DE69626041D1 - Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine - Google Patents
Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanineInfo
- Publication number
- DE69626041D1 DE69626041D1 DE69626041T DE69626041T DE69626041D1 DE 69626041 D1 DE69626041 D1 DE 69626041D1 DE 69626041 T DE69626041 T DE 69626041T DE 69626041 T DE69626041 T DE 69626041T DE 69626041 D1 DE69626041 D1 DE 69626041D1
- Authority
- DE
- Germany
- Prior art keywords
- sulfobenz
- indocyanine
- type
- fluorescence dyes
- dyes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Luminescent Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Detergent Compositions (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI002049A IT1276833B1 (it) | 1995-10-09 | 1995-10-09 | Coloranti fluorescenti della famiglia della solfo benz e indocianina |
PCT/EP1996/004377 WO1997013810A1 (en) | 1995-10-09 | 1996-10-08 | SULFO BENZ[e]INDOCYANINE FLUORESCENT DYES |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69626041D1 true DE69626041D1 (de) | 2003-03-06 |
Family
ID=11372321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69626041T Expired - Lifetime DE69626041D1 (de) | 1995-10-09 | 1996-10-08 | Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine |
Country Status (6)
Country | Link |
---|---|
US (1) | US6136612A (de) |
EP (1) | EP0876428B1 (de) |
AU (1) | AU706668B2 (de) |
DE (1) | DE69626041D1 (de) |
IT (1) | IT1276833B1 (de) |
WO (1) | WO1997013810A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6593148B1 (en) | 1994-03-01 | 2003-07-15 | Li-Cor, Inc. | Cyanine dye compounds and labeling methods |
DE19717904A1 (de) | 1997-04-23 | 1998-10-29 | Diagnostikforschung Inst | Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie |
KR100337169B1 (ko) | 1998-07-20 | 2002-05-18 | 최중갑 | 복합염료 조성물을 이용한 폴리머 겔상의 dna의 검출방법 및 |
US7547721B1 (en) | 1998-09-18 | 2009-06-16 | Bayer Schering Pharma Ag | Near infrared fluorescent contrast agent and fluorescence imaging |
JP2000095758A (ja) | 1998-09-18 | 2000-04-04 | Schering Ag | 近赤外蛍光造影剤および蛍光造影方法 |
US6605434B1 (en) | 1999-03-16 | 2003-08-12 | Human Genome Sciences, Inc. | Direct bacterial lysate sequencing |
DE19937024A1 (de) * | 1999-08-05 | 2001-02-08 | Bayer Ag | Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker |
WO2001050646A1 (en) * | 1999-12-30 | 2001-07-12 | Morphics Technology, Inc. | A configurable multimode despreader for spread spectrum applications |
US6716994B1 (en) | 2000-01-04 | 2004-04-06 | Applera Corporation | Mobility-Modifying Cyanine Dyes |
AU2001232818A1 (en) * | 2000-01-18 | 2001-07-31 | Mallinckrodt, Inc. | Hydrophilic cyanine dyes |
US7790144B2 (en) | 2000-01-18 | 2010-09-07 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
CA2424454C (en) * | 2000-09-19 | 2010-07-20 | Li-Cor, Inc. | Cyanine dyes |
US7597878B2 (en) * | 2000-09-19 | 2009-10-06 | Li-Cor, Inc. | Optical fluorescent imaging |
US6656451B1 (en) | 2000-10-16 | 2003-12-02 | Mallinckrodt, Inc. | Indole compounds as novel dyes for organ function monitoring |
US6335450B1 (en) * | 2000-11-09 | 2002-01-01 | Beckman Coulter, Inc. | Efficient cyclic-bridged cyanine dyes |
US6331632B1 (en) * | 2000-11-09 | 2001-12-18 | Beckman Coulter, Inc. | Cyanine dye phosphoramidites |
US6710363B1 (en) * | 2000-11-27 | 2004-03-23 | Uview Ultraviolet Systems, Inc. | Detection lamp equipped with light-emitting diode |
EP1209205A1 (de) | 2000-11-28 | 2002-05-29 | Innosense S.r.l. | Verbesserte Verfahren und Methode zur Herstellung von asymmetrischen monofunktionalisierten Indocyaninmarkern sowie erhaltene Verbindungen |
EP1211294B1 (de) * | 2000-11-28 | 2008-08-13 | Visen Medical, Inc. | Verbessertes Verfahren und Methode zur Herstellung von asymmetrischen monofunktionalisierten Indocyaninmarkern sowie erhaltene Verbindungen |
US6800438B2 (en) * | 2000-12-28 | 2004-10-05 | Xerox Corporation | Imager for DNA sequencer |
JP4319363B2 (ja) * | 2001-01-15 | 2009-08-26 | 富士フイルム株式会社 | ネガ型画像記録材料 |
WO2002068537A2 (en) | 2001-02-28 | 2002-09-06 | Stratagene | Fluorescent dye |
US20030124194A1 (en) * | 2002-01-02 | 2003-07-03 | Gaw Debra A. | Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor |
AU2003225763A1 (en) * | 2002-03-11 | 2003-09-29 | Visen Medical, Inc. | Optical imaging probes |
EP1539728A2 (de) * | 2002-07-01 | 2005-06-15 | Guava Technologies, Inc. | Fluoreszierende farbstoffe, energietransferpaare und verfahren |
US20040132092A1 (en) * | 2003-01-03 | 2004-07-08 | Stetson Christopher M. | Determining the density of functional moieties on polymer reagents |
WO2004108902A2 (en) * | 2003-06-04 | 2004-12-16 | Visen Medical, Inc. | Biocompatible fluorescent silicon nanoparticles |
ITPZ20030002A1 (it) * | 2003-08-12 | 2005-02-13 | Giuseppe Caputo | Composti del tipo cianina aventi un braccio di legame alchinilico |
US8227621B2 (en) | 2005-06-30 | 2012-07-24 | Li-Cor, Inc. | Cyanine dyes and methods of use |
AU2006284565B2 (en) | 2005-09-02 | 2013-05-30 | Visen Medical, Inc. | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels |
US7947256B2 (en) * | 2005-09-02 | 2011-05-24 | Visen Medical, Inc. | Biocompatible fluorescent imaging agents |
WO2007028118A2 (en) | 2005-09-02 | 2007-03-08 | Visen Medical, Inc. | Nicotinic acid and picolinic acid derived near-infrared fluorophores |
WO2007111669A2 (en) | 2005-12-22 | 2007-10-04 | Visen Medical, Inc. | Combined x-ray and optical tomographic imaging system |
WO2007136413A2 (en) | 2005-12-22 | 2007-11-29 | Visen Medical, Inc. | Biocompatible fluorescent metal oxide nanoparticles |
ITSV20060002A1 (it) * | 2006-01-19 | 2007-07-20 | Ferrania Technologies Spa | Colorante fluorescente di tipo cianinico |
JP4958461B2 (ja) * | 2006-03-30 | 2012-06-20 | 富士フイルム株式会社 | 近赤外吸収色素含有硬化性組成物 |
WO2008002236A1 (en) * | 2006-06-28 | 2008-01-03 | Ge Healthcare Bio-Sciences Ab | Method of detecting interactions between protein components |
DK2118206T3 (en) | 2007-02-09 | 2018-06-18 | Visen Medical Inc | POLYCYCLOF COLORS AND APPLICATION THEREOF |
WO2008109832A2 (en) * | 2007-03-08 | 2008-09-12 | Visen Medical, Inc. | Viable near-infrared fluorochrome labeled cells and methods of making and using same |
CN101743022A (zh) * | 2007-05-16 | 2010-06-16 | 通用电气医疗集团股份有限公司 | 光学成像剂 |
WO2009055095A1 (en) | 2007-10-19 | 2009-04-30 | Visen Medical, Inc. | Imaging systems featuring waveguiding compensation |
EP3320923B1 (de) | 2008-01-18 | 2022-04-06 | Visen Medical, Inc. | Fluoreszierende bildgebungsmittel |
CN102026671B (zh) | 2008-03-14 | 2014-09-03 | Visen医药公司 | 整联蛋白靶向试剂及使用其的体内和体外成像方法 |
US8864821B2 (en) * | 2008-11-26 | 2014-10-21 | Visen Medical, Inc. | Methods and compositions for identifying subjects at risk of developing stent thrombosis |
WO2010121163A2 (en) * | 2009-04-17 | 2010-10-21 | Li-Cor, Inc. | Fluorescent imaging with substituted cyanine dyes |
US20110021908A1 (en) * | 2009-05-27 | 2011-01-27 | Lumicell Diagnostics, Inc. | Methods and systems for spatially identifying abnormal cells |
US9155471B2 (en) | 2009-05-27 | 2015-10-13 | Lumicell, Inc'. | Methods and systems for spatially identifying abnormal cells |
US8401618B2 (en) * | 2009-08-28 | 2013-03-19 | Visen Medical, Inc. | Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique |
WO2011038006A1 (en) | 2009-09-22 | 2011-03-31 | Visen Medical, Inc. | Systems and methods for virtual index-matching of diffusive media |
EP2530093B1 (de) | 2010-01-28 | 2018-11-21 | National UniversityCorporation Mie University | Indocyaninverbindung, syntheseverfahren dafür, reinigungsverfahren dafür, diagnosezusammensetzung mit der indocyaninverbindung, vorrichtung zur messung von in-vivo-bewegungen sowie vorrichtung zur visualisierung von zirkulationen mithilfe der diagnosezusammensetzung |
JP5817073B2 (ja) * | 2010-01-28 | 2015-11-18 | 国立大学法人三重大学 | 新規インドシアニン化合物を用いた診断用組成物及び分析方法 |
DE102010022110A1 (de) * | 2010-05-31 | 2011-12-01 | LMU Universität München Department Chemie | Cyaninfarbstoffe als Kontrastmittel zur Unterstützung der Augenchirurgie |
WO2012054784A1 (en) | 2010-10-20 | 2012-04-26 | Li-Cor, Inc. | Fluorescent imaging with substituted cyanine dyes |
US9314304B2 (en) | 2010-12-08 | 2016-04-19 | Lumicell, Inc. | Methods and system for image guided cell ablation with microscopic resolution |
US10053447B2 (en) | 2010-12-21 | 2018-08-21 | Pierce Biotechnology, Inc | Fluorescent compounds |
WO2012154885A2 (en) | 2011-05-09 | 2012-11-15 | Visen Medical, Inc. | Carbonic anhydrase targeting agents and methods of using same |
US8889884B1 (en) | 2011-07-14 | 2014-11-18 | Pierce Biotechnology, Inc. | Phosphine derivatives of fluorescent compounds |
US9249307B2 (en) | 2011-08-16 | 2016-02-02 | Pierce Biotechnology, Inc. | Benzocyanine compounds |
US9751868B2 (en) | 2012-02-28 | 2017-09-05 | Pierce Biotechnology, Inc. | Benzocyanine compounds |
EP2804860B1 (de) | 2012-03-02 | 2016-06-15 | Pierce Biotechnology, Inc. | Indol-derivate als markierungsfarbstoff für biomoleküle |
CN114042171A (zh) | 2012-03-30 | 2022-02-15 | 文森医学公司 | 细菌成像剂及其使用方法 |
US9371362B2 (en) | 2012-08-15 | 2016-06-21 | Visen Medical, Inc. | Prostate specific antigen agents and methods of using same for prostate cancer imaging |
WO2014035712A1 (en) | 2012-08-28 | 2014-03-06 | Pierce Biotechnology, Inc. | Benzopyrylium compounds |
WO2014062716A1 (en) | 2012-10-15 | 2014-04-24 | Visen Medical, Inc. | Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources |
WO2014152389A1 (en) | 2013-03-14 | 2014-09-25 | Lumicell, Inc. | Imaging agent for detection of diseased cells |
CN105073761B (zh) | 2013-03-15 | 2020-10-20 | 文森医学公司 | 用于体外和体内成像和检测的取代的硅杂蒽阳离子红至近红外荧光染料 |
EP2970674B1 (de) | 2013-03-15 | 2018-12-12 | VisEn Medical, Inc. | 4,4-disubstituierte cyclohexyl-verbrückte heptamethin-cyanin-farbstoffe und verwendungen davon |
WO2015103420A1 (en) | 2013-12-31 | 2015-07-09 | Memorial Sloan Kettering Cancer Center | Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real time |
KR20170094268A (ko) | 2014-12-15 | 2017-08-17 | 메모리얼 슬로안-케터링 캔서 센터 | 향상된 신경-결합 선택성을 갖는 고리형 펩티드, 상기 고리형 펩티드와 결합된 나노입자, 및 실시간 생체내 신경 조직 영상화를 위한 이들의 용도 |
KR20180093961A (ko) | 2015-12-15 | 2018-08-22 | 메모리얼 슬로안-케터링 캔서 센터 | 조직 구별, 예를 들어, 수술 중 시각화를 위한 영상화 시스템 및 방법 |
BR112019010947A2 (pt) | 2016-11-30 | 2019-10-01 | Univ Cornell | nanopartículas ultrapequenas funcionalizadas por inibidores e métodos das mesmas |
KR101973456B1 (ko) * | 2017-10-17 | 2019-04-29 | 울산과학기술원 | 미토콘드리아에 표적화되는 수용성 화합물, 이를 포함하는 조성물 및 이의 제조방법 |
EP4015004A1 (de) | 2020-12-18 | 2022-06-22 | Phi Pharma SA | Proteoglykanspezifische verzweigte peptide |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5230781A (en) * | 1984-03-29 | 1993-07-27 | Li-Cor, Inc. | Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes |
US5268486A (en) * | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
JP2713976B2 (ja) * | 1987-04-24 | 1998-02-16 | イーストマン コダック カンパニー | 写真フィルター組成物 |
CA1337923C (en) * | 1988-07-07 | 1996-01-16 | Richard Lee Parton | Infrared filter dye for photographic element |
DE3912046B4 (de) * | 1988-09-02 | 2004-03-25 | Carnegie Mellon University | Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt |
WO1991000440A1 (en) * | 1989-07-04 | 1991-01-10 | Kabushiki Kaisha Kubota | Clutch operating device of vehicle |
JP2663033B2 (ja) * | 1990-02-22 | 1997-10-15 | 富士写真フイルム株式会社 | ハロゲン化銀乳剤 |
EP0626427B1 (de) * | 1993-05-26 | 2001-08-16 | Agfa-Gevaert N.V. | Im nahen Infrarot absorbierende Farbstoffe und diese enthaltende photographische Aufzeichnungselemente |
US5453505A (en) * | 1994-06-30 | 1995-09-26 | Biometric Imaging, Inc. | N-heteroaromatic ion and iminium ion substituted cyanine dyes for use as fluorescence labels |
-
1995
- 1995-10-09 IT IT95MI002049A patent/IT1276833B1/it active IP Right Grant
-
1996
- 1996-10-08 US US09/043,767 patent/US6136612A/en not_active Expired - Lifetime
- 1996-10-08 DE DE69626041T patent/DE69626041D1/de not_active Expired - Lifetime
- 1996-10-08 WO PCT/EP1996/004377 patent/WO1997013810A1/en active IP Right Grant
- 1996-10-08 AU AU72882/96A patent/AU706668B2/en not_active Expired
- 1996-10-08 EP EP96934591A patent/EP0876428B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ITMI952049A1 (it) | 1997-04-09 |
EP0876428B1 (de) | 2004-11-17 |
AU7288296A (en) | 1997-04-30 |
WO1997013810A1 (en) | 1997-04-17 |
AU706668B2 (en) | 1999-06-17 |
ITMI952049A0 (de) | 1995-10-09 |
US6136612A (en) | 2000-10-24 |
IT1276833B1 (it) | 1997-11-03 |
EP0876428A1 (de) | 1998-11-11 |
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