DE69534354D1 - CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE - Google Patents

CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE

Info

Publication number
DE69534354D1
DE69534354D1 DE69534354T DE69534354T DE69534354D1 DE 69534354 D1 DE69534354 D1 DE 69534354D1 DE 69534354 T DE69534354 T DE 69534354T DE 69534354 T DE69534354 T DE 69534354T DE 69534354 D1 DE69534354 D1 DE 69534354D1
Authority
DE
Germany
Prior art keywords
bursal disease
infectious bursal
ibdv
strains
chimerial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69534354T
Other languages
English (en)
Other versions
DE69534354T2 (de
Inventor
Vikram Vakharia
David B Snyder
Stephanie A Mengel-Whersat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland at Baltimore
Original Assignee
University of Maryland at Baltimore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland at Baltimore filed Critical University of Maryland at Baltimore
Application granted granted Critical
Publication of DE69534354D1 publication Critical patent/DE69534354D1/de
Publication of DE69534354T2 publication Critical patent/DE69534354T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/10011Birnaviridae
    • C12N2720/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69534354T 1994-03-29 1995-03-29 CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE Expired - Fee Related DE69534354T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US219262 1994-03-29
US08/219,262 US5788970A (en) 1994-03-29 1994-03-29 Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon
PCT/US1995/003772 WO1995026196A1 (en) 1994-03-29 1995-03-29 CHIMERIC INFECTIOUS BURSAL DISEASE VIRUS cDNA CLONES, EXPRESSION PRODUCTS AND VACCINES BASED THEREON

Publications (2)

Publication Number Publication Date
DE69534354D1 true DE69534354D1 (de) 2005-09-08
DE69534354T2 DE69534354T2 (de) 2006-03-23

Family

ID=22818561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534354T Expired - Fee Related DE69534354T2 (de) 1994-03-29 1995-03-29 CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE

Country Status (10)

Country Link
US (3) US5788970A (de)
EP (1) EP0755259B1 (de)
JP (2) JPH09510873A (de)
AT (1) ATE300950T1 (de)
AU (1) AU696656B2 (de)
CA (1) CA2186856A1 (de)
DE (1) DE69534354T2 (de)
DK (1) DK0755259T3 (de)
ES (1) ES2249769T3 (de)
WO (1) WO1995026196A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871744A (en) * 1996-09-05 1999-02-16 University Of Maryland-Biotechnology Inst. Method for generating birnavirus from synthetic RNA transcripts
EP0887412B1 (de) * 1997-05-26 2003-10-15 Akzo Nobel N.V. Rekombinanter Birnavirusimpfstoff
CA2238659C (en) 1997-05-26 2010-12-14 Akzo Nobel N.V. Recombinant birnavirus vaccine
US6231868B1 (en) 1997-09-30 2001-05-15 University Of Maryland-Biotechnology Institute Method for generating nonpathogenic infections birnavirus from synthetic RNA transcripts
WO1999050419A2 (en) * 1998-03-31 1999-10-07 University Of Maryland Biotechnology Institute A method for generating nonpathogenic, infectious pancreatic necrosis virus (ipnv) from synthetic rna transcripts
WO2000012677A2 (en) * 1998-09-01 2000-03-09 The University Of Hong Kong Generation of recombinant infectious bursal disease viruses by reverse genetics technology and the use of the recombinant viruses as attenuated vaccines
US6492148B1 (en) * 1999-03-05 2002-12-10 Akzo Nobel Nv Genetically engineered cell culture adapted infectious bursal disease virus (IBDV) mutants
US6468984B1 (en) 1999-06-08 2002-10-22 Innovo Biotechnologies Ltd. DNA vaccine for protecting an avian against infectious bursal disease virus
EP1069187A1 (de) * 1999-07-14 2001-01-17 Stichting Dienst Landbouwkundig Onderzoek Mosaik-Virus der infectiösen Bursal-Krankheit enthaltender Impfstoff
AU2001266025A1 (en) * 2000-05-31 2001-12-11 Akzo Nobel N.V. Serotype chimeric ibdv strains
WO2001097839A1 (en) * 2000-06-19 2001-12-27 Rahan Meristem Recombinant vaccines against infectious bursal disease virus
US6485940B2 (en) 2000-07-07 2002-11-26 Akzo Nobel N.V. Broad spectrum infectious bursal disease virus vaccine
EP1170302B1 (de) * 2000-07-07 2006-06-21 Intervet International BV Impfstoffe basierend auf Mutanten des Virus der infektiösen Bursal-Krankheit
WO2002038753A1 (fr) * 2000-11-09 2002-05-16 Junichi Watanabe Procede de criblage d'un gene agissant sur les conditions pathologiques ou la survie d'un animal infecte par un pathogene
CA2457349A1 (en) * 2001-08-10 2003-02-20 University Of Maryland Biotechnology Institute Sub-unit vaccine for infectious pancreatic necrosis virus
US7431930B2 (en) 2002-03-01 2008-10-07 Intervet International B.V. Infectious bursal disease virus (IBDV) mutant expressing virus neutralising epitopes specific for classic-and variant IBDV strains
AU2003227026A1 (en) * 2002-03-01 2003-09-16 Akzo Nobel N.V. An infectious bursal disease virus variant
RU2340672C2 (ru) * 2003-03-24 2008-12-10 Интервет Интернэшнл Б.В. Мутант вируса инфекционной бурсальной болезни (ibdv), экспрессирующий вирус-нейтрализующие эпитопы, специфичные для классического и вариантного штаммов ibdv
ES2217967B1 (es) * 2003-03-31 2006-01-01 Consejo Sup. Investig. Cientificas Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv.
ES2307346B1 (es) * 2004-01-21 2009-11-13 Consejo Sup. Investig. Cientificas Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
ES2307345B1 (es) * 2004-01-21 2009-11-13 Consejo Sup. Investig. Cientificas Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
CN1930284B (zh) * 2004-03-12 2010-06-23 惠氏公司 传染性囊病病毒抗原分离株和疫苗
US7244432B2 (en) * 2004-12-08 2007-07-17 University Of Maryland Biotechnology Institute Infectious bursal disease virus (IBDV) variant from Georgia
US7491399B2 (en) 2005-06-23 2009-02-17 University Of Maryland Biotechnology Institute In Ovo vaccine against infectious bursal disease
ES2310062B1 (es) * 2005-07-15 2009-11-13 Bionostra, S.L. Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones.
WO2007020017A1 (en) * 2005-08-12 2007-02-22 Bionostra, S.L. Composition for bird immunization administered by aerosol
SG10202012986SA (en) 2006-09-29 2021-01-28 Ligocyte Pharmaceuticals Inc Norovirus vaccine formulations
US20100266636A1 (en) 2007-09-18 2010-10-21 Ligocyte Pharmaceuticals, Inc. Method of conferring a protective immune response to norovirus
SG184733A1 (en) 2007-09-18 2012-10-30 Ligocyte Pharmaceuticals Inc Method of conferring a protective immune response to norovirus
WO2009135518A1 (en) * 2008-05-09 2009-11-12 Chimera Pharma S.L.U. Chimeric fusion proteins and virus like particles from birnavirus vp2
CN102177233B (zh) * 2008-08-08 2015-04-15 莱戈赛特医药股份有限公司 用于增强交叉反应性的包含复合衣壳氨基酸序列的病毒样颗粒
EP2505640A1 (de) 2011-03-29 2012-10-03 Neo Virnatech, S.L. Impfstoffzusammensetzungen für vom Birnavirus übertragenen Krankheiten
CN105031637A (zh) 2011-07-11 2015-11-11 武田疫苗股份有限公司 胃肠外诺如病毒疫苗配制剂
CN112159480B (zh) * 2020-10-15 2022-03-22 福建农林大学 一种鸡传染性法氏囊病病毒多抗原表位蛋白及其应用
CN112409454B (zh) * 2020-11-04 2022-07-05 青岛农业大学 一种法氏囊七肽及其制备方法和应用
CN112375125B (zh) * 2020-11-23 2021-09-28 东北农业大学 一种多肽及其在预防鸡传染性法氏囊病中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908305A (en) * 1987-06-14 1990-03-13 The University Of Maryland Competitive elisa for determination of neutralizing IBDV antibody
WO1990015140A1 (en) * 1989-05-30 1990-12-13 Commonwealth Scientific And Industrial Research Organisation Production of ibdv vp2 in highly immunogenic form
WO1991016925A1 (en) * 1990-05-04 1991-11-14 University Of Maryland At College Park Specific dna sequences related to an ibdv protein including vectors, hosts and vaccines
US5595912A (en) * 1990-05-04 1997-01-21 University Of Maryland College Park Specific DNA and RNA sequences associated with US IBDV variants, vector carrying DNA sequences, host carrying cloned vector, deduced amino acid sequences, vaccine and method of vaccination

Also Published As

Publication number Publication date
AU696656B2 (en) 1998-09-17
WO1995026196A1 (en) 1995-10-05
JP2005200420A (ja) 2005-07-28
US5788970A (en) 1998-08-04
AU2129195A (en) 1995-10-17
DE69534354T2 (de) 2006-03-23
CA2186856A1 (en) 1995-10-05
US6017759A (en) 2000-01-25
EP0755259A1 (de) 1997-01-29
DK0755259T3 (da) 2005-11-28
ES2249769T3 (es) 2006-04-01
EP0755259A4 (de) 1999-12-22
JPH09510873A (ja) 1997-11-04
EP0755259B1 (de) 2005-08-03
US6156314A (en) 2000-12-05
ATE300950T1 (de) 2005-08-15

Similar Documents

Publication Publication Date Title
DE69534354D1 (de) CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE
Zanetti et al. The immunology of new generation vaccines
CN100534529C (zh) 抗原的有序分子呈递,制备及使用的方法
DK0584348T3 (da) Genetisk vaccine mod immundefektvirusser
NO20050894L (no) Vaksinesammensetninger inneholdende beta-l-6-antigenmatriser
EP2425848A3 (de) Influenza-Immunogen und Impfstoff
PT91881A (pt) Processo para a preparacao de novas proteinas e peptideos de hiv uteis no diagnostico, profilaxia ou terapia da sida
LU91324I2 (fr) Vaccin papillomavirus humain Ätypes 6,11,16,18Ü(recombinant, adsorbé)-gardasil/silgard
Wang et al. Virus-like particles of hepatitis B virus core protein containing five mimotopes of infectious bursal disease virus (IBDV) protect chickens against IBDV
EP0232798A3 (de) Pseudorabies-Virus-Mutanten, diese enthaltende Vakzine, Verfahren zu deren Herstellung sowie Methoden für deren Anwendung
NZ232505A (en) Conjugate comprising hepatitis b core antigen (hbcag) particles coupled to a polypeptide with an antigenic epitope
NO904538D0 (no) Kimaere glykoproteiner inneholdende immunogene segmenter av humant parainfluensavirus type 3.
Arnon Synthetic peptides as the basis for future vaccines
WO1998046725A3 (en) Attenuated, invasive vaccines against fish pathogens
Chua et al. Opinion: making inactivated and subunit-based vaccines work
Francis Peptide vaccines for viral diseases
US4946676A (en) Vaccine comprising an immunogenic protein and, as an adjuvant, a substantially non-immunogenic, sequentially homologous peptide
CY1105176T1 (el) Χιμαιρικα νουκλεϊνικα οξεα και πολυπεπτιδια του ιου της λυσσας
Alexandrenne et al. Generating antibodies against the native form of the human prion protein (hPrP) in wild-type animals: a comparison between DNA and protein immunizations
MX2022007217A (es) Vacuna epitópica para virus de fiebre porcina africana.
DE3064590D1 (en) Process for the preparation of influenza a virus vaccinating strains, vaccinating strain and vaccine containing it
Winton Molecular approaches to fish vaccines
KR930012826A (ko) 변형된 소의 헤르페스바이러스 타입 1에 기초한 백신
Michel DNA-mediated immunization: prospects for hepatitis B vaccination
Gerin et al. Recombinant DNA and synthetic peptide approaches to HBV vaccine development: Immunogenicity and protective efficacy in chimpanzees.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee