DE69621229D1 - Antivirale triazazyklododecane - Google Patents

Antivirale triazazyklododecane

Info

Publication number
DE69621229D1
DE69621229D1 DE69621229T DE69621229T DE69621229D1 DE 69621229 D1 DE69621229 D1 DE 69621229D1 DE 69621229 T DE69621229 T DE 69621229T DE 69621229 T DE69621229 T DE 69621229T DE 69621229 D1 DE69621229 D1 DE 69621229D1
Authority
DE
Germany
Prior art keywords
group
aromatic
independently
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621229T
Other languages
English (en)
Inventor
W Bell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Application granted granted Critical
Publication of DE69621229D1 publication Critical patent/DE69621229D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69621229T 1995-02-17 1996-02-16 Antivirale triazazyklododecane Expired - Lifetime DE69621229D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/392,550 US5663161A (en) 1995-02-17 1995-02-17 Anti-viral triaza compounds
PCT/US1996/002132 WO1996025167A1 (en) 1995-02-17 1996-02-16 Anti-viral triaza compounds

Publications (1)

Publication Number Publication Date
DE69621229D1 true DE69621229D1 (de) 2002-06-20

Family

ID=23551026

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621229T Expired - Lifetime DE69621229D1 (de) 1995-02-17 1996-02-16 Antivirale triazazyklododecane

Country Status (10)

Country Link
US (3) US5663161A (de)
EP (1) EP0809504B1 (de)
JP (1) JPH11500130A (de)
CN (1) CN1181013A (de)
AT (1) ATE217529T1 (de)
AU (1) AU701783B2 (de)
CA (1) CA2211920A1 (de)
DE (1) DE69621229D1 (de)
MX (1) MX9706259A (de)
WO (1) WO1996025167A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0841951A2 (de) * 1995-06-26 1998-05-20 Concat Ltd. Verbindungen mit chelatbildungs- und spezifizitätseigenschaften für elemente der ersten übergangsgruppe sowie deren verwendung in der medizinischen therapie und diagnostik
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US20050049242A1 (en) * 2000-12-21 2005-03-03 W. Edward Robinson Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors
WO2002080856A2 (en) * 2001-04-06 2002-10-17 University And Community College System Of Nevada On Behalf Of The University Of Nevada, Reno Triaza compound immunoregulatory agents
US6699465B2 (en) 2001-05-18 2004-03-02 Albany Medical College Covalent attachment of polymer to cell to prevent virus bonding to receptor
MXPA04010450A (es) * 2002-04-22 2005-09-08 Univ Maryland Inhibicion antiviral de la proteina del recubrimiento capsomerico.
WO2006019955A2 (en) * 2004-07-14 2006-02-23 President And Fellows Of Harvard College Antiviral methods and compositions
WO2009055010A2 (en) * 2007-10-25 2009-04-30 President And Fellows Of Harvard College Systems and methods for studying influenza
JP6421652B2 (ja) * 2015-03-06 2018-11-14 横浜ゴム株式会社 空気入りタイヤ
GB2539881B (en) * 2015-06-24 2018-07-25 Advanced Risc Mach Ltd An apparatus and method for processing floating point values
HUE062455T2 (hu) * 2018-03-16 2023-11-28 Kezar Life Sciences Triazaciklododekánszulfonamid ("TCD") alapú fehérjeszekréciós inhibitorok
EP3774850A1 (de) 2018-03-29 2021-02-17 Kezar Life Sciences Cdp-protein-sekretionsinhibitoren

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001212A (en) * 1973-10-03 1977-01-04 E. I. Du Pont De Nemours And Company Macrocyclic polyamines
US5316757A (en) * 1984-10-18 1994-05-31 Board Of Regents, The University Of Texas System Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies
GB8719041D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
US5021409A (en) * 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
WO1991010669A1 (en) * 1990-01-19 1991-07-25 Cockbain, Julian, Roderick, Michaelson Chelating compounds
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
JPH0827129A (ja) 1994-07-18 1996-01-30 Rikagaku Kenkyusho 環状ポリアミン化合物及びそれを有効成分とする抗ウィルス剤

Also Published As

Publication number Publication date
JPH11500130A (ja) 1999-01-06
EP0809504B1 (de) 2002-05-15
US6342492B1 (en) 2002-01-29
AU5170496A (en) 1996-09-04
EP0809504A4 (de) 1998-11-04
ATE217529T1 (de) 2002-06-15
CA2211920A1 (en) 1996-08-22
US20020019423A1 (en) 2002-02-14
AU701783B2 (en) 1999-02-04
CN1181013A (zh) 1998-05-06
MX9706259A (es) 1997-11-29
WO1996025167A1 (en) 1996-08-22
EP0809504A1 (de) 1997-12-03
US5663161A (en) 1997-09-02

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