JPS54122719A - Carcinostatic agent for oral administration - Google Patents

Carcinostatic agent for oral administration

Info

Publication number
JPS54122719A
JPS54122719A JP3038078A JP3038078A JPS54122719A JP S54122719 A JPS54122719 A JP S54122719A JP 3038078 A JP3038078 A JP 3038078A JP 3038078 A JP3038078 A JP 3038078A JP S54122719 A JPS54122719 A JP S54122719A
Authority
JP
Japan
Prior art keywords
carcinostatic agent
fatty acid
base
oral administration
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3038078A
Other languages
Japanese (ja)
Inventor
Ryuzo Okada
Kazue Hasegawa
Yorio Arakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP3038078A priority Critical patent/JPS54122719A/en
Publication of JPS54122719A publication Critical patent/JPS54122719A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

PURPOSE:To prepare a carcinostatic agent for oral administration having high absorbability, excellent remedying effect, and low side effects, by dissolving or dispersing a carcinostatic agent in a specific base such as glycerine fatty acid ester, etc. CONSTITUTION:A carcinostatic agent such as 5-fluorouracil, cytosine arabinoside, etc., is dissolved or dispersed in a base such as glycerine fatty acid ester (e.g. dioctyldecyl glyceride), an edible oil, a fatty acid (e.g. linolic acid), a fatty acid ester (e.g. propyl myristate), an oleovitamin (e.g. vitamin A), a phospholipid (e.g. ovolecithin), chlolic acid or its salt, to obtain the objective carcinostatic agent for oral administration. The original carcinostatic agent may be dispersed or dissolved in water, polyethylene glycol, etc., before dispersing in the base, or may be micro-encapsulated with the base.
JP3038078A 1978-03-16 1978-03-16 Carcinostatic agent for oral administration Pending JPS54122719A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3038078A JPS54122719A (en) 1978-03-16 1978-03-16 Carcinostatic agent for oral administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3038078A JPS54122719A (en) 1978-03-16 1978-03-16 Carcinostatic agent for oral administration

Publications (1)

Publication Number Publication Date
JPS54122719A true JPS54122719A (en) 1979-09-22

Family

ID=12302267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3038078A Pending JPS54122719A (en) 1978-03-16 1978-03-16 Carcinostatic agent for oral administration

Country Status (1)

Country Link
JP (1) JPS54122719A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002076A1 (en) * 1982-11-26 1984-06-07 Fluidcarbon International Ab Method of preparing controlled-release preparations for biologically active materials and resulting compositions
JPS59122423A (en) * 1982-12-28 1984-07-14 Green Cross Corp:The Carcinostatic-containing fatty emulsion
JPS61500750A (en) * 1983-12-16 1986-04-17 ランゲ・アルフ information display device
AT388499B (en) * 1985-08-02 1989-06-26 Merz & Co Gmbh & Co METHOD FOR PRODUCING AN ANTIVIRAL AND ANTITUMOR COMPOSITION, AND THE USE THEREOF
US4943564A (en) * 1985-02-18 1990-07-24 Teijin Limited Intraarterial injection pharmaceuticals of 5-fluoro-2'-deoxyuridine esters
WO1993015729A1 (en) * 1992-02-07 1993-08-19 Tsumura & Co. Side-effect alleviant
JPH09511744A (en) * 1994-04-07 1997-11-25 ファーマヴィーン,インコーポレイテッド Multi-layer drug delivery system
JP2009155282A (en) * 2007-12-27 2009-07-16 Kowa Co Solid dispersion-containing pharmaceutical composition
JP2012512174A (en) * 2008-12-15 2012-05-31 バナー ファーマキャプス, インコーポレイテッド Method for enhancing the release and absorption of water-insoluble active agents
JP2013517269A (en) * 2010-01-14 2013-05-16 ウメクライン ムード エービー Pharmaceutical composition containing 3-beta-hydroxy-5-alpha-pregnan-20-one having improved shelf life and solubility characteristics

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002076A1 (en) * 1982-11-26 1984-06-07 Fluidcarbon International Ab Method of preparing controlled-release preparations for biologically active materials and resulting compositions
JPS59122423A (en) * 1982-12-28 1984-07-14 Green Cross Corp:The Carcinostatic-containing fatty emulsion
JPH0518806B2 (en) * 1982-12-28 1993-03-15 Green Cross Corp
JPS61500750A (en) * 1983-12-16 1986-04-17 ランゲ・アルフ information display device
US4943564A (en) * 1985-02-18 1990-07-24 Teijin Limited Intraarterial injection pharmaceuticals of 5-fluoro-2'-deoxyuridine esters
AT388499B (en) * 1985-08-02 1989-06-26 Merz & Co Gmbh & Co METHOD FOR PRODUCING AN ANTIVIRAL AND ANTITUMOR COMPOSITION, AND THE USE THEREOF
WO1993015729A1 (en) * 1992-02-07 1993-08-19 Tsumura & Co. Side-effect alleviant
JPH09511744A (en) * 1994-04-07 1997-11-25 ファーマヴィーン,インコーポレイテッド Multi-layer drug delivery system
JP2009155282A (en) * 2007-12-27 2009-07-16 Kowa Co Solid dispersion-containing pharmaceutical composition
JP2012512174A (en) * 2008-12-15 2012-05-31 バナー ファーマキャプス, インコーポレイテッド Method for enhancing the release and absorption of water-insoluble active agents
US8920844B2 (en) 2008-12-15 2014-12-30 Banner Pharmacaps, Inc. Methods for enhancing the release and absorption of water insoluble active agents
US9566274B2 (en) 2008-12-15 2017-02-14 Banner Life Sciences Llc Methods for enhancing the release and absorption of water insoluble active agents
JP2013517269A (en) * 2010-01-14 2013-05-16 ウメクライン ムード エービー Pharmaceutical composition containing 3-beta-hydroxy-5-alpha-pregnan-20-one having improved shelf life and solubility characteristics
US9687496B2 (en) 2010-01-14 2017-06-27 Asarina Pharma Ab Pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties
US11534446B2 (en) 2010-01-14 2022-12-27 Asarina Pharma Ab Pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties

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