DE69532753D1 - Multilamellare anzneistoffabgabesysteme - Google Patents

Multilamellare anzneistoffabgabesysteme

Info

Publication number
DE69532753D1
DE69532753D1 DE69532753T DE69532753T DE69532753D1 DE 69532753 D1 DE69532753 D1 DE 69532753D1 DE 69532753 T DE69532753 T DE 69532753T DE 69532753 T DE69532753 T DE 69532753T DE 69532753 D1 DE69532753 D1 DE 69532753D1
Authority
DE
Germany
Prior art keywords
multilamellar
delivery systems
hydrophobic
substance delivery
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69532753T
Other languages
English (en)
Other versions
DE69532753T2 (de
Inventor
W Belenduik
M Rudnic
A Mccarty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supernus Pharmaceuticals Inc
Original Assignee
Shire Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Laboratories Inc filed Critical Shire Laboratories Inc
Publication of DE69532753D1 publication Critical patent/DE69532753D1/de
Application granted granted Critical
Publication of DE69532753T2 publication Critical patent/DE69532753T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69532753T 1994-04-07 1995-04-07 Multilamellare anzneistoffabgabesysteme Expired - Lifetime DE69532753T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US224340 1994-04-07
US08/224,340 US5447729A (en) 1994-04-07 1994-04-07 Multilamellar drug delivery systems
PCT/US1995/004036 WO1995027479A1 (en) 1994-04-07 1995-04-07 Multilamellar drug delivery systems

Publications (2)

Publication Number Publication Date
DE69532753D1 true DE69532753D1 (de) 2004-04-29
DE69532753T2 DE69532753T2 (de) 2005-01-27

Family

ID=22840237

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532753T Expired - Lifetime DE69532753T2 (de) 1994-04-07 1995-04-07 Multilamellare anzneistoffabgabesysteme

Country Status (10)

Country Link
US (1) US5447729A (de)
EP (1) EP0754031B1 (de)
JP (1) JPH09511744A (de)
AT (1) ATE262317T1 (de)
AU (1) AU695053B2 (de)
CA (1) CA2187202C (de)
DE (1) DE69532753T2 (de)
ES (1) ES2217278T3 (de)
MX (1) MX9604490A (de)
WO (1) WO1995027479A1 (de)

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US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
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US5883103A (en) * 1995-06-07 1999-03-16 Shire Laboratories Inc. Oral acyclovir delivery
WO1997002815A1 (fr) * 1995-07-07 1997-01-30 Nippon Kayaku Kabushiki Kaisha Composition de flutamide
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JP2001507359A (ja) * 1997-01-03 2001-06-05 エラン コーポレーション ピーエルシー 徐放性シサプリドミニ錠剤製剤
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US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
DE19814014A1 (de) * 1997-12-19 1999-09-30 Krewel Meuselbach Gmbh Arzneipflanzentrockenextrakte
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
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US7070799B1 (en) * 1998-02-10 2006-07-04 Generex Pharmaceuticals, Inc. Method for administering insulin to the buccal region
US6221378B1 (en) 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
WO1999061456A1 (en) 1998-05-27 1999-12-02 University Of Iowa Research Foundation Sucrose-based surfactants and methods therefor
ITMI981528A1 (it) * 1998-07-03 2000-01-03 Recordati Ind Chimica E Farma Formulazioni topiche di aciclovir
ATE251449T1 (de) 1999-06-14 2003-10-15 Cosmo Spa Geschmacksmaskierte orale pharmazeutische zusammensetzungen mit kontrollierter abgabe
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
US7648696B2 (en) * 1999-08-20 2010-01-19 Unimed Pharmaceuticals, Llc Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
US6747058B1 (en) 1999-08-20 2004-06-08 Unimed Pharmaceuticals, Inc. Stable composition for inhalation therapy comprising delta-9-tetrahydrocannabinol and semiaqueous solvent therefor
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
WO2001054671A1 (fr) * 2000-01-27 2001-08-02 Tanabe Seiyaku Co., Ltd. Preparation a liberation prolongee et son procede de fabrication
US6596306B1 (en) * 2000-07-07 2003-07-22 David Ho Sue San Ho Drug delivery system:formulation for fat-soluble drugs
JP4593074B2 (ja) * 2000-10-11 2010-12-08 セフアロン・インコーポレーテツド モダフィニル化合物含有組成物
US6524615B2 (en) * 2001-02-21 2003-02-25 Kos Pharmaceuticals, Incorporated Controlled release pharmaceutical composition
US20030143272A1 (en) * 2001-03-14 2003-07-31 Waterman Kenneth C. Pharmaceutical tablet and process for making thereof
CN1633306A (zh) * 2001-10-16 2005-06-29 阿文尼尔药品公司 正－二十二烷醇的病毒抑制
FR2839645B1 (fr) * 2002-05-15 2005-08-05 Backert Marie Elisabeth Cuine Systeme multilamellaire pour l'administration de substances actives (en particulier des medicaments) par ingestion par la voie orale
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
LT2279729T (lt) * 2003-07-17 2016-10-10 Banner Life Sciences, LLC Kontroliuojamo atpalaidavimo preparatas
US7456306B2 (en) 2003-07-28 2008-11-25 Mallinckrodt Inc Stearate composition and method of production thereof
WO2005123043A2 (en) * 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
US20060088591A1 (en) * 2004-10-22 2006-04-27 Jinghua Yuan Tablets from a poorly compressible substance
AU2005314021B2 (en) * 2004-12-09 2010-02-11 Insys Therapeutics, Inc. Room-temperature stable dronabinol formulations
US20060240108A1 (en) * 2005-04-26 2006-10-26 Bernard Bobby L Cellulosic films incorporating a pharmaceutically acceptable plasticizer with enhanced wettability
US9743680B2 (en) 2005-10-14 2017-08-29 Wild Flavors, Inc. Microemulsions for use in food and beverage products
US8293270B2 (en) * 2005-10-26 2012-10-23 Banner Pharmacaps, Inc. Lipophilic vehicle-based dual controlled release matrix system
CN101360485B (zh) * 2005-10-26 2013-04-17 班纳制药公司 作为胶囊填充物的基于亲水性载体的双重控释基质系统
US9265724B2 (en) 2005-11-07 2016-02-23 Ram B. Murty Oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
US20080112895A1 (en) * 2006-08-04 2008-05-15 Insys Therapeutics Inc. Aqueous dronabinol formulations
CA2698752A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
US8394391B2 (en) * 2007-08-31 2013-03-12 University Of Utah Research Foundation Drug delivery vehicle that mimics viral properties
EP2200613B1 (de) 2007-09-21 2018-09-05 The Johns Hopkins University Phenazin-derivate und ihre verwendungen
EP2044932A1 (de) * 2007-10-04 2009-04-08 Laboratorios del Dr. Esteve S.A. Mechanische Schutzschicht für feste Darreichungsformen
WO2010079037A2 (de) * 2008-12-18 2010-07-15 Basf Se Wässrige dispersion umfassend pestizidpartikel und amphiphil
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
EP2480197B1 (de) 2009-09-25 2015-11-11 Dr. Reddy's Laboratories Ltd. Formulierungen mit triptanverbindungen
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
WO2012033478A1 (en) * 2010-09-07 2012-03-15 Murty Pharmaceuticals, Inc. An improved oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
EA201592236A1 (ru) * 2013-06-04 2016-06-30 Вайом Байосайнсиз Пвт. Лтд. Частицы с нанесенным покрытием и композиции, включающие такие частицы

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Also Published As

Publication number Publication date
WO1995027479A1 (en) 1995-10-19
EP0754031A4 (de) 2000-01-19
MX9604490A (es) 1997-11-29
ES2217278T3 (es) 2004-11-01
EP0754031A1 (de) 1997-01-22
US5447729A (en) 1995-09-05
JPH09511744A (ja) 1997-11-25
CA2187202A1 (en) 1995-10-19
EP0754031B1 (de) 2004-03-24
DE69532753T2 (de) 2005-01-27
ATE262317T1 (de) 2004-04-15
AU2276095A (en) 1995-10-30
CA2187202C (en) 2000-11-21
AU695053B2 (en) 1998-08-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SUPERNUS PHARMACEUTICALS, INC., ROCKVILLE, MD., US