DE69534354D1 - CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE - Google Patents
CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFEInfo
- Publication number
- DE69534354D1 DE69534354D1 DE69534354T DE69534354T DE69534354D1 DE 69534354 D1 DE69534354 D1 DE 69534354D1 DE 69534354 T DE69534354 T DE 69534354T DE 69534354 T DE69534354 T DE 69534354T DE 69534354 D1 DE69534354 D1 DE 69534354D1
- Authority
- DE
- Germany
- Prior art keywords
- bursal disease
- infectious bursal
- ibdv
- strains
- chimerial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000002299 complementary DNA Substances 0.000 title abstract 3
- 208000027312 Bursal disease Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000002458 infectious effect Effects 0.000 title 1
- 241000702626 Infectious bursal disease virus Species 0.000 abstract 5
- 230000002068 genetic effect Effects 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 231100000518 lethal Toxicity 0.000 abstract 2
- 230000001665 lethal effect Effects 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US219262 | 1994-03-29 | ||
US08/219,262 US5788970A (en) | 1994-03-29 | 1994-03-29 | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
PCT/US1995/003772 WO1995026196A1 (en) | 1994-03-29 | 1995-03-29 | CHIMERIC INFECTIOUS BURSAL DISEASE VIRUS cDNA CLONES, EXPRESSION PRODUCTS AND VACCINES BASED THEREON |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69534354D1 true DE69534354D1 (de) | 2005-09-08 |
DE69534354T2 DE69534354T2 (de) | 2006-03-23 |
Family
ID=22818561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69534354T Expired - Fee Related DE69534354T2 (de) | 1994-03-29 | 1995-03-29 | CHIMÄRE cDNA-KLONE DES VIRUS DER INFEKTIÖSEN BURSAL-KRANKHEIT, EXPRESSIONSPRODUKTE UND DARAUF BASIERENDE IMPFSTOFFE |
Country Status (10)
Country | Link |
---|---|
US (3) | US5788970A (de) |
EP (1) | EP0755259B1 (de) |
JP (2) | JPH09510873A (de) |
AT (1) | ATE300950T1 (de) |
AU (1) | AU696656B2 (de) |
CA (1) | CA2186856A1 (de) |
DE (1) | DE69534354T2 (de) |
DK (1) | DK0755259T3 (de) |
ES (1) | ES2249769T3 (de) |
WO (1) | WO1995026196A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5871744A (en) * | 1996-09-05 | 1999-02-16 | University Of Maryland-Biotechnology Inst. | Method for generating birnavirus from synthetic RNA transcripts |
EP0887412B1 (de) * | 1997-05-26 | 2003-10-15 | Akzo Nobel N.V. | Rekombinanter Birnavirusimpfstoff |
CA2238659C (en) | 1997-05-26 | 2010-12-14 | Akzo Nobel N.V. | Recombinant birnavirus vaccine |
US6231868B1 (en) | 1997-09-30 | 2001-05-15 | University Of Maryland-Biotechnology Institute | Method for generating nonpathogenic infections birnavirus from synthetic RNA transcripts |
WO1999050419A2 (en) * | 1998-03-31 | 1999-10-07 | University Of Maryland Biotechnology Institute | A method for generating nonpathogenic, infectious pancreatic necrosis virus (ipnv) from synthetic rna transcripts |
WO2000012677A2 (en) * | 1998-09-01 | 2000-03-09 | The University Of Hong Kong | Generation of recombinant infectious bursal disease viruses by reverse genetics technology and the use of the recombinant viruses as attenuated vaccines |
US6492148B1 (en) * | 1999-03-05 | 2002-12-10 | Akzo Nobel Nv | Genetically engineered cell culture adapted infectious bursal disease virus (IBDV) mutants |
US6468984B1 (en) | 1999-06-08 | 2002-10-22 | Innovo Biotechnologies Ltd. | DNA vaccine for protecting an avian against infectious bursal disease virus |
EP1069187A1 (de) * | 1999-07-14 | 2001-01-17 | Stichting Dienst Landbouwkundig Onderzoek | Mosaik-Virus der infectiösen Bursal-Krankheit enthaltender Impfstoff |
AU2001266025A1 (en) * | 2000-05-31 | 2001-12-11 | Akzo Nobel N.V. | Serotype chimeric ibdv strains |
WO2001097839A1 (en) * | 2000-06-19 | 2001-12-27 | Rahan Meristem | Recombinant vaccines against infectious bursal disease virus |
US6485940B2 (en) | 2000-07-07 | 2002-11-26 | Akzo Nobel N.V. | Broad spectrum infectious bursal disease virus vaccine |
EP1170302B1 (de) * | 2000-07-07 | 2006-06-21 | Intervet International BV | Impfstoffe basierend auf Mutanten des Virus der infektiösen Bursal-Krankheit |
WO2002038753A1 (fr) * | 2000-11-09 | 2002-05-16 | Junichi Watanabe | Procede de criblage d'un gene agissant sur les conditions pathologiques ou la survie d'un animal infecte par un pathogene |
CA2457349A1 (en) * | 2001-08-10 | 2003-02-20 | University Of Maryland Biotechnology Institute | Sub-unit vaccine for infectious pancreatic necrosis virus |
US7431930B2 (en) | 2002-03-01 | 2008-10-07 | Intervet International B.V. | Infectious bursal disease virus (IBDV) mutant expressing virus neutralising epitopes specific for classic-and variant IBDV strains |
AU2003227026A1 (en) * | 2002-03-01 | 2003-09-16 | Akzo Nobel N.V. | An infectious bursal disease virus variant |
RU2340672C2 (ru) * | 2003-03-24 | 2008-12-10 | Интервет Интернэшнл Б.В. | Мутант вируса инфекционной бурсальной болезни (ibdv), экспрессирующий вирус-нейтрализующие эпитопы, специфичные для классического и вариантного штаммов ibdv |
ES2217967B1 (es) * | 2003-03-31 | 2006-01-01 | Consejo Sup. Investig. Cientificas | Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv. |
ES2307346B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
ES2307345B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
CN1930284B (zh) * | 2004-03-12 | 2010-06-23 | 惠氏公司 | 传染性囊病病毒抗原分离株和疫苗 |
US7244432B2 (en) * | 2004-12-08 | 2007-07-17 | University Of Maryland Biotechnology Institute | Infectious bursal disease virus (IBDV) variant from Georgia |
US7491399B2 (en) | 2005-06-23 | 2009-02-17 | University Of Maryland Biotechnology Institute | In Ovo vaccine against infectious bursal disease |
ES2310062B1 (es) * | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
WO2007020017A1 (en) * | 2005-08-12 | 2007-02-22 | Bionostra, S.L. | Composition for bird immunization administered by aerosol |
SG10202012986SA (en) | 2006-09-29 | 2021-01-28 | Ligocyte Pharmaceuticals Inc | Norovirus vaccine formulations |
US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
SG184733A1 (en) | 2007-09-18 | 2012-10-30 | Ligocyte Pharmaceuticals Inc | Method of conferring a protective immune response to norovirus |
WO2009135518A1 (en) * | 2008-05-09 | 2009-11-12 | Chimera Pharma S.L.U. | Chimeric fusion proteins and virus like particles from birnavirus vp2 |
CN102177233B (zh) * | 2008-08-08 | 2015-04-15 | 莱戈赛特医药股份有限公司 | 用于增强交叉反应性的包含复合衣壳氨基酸序列的病毒样颗粒 |
EP2505640A1 (de) | 2011-03-29 | 2012-10-03 | Neo Virnatech, S.L. | Impfstoffzusammensetzungen für vom Birnavirus übertragenen Krankheiten |
CN105031637A (zh) | 2011-07-11 | 2015-11-11 | 武田疫苗股份有限公司 | 胃肠外诺如病毒疫苗配制剂 |
CN112159480B (zh) * | 2020-10-15 | 2022-03-22 | 福建农林大学 | 一种鸡传染性法氏囊病病毒多抗原表位蛋白及其应用 |
CN112409454B (zh) * | 2020-11-04 | 2022-07-05 | 青岛农业大学 | 一种法氏囊七肽及其制备方法和应用 |
CN112375125B (zh) * | 2020-11-23 | 2021-09-28 | 东北农业大学 | 一种多肽及其在预防鸡传染性法氏囊病中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4908305A (en) * | 1987-06-14 | 1990-03-13 | The University Of Maryland | Competitive elisa for determination of neutralizing IBDV antibody |
WO1990015140A1 (en) * | 1989-05-30 | 1990-12-13 | Commonwealth Scientific And Industrial Research Organisation | Production of ibdv vp2 in highly immunogenic form |
WO1991016925A1 (en) * | 1990-05-04 | 1991-11-14 | University Of Maryland At College Park | Specific dna sequences related to an ibdv protein including vectors, hosts and vaccines |
US5595912A (en) * | 1990-05-04 | 1997-01-21 | University Of Maryland College Park | Specific DNA and RNA sequences associated with US IBDV variants, vector carrying DNA sequences, host carrying cloned vector, deduced amino acid sequences, vaccine and method of vaccination |
-
1994
- 1994-03-29 US US08/219,262 patent/US5788970A/en not_active Expired - Fee Related
-
1995
- 1995-03-29 AT AT95914198T patent/ATE300950T1/de not_active IP Right Cessation
- 1995-03-29 EP EP95914198A patent/EP0755259B1/de not_active Expired - Lifetime
- 1995-03-29 WO PCT/US1995/003772 patent/WO1995026196A1/en active IP Right Grant
- 1995-03-29 DE DE69534354T patent/DE69534354T2/de not_active Expired - Fee Related
- 1995-03-29 AU AU21291/95A patent/AU696656B2/en not_active Ceased
- 1995-03-29 ES ES95914198T patent/ES2249769T3/es not_active Expired - Lifetime
- 1995-03-29 JP JP7525247A patent/JPH09510873A/ja active Pending
- 1995-03-29 DK DK95914198T patent/DK0755259T3/da active
- 1995-03-29 CA CA002186856A patent/CA2186856A1/en not_active Abandoned
-
1998
- 1998-02-27 US US09/031,655 patent/US6017759A/en not_active Expired - Fee Related
-
1999
- 1999-06-15 US US09/332,978 patent/US6156314A/en not_active Expired - Fee Related
-
2005
- 2005-01-28 JP JP2005020679A patent/JP2005200420A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU696656B2 (en) | 1998-09-17 |
WO1995026196A1 (en) | 1995-10-05 |
JP2005200420A (ja) | 2005-07-28 |
US5788970A (en) | 1998-08-04 |
AU2129195A (en) | 1995-10-17 |
DE69534354T2 (de) | 2006-03-23 |
CA2186856A1 (en) | 1995-10-05 |
US6017759A (en) | 2000-01-25 |
EP0755259A1 (de) | 1997-01-29 |
DK0755259T3 (da) | 2005-11-28 |
ES2249769T3 (es) | 2006-04-01 |
EP0755259A4 (de) | 1999-12-22 |
JPH09510873A (ja) | 1997-11-04 |
EP0755259B1 (de) | 2005-08-03 |
US6156314A (en) | 2000-12-05 |
ATE300950T1 (de) | 2005-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |