A (en) * 1991-09-18 1993-10-26 Hoffmann-La Roche Inc. Method for producing 2-isoquinoline compounds
US5380849A (en) * 1992-11-09 1995-01-10 Merck & Co., Inc. Process for optically pure decahydroisoqiunolines
EP0751128B2 (de) * 1995-06-30 2005-08-31 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Amiden

Also Published As

Publication number Publication date
EP0902781A1 (de) 1999-03-24
US5587481A (en) 1996-12-24
CA2238478A1 (en) 1997-08-28
DE69631169T2 (de) 2004-11-11
DE69631169D1 (de) 2004-01-29
NO983803D0 (no) 1998-08-19
NO312293B1 (no) 2002-04-22
EP0902781A4 (de) 2000-07-19
WO1997030976A1 (en) 1997-08-28
EP0902781B1 (de) 2003-12-17
NO983803L (no) 1998-10-19
JP2001506575A (ja) 2001-05-22
AU713924B2 (en) 1999-12-16
AU7449496A (en) 1997-09-10
KR19990076981A (ko) 1999-10-25

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