DE69533404D1 - Diferentiell bioabbaubare medizinische inplantate - Google Patents

Diferentiell bioabbaubare medizinische inplantate

Info

Publication number
DE69533404D1
DE69533404D1 DE69533404T DE69533404T DE69533404D1 DE 69533404 D1 DE69533404 D1 DE 69533404D1 DE 69533404 T DE69533404 T DE 69533404T DE 69533404 T DE69533404 T DE 69533404T DE 69533404 D1 DE69533404 D1 DE 69533404D1
Authority
DE
Germany
Prior art keywords
implant
bioabbaubable
inplants
differentially
medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533404T
Other languages
English (en)
Other versions
DE69533404T3 (de
DE69533404T2 (de
Inventor
H Sierra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Surgical Specialties US Corp
Original Assignee
Cohesion Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22243067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69533404(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cohesion Technologies Inc filed Critical Cohesion Technologies Inc
Application granted granted Critical
Publication of DE69533404D1 publication Critical patent/DE69533404D1/de
Publication of DE69533404T2 publication Critical patent/DE69533404T2/de
Publication of DE69533404T3 publication Critical patent/DE69533404T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0036—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Dental Prosthetics (AREA)
DE69533404T 1994-10-03 1995-10-03 Diferentiell bioabbaubare medizinische inplantate Expired - Lifetime DE69533404T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOPCT/US94/11209 1994-10-03
PCT/US1994/011209 WO1996010374A1 (en) 1994-10-03 1994-10-03 Differentially biodegradable biomedical implants
PCT/US1995/012802 WO1996010428A1 (en) 1994-10-03 1995-10-03 Differentially biodegradable biomedical implants

Publications (3)

Publication Number Publication Date
DE69533404D1 true DE69533404D1 (de) 2004-09-23
DE69533404T2 DE69533404T2 (de) 2005-09-08
DE69533404T3 DE69533404T3 (de) 2011-03-10

Family

ID=22243067

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533404T Expired - Lifetime DE69533404T3 (de) 1994-10-03 1995-10-03 Diferentiell bioabbaubare medizinische inplantate

Country Status (7)

Country Link
EP (1) EP0784490B2 (de)
JP (2) JPH10506811A (de)
AT (1) ATE273721T1 (de)
AU (2) AU1287895A (de)
CA (1) CA2201526C (de)
DE (1) DE69533404T3 (de)
WO (2) WO1996010374A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916585A (en) * 1996-06-03 1999-06-29 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto biodegradable polymers
US7320962B2 (en) 1996-08-27 2008-01-22 Baxter International Inc. Hemoactive compositions and methods for their manufacture and use
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
DE19812195C2 (de) * 1998-03-19 2000-03-30 Uwe Storch Verfahren zur Herstellung eines gewebebildenden Implantats und seine Verwendung
US6224630B1 (en) 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
EP1259168B1 (de) 2000-02-24 2010-09-08 Loma Linda University Medical Center Pflaster und abgabesystem von kleber zum schliessen einer gewebeöffnung während einer chirurgischen behandlung
US6582713B2 (en) * 2000-04-06 2003-06-24 Univ. Of Colorado - Colorado Springs Compositions and methods for promoting wound healing
US6890342B2 (en) 2000-08-02 2005-05-10 Loma Linda University Method and apparatus for closing vascular puncture using hemostatic material
FR2816847B1 (fr) * 2000-11-22 2006-07-14 Assist Publ Hopitaux De Paris Biomateriaux polymeriques poreux, procede de preparation et utilisations
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7066934B2 (en) 2001-07-19 2006-06-27 Loma Linda University Adhesive including medicament and device and method for applying same
US20030044380A1 (en) * 2001-07-19 2003-03-06 Zhu Yong Hua Adhesive including medicament
US7223289B2 (en) 2002-04-16 2007-05-29 Warsaw Orthopedic, Inc. Annulus repair systems and techniques
GB2393655B (en) * 2002-09-27 2005-08-24 Johnson & Johnson Medical Ltd Wound treatment device
WO2004084963A1 (en) * 2003-03-25 2004-10-07 Smith & Nephew, Plc Porous medical adhesive comprising cyanonacrylate
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US8187627B2 (en) 2003-09-05 2012-05-29 Loma Linda University Medical Center Dressing delivery system for internal wounds
EP1604693A1 (de) * 2004-06-09 2005-12-14 Scil Technology GmbH In-situ hergestelltes Gerüst, dessen Herstellungsverfahren und dessen Verwendung
US8535702B2 (en) 2005-02-01 2013-09-17 Boston Scientific Scimed, Inc. Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
JP5253170B2 (ja) 2005-10-05 2013-07-31 ローマ リンダ ユニヴァーシティ メディカル センター 血管創の閉鎖装置および方法
DE102006033167A1 (de) 2006-07-10 2008-01-24 Gelita Ag Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung eines vernetzenden medizinischen Klebers
DE102006033168A1 (de) 2006-07-10 2008-01-17 Gelita Ag Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung einer vernetzenden therapeutischen Zusammensetzung
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー／エス 止血および／または創傷治癒を促進するための装置
US8173722B2 (en) 2008-07-10 2012-05-08 Aesculap Ag Adhesive compositions for use in surgical therapy
DE102008033378A1 (de) 2008-07-10 2010-01-14 Aesculap Ag Klebstoffzusammensetzung, insbesondere zur Verwendung in der chirurgischen Medizin
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
AU2010262058B2 (en) 2009-06-16 2013-08-29 Baxter Healthcare S.A. Hemostatic sponge
JP2013514093A (ja) 2009-12-16 2013-04-25 バクスター・インターナショナル・インコーポレイテッド 止血スポンジ
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
MX344402B (es) 2010-06-01 2016-12-14 Baxter Int Inc * Proceso para elaborar composiciones hemostaticas secas y estables.
ES2682302T3 (es) 2010-06-01 2018-09-19 Baxter International Inc Proceso para la producción de composiciones hemostáticas secas y estables
WO2011151386A1 (en) 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
US8440618B2 (en) 2011-01-19 2013-05-14 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Composition for the attachment of implants to collagen or other components of biological tissue
TWI449546B (zh) * 2011-09-07 2014-08-21 Ind Tech Res Inst 應用於軟硬組織修復與再生之生醫材料
MX356185B (es) 2011-10-11 2018-05-17 Baxter Int Composiciones hemostaticas.
EP2766058B1 (de) 2011-10-11 2022-11-23 Baxter International Inc. Hämostatische zusammensetzungen
CN103889447B (zh) 2011-10-27 2015-11-25 巴克斯特国际公司 止血组合物
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
CA2874290C (en) 2012-06-12 2020-02-25 Ferrosan Medical Devices A/S Dry haemostatic composition
US20140186441A1 (en) * 2012-12-28 2014-07-03 DePuy Synthes Products, LLC Composites for Osteosynthesis
WO2014202760A2 (en) 2013-06-21 2014-12-24 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
EP3079731B1 (de) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Trockenzusammensetzung mit extrusionsverstärker
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
FR3031742B1 (fr) 2015-01-21 2016-12-23 Ab7 Innovation Procede d'elaboration d'un materiau composite non poreux hydro- et/ou lipo-absorbant de compositions actives liquides
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
EP3165240A1 (de) * 2015-11-05 2017-05-10 Ecole Polytechnique Federale De Lausanne (Epfl) Von natürlichen polymeren abgeleitetes gerüstmaterial und verfahren zur herstellung davon
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
CN111888524A (zh) * 2020-08-04 2020-11-06 宁波迪创医疗科技有限公司 一种组织填充材料及其制备方法、组织工程支架和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905878A1 (de) 1979-02-16 1980-08-28 Merck Patent Gmbh Implantationsmaterialien und verfahren zu ihrer herstellung
EP0192068B1 (de) * 1985-02-19 1990-05-23 The Dow Chemical Company Hartgewebeprothese und Verfahren zu ihrer Herstellung
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
US4843112A (en) 1987-03-12 1989-06-27 The Beth Israel Hospital Association Bioerodable implant composition
US4849285A (en) 1987-06-01 1989-07-18 Bio Med Sciences, Inc. Composite macrostructure of ceramic and organic biomaterials
US4898734A (en) 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US4863974A (en) 1988-08-03 1989-09-05 W. L. Gore & Associates, Inc. Bone growth matrix and process for making it
IL90690A0 (en) * 1988-09-30 1990-01-18 Organogenesis Inc Tissue equivalents and their preparation
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5077049A (en) 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5141522A (en) 1990-02-06 1992-08-25 American Cyanamid Company Composite material having absorbable and non-absorbable components for use with mammalian tissue
US5098779A (en) 1990-06-25 1992-03-24 W. L. Gore & Associates, Inc. Carvable implant material
EP0560014A1 (de) 1992-03-12 1993-09-15 Atrix Laboratories, Inc. Biologisch abbaubarer Wundverband in Form eines Sprühfilms und Verfahren zu seiner Herstellung
WO1994016085A2 (en) 1992-12-30 1994-07-21 Zymogenetics, Inc. Hybrid proteins having cross-linking and tissue-binding activities
US5522895A (en) * 1993-07-23 1996-06-04 Rice University Biodegradable bone templates

Also Published As

Publication number Publication date
JPH10506811A (ja) 1998-07-07
DE69533404T3 (de) 2011-03-10
JP2006110370A (ja) 2006-04-27
EP0784490B2 (de) 2010-08-11
CA2201526C (en) 2008-12-09
CA2201526A1 (en) 1996-04-11
DE69533404T2 (de) 2005-09-08
ATE273721T1 (de) 2004-09-15
EP0784490A1 (de) 1997-07-23
AU3763195A (en) 1996-04-26
AU1287895A (en) 1996-04-26
EP0784490B1 (de) 2004-08-18
WO1996010374A1 (en) 1996-04-11
WO1996010428A1 (en) 1996-04-11

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: ANGIOTECH BIOMATERIALS CORP.(N.D.GES.D.STAATES DEL

8327 Change in the person/name/address of the patent owner

Owner name: ANGIOTECH PHARMACEUTICALS (US), INC., (N.D.GES, US

8366 Restricted maintained after opposition proceedings