IT1313682B1 - Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide. - Google Patents

Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.

Info

Publication number
IT1313682B1
IT1313682B1 IT1999MI002457A ITMI992457A IT1313682B1 IT 1313682 B1 IT1313682 B1 IT 1313682B1 IT 1999MI002457 A IT1999MI002457 A IT 1999MI002457A IT MI992457 A ITMI992457 A IT MI992457A IT 1313682 B1 IT1313682 B1 IT 1313682B1
Authority
IT
Italy
Prior art keywords
tetraidroisochinolin
terbutyl
carboxyamide
procedure
preparation
Prior art date
Application number
IT1999MI002457A
Other languages
English (en)
Inventor
Pietro Bellani
Aldo Banfi
Original Assignee
Archimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimica Spa filed Critical Archimica Spa
Publication of ITMI992457A0 publication Critical patent/ITMI992457A0/it
Priority to IT1999MI002457A priority Critical patent/IT1313682B1/it
Priority to US09/478,657 priority patent/US6433177B1/en
Priority to EP00811108A priority patent/EP1104755B1/en
Priority to ES00811108T priority patent/ES2228442T3/es
Priority to AT00811108T priority patent/ATE278672T1/de
Priority to DE60014556T priority patent/DE60014556T2/de
Priority to KR1020000069801A priority patent/KR20010051886A/ko
Priority to HU0004717A priority patent/HUP0004717A2/hu
Priority to JP2000357141A priority patent/JP2001163860A/ja
Publication of ITMI992457A1 publication Critical patent/ITMI992457A1/it
Application granted granted Critical
Publication of IT1313682B1 publication Critical patent/IT1313682B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
IT1999MI002457A 1999-11-25 1999-11-25 Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide. IT1313682B1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT1999MI002457A IT1313682B1 (it) 1999-11-25 1999-11-25 Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
US09/478,657 US6433177B1 (en) 1999-11-25 2000-01-06 Process for the preparation of (S)-N-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
AT00811108T ATE278672T1 (de) 1999-11-25 2000-11-22 Verfahren zur herstellung von (s)-n-tertbutyl-1,2,3,4- tetrahydroisochinolin-3-carboxamid
ES00811108T ES2228442T3 (es) 1999-11-25 2000-11-22 Procedimiento para la preparacion de (s)-n-terc-butil- 1,2,3,4-tetrahidroisoquinolin-3- carboxamida.
EP00811108A EP1104755B1 (en) 1999-11-25 2000-11-22 Process for the preparation of (S)-N-tertbutyl-1,2,3,4- tetrahydroisoquinoline-3-carboxamide
DE60014556T DE60014556T2 (de) 1999-11-25 2000-11-22 Verfahren zur Herstellung von (S)-N-tertbutyl-1,2,3,4- Tetrahydroisochinolin-3-carboxamid
KR1020000069801A KR20010051886A (ko) 1999-11-25 2000-11-23 (에스)-엔-3급-부틸-1,2,3,4-테트라하이드로이소퀴놀린-3-카복스아미드의 제조 방법
HU0004717A HUP0004717A2 (hu) 1999-11-25 2000-11-24 Eljárás (S)-N-(terc-butil)-1,2,3,4-tetrahidroizokinolin-3-karboxamid előállítására
JP2000357141A JP2001163860A (ja) 1999-11-25 2000-11-24 （Ｓ）−Ｎ−ｔｅｒｔ−ブチル−１，２，３，４−テトラヒドロイソキノリン−３−カルボキシアミドの製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002457A IT1313682B1 (it) 1999-11-25 1999-11-25 Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.

Publications (3)

Publication Number Publication Date
ITMI992457A0 ITMI992457A0 (it) 1999-11-25
ITMI992457A1 ITMI992457A1 (it) 2001-05-25
IT1313682B1 true IT1313682B1 (it) 2002-09-09

Family

ID=11384015

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI002457A IT1313682B1 (it) 1999-11-25 1999-11-25 Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.

Country Status (9)

Country Link
US (1) US6433177B1 (it)
EP (1) EP1104755B1 (it)
JP (1) JP2001163860A (it)
KR (1) KR20010051886A (it)
AT (1) ATE278672T1 (it)
DE (1) DE60014556T2 (it)
ES (1) ES2228442T3 (it)
HU (1) HUP0004717A2 (it)
IT (1) IT1313682B1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1300115C (zh) * 2004-03-26 2007-02-14 厦门大学 一种合成1，2，3，4－四氢异喹啉衍生物的方法
CN101384590A (zh) * 2005-12-22 2009-03-11 先灵公司 作为凝血酶受体拮抗剂的唑并异喹啉

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
ES2135171T5 (es) * 1995-06-30 2006-03-16 Ajinomoto Co., Inc. Procedimiento para producir amidas opticamente activas.
JP3204368B2 (ja) * 1995-06-30 2001-09-04 味の素株式会社 光学活性アミド類の製法
US5587481A (en) * 1996-02-20 1996-12-24 The Monsanto Company Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
JPH10291979A (ja) 1997-04-21 1998-11-04 Ichikawa Gosei Kagaku Kk １，２，３，４−テトラヒドロイソキノリン−３−カルボン酸ターシャリーブチルアミドの製造方法
IT1301825B1 (it) * 1998-06-26 2000-07-07 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.

Also Published As

Publication number Publication date
ITMI992457A1 (it) 2001-05-25
US6433177B1 (en) 2002-08-13
ITMI992457A0 (it) 1999-11-25
EP1104755A1 (en) 2001-06-06
HUP0004717A2 (hu) 2002-11-28
HU0004717D0 (it) 2001-02-28
DE60014556D1 (de) 2004-11-11
ATE278672T1 (de) 2004-10-15
EP1104755B1 (en) 2004-10-06
JP2001163860A (ja) 2001-06-19
ES2228442T3 (es) 2005-04-16
DE60014556T2 (de) 2005-02-03
KR20010051886A (ko) 2001-06-25

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