DE60014556D1 - Verfahren zur Herstellung von (S)-N-tertbutyl-1,2,3,4- Tetrahydroisochinolin-3-carboxamid - Google Patents

Verfahren zur Herstellung von (S)-N-tertbutyl-1,2,3,4- Tetrahydroisochinolin-3-carboxamid

Info

Publication number
DE60014556D1
DE60014556D1 DE60014556T DE60014556T DE60014556D1 DE 60014556 D1 DE60014556 D1 DE 60014556D1 DE 60014556 T DE60014556 T DE 60014556T DE 60014556 T DE60014556 T DE 60014556T DE 60014556 D1 DE60014556 D1 DE 60014556D1
Authority
DE
Germany
Prior art keywords
tetrahydroisoquinoline
carboxamide
tert
butyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60014556T
Other languages
English (en)
Other versions
DE60014556T2 (de
Inventor
Pietro Bellani
Aldo Banfi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archimica SpA
Original Assignee
Clariant LSM Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant LSM Italia SpA filed Critical Clariant LSM Italia SpA
Publication of DE60014556D1 publication Critical patent/DE60014556D1/de
Application granted granted Critical
Publication of DE60014556T2 publication Critical patent/DE60014556T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60014556T 1999-11-25 2000-11-22 Verfahren zur Herstellung von (S)-N-tertbutyl-1,2,3,4- Tetrahydroisochinolin-3-carboxamid Expired - Fee Related DE60014556T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI002457A IT1313682B1 (it) 1999-11-25 1999-11-25 Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
ITMI992457 1999-11-25

Publications (2)

Publication Number Publication Date
DE60014556D1 true DE60014556D1 (de) 2004-11-11
DE60014556T2 DE60014556T2 (de) 2005-02-03

Family

ID=11384015

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60014556T Expired - Fee Related DE60014556T2 (de) 1999-11-25 2000-11-22 Verfahren zur Herstellung von (S)-N-tertbutyl-1,2,3,4- Tetrahydroisochinolin-3-carboxamid

Country Status (9)

Country Link
US (1) US6433177B1 (de)
EP (1) EP1104755B1 (de)
JP (1) JP2001163860A (de)
KR (1) KR20010051886A (de)
AT (1) ATE278672T1 (de)
DE (1) DE60014556T2 (de)
ES (1) ES2228442T3 (de)
HU (1) HUP0004717A2 (de)
IT (1) IT1313682B1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1300115C (zh) * 2004-03-26 2007-02-14 厦门大学 一种合成1,2,3,4-四氢异喹啉衍生物的方法
JP2009521458A (ja) * 2005-12-22 2009-06-04 シェーリング コーポレイション トロンビン受容体アンタゴニストとしてのオキサゾロイソキノリン誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
EP0751128B2 (de) * 1995-06-30 2005-08-31 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Amiden
JP3204368B2 (ja) * 1995-06-30 2001-09-04 味の素株式会社 光学活性アミド類の製法
US5587481A (en) * 1996-02-20 1996-12-24 The Monsanto Company Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
JPH10291979A (ja) 1997-04-21 1998-11-04 Ichikawa Gosei Kagaku Kk 1,2,3,4−テトラヒドロイソキノリン−3−カルボン酸ターシャリーブチルアミドの製造方法
IT1301825B1 (it) * 1998-06-26 2000-07-07 Archimica Spa Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.

Also Published As

Publication number Publication date
IT1313682B1 (it) 2002-09-09
ITMI992457A1 (it) 2001-05-25
JP2001163860A (ja) 2001-06-19
EP1104755A1 (de) 2001-06-06
EP1104755B1 (de) 2004-10-06
KR20010051886A (ko) 2001-06-25
ITMI992457A0 (it) 1999-11-25
ATE278672T1 (de) 2004-10-15
HU0004717D0 (de) 2001-02-28
US6433177B1 (en) 2002-08-13
HUP0004717A2 (hu) 2002-11-28
ES2228442T3 (es) 2005-04-16
DE60014556T2 (de) 2005-02-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ARCHIMICA S.R.L., MILANO, IT

8339 Ceased/non-payment of the annual fee