ATE217529T1 - Antivirale triazazyklododecane - Google Patents
Antivirale triazazyklododecaneInfo
- Publication number
- ATE217529T1 ATE217529T1 AT96908473T AT96908473T ATE217529T1 AT E217529 T1 ATE217529 T1 AT E217529T1 AT 96908473 T AT96908473 T AT 96908473T AT 96908473 T AT96908473 T AT 96908473T AT E217529 T1 ATE217529 T1 AT E217529T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- aromatic
- independently
- formula
- alkyl
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/392,550 US5663161A (en) | 1995-02-17 | 1995-02-17 | Anti-viral triaza compounds |
| PCT/US1996/002132 WO1996025167A1 (en) | 1995-02-17 | 1996-02-16 | Anti-viral triaza compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE217529T1 true ATE217529T1 (de) | 2002-06-15 |
Family
ID=23551026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96908473T ATE217529T1 (de) | 1995-02-17 | 1996-02-16 | Antivirale triazazyklododecane |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US5663161A (de) |
| EP (1) | EP0809504B1 (de) |
| JP (1) | JPH11500130A (de) |
| CN (1) | CN1181013A (de) |
| AT (1) | ATE217529T1 (de) |
| AU (1) | AU701783B2 (de) |
| CA (1) | CA2211920A1 (de) |
| DE (1) | DE69621229D1 (de) |
| MX (1) | MX9706259A (de) |
| WO (1) | WO1996025167A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3356289B2 (ja) * | 1995-06-26 | 2002-12-16 | コンキャット リミティド | 第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその医療および診断への使用 |
| US6335339B1 (en) | 1998-01-13 | 2002-01-01 | Scriptgen Pharmaceuticals, Inc. | Triazine antiviral compounds |
| US20050049242A1 (en) * | 2000-12-21 | 2005-03-03 | W. Edward Robinson | Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors |
| WO2002080856A2 (en) * | 2001-04-06 | 2002-10-17 | University And Community College System Of Nevada On Behalf Of The University Of Nevada, Reno | Triaza compound immunoregulatory agents |
| US6699465B2 (en) | 2001-05-18 | 2004-03-02 | Albany Medical College | Covalent attachment of polymer to cell to prevent virus bonding to receptor |
| CA2483227A1 (en) * | 2002-04-22 | 2003-10-30 | University Of Maryland, Baltimore County | Antiviral inhibition of capsid proteins |
| WO2006019955A2 (en) * | 2004-07-14 | 2006-02-23 | President And Fellows Of Harvard College | Antiviral methods and compositions |
| WO2009055010A2 (en) * | 2007-10-25 | 2009-04-30 | President And Fellows Of Harvard College | Systems and methods for studying influenza |
| JP6421652B2 (ja) * | 2015-03-06 | 2018-11-14 | 横浜ゴム株式会社 | 空気入りタイヤ |
| GB2539881B (en) * | 2015-06-24 | 2018-07-25 | Advanced Risc Mach Ltd | An apparatus and method for processing floating point values |
| LT3765447T (lt) * | 2018-03-16 | 2023-08-10 | Kezar Life Sciences | Baltymų sekrecijos inhibitoriai triazaciklododekansulfonamido ("tcd") pagrindu |
| CA3095471A1 (en) | 2018-03-29 | 2019-10-03 | Kezar Life Sciences | Cdp protein secretion inhibitors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001212A (en) * | 1973-10-03 | 1977-01-04 | E. I. Du Pont De Nemours And Company | Macrocyclic polyamines |
| US5316757A (en) | 1984-10-18 | 1994-05-31 | Board Of Regents, The University Of Texas System | Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups |
| US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
| GB8719041D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| US5021409A (en) * | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| EP0511275A1 (de) * | 1990-01-19 | 1992-11-04 | Nycomed Imaging As | Komplexbildner |
| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| JPH0827129A (ja) * | 1994-07-18 | 1996-01-30 | Rikagaku Kenkyusho | 環状ポリアミン化合物及びそれを有効成分とする抗ウィルス剤 |
-
1995
- 1995-02-17 US US08/392,550 patent/US5663161A/en not_active Expired - Fee Related
-
1996
- 1996-02-16 DE DE69621229T patent/DE69621229D1/de not_active Expired - Lifetime
- 1996-02-16 AT AT96908473T patent/ATE217529T1/de not_active IP Right Cessation
- 1996-02-16 MX MX9706259A patent/MX9706259A/es not_active IP Right Cessation
- 1996-02-16 WO PCT/US1996/002132 patent/WO1996025167A1/en not_active Ceased
- 1996-02-16 US US08/894,491 patent/US6342492B1/en not_active Expired - Fee Related
- 1996-02-16 EP EP96908473A patent/EP0809504B1/de not_active Expired - Lifetime
- 1996-02-16 AU AU51704/96A patent/AU701783B2/en not_active Ceased
- 1996-02-16 CN CN96193110A patent/CN1181013A/zh active Pending
- 1996-02-16 JP JP8525169A patent/JPH11500130A/ja active Pending
- 1996-02-16 CA CA002211920A patent/CA2211920A1/en not_active Abandoned
-
2001
- 2001-01-25 US US09/769,021 patent/US20020019423A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11500130A (ja) | 1999-01-06 |
| EP0809504A1 (de) | 1997-12-03 |
| US6342492B1 (en) | 2002-01-29 |
| EP0809504A4 (de) | 1998-11-04 |
| WO1996025167A1 (en) | 1996-08-22 |
| MX9706259A (es) | 1997-11-29 |
| CN1181013A (zh) | 1998-05-06 |
| US5663161A (en) | 1997-09-02 |
| DE69621229D1 (de) | 2002-06-20 |
| US20020019423A1 (en) | 2002-02-14 |
| EP0809504B1 (de) | 2002-05-15 |
| AU701783B2 (en) | 1999-02-04 |
| CA2211920A1 (en) | 1996-08-22 |
| AU5170496A (en) | 1996-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |