IL105685AIL105685AIL10568593AIL105685AIL 105685 AIL105685 AIL 105685AIL 105685 AIL105685 AIL 105685AIL 10568593 AIL10568593 AIL 10568593AIL 105685 AIL105685 AIL 105685A
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Application filed by Clara Szalai Or Yehuda Harry FfiledCriticalClara Szalai Or Yehuda Harry F
Priority to IL105685ApriorityCriticalpatent/IL105685A/en
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Publication of IL105685ApublicationCriticalpatent/IL105685A/en
A multi-layered, microencapsulated pharmaceutical composition, comprising: a physiologically active pharmaceutical ingredient in combination with oil, water and lecithin, in the form of a microemulsified particle, vesicle, liposome or globule; an isolating film surrounding said microemulsified active ingredient; and a weakly and slowly soluble calcium compound asymmetrically coating said film-surrounded microemulsified active ingredient, said isolating film preventing interaction between said active ingredient and said calcium compound, as well as preventing interaction between said lecithin and said calcium compound, and said composition being delivered as a multiplicity of discrete microencapsulated units.