DE69629010D1 - Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen - Google Patents

Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen

Info

Publication number
DE69629010D1
DE69629010D1 DE69629010T DE69629010T DE69629010D1 DE 69629010 D1 DE69629010 D1 DE 69629010D1 DE 69629010 T DE69629010 T DE 69629010T DE 69629010 T DE69629010 T DE 69629010T DE 69629010 D1 DE69629010 D1 DE 69629010D1
Authority
DE
Germany
Prior art keywords
fluid
container
biochemically reactive
fibrine
linked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69629010T
Other languages
English (en)
Other versions
DE69629010T2 (de
Inventor
Yves Delmotte
Genevieve Krack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7751566&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69629010(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter International Inc filed Critical Baxter International Inc
Priority to DE69629010T priority Critical patent/DE69629010T2/de
Publication of DE69629010D1 publication Critical patent/DE69629010D1/de
Application granted granted Critical
Publication of DE69629010T2 publication Critical patent/DE69629010T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/046—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A61F2310/00377—Fibrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Surgical Instruments (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Magnetically Actuated Valves (AREA)
  • Medicinal Preparation (AREA)
DE69629010T 1995-01-16 1996-01-16 Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen Revoked DE69629010T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69629010T DE69629010T2 (de) 1995-01-16 1996-01-16 Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19501067 1995-01-16
DE19501067 1995-01-16
DE69629010T DE69629010T2 (de) 1995-01-16 1996-01-16 Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
PCT/EP1996/000160 WO1996022115A1 (en) 1995-01-16 1996-01-16 Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions

Publications (2)

Publication Number Publication Date
DE69629010D1 true DE69629010D1 (de) 2003-08-14
DE69629010T2 DE69629010T2 (de) 2004-04-15

Family

ID=7751566

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69629010T Revoked DE69629010T2 (de) 1995-01-16 1996-01-16 Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen

Country Status (8)

Country Link
US (2) US6074663A (de)
EP (1) EP0804257B1 (de)
JP (1) JPH11502431A (de)
AT (1) ATE244584T1 (de)
AU (1) AU697045B2 (de)
CA (1) CA2207992A1 (de)
DE (1) DE69629010T2 (de)
WO (1) WO1996022115A1 (de)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69629010T2 (de) * 1995-01-16 2004-04-15 Baxter International Inc., Deerfield Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
US6965014B1 (en) 1996-01-16 2005-11-15 Baxter International Inc. Fibrin material and method for producing and using the same
US6599515B1 (en) 1995-01-16 2003-07-29 Baxter International Inc. Fibrin porous structure
US6835186B1 (en) * 1995-01-16 2004-12-28 Baxter International, Inc. Mechanical breakup unit for biochemically reactive fluid delivery device
US20020131933A1 (en) * 1996-01-16 2002-09-19 Yves Delmotte Biopolymer membrane and methods for its preparation
DE29723807U1 (de) * 1996-04-30 1999-11-04 Medtronic, Inc., Minneapolis, Minn. Autologe Fibrin-Blutstillungsmittel
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
EP0917444A1 (de) 1996-07-12 1999-05-26 Baxter Travenol Laboratories, Inc. Fibrinliefervorrichtung und verfahren zur erzeugung von fibrin auf einer fläche
US8603511B2 (en) * 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US20090324721A1 (en) * 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
EP1009472A4 (de) 1997-04-14 2009-12-02 Baxter Int Gerät zum medizinischen saugen und gebrauchsverfahren
US6733472B1 (en) 1997-04-14 2004-05-11 Baxter International Inc. Sealant applicator tip and application method
US6331172B1 (en) 1997-04-14 2001-12-18 Baxter International Inc. Applicator for dispensing measured quantities with use of controlled suction
US6461361B1 (en) 1998-05-01 2002-10-08 Baxter International Inc. Gas-driven spraying of mixed sealant agents
ATE367181T1 (de) * 1998-05-21 2007-08-15 Baxter Int Dichtungsmittelapplikator sowie verfahren zum säubern mittels impulsen
US6475183B1 (en) * 1998-06-03 2002-11-05 Baxter International Inc. Direct dual filling device for sealing agents
US7347850B2 (en) * 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
JP4115669B2 (ja) * 1998-10-01 2008-07-09 バクスター・インターナショナル・インコーポレイテッド 改良された成分混合用カテーテル
US20020173748A1 (en) * 1998-10-29 2002-11-21 Mcconnell Susan Reservoir connector
DK1642615T3 (da) * 1998-10-29 2011-05-30 Medtronic Minimed Inc Reservoir-forbindelsesdel
BE1012536A3 (fr) 1998-11-04 2000-12-05 Baxter Int Element muni d'une couche de fibrine sa preparation et son utilisation.
US7276235B2 (en) 1998-11-18 2007-10-02 Zlb Behring Gmbh Tissue glue with improved antiadhesive properties
DE10025001A1 (de) * 2000-05-22 2001-11-29 Aventis Behring Gmbh Gewebekleber mit verbesserten anti-adhäsiven Eigenschaften
KR100858830B1 (ko) 1998-11-18 2008-09-17 체에스엘 베링 게엠베하 조직 접합제용의 안정화된 단백질 제제
US20080114092A1 (en) * 1998-12-04 2008-05-15 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US7572769B2 (en) 1998-12-23 2009-08-11 Csl Behring Gmbh Fibrin adhesive granulate and method for its preparation
CA2373738A1 (en) * 1999-06-01 2000-12-07 Bristol-Myers Squibb Company Fibrin polymer structure
US6491201B1 (en) * 2000-02-22 2002-12-10 Power Medical Interventions, Inc. Fluid delivery mechanism for use with anastomosing, stapling, and resecting instruments
US7695485B2 (en) 2001-11-30 2010-04-13 Power Medical Interventions, Llc Surgical device
US8025199B2 (en) 2004-02-23 2011-09-27 Tyco Healthcare Group Lp Surgical cutting and stapling device
NZ337318A (en) * 1999-08-18 2002-07-26 Interag Dispensing apparatus for dispensing same or different materials for at least two reservoirs
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
JP2003521326A (ja) * 2000-02-03 2003-07-15 ティシュームド リミテッド 外科手術に起因する穿刺を閉塞するための装置
US6488197B1 (en) * 2000-02-22 2002-12-03 Power Medical Interventions, Inc. Fluid delivery device for use with anastomosing resecting and stapling instruments
US8016855B2 (en) 2002-01-08 2011-09-13 Tyco Healthcare Group Lp Surgical device
DE60138020D1 (de) * 2000-04-28 2009-04-30 Fziomed Inc Haemostatische zusammenstellung von polysäuren und polyalkylenoxyden und deren verwendungsmethoden
US20030209612A1 (en) * 2000-07-17 2003-11-13 Kevin Hahnen Spray head for applying a multi-component mixture
WO2002034304A1 (en) * 2000-10-23 2002-05-02 Tissuemed Limited Self-adhesive hydratable matrix for topical therapeutic use
CA2325842C (en) 2000-11-02 2007-08-07 Lisa Mckerracher Methods for making and delivering rho-antagonist tissue adhesive formulations to the injured mammalian central and peripheral nervous systems and uses thereof
US7008633B2 (en) * 2000-12-18 2006-03-07 Board Of Regents, The University Of Texas System Local regional chemotherapy and radiotherapy using in situ hydrogel
US7175336B2 (en) 2001-01-26 2007-02-13 Depuy Acromed, Inc. Graft delivery system
US7795218B2 (en) 2001-04-12 2010-09-14 Bioaxone Therapeutique Inc. ADP-ribosyl transferase fusion variant proteins
EP1387703B1 (de) * 2001-05-09 2006-07-26 Baxter International Inc. Fibrinmaterial und verfahren zu seiner herstellung und verwendung
ATE333907T1 (de) * 2001-05-09 2006-08-15 Baxter Int Fibrinmaterial und verfahren zu seiner herstellung und verwendung
AU2002308409B2 (en) * 2001-05-21 2005-12-01 Thoratec Corporation Staged implantation of ventricular assist devices
AUPR514201A0 (en) * 2001-05-21 2001-06-14 Ventrassist Pty Ltd Staged implantation of ventricular assist devices
US6723067B2 (en) * 2001-07-26 2004-04-20 David H. Nielson Apparatus for delivering aerosolized fibrin endoscopically to a wound
US7135189B2 (en) * 2001-08-23 2006-11-14 Boston Scientific Scimed, Inc. Compositions and techniques for localized therapy
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
US9113878B2 (en) 2002-01-08 2015-08-25 Covidien Lp Pinion clip for right angle linear cutter
US8529956B2 (en) * 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
WO2003079985A2 (en) * 2002-03-18 2003-10-02 Carnegie Mellon University Method and apparatus for preparing biomimetic scaffold
US8293530B2 (en) * 2006-10-17 2012-10-23 Carnegie Mellon University Method and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US6863660B2 (en) 2002-03-27 2005-03-08 Hapio Biotech, Inc. Fibrin applicator pistol
US6932833B1 (en) 2002-04-01 2005-08-23 Bobby W. Presley Method and barrier for limiting fluid movement through a tissue rent
NL1020426C2 (nl) * 2002-04-18 2003-10-21 Tno Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen.
US6644365B1 (en) 2002-04-19 2003-11-11 Baxter International, Inc. Tilting direct dual filling device
ES2270045T3 (es) 2002-05-10 2007-04-01 Tyco Healthcare Group Lp Aplicador de material de cierre de heridas y grapadora.
US6936033B2 (en) * 2002-06-14 2005-08-30 Medtronic, Inc. Multiple ratio fluid dispenser
JP2004016045A (ja) * 2002-06-13 2004-01-22 Olympus Corp 培養装置
AU2003239988A1 (en) 2002-06-14 2003-12-31 Power Medical Interventions, Inc. Device for clamping cutting and stapling tissue
US20040138695A1 (en) * 2002-06-18 2004-07-15 Shu-Tung Li Coatings of implants
US20040037866A1 (en) * 2002-08-20 2004-02-26 Semertzides John N. Composition and method for the treatment and prevention of adhesions
US20040126881A1 (en) * 2002-09-06 2004-07-01 Vincent Ronfard Fibrin cell supports and methods of use thereof
US7135027B2 (en) * 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
AU2003302906B2 (en) * 2002-12-11 2009-04-02 Ferrosan Medical Devices A/S Gelatine-based materials as swabs
US7077339B2 (en) * 2003-02-03 2006-07-18 Biomet, Inc. Spray applicator
US20060171970A1 (en) * 2003-02-21 2006-08-03 Cardio Combos Llc Pharmaceutical formulation delivery system
CA2521661A1 (en) * 2003-04-04 2004-10-14 Tissuemed Limited Tissue-adhesive formulations
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20040243044A1 (en) * 2003-06-02 2004-12-02 Penegor Stephen A. Hemostatic wound dressing
US7435237B2 (en) * 2003-06-02 2008-10-14 Boston Scientific Scimed, Inc. Mixing syringes with breakable septums
US20050032205A1 (en) * 2003-08-05 2005-02-10 Smith Sidney T. In vitro cell culture employing a fibrin network in a flexible gas permeable container
US20070131795A1 (en) * 2003-11-07 2007-06-14 Abbate Anthony J Device and method for mixing and dispensing fluid components of a multicomponent composition
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
WO2005072700A2 (en) * 2004-01-30 2005-08-11 Ferrosan A/S Haemostatic sprays and compositions
EP1753860B1 (de) * 2004-02-20 2012-04-11 Isto Technologies Inc. Bandscheibenreparatur und verfahren dafür
US7758654B2 (en) 2004-05-20 2010-07-20 Kensey Nash Corporation Anti-adhesion device
EP1759718A4 (de) * 2004-05-21 2011-03-02 Chemo Sero Therapeut Res Inst Präparat für gewebeschluss
AU2005262070B2 (en) * 2004-07-09 2011-01-27 Ferrosan Medical Devices A/S Haemostatic composition comprising hyaluronic acid
US8206448B2 (en) 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US7597687B2 (en) 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
RU2396985C2 (ru) * 2004-08-03 2010-08-20 Тиссьюмед Лимитед Материалы, обладающие адгезией к тканям
US7490738B2 (en) * 2004-10-01 2009-02-17 Angiotech Pharmaceuticals (Us), Inc. Mixing and dispensing fluid components of a multicomponent composition
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8047407B2 (en) * 2004-10-29 2011-11-01 Spinal Restoration, Inc. Apparatus and method for delivery of biologic sealant
ES2668355T3 (es) * 2005-01-19 2018-05-17 Anika Therapeutics S.R.L. Derivado de ácido hialurónico y células madre neurales para la regeneración de SCI y PNT
US7635343B2 (en) * 2005-04-21 2009-12-22 Arteriocyte Medical Systems, Inc. Fluid dispenser
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1934288A2 (de) * 2005-07-28 2008-06-25 Carnegie Mellon University Biokompatible polymere und verwendungsverfahren
US20070074980A1 (en) * 2005-09-02 2007-04-05 Bankoski Brian R Implant rehydration packages and methods of use
EP1926459B1 (de) 2005-09-19 2015-01-07 Histogenics Corporation Zellunterstützende matrix mit eng definierter, gleichmässig senkrecht und nicht zufällig organisierter porosität und porendichte und verfahren zur herstellung davon
US20090038701A1 (en) * 2006-01-17 2009-02-12 Baxter International Inc. Device, system and method for mixing
ES2348940T3 (es) * 2006-01-17 2010-12-17 Baxter International Inc. Dispositivo, sistema y método de mezcla.
WO2007088402A2 (en) 2006-02-03 2007-08-09 Tissuemed Limited Tissue-adhesive materials
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
CN101516301B (zh) * 2006-08-04 2014-10-15 Stb有限公司 用于处理受伤组织的固体敷料
US8529959B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
WO2008081463A2 (en) * 2007-01-04 2008-07-10 Hepacore Ltd. Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
ES2534292T5 (es) 2007-09-21 2018-07-04 Covidien Lp Dispositivo quirúrgico
AU2008302043B2 (en) 2007-09-21 2013-06-27 Covidien Lp Surgical device
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
US8753670B2 (en) 2008-03-26 2014-06-17 Baxter International Inc. Fibrin foam and process
US8512740B2 (en) * 2008-03-26 2013-08-20 Baxter International Inc. Fibrin foam and process for making
US8128642B2 (en) * 2008-05-02 2012-03-06 Tyco Healthcare Group Lp Fluid delivery system for surgical instruments
US8523805B2 (en) * 2008-10-29 2013-09-03 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
US8177072B2 (en) * 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
BRPI0922524B8 (pt) 2008-12-11 2021-06-22 Baxter Healthcare Sa estrutura semelhante a coágulo de fibrina, e, usos de uma estrutura semelhante a coágulo de fibrina, e de uma preparação de uma estrutura semelhante a coágulo de fibrina
CN102365101A (zh) 2009-03-27 2012-02-29 阿克塔马克斯手术器材有限责任公司 包含聚甘油醛的组织粘合剂和密封剂
WO2010111570A1 (en) 2009-03-27 2010-09-30 E. I. Du Pont De Nemours And Company Polyglycerol aldehydes
US20100246316A1 (en) * 2009-03-31 2010-09-30 Baxter International Inc. Dispenser, kit and mixing adapter
EP2448604B1 (de) 2009-07-02 2016-03-23 Actamax Surgical Materials LLC Hydrogel-gewebekleber zum medizinischen gebrauch
TWI434698B (zh) * 2009-08-14 2014-04-21 Eu Sol Biotech Co Ltd 人類酸性纖維母細胞生長因子之醫藥用途
EP2475308A1 (de) 2009-09-08 2012-07-18 Baxter International Inc Wiederherstellungs- und applikatorsystem für ein wundheilprodukt
WO2011035020A1 (en) * 2009-09-18 2011-03-24 Bioinspire Technologies, Inc. Free-standing biodegradable patch
US9271925B2 (en) * 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
US8641661B2 (en) * 2010-01-05 2014-02-04 Baxter International Inc. Mixing system, kit and mixer adapter
CA2726566A1 (en) * 2010-01-11 2011-07-11 Baxter International Inc. Pipette system, pipette tip assembly and kit
MX2012008845A (es) * 2010-01-28 2012-09-28 Omrix Biopharmaceuticals Ltd Metodo para sellado de fibrina mejorado.
US9211554B2 (en) 2010-06-30 2015-12-15 Actamax Surgical Materials, Llc Self-contained hand-held direct drive device for dispensing a two-part adhesive aerosol
US8678238B2 (en) 2010-06-30 2014-03-25 Actamax Surgical Materials, Llc Self-contained hand-held yoke-connected device for dispensing a two-part adhesive aerosol
US20120065666A1 (en) * 2010-09-10 2012-03-15 E. I. Du Pont De Nemours And Company Seal-less device for dispensing microliter quantities of a material into a site
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
US9308219B2 (en) * 2011-06-30 2016-04-12 Collagen Matrix, Inc. Flat self-curling permeable sheet membrane
US8999376B2 (en) 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
US11109849B2 (en) 2012-03-06 2021-09-07 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
DE102012104530A1 (de) * 2012-05-25 2013-11-28 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Verwendung einer biokompatiblen Zusammensetzung
EP2825216B1 (de) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Trockene blutstillende zusammensetzung
US9381005B2 (en) 2012-10-26 2016-07-05 Baxter International Inc. Spray head for two component mixer
RU2700162C2 (ru) 2013-06-21 2019-09-13 Ферросан Медикал Дивайсиз А/С Расширенная под вакуумом сухая композиция и шприц для ее сохранения
EP3013294B1 (de) 2013-06-28 2019-09-25 3M Innovative Properties Company Fibrinbeschichteter wundverband
EP3027659B1 (de) 2013-07-29 2020-12-09 Actamax Surgical Materials LLC Gewebeklebstoff mit niedriger schwellung und dichtungsmittelzusammensetzungen
US10111980B2 (en) 2013-12-11 2018-10-30 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9743917B2 (en) 2014-12-19 2017-08-29 Cohera Medical, Inc. Devices for applying surgical sealants
BR112017013565B1 (pt) 2014-12-24 2021-12-28 Ferrosan Medical Devices A/S Seringa para retenção e mistura de primeira e segunda substâncias
JP6793113B2 (ja) 2015-03-12 2020-12-02 Ｋｍバイオロジクス株式会社 脱細胞化組織を用いた癒着防止材及び代用生体膜
JP6810052B2 (ja) 2015-03-27 2021-01-06 スリーエム イノベイティブ プロパティズ カンパニー フィブリン組成物、方法及び創傷物品
AU2016256858B2 (en) 2015-05-06 2020-10-08 Zoetis Services Llc Hydrogel formulation with mild adhesion
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
EP3331577A4 (de) 2015-08-07 2019-07-17 Xcede Technologies, Inc. Klebstoffzusammensetzungen und zugehörige verfahren
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
US9572555B1 (en) * 2015-09-24 2017-02-21 Ethicon, Inc. Spray or drip tips having multiple outlet channels
CA3002214C (en) 2015-11-03 2022-01-04 Zoetis Services Llc Sol-gel polymer composites and uses thereof
US10441761B2 (en) 2016-07-01 2019-10-15 Boston Scientific Scimed, Inc. Delivery devices and methods
EP3522941A4 (de) 2016-10-05 2020-06-17 3M Innovative Properties Company Fibrinogenzusammensetzung, verfahren und wundartikel
WO2018067628A1 (en) 2016-10-05 2018-04-12 3M Innovative Properties Company Fibrin composition comprising carrier material, method and wound articles
CA3057856A1 (en) 2017-04-20 2018-10-25 Zoetis Services Llc Veterinary compositions for use in treating mastitis, and associated methods
JP2021504435A (ja) 2017-12-01 2021-02-15 ゾエティス・サービシーズ・エルエルシー ヒドロゲル組成物及びその使用
US11766546B2 (en) 2018-01-31 2023-09-26 Boston Scientific Scimed, Inc. Apparatuses and methods for delivering powdered agents
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
IL261190A (en) 2018-08-16 2019-01-31 Omrix Biopharmaceuticals Ltd Stable liquid preparations of thrombin
IL263679A (en) * 2018-12-12 2019-03-31 Omrix Biopharmaceuticals Ltd Kits, methods, and ingredients for preventing tissue adhesion
WO2020121290A1 (en) * 2018-12-12 2020-06-18 Omrix Biopharmaceuticals Ltd. High concentrated protein compositions for preventing tissue adhesion
KR102673609B1 (ko) 2019-08-01 2024-06-10 케이엠 바이올로직스 가부시키가이샤 생체 적합성 고분자를 사용한 조직의 섬유화 억제제
IT202100025664A1 (it) * 2021-10-07 2023-04-07 Consiglio Nazionale Ricerche Metodo per la fabbricazione di un patch medicale per il rilascio locale e controllato di sostanze bioattive per il trattamento di ulcere croniche, e patch medicale ottenuto con tale metodo

Family Cites Families (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533004A (en) * 1943-10-27 1950-12-05 John D Ferry Fibrin clots and methods for preparing the same
US2576006A (en) * 1947-11-29 1951-11-20 Research Corp Methods of forming shaped fibrin products
US3523807A (en) * 1966-11-25 1970-08-11 Mihaly Gerendas Method of making a cross-linked fibrin prosthesis
US3641240A (en) * 1968-09-27 1972-02-08 Wyandotte Chemicals Corp Method for the treatment of an embolus or thrombus
US3723244A (en) * 1971-01-18 1973-03-27 Atomic Energy Commission Fibrous fibrin sheet and method for producing same
SE452109B (sv) * 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US4537767A (en) * 1973-01-29 1985-08-27 Pharmacia Aktiebolag Method for cleansing fluid discharging skin surfaces, wounds and mucous membranes and means for carrying out the method
US4016877A (en) * 1976-02-23 1977-04-12 Avicon, Inc. Fibrous collagen derived web having hemostatic and wound sealing properties
US4148664A (en) * 1976-05-10 1979-04-10 Avicon, Inc. Preparation of fibrous collagen product having hemostatic and wound sealing properties
US4066083A (en) * 1976-06-03 1978-01-03 Pentapharm A.G. Sterile surgical collagen product
US4116898A (en) * 1977-01-31 1978-09-26 Becton, Dickinson And Company Non-thrombogenic articles
US4238480A (en) * 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
AT359652B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
US4675361A (en) * 1980-02-29 1987-06-23 Thoratec Laboratories Corp. Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
AT366916B (de) * 1980-04-02 1982-05-25 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen
EP0068149A3 (de) * 1981-06-25 1983-07-20 Serapharm GmbH & Co. KG Fibrinogen-haltiges Trockenpräparat, dessen Herstellung und Verwendung
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
EP0085166B1 (de) * 1981-12-30 1986-06-25 New York Blood Center, Inc. Filter und Verfahren zu seiner Herstellung
SE430218B (sv) * 1981-12-30 1983-10-31 Blombaeck E G B Filter och sett att framstella ett sadant
US4578067A (en) * 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
DE3234084A1 (de) * 1982-09-14 1984-03-15 B. Braun Melsungen Ag, 3508 Melsungen Pharmazeutische zubereitungen zur behandlung von unerwuenschten verwachsungen sowie deren verwendung
DE3248188A1 (de) * 1982-12-27 1984-06-28 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines kollagen-vlieses
US4548736A (en) * 1983-08-29 1985-10-22 Wisconsin Alumni Research Foundation Preparation of protein films
US4600574A (en) * 1984-03-21 1986-07-15 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of producing a tissue adhesive
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
AT379311B (de) * 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
EP0166263A1 (de) * 1984-05-31 1986-01-02 Green Cross Corporation Füllmaterial für Knochendefekte oder Knochenhohlräume, Kit oder Set zur Herstellung dieses Füllmaterials
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US5223420A (en) * 1985-03-01 1993-06-29 Institut National De La Sante Et De La Recherche Medicale Elastin-based product, a procedure for its preparation and its biological applications; in particular as biomaterials and artificial supports
WO1986007541A1 (en) * 1985-06-19 1986-12-31 Yasushi Zyo Composition which can impart antithrombotic ability and medical apparatus to be in contact with blood
US4690684A (en) * 1985-07-12 1987-09-01 C. R. Bard, Inc. Meltable stent for anastomosis
JPS6229532A (ja) * 1985-07-31 1987-02-07 Koken:Kk 抗血栓性医用材料及びその製造方法
US5002551A (en) * 1985-08-22 1991-03-26 Johnson & Johnson Medical, Inc. Method and material for prevention of surgical adhesions
US5049393A (en) * 1986-01-07 1991-09-17 Baylor College Of Medicine Anti-thrombogenic elastomer and objects and prostheses made therefrom
US4786556A (en) * 1986-03-24 1988-11-22 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
US4720512A (en) * 1986-03-24 1988-01-19 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
US4760131A (en) * 1986-04-23 1988-07-26 Collagen Corporation Wound-healing composition
US4840626A (en) * 1986-09-29 1989-06-20 Johnson & Johnson Patient Care, Inc. Heparin-containing adhesion prevention barrier and process
DE3751254D1 (de) * 1986-10-31 1995-05-24 Nippon Zeon Co Wundverband.
DE3722904A1 (de) * 1987-01-09 1988-07-21 Harald Maslanka Injektionseinrichtung mit doppelkanuele fuer ein endoskop
US5080893A (en) * 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US5244799A (en) * 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US4882148A (en) * 1987-06-18 1989-11-21 Corvita Corporation Crack prevention and improved thrombogenicity of implanted prostheses by sulfonation
DE3874440T2 (de) * 1987-07-14 1993-01-28 Sankyo Co Zusammensetzung zur herstellung von antithrombotischen medizinischen erzeugnissen.
US5260420A (en) * 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US4978336A (en) * 1987-09-29 1990-12-18 Hemaedics, Inc. Biological syringe system
US5364622A (en) * 1987-12-04 1994-11-15 Dr. Karl Thomae Gmbh Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel
US5201745A (en) * 1988-03-15 1993-04-13 Imedex Visceral surgery patch
US5140016A (en) * 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
US5182317A (en) * 1988-06-08 1993-01-26 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US4874368A (en) * 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4948540A (en) * 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
US5112615A (en) * 1988-08-03 1992-05-12 New England Deaconess Hospital Corporation Soluble hirudin conjugates
US5167960A (en) * 1988-08-03 1992-12-01 New England Deaconess Hospital Corporation Hirudin-coated biocompatible substance
US5126140A (en) * 1988-08-03 1992-06-30 New England Deaconess Hospital Corporation Thrombomodulin-coated bicompatible substance
US5019393A (en) * 1988-08-03 1991-05-28 New England Deaconess Hospital Corporation Biocompatible substance with thromboresistance
US5213580A (en) * 1988-08-24 1993-05-25 Endoluminal Therapeutics, Inc. Biodegradable polymeric endoluminal sealing process
US5053048A (en) * 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US4911926A (en) * 1988-11-16 1990-03-27 Mediventures Inc. Method and composition for reducing postsurgical adhesions
ZA899326B (en) * 1988-12-07 1991-08-28 Johnson & Johnson Patient Care Low molecular weight heparin,heparinoid and hexuronyl hexosaminoglycan sulfate containing adhesion prevention barrier and process
DE3841397A1 (de) * 1988-12-08 1990-06-21 Melzer Wolfgang Poroeser resorbierbarer arzneistofftraeger
JPH05501814A (ja) * 1989-08-10 1993-04-08 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 組織接着剤成分の医療用送り出しシステム
US5116315A (en) * 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US5071664A (en) * 1989-10-20 1991-12-10 Brown Sand T Method of removing sulfites from standard wine
US5525348A (en) * 1989-11-02 1996-06-11 Sts Biopolymers, Inc. Coating compositions comprising pharmaceutical agents
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
WO1991017724A1 (en) * 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
FR2663226B1 (fr) * 1990-06-15 1994-11-18 Fondation Nale Transfusion San Colle biologique fluide.
US5455040A (en) * 1990-07-26 1995-10-03 Case Western Reserve University Anticoagulant plasma polymer-modified substrate
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5209776A (en) * 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5173295A (en) * 1990-10-05 1992-12-22 Advance Biofactures Of Curacao, N.V. Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
AU8702491A (en) * 1990-11-08 1992-05-14 Matrix Pharmaceutical, Inc. Fibrin/collagen membrane material for biomedical use
US5486357A (en) * 1990-11-08 1996-01-23 Cordis Corporation Radiofrequency plasma biocompatibility treatment of inside surfaces
DE69228957T2 (de) * 1991-01-16 1999-10-07 Toyo Boseki K.K., Osaka Blutverträgliches Material
US5156613A (en) * 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
CH681693A5 (de) * 1991-02-28 1993-05-14 Pentapharm Ag
DE69201193T2 (de) * 1991-05-31 1995-09-07 Baxter International Inc., Deerfield, Ill. Schaumdrückende gerinnungsbeständige beschichtung.
JPH06500802A (ja) * 1991-06-14 1994-01-27 アムジエン・インコーポレーテツド コラーゲンフィルムによるタンパクのドラッグ・デリバリー
SE9101853D0 (sv) * 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
FR2679778B1 (fr) * 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
EP0534178B1 (de) * 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Verbesserter Gewebekleber, zubereitet aus Kryopräzipitat
US5368563A (en) * 1991-12-18 1994-11-29 Micromedics, Inc. Sprayer assembly for physiologic glue
US5376376A (en) * 1992-01-13 1994-12-27 Li; Shu-Tung Resorbable vascular wound dressings
GB9206509D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
US5272074A (en) * 1992-04-23 1993-12-21 Mcmaster University Fibrin coated polymer surfaces
US5376692A (en) * 1992-05-15 1994-12-27 Purdue Research Foundation Method of binding using irradiation and product with albumin bound to biomaterials
FR2692582B1 (fr) * 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
IL106293A0 (en) * 1992-07-18 1993-11-15 Opperbas Holding Bv Two-component fibrin-glue composition for improving in vitro fertilization
CA2124320C (en) * 1992-09-26 2007-02-06 Nobuto Fukunaga Applicator for applying a biocompatible adhesive
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
US5278200A (en) * 1992-10-30 1994-01-11 Medtronic, Inc. Thromboresistant material and articles
US5397816A (en) * 1992-11-17 1995-03-14 Ethicon, Inc. Reinforced absorbable polymers
DE4304716A1 (de) * 1993-02-16 1994-08-18 Melzer Wolfgang Lokal applizierbares Arzneimittel mit verzögerter Freisetzung
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
JPH08512215A (ja) * 1993-03-30 1996-12-24 オパーバス・ホールディング・ビー・ブイ 二成分フィブリングルー
AT400675B (de) * 1993-10-18 1996-02-26 Immuno Ag Spritzengarnitur zur aufbewahrung und applikation eines mehrkomponentenmaterials, spritzenvorrichtung und betätigungseinrichtung hiefür sowie verfahren zum herstellen einer befüllten, sterilen spritzenvorrichtung
AT400304B (de) * 1994-02-28 1995-12-27 Immuno Ag Vorrichtung zur applikation eines mehrkomponenten-gewebeklebstoffes
US5578073A (en) * 1994-09-16 1996-11-26 Ramot Of Tel Aviv University Thromboresistant surface treatment for biomaterials
US5605541A (en) * 1994-12-07 1997-02-25 E. R. Squibb And Sons, Inc. Fibrin sealant applicatoor
DE69629010T2 (de) * 1995-01-16 2004-04-15 Baxter International Inc., Deerfield Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
US5580923A (en) * 1995-03-14 1996-12-03 Collagen Corporation Anti-adhesion films and compositions for medical use
CA2222426A1 (en) * 1995-06-06 1996-12-12 Andrew G. Hood, Iii Wound sealant preparation and application device and method
US5697903A (en) * 1996-02-22 1997-12-16 Ultradent Products, Inc. Methods and apparatus for dispensing compositions

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AU4536296A (en) 1996-08-07
US6074663A (en) 2000-06-13
ATE244584T1 (de) 2003-07-15
WO1996022115A1 (en) 1996-07-25
US5989215A (en) 1999-11-23
JPH11502431A (ja) 1999-03-02
AU697045B2 (en) 1998-09-24
EP0804257A1 (de) 1997-11-05
EP0804257B1 (de) 2003-07-09
DE69629010T2 (de) 2004-04-15
CA2207992A1 (en) 1996-07-25

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