JPS54122719A - Carcinostatic agent for oral administration - Google Patents
Carcinostatic agent for oral administrationInfo
- Publication number
- JPS54122719A JPS54122719A JP3038078A JP3038078A JPS54122719A JP S54122719 A JPS54122719 A JP S54122719A JP 3038078 A JP3038078 A JP 3038078A JP 3038078 A JP3038078 A JP 3038078A JP S54122719 A JPS54122719 A JP S54122719A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic agent
- fatty acid
- base
- oral administration
- acid ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
PURPOSE:To prepare a carcinostatic agent for oral administration having high absorbability, excellent remedying effect, and low side effects, by dissolving or dispersing a carcinostatic agent in a specific base such as glycerine fatty acid ester, etc. CONSTITUTION:A carcinostatic agent such as 5-fluorouracil, cytosine arabinoside, etc., is dissolved or dispersed in a base such as glycerine fatty acid ester (e.g. dioctyldecyl glyceride), an edible oil, a fatty acid (e.g. linolic acid), a fatty acid ester (e.g. propyl myristate), an oleovitamin (e.g. vitamin A), a phospholipid (e.g. ovolecithin), chlolic acid or its salt, to obtain the objective carcinostatic agent for oral administration. The original carcinostatic agent may be dispersed or dissolved in water, polyethylene glycol, etc., before dispersing in the base, or may be micro-encapsulated with the base.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3038078A JPS54122719A (en) | 1978-03-16 | 1978-03-16 | Carcinostatic agent for oral administration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3038078A JPS54122719A (en) | 1978-03-16 | 1978-03-16 | Carcinostatic agent for oral administration |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54122719A true JPS54122719A (en) | 1979-09-22 |
Family
ID=12302267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3038078A Pending JPS54122719A (en) | 1978-03-16 | 1978-03-16 | Carcinostatic agent for oral administration |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54122719A (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984002076A1 (en) * | 1982-11-26 | 1984-06-07 | Fluidcarbon International Ab | Method of preparing controlled-release preparations for biologically active materials and resulting compositions |
JPS59122423A (en) * | 1982-12-28 | 1984-07-14 | Green Cross Corp:The | Carcinostatic-containing fatty emulsion |
JPS61500750A (en) * | 1983-12-16 | 1986-04-17 | ランゲ・アルフ | information display device |
AT388499B (en) * | 1985-08-02 | 1989-06-26 | Merz & Co Gmbh & Co | METHOD FOR PRODUCING AN ANTIVIRAL AND ANTITUMOR COMPOSITION, AND THE USE THEREOF |
US4943564A (en) * | 1985-02-18 | 1990-07-24 | Teijin Limited | Intraarterial injection pharmaceuticals of 5-fluoro-2'-deoxyuridine esters |
WO1993015729A1 (en) * | 1992-02-07 | 1993-08-19 | Tsumura & Co. | Side-effect alleviant |
JPH09511744A (en) * | 1994-04-07 | 1997-11-25 | ファーマヴィーン,インコーポレイテッド | Multi-layer drug delivery system |
JP2009155282A (en) * | 2007-12-27 | 2009-07-16 | Kowa Co | Solid dispersion-containing pharmaceutical composition |
JP2012512174A (en) * | 2008-12-15 | 2012-05-31 | バナー ファーマキャプス, インコーポレイテッド | Method for enhancing the release and absorption of water-insoluble active agents |
JP2013517269A (en) * | 2010-01-14 | 2013-05-16 | ウメクライン ムード エービー | Pharmaceutical composition containing 3-beta-hydroxy-5-alpha-pregnan-20-one having improved shelf life and solubility characteristics |
-
1978
- 1978-03-16 JP JP3038078A patent/JPS54122719A/en active Pending
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984002076A1 (en) * | 1982-11-26 | 1984-06-07 | Fluidcarbon International Ab | Method of preparing controlled-release preparations for biologically active materials and resulting compositions |
JPS59122423A (en) * | 1982-12-28 | 1984-07-14 | Green Cross Corp:The | Carcinostatic-containing fatty emulsion |
JPH0518806B2 (en) * | 1982-12-28 | 1993-03-15 | Green Cross Corp | |
JPS61500750A (en) * | 1983-12-16 | 1986-04-17 | ランゲ・アルフ | information display device |
US4943564A (en) * | 1985-02-18 | 1990-07-24 | Teijin Limited | Intraarterial injection pharmaceuticals of 5-fluoro-2'-deoxyuridine esters |
AT388499B (en) * | 1985-08-02 | 1989-06-26 | Merz & Co Gmbh & Co | METHOD FOR PRODUCING AN ANTIVIRAL AND ANTITUMOR COMPOSITION, AND THE USE THEREOF |
WO1993015729A1 (en) * | 1992-02-07 | 1993-08-19 | Tsumura & Co. | Side-effect alleviant |
JPH09511744A (en) * | 1994-04-07 | 1997-11-25 | ファーマヴィーン,インコーポレイテッド | Multi-layer drug delivery system |
JP2009155282A (en) * | 2007-12-27 | 2009-07-16 | Kowa Co | Solid dispersion-containing pharmaceutical composition |
JP2012512174A (en) * | 2008-12-15 | 2012-05-31 | バナー ファーマキャプス, インコーポレイテッド | Method for enhancing the release and absorption of water-insoluble active agents |
US8920844B2 (en) | 2008-12-15 | 2014-12-30 | Banner Pharmacaps, Inc. | Methods for enhancing the release and absorption of water insoluble active agents |
US9566274B2 (en) | 2008-12-15 | 2017-02-14 | Banner Life Sciences Llc | Methods for enhancing the release and absorption of water insoluble active agents |
JP2013517269A (en) * | 2010-01-14 | 2013-05-16 | ウメクライン ムード エービー | Pharmaceutical composition containing 3-beta-hydroxy-5-alpha-pregnan-20-one having improved shelf life and solubility characteristics |
US9687496B2 (en) | 2010-01-14 | 2017-06-27 | Asarina Pharma Ab | Pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties |
US11534446B2 (en) | 2010-01-14 | 2022-12-27 | Asarina Pharma Ab | Pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties |
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